JP3961070B2 - カロチノイド組成物の製造方法 - Google Patents

カロチノイド組成物の製造方法 Download PDF

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Publication number
JP3961070B2
JP3961070B2 JP12382797A JP12382797A JP3961070B2 JP 3961070 B2 JP3961070 B2 JP 3961070B2 JP 12382797 A JP12382797 A JP 12382797A JP 12382797 A JP12382797 A JP 12382797A JP 3961070 B2 JP3961070 B2 JP 3961070B2
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Prior art keywords
carotenoid
powder
crystals
emulsion
amount
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Expired - Lifetime
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JP12382797A
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English (en)
Japanese (ja)
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JPH1046041A (ja
JPH1046041A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Inventor
レイ・エドワード・コワルスキー
ウイリアム・ヨセフ・メルゲンズ
レオナルド・ヨセフ・シャルピ
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DSM IP Assets BV
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DSM IP Assets BV
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Publication of JPH1046041A5 publication Critical patent/JPH1046041A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S516/00—Colloid systems and wetting agents; subcombinations thereof; processes of
    • Y10S516/924—Significant dispersive or manipulative operation or step in making or stabilizing colloid system

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fodder In General (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP12382797A 1996-05-14 1997-05-14 カロチノイド組成物の製造方法 Expired - Lifetime JP3961070B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1756896P 1996-05-14 1996-05-14
US60/017568 1996-05-14

Publications (3)

Publication Number Publication Date
JPH1046041A JPH1046041A (ja) 1998-02-17
JPH1046041A5 JPH1046041A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2005-04-07
JP3961070B2 true JP3961070B2 (ja) 2007-08-15

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Family Applications (1)

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JP12382797A Expired - Lifetime JP3961070B2 (ja) 1996-05-14 1997-05-14 カロチノイド組成物の製造方法

Country Status (10)

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US (1) US6093348A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0807431B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP3961070B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1079212C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE262316T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR9703134A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69728206T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0807431T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2216079T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN183685B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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US7521584B2 (en) * 2002-07-29 2009-04-21 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for the inhibition and amelioration of disease
US20050004235A1 (en) * 2002-07-29 2005-01-06 Lockwood Samuel Fournier Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease
US7320997B2 (en) * 2002-07-29 2008-01-22 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease
US20050059659A1 (en) * 2002-07-29 2005-03-17 Lockwood Samuel Fournier Carotenoid analogs or derivatives for controlling C-reactive protein levels
US7763649B2 (en) 2002-07-29 2010-07-27 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for controlling connexin 43 expression
US20050026874A1 (en) * 2002-07-29 2005-02-03 Lockwood Samuel Fournier Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease
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US20050049248A1 (en) * 2002-07-29 2005-03-03 Lockwood Samuel Fournier Carotenoid ether analogs or derivatives for controlling C-reactive protein levels
US20050148517A1 (en) * 2002-07-29 2005-07-07 Lockwood Samuel F. Carotenoid ether analogs or derivatives for controlling connexin 43 expression
US7723327B2 (en) 2002-07-29 2010-05-25 Cardax Pharmaceuticals, Inc. Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease
CN1708480B (zh) * 2002-07-29 2010-12-15 卡达克斯药物公司 用于抑制和改善疾病的类胡萝卜素结构类似物
US7375133B2 (en) * 2002-07-29 2008-05-20 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US7345091B2 (en) * 2002-07-29 2008-03-18 Cardax Pharmaceuticals, Inc. Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US20050059635A1 (en) * 2002-07-29 2005-03-17 Lockwood Samuel Fournier Carotenoid ester analogs or derivatives for controlling C-reactive protein levels
JP4773337B2 (ja) * 2003-03-27 2011-09-14 ディーエスエム アイピー アセッツ ビー．ブイ． ビーズレットの製造方法
US7332178B2 (en) 2003-04-25 2008-02-19 Abbott Laboratories Stable nutritional powder containing ascorbyl palmitate
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US20060058269A1 (en) * 2004-04-14 2006-03-16 Lockwood Samuel F Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation
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JP4562174B2 (ja) * 2004-08-23 2010-10-13 カゴメ株式会社 カロテノイド含有物の製造方法
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US10463061B2 (en) * 2004-11-19 2019-11-05 Dsm Ip Assets B.V. Modified plant gums for preparations of active ingredients
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CN100421650C (zh) * 2005-03-23 2008-10-01 浙江新和成股份有限公司 水分散性类胡萝卜素粉的制备方法
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BRPI0807967A2 (pt) * 2007-03-15 2014-06-10 Dsm Ip Assets Bv Partículas micronizadas estabilizadas
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JP5600513B2 (ja) * 2010-07-29 2014-10-01 理研ビタミン株式会社 クロセチン製剤の製造方法
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KR102221655B1 (ko) * 2012-10-18 2021-03-03 디에스엠 아이피 어셋츠 비.브이. 카로티노이드를 포함하는 비들렛
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CN112438950A (zh) * 2019-08-16 2021-03-05 北京化工大学 一种β-胡萝卜素透明水分散液及其制备方法
CN111471317B (zh) * 2020-03-26 2021-06-04 广东省农业科学院蚕业与农产品加工研究所 一种稳态化玉米黄色素及其制备方法
CN111838648B (zh) * 2020-06-16 2023-04-25 嘉必优生物技术（武汉）股份有限公司 一种生产纳米级类胡萝卜素乳液的装置及方法
KR20230051172A (ko) 2020-07-16 2023-04-17 아퀴타스 테라퓨틱스 인크. 지질 나노 입자에 사용하기 위한 양이온성 지질
CN112841645A (zh) * 2021-01-14 2021-05-28 江南大学 一种β-胡萝卜素微胶囊的制备方法
CN113426355A (zh) * 2021-06-25 2021-09-24 骏马化纤股份有限公司 一种化纤生产用油剂乳液自动化控制系统及制备方法
JP2024546952A (ja) 2021-12-16 2024-12-26 アクイタス セラピューティクス インコーポレイテッド 脂質ナノ粒子製剤に用いるための脂質
CN118525919A (zh) * 2023-02-22 2024-08-23 浙江可明生物医药有限公司 类胡萝卜素制剂的制备方法

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Also Published As

Publication number Publication date
JPH1046041A (ja) 1998-02-17
CN1079212C (zh) 2002-02-20
DE69728206T2 (de) 2005-03-10
DK0807431T3 (da) 2004-07-26
US6093348A (en) 2000-07-25
EP0807431A2 (en) 1997-11-19
EP0807431B1 (en) 2004-03-24
ES2216079T3 (es) 2004-10-16
IN183685B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2000-03-18
EP0807431A3 (en) 1998-08-12
DE69728206D1 (de) 2004-04-29
BR9703134A (pt) 1998-08-18
CN1176760A (zh) 1998-03-25
ATE262316T1 (de) 2004-04-15

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