JP3328341B2 - 新規な巨核球増幅因子 - Google Patents

新規な巨核球増幅因子

Info

Publication number
JP3328341B2
JP3328341B2 JP34215192A JP34215192A JP3328341B2 JP 3328341 B2 JP3328341 B2 JP 3328341B2 JP 34215192 A JP34215192 A JP 34215192A JP 34215192 A JP34215192 A JP 34215192A JP 3328341 B2 JP3328341 B2 JP 3328341B2
Authority
JP
Japan
Prior art keywords
megakaryocyte
meg
amplification factor
pot
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP34215192A
Other languages
English (en)
Japanese (ja)
Other versions
JPH05331200A (ja
Inventor
希 山口
匡義 大枝
有宏 服部
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to JP34215192A priority Critical patent/JP3328341B2/ja
Publication of JPH05331200A publication Critical patent/JPH05331200A/ja
Application granted granted Critical
Publication of JP3328341B2 publication Critical patent/JP3328341B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Amplifiers (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP34215192A 1991-12-27 1992-12-22 新規な巨核球増幅因子 Expired - Fee Related JP3328341B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP34215192A JP3328341B2 (ja) 1991-12-27 1992-12-22 新規な巨核球増幅因子

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP36152291 1991-12-27
JP12251892 1992-03-31
JP4-122518 1992-03-31
JP3-361522 1992-03-31
JP34215192A JP3328341B2 (ja) 1991-12-27 1992-12-22 新規な巨核球増幅因子

Publications (2)

Publication Number Publication Date
JPH05331200A JPH05331200A (ja) 1993-12-14
JP3328341B2 true JP3328341B2 (ja) 2002-09-24

Family

ID=26459624

Family Applications (1)

Application Number Title Priority Date Filing Date
JP34215192A Expired - Fee Related JP3328341B2 (ja) 1991-12-27 1992-12-22 新規な巨核球増幅因子

Country Status (12)

Country Link
US (1) US5498698A (show.php)
EP (1) EP0621285B1 (show.php)
JP (1) JP3328341B2 (show.php)
KR (1) KR100233701B1 (show.php)
CN (1) CN1075148A (show.php)
AT (1) ATE221084T1 (show.php)
AU (1) AU658040B2 (show.php)
CA (1) CA2126680C (show.php)
DE (1) DE69232698T2 (show.php)
ES (1) ES2180542T3 (show.php)
TW (1) TW224975B (show.php)
WO (1) WO1993013132A1 (show.php)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL107366A (en) * 1992-10-23 2003-03-12 Chugai Pharmaceutical Co Ltd Genes coding for megakaryocyte potentiator
US5795569A (en) * 1994-03-31 1998-08-18 Amgen Inc. Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
KR100303810B1 (ko) * 1994-03-31 2001-12-01 스티븐 엠. 오드리 거핵구성장및분화를자극하기위한조성물및방법
US7375183B1 (en) * 1996-01-05 2008-05-20 The United States Of America As Represented By The Department Of Health And Human Services Mesothelin, immunogenic peptides derived therefrom, and compositions comprising mesothelin, or immunogenic peptides thereof
EP0871492B1 (en) * 1996-01-05 2003-11-26 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services Mesothelium antigen and methods and kits for targeting it
US6809184B1 (en) * 1997-12-01 2004-10-26 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Antibodies, including FV molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their use
WO2000057891A1 (en) 1999-03-30 2000-10-05 Trustees Of Boston University Compositions and methods for producing platelets and/or proplatelets from megakaryocytes
EP2011801A1 (en) 1999-05-27 2009-01-07 Government of the United States as represented by the Secretary, Department of Health and Human Services Immunoconjugates having high binding affinity
US20090110702A1 (en) * 2002-07-12 2009-04-30 The Johns Hopkins University Mesothelin Vaccines and Model Systems and Control of Tumors
EP1575500A4 (en) * 2002-07-12 2007-01-03 Univ Johns Hopkins MESOTHELIN VACCINE AND MODEL SYSTEMS
US9200036B2 (en) 2002-07-12 2015-12-01 The Johns Hopkins University Mesothelin vaccines and model systems
US20040180387A1 (en) * 2003-03-13 2004-09-16 Fujirebio Diagnostics, Inc. Detection of urinary mesothelin-/megakaryocyte potentiating factor-related peptides for assessment of ovarian cancer
BRPI0816014A8 (pt) 2007-10-01 2018-06-19 Bristol Myers Squibb Co anticorpo humano monoclonal isolado, composição, conjugado anticorpo-molécula parceiro, mólecula isolada de ácido nucléico, vetor de expressão, célula hospedeira, método para preparar um anticorpo anti-mesotelina, método de inibição do crescimento de uma célula tumoral expressando a mesotelina, método de tratamento do câncer em um indivíduo, anticorpo anti-mesotelina isolado, e método de inibir o crescimento de uma célula expressando a mesotelina

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU646530B2 (en) * 1990-12-28 1994-02-24 Asahi Kasei Kogyo Kabushiki Kaisha Novel megakaryocyte amplifier and production thereof
JPH04295500A (ja) * 1991-03-26 1992-10-20 Asahi Chem Ind Co Ltd 新規な巨核球増幅因子とその製法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Ｊ．Ｂｉｏｌ．Ｃｈｅｍ．，１９８７年 ３月 ５日，２６２（７），３２６２−３２６８
Ｊ．Ｂｉｏｌ．Ｃｈｅｍ．，１９９４年 １月１４日，２６９（２），８０５−８０８
Ｊ．Ｂｉｏｌ．Ｃｈｅｍ．，１９９５年 ９月１５日，２７０（３７），２１９８４−２１９９０

Also Published As

Publication number Publication date
KR940703858A (ko) 1994-12-12
US5498698A (en) 1996-03-12
CN1075148A (zh) 1993-08-11
DE69232698T2 (de) 2003-03-20
ES2180542T3 (es) 2003-02-16
CA2126680A1 (en) 1993-07-08
DE69232698D1 (de) 2002-08-29
EP0621285A1 (en) 1994-10-26
CA2126680C (en) 2002-10-08
ATE221084T1 (de) 2002-08-15
AU658040B2 (en) 1995-03-30
AU3172193A (en) 1993-07-28
EP0621285B1 (en) 2002-07-24
TW224975B (show.php) 1994-06-11
EP0621285A4 (en) 1995-05-24
JPH05331200A (ja) 1993-12-14
WO1993013132A1 (fr) 1993-07-08
KR100233701B1 (ko) 1999-12-01

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