DK0807431T3 - Fremgangsmåde til fremstilling af carotenoidpræparater - Google Patents

Fremgangsmåde til fremstilling af carotenoidpræparater

Info

Publication number
DK0807431T3
DK0807431T3 DK97106957T DK97106957T DK0807431T3 DK 0807431 T3 DK0807431 T3 DK 0807431T3 DK 97106957 T DK97106957 T DK 97106957T DK 97106957 T DK97106957 T DK 97106957T DK 0807431 T3 DK0807431 T3 DK 0807431T3
Authority
DK
Denmark
Prior art keywords
carotenoid
preparation
carotenoid preparations
disclosed
emulsion
Prior art date
Application number
DK97106957T
Other languages
Danish (da)
English (en)
Inventor
Leonard Joseph Scialpi
Ray Edward Kowalski
William Joseph Mergens
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Application granted granted Critical
Publication of DK0807431T3 publication Critical patent/DK0807431T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S516/00—Colloid systems and wetting agents; subcombinations thereof; processes of
    • Y10S516/924—Significant dispersive or manipulative operation or step in making or stabilizing colloid system

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fodder In General (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
DK97106957T 1996-05-14 1997-04-26 Fremgangsmåde til fremstilling af carotenoidpræparater DK0807431T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1756896P 1996-05-14 1996-05-14

Publications (1)

Publication Number Publication Date
DK0807431T3 true DK0807431T3 (da) 2004-07-26

Family

ID=21783319

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97106957T DK0807431T3 (da) 1996-05-14 1997-04-26 Fremgangsmåde til fremstilling af carotenoidpræparater

Country Status (10)

Country Link
US (1) US6093348A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0807431B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP3961070B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1079212C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE262316T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR9703134A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69728206T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0807431T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2216079T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN183685B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0876109T3 (da) * 1996-01-22 2003-10-20 Chr Hansen As Flydende farvegivende middel
NZ511792A (en) 1998-11-20 2003-08-29 Skyepharma Canada Inc Dispersible phospholipid stabilized microparticles
AU2001257115B2 (en) * 2000-04-20 2005-01-27 Rtp Pharma Inc. Improved water-insoluble drug particle process
US20030104090A1 (en) * 2000-05-05 2003-06-05 Levy Pedro E. Supplements containing annatto extracts and carotenoids and methods for using the same
WO2002024169A1 (en) * 2000-09-20 2002-03-28 Skyepharma Canada Inc. Spray drying process and compositions of fenofibrate
DE10064387A1 (de) * 2000-12-21 2002-06-27 Basf Ag Verfahren zur Herstellung von Trockenpulvern eines oder mehrerer Sauerstoff-haltiger Carotinoide
US7064101B2 (en) 2001-03-22 2006-06-20 Fuji Chemical Industry Co., Ltd. Stable astaxanthin-containing powdery compositions and process for producing the same
US6811801B2 (en) * 2001-12-12 2004-11-02 Abbott Laboratories Methods and compositions for brightening the color of thermally processed nutritionals
EP1519714B1 (en) 2002-06-28 2010-10-20 Protiva Biotherapeutics Inc. Method and apparatus for producing liposomes
US20050026874A1 (en) * 2002-07-29 2005-02-03 Lockwood Samuel Fournier Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease
US7723327B2 (en) 2002-07-29 2010-05-25 Cardax Pharmaceuticals, Inc. Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease
US20050143475A1 (en) * 2002-07-29 2005-06-30 Lockwood Samuel F. Carotenoid analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury
US20050059635A1 (en) * 2002-07-29 2005-03-17 Lockwood Samuel Fournier Carotenoid ester analogs or derivatives for controlling C-reactive protein levels
US7763649B2 (en) 2002-07-29 2010-07-27 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for controlling connexin 43 expression
US7345091B2 (en) * 2002-07-29 2008-03-18 Cardax Pharmaceuticals, Inc. Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US7521584B2 (en) * 2002-07-29 2009-04-21 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for the inhibition and amelioration of disease
US20050059659A1 (en) * 2002-07-29 2005-03-17 Lockwood Samuel Fournier Carotenoid analogs or derivatives for controlling C-reactive protein levels
US7320997B2 (en) * 2002-07-29 2008-01-22 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease
US20050004235A1 (en) * 2002-07-29 2005-01-06 Lockwood Samuel Fournier Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease
US7375133B2 (en) * 2002-07-29 2008-05-20 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
CN1708480B (zh) * 2002-07-29 2010-12-15 卡达克斯药物公司 用于抑制和改善疾病的类胡萝卜素结构类似物
US20050148517A1 (en) * 2002-07-29 2005-07-07 Lockwood Samuel F. Carotenoid ether analogs or derivatives for controlling connexin 43 expression
US20050049248A1 (en) * 2002-07-29 2005-03-03 Lockwood Samuel Fournier Carotenoid ether analogs or derivatives for controlling C-reactive protein levels
EP1605917B1 (en) 2003-03-27 2015-04-22 DSM IP Assets B.V. Process for the production of cross-linked gelatin microbeadlets
US7110827B2 (en) * 2003-04-25 2006-09-19 Medtronic, Inc. Electrical connectors for medical lead having weld-less wiring connection
US7332178B2 (en) 2003-04-25 2008-02-19 Abbott Laboratories Stable nutritional powder containing ascorbyl palmitate
US9247765B2 (en) * 2004-01-14 2016-02-02 Omniactive Health Technologies Limited Stable beadlets of lipophilic nutrients
US20060058269A1 (en) * 2004-04-14 2006-03-16 Lockwood Samuel F Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation
US7691901B2 (en) * 2004-04-14 2010-04-06 Cardax Pharmaceuticals Inc. Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation
JP4562174B2 (ja) * 2004-08-23 2010-10-13 カゴメ株式会社 カロテノイド含有物の製造方法
AU2005279201B2 (en) * 2004-08-31 2011-08-04 Akzo Nobel N.V. Method for pigment solubilisation, a pigment composition and its use
US10463061B2 (en) * 2004-11-19 2019-11-05 Dsm Ip Assets B.V. Modified plant gums for preparations of active ingredients
US8755258B2 (en) 2005-02-16 2014-06-17 Mitsubishi Electric Corporation Optical disc and optical disc device
CN100421650C (zh) * 2005-03-23 2008-10-01 浙江新和成股份有限公司 水分散性类胡萝卜素粉的制备方法
JP5639338B2 (ja) * 2005-07-27 2014-12-10 プロチバ バイオセラピューティクス インコーポレイティッド リポソームの製造システムおよび製造方法
EP1917227B1 (en) * 2005-08-15 2013-02-27 Phares Drug Delivery AG Crystal forms of astaxanthin
US7435846B2 (en) * 2006-08-18 2008-10-14 Industrial Organica, S.A. De C.V. Absorption and bioavailability of carotenoids, formulations and applications
AU2008225781B2 (en) * 2007-03-15 2013-09-12 Dsm Ip Assets B.V. Stabilized micronised particles
WO2009093595A1 (ja) * 2008-01-25 2009-07-30 Fujifilm Corporation カロテノイド含有エマルション組成物の製造方法、それにより得られるカロテノイド含有エマルション組成物並びにカロテノイド含有粉末組成物、該組成物を含む機能性食品及び化粧品
EP2210593A3 (en) 2009-01-21 2011-05-18 DSM IP Assets B.V. Tablettable formulations of vitamin A and derivatives thereof
WO2010111132A2 (en) 2009-03-27 2010-09-30 Bend Research, Inc. Spray-drying process
BR112012005247A2 (pt) * 2009-09-14 2019-09-24 Univ Hokkaido Nat Univ Corp agente antifitoviral
CN102933098B (zh) 2010-06-08 2017-03-29 三荣源有限公司 防止类胡萝卜色素附着于容器的方法
JP5600513B2 (ja) * 2010-07-29 2014-10-01 理研ビタミン株式会社 クロセチン製剤の製造方法
PT2611530T (pt) 2010-09-03 2019-05-09 Bend Res Inc Aparelho de secagem por pulverização e métodos de utilização do mesmo
EP2611529B1 (en) 2010-09-03 2019-01-23 Bend Research, Inc. Spray-drying method
WO2012040502A1 (en) 2010-09-24 2012-03-29 Bend Research, Inc. High-temperature spray drying process and apparatus
US20130317098A1 (en) * 2010-11-26 2013-11-28 Christian Schaefer Protective hydrocolloid for active ingredients
US20120157547A1 (en) 2010-12-21 2012-06-21 Ricardo Montoya-Olvera Compositions and applications of carotenoids of improved absorption and bioavailability
CN104736229B (zh) * 2012-10-18 2017-05-03 帝斯曼知识产权资产管理有限公司 包含类胡萝卜素的珠粒
WO2015044222A1 (en) * 2013-09-24 2015-04-02 Dsm Ip Assets B.V. Stable formulations for coloring beverages and food products
US11364203B2 (en) 2014-10-31 2022-06-21 Bend Reserch, Inc. Process for forming active domains dispersed in a matrix
KR102392072B1 (ko) * 2016-03-15 2022-04-29 디에스엠 아이피 어셋츠 비.브이. 코팅된 입자
ES2969807T3 (es) * 2016-03-24 2024-05-22 Basf Se Preparados de principios activos de múltiples fases
KR102411745B1 (ko) * 2016-07-19 2022-06-22 바스프 에스이 프로필 갈레이트-함유 비타민 제형
US11197493B2 (en) * 2017-09-12 2021-12-14 Omniactive Health Technologies Limited Stabilized fat soluble nutrient compositions and process for the preparation thereof
JP7225820B2 (ja) 2019-01-21 2023-02-21 株式会社アイシン 車両用開閉体制御装置
BR112021025185A2 (pt) * 2019-06-17 2022-02-01 Dsm Ip Assets Bv Forma de dosagem farmacêutica compreendendo metformina e citrato de cálcio
WO2020254396A1 (en) * 2019-06-17 2020-12-24 Dsm Ip Assets B.V. Solid pharmaceutical dosage form comprising spray dried vitamin b12
US20220304952A1 (en) * 2019-06-17 2022-09-29 Dsm Ip Assets B.V. Composition comprising metformin hci, vitamin b12 and at least one flow additive
CN112438950A (zh) * 2019-08-16 2021-03-05 北京化工大学 一种β-胡萝卜素透明水分散液及其制备方法
CN111471317B (zh) * 2020-03-26 2021-06-04 广东省农业科学院蚕业与农产品加工研究所 一种稳态化玉米黄色素及其制备方法
CN111838648B (zh) * 2020-06-16 2023-04-25 嘉必优生物技术（武汉）股份有限公司 一种生产纳米级类胡萝卜素乳液的装置及方法
AU2021308681A1 (en) 2020-07-16 2023-03-09 Acuitas Therapeutics, Inc. Cationic lipids for use in lipid nanoparticles
CN112841645A (zh) * 2021-01-14 2021-05-28 江南大学 一种β-胡萝卜素微胶囊的制备方法
CN113426355A (zh) * 2021-06-25 2021-09-24 骏马化纤股份有限公司 一种化纤生产用油剂乳液自动化控制系统及制备方法
CA3242402A1 (en) 2021-12-16 2023-06-22 Acuitas Therapeutics, Inc. Lipids for use in lipid nanoparticle formulations
CN118525919A (zh) * 2023-02-22 2024-08-23 浙江可明生物医药有限公司 类胡萝卜素制剂的制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2756177A (en) * 1953-03-09 1956-07-24 Hoffmann La Roche Process for making fat-soluble vitamin active powder
US2861891A (en) * 1956-12-13 1958-11-25 Hoffmann La Roche Water dispersible carotenoid compositions and process of making the same
DE1211911B (de) * 1959-09-08 1966-03-03 Hoffmann La Roche Verfahren zur Herstellung eines insbesondere zum Faerben von Lebens- und Futtermitteln geeigneten Carotinoidpraeparates
US3998753A (en) * 1974-08-13 1976-12-21 Hoffmann-La Roche Inc. Water dispersible carotenoid preparations and processes thereof
DE3048000A1 (de) * 1980-12-19 1982-07-15 Basf Ag Stabile injizierbare (beta)-carotin-solubilisate und verfahren zu ihrer herstellung
US4533254A (en) * 1981-04-17 1985-08-06 Biotechnology Development Corporation Apparatus for forming emulsions
US4908154A (en) * 1981-04-17 1990-03-13 Biotechnology Development Corporation Method of forming a microemulsion
DE3119383A1 (de) * 1981-05-15 1982-12-02 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von feinverteilten, pulverfoermigen carotinodpraeparaten
SE8604117D0 (sv) * 1986-09-29 1986-09-29 Kabivitrum Ab Composition
DE3702031A1 (de) * 1987-01-24 1988-08-04 Basf Ag Verfahren zur herstellung von mikrodispersen fischoelpraeparaten
DE59003205D1 (de) * 1989-07-25 1993-12-02 Hoffmann La Roche Verfahren zur Herstellung von Carotinoidpräparaten.
DK546289D0 (da) * 1989-11-02 1989-11-02 Danochemo As Carotenoidpulvere
DK19393D0 (da) * 1993-02-19 1993-02-19 Danochemo As Fremgangsmaade til fremstilling af et i vand dispergerbart pulverformigt carotenoidpraeparat
DE4329446A1 (de) * 1993-09-01 1995-03-02 Basf Ag Verfahren zur Herstellung von feinteiligen Farb- oder Wirkstoffzubereitungen
DE19649062A1 (de) * 1996-11-27 1998-05-28 Basf Ag Flüssige, mit Öl mischbare Carotinoid-Zubereitungen

Also Published As

Publication number Publication date
US6093348A (en) 2000-07-25
BR9703134A (pt) 1998-08-18
EP0807431B1 (en) 2004-03-24
DE69728206D1 (de) 2004-04-29
EP0807431A3 (en) 1998-08-12
EP0807431A2 (en) 1997-11-19
ES2216079T3 (es) 2004-10-16
IN183685B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2000-03-18
CN1079212C (zh) 2002-02-20
JP3961070B2 (ja) 2007-08-15
DE69728206T2 (de) 2005-03-10
ATE262316T1 (de) 2004-04-15
CN1176760A (zh) 1998-03-25
JPH1046041A (ja) 1998-02-17

Similar Documents

Publication Publication Date Title
DK0807431T3 (da) Fremgangsmåde til fremstilling af carotenoidpræparater
DK0805822T4 (da) Spraytørret erythropoietin
HUT54895A (en) Process for producing stabilized fgf composition
DE69717263D1 (de) Zubereitung mit verzögerter freisetzung und deren herstellung
AU2741295A (en) Method for preparing an influenza virus, antigens obtained and applications thereof
ES2066491T3 (es) Composiciones de colorantes en polvo y procedimiento para su preparacion.
NO974768D0 (no) Fremgangsmåte for fremstilling av et forbedret lavtstövende, lettflytende pigment
EP0837139A3 (en) Two step conversion of vegetable protein isoflavone conjugates to isoflavone aglucones
EP1044617A3 (de) Verfahren zur Herstellung fixierbarer Einlagestoffe
EP0475023A3 (en) Curable mixtures for the preparation of epoxy-networks, method for their preparation and their application
DK0566645T3 (da) Fremgangsmåde til fremstilling af et vegetabilsk proteinhydrolysat
ES2196743T3 (es) Sorbitol en polvo y su procedimiento de preparacion.
FI972474L (fi) Menetelmä selluloosaeetterin vesisuspension valmistamiseksi sekä kuiva seos, joka sopii käytettäväksi suspension valmistuksessa
DK559887A (da) Fremgangsmaade til fremstilling af carbinolderivater
MX9200793A (es) Tetrahidropirinas y metodo para su preparacion.
AU6412801A (en) A method of shaping heat-shrinkable materials
DE3881326D1 (de) Verfahren zur herstellung von paramunitaetsinducern.
NO302370B1 (no) Fremgangsmåte for fremstilling av en vandig emulsjon med snever dråpestörrelsesfordeling, og anvendelse av en slik emulsjon for fremstilling av en polymerdispersjon
EP0464203A4 (en) Hydraulic substance, method of producing and curing the same, curing chamber, and paint
GB8618114D0 (en) Joining of pipes
NO930519L (no) Fremgangsmaate for fremstilling av mikrokuleholdige termostivende harpiksmaterialer
AU7408591A (en) Plasticizing resins, aqueous dispersions thereof and methods of making the same
ATA251486A (de) Verfahren zur herstellung von neuen loeslichen und/oder schmelzbaren polyamidimid-polyimidblockcopolymeren
EP0362638A3 (en) Method of preparing symmetrical and unsymmetrical monoacetals of aromatic 1,2-diketones
DE69516331D1 (de) Verfahren zur Einstellung von Pigmentteilchen, Pigment und Färbepräparat