JP3230699B2 - 心臓保護トコフェロ−ル類似体 - Google Patents

心臓保護トコフェロ−ル類似体

Info

Publication number
JP3230699B2
JP3230699B2 JP28704592A JP28704592A JP3230699B2 JP 3230699 B2 JP3230699 B2 JP 3230699B2 JP 28704592 A JP28704592 A JP 28704592A JP 28704592 A JP28704592 A JP 28704592A JP 3230699 B2 JP3230699 B2 JP 3230699B2
Authority
JP
Japan
Prior art keywords
alkyl
compound
benzopyran
dihydro
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP28704592A
Other languages
English (en)
Japanese (ja)
Other versions
JPH05310763A (ja
Inventor
マ−ティン グリサ−ル ジョアン
アン ペティ− マ−ガレット
ボルケニス フランク
Original Assignee
メレル ファ−マス−ティカルズ インコ−ポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by メレル ファ−マス−ティカルズ インコ−ポレイテッド filed Critical メレル ファ−マス−ティカルズ インコ−ポレイテッド
Publication of JPH05310763A publication Critical patent/JPH05310763A/ja
Application granted granted Critical
Publication of JP3230699B2 publication Critical patent/JP3230699B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Inspection Of Paper Currency And Valuable Securities (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Credit Cards Or The Like (AREA)
  • Noodles (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Fire-Detection Mechanisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
JP28704592A 1991-10-02 1992-10-02 心臓保護トコフェロ−ル類似体 Expired - Fee Related JP3230699B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR91402630.7 1991-10-02
EP91402630A EP0535283A1 (en) 1991-10-02 1991-10-02 Cardioprotective tocopherol analogs

Publications (2)

Publication Number Publication Date
JPH05310763A JPH05310763A (ja) 1993-11-22
JP3230699B2 true JP3230699B2 (ja) 2001-11-19

Family

ID=8208620

Family Applications (1)

Application Number Title Priority Date Filing Date
JP28704592A Expired - Fee Related JP3230699B2 (ja) 1991-10-02 1992-10-02 心臓保護トコフェロ−ル類似体

Country Status (17)

Country Link
EP (2) EP0535283A1 (enExample)
JP (1) JP3230699B2 (enExample)
KR (1) KR100253108B1 (enExample)
AT (1) ATE163421T1 (enExample)
AU (1) AU652077B2 (enExample)
CA (1) CA2079289C (enExample)
DE (1) DE69224501T2 (enExample)
DK (1) DK0536036T3 (enExample)
ES (1) ES2115656T3 (enExample)
FI (1) FI105552B (enExample)
GR (1) GR3026242T3 (enExample)
HU (1) HU215123B (enExample)
IL (1) IL103305A0 (enExample)
NO (1) NO923840L (enExample)
NZ (1) NZ244549A (enExample)
TW (1) TW224970B (enExample)
ZA (1) ZA927429B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7813042B2 (en) 2005-09-12 2010-10-12 Sharp Kabushiki Kaisha Multiple-view directional display
US8687273B2 (en) 2006-09-07 2014-04-01 Sharp Kabushiki Kaisha Image display device, electronic device, and parallax barrier element

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5510373A (en) * 1992-04-06 1996-04-23 Merrell Pharmaceuticals Inc. Cardioprotective agents
US5721233A (en) * 1992-04-06 1998-02-24 Merrell Pharmaceuticals Inc. Derivatives of 2,3-dihydro benzofuranols
US5545660A (en) * 1992-04-07 1996-08-13 Merrell Pharmaceuticals Inc. Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans
DE69830338T2 (de) * 1997-11-25 2006-02-02 Antipodean Biotechnology Ltd. Antioxidantien mit spezifischer wirkung auf mitochondrien
AUPR549901A0 (en) 2001-06-06 2001-07-12 Vital Health Sciences Pty Ltd Topical formulation containing tocopheryl phosphates
US8008345B2 (en) 2001-07-27 2011-08-30 Vital Health Sciences Pty. Ltd. Dermal therapy using phosphate derivatives of electron transfer agents
EP1374882B1 (de) * 2002-06-19 2008-10-01 Cognis IP Management GmbH Verwendung von Wirkstoffgemischen zur Herstellung eines Medikamentes gegen rheumatische Arthritis
AU2002950713A0 (en) 2002-08-09 2002-09-12 Vital Health Sciences Pty Ltd Carrier
US7888335B2 (en) 2003-08-22 2011-02-15 Antipodean Pharmaceuticals, Inc. Mitoquinone derivatives used as mitochondrially targeted antioxidants
US7888334B2 (en) 2003-08-22 2011-02-15 Antipodean Pharmaceuticals, Inc. Mitoquinone derivatives used as mitochondrially targeted antioxidants
US20050065099A1 (en) 2003-09-19 2005-03-24 Gail Walkinshaw Treatment of mitochondrial diseases
ATE495730T1 (de) 2004-03-03 2011-02-15 Vital Health Sciences Pty Ltd Alkaloid-formulierungen
US9168216B2 (en) 2005-06-17 2015-10-27 Vital Health Sciences Pty. Ltd. Carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof
US10071030B2 (en) 2010-02-05 2018-09-11 Phosphagenics Limited Carrier comprising non-neutralised tocopheryl phosphate
US8652511B2 (en) 2010-03-30 2014-02-18 Phosphagenics Limited Transdermal delivery patch
EP2685992A4 (en) 2011-03-15 2014-09-10 Phosphagenics Ltd AMINOCHINOLINE AS A KINASEHEMMER
CN108601732A (zh) 2015-12-09 2018-09-28 磷肌酸有限公司 药物制剂
US20190330260A1 (en) 2016-12-21 2019-10-31 Avecho Biotechnology Limited Process

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992021336A1 (en) 1991-06-05 1992-12-10 Merrell Dow Pharmaceuticals Inc. Cholesterol-lowering tocopherol analogs
US5500444A (en) 1989-11-14 1996-03-19 Hoechst Marion Roussel, Inc. Cardioprotective tocopherol analogs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62205091A (ja) * 1986-03-04 1987-09-09 Senjiyu Seiyaku Kk 新規なリン酸ジエステルならびにその塩、その製造法およびそれを含有する製剤
CA2002649C (en) * 1988-11-14 2000-06-06 Margaret Petty Cardioprotective tocopherol analogs

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5500444A (en) 1989-11-14 1996-03-19 Hoechst Marion Roussel, Inc. Cardioprotective tocopherol analogs
WO1992021336A1 (en) 1991-06-05 1992-12-10 Merrell Dow Pharmaceuticals Inc. Cholesterol-lowering tocopherol analogs

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Ｊ．Ｍｅｄ．Ｃｈｅｍ．，３４（１），２５７−６０（１９９１）

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7813042B2 (en) 2005-09-12 2010-10-12 Sharp Kabushiki Kaisha Multiple-view directional display
US8687273B2 (en) 2006-09-07 2014-04-01 Sharp Kabushiki Kaisha Image display device, electronic device, and parallax barrier element

Also Published As

Publication number Publication date
ATE163421T1 (de) 1998-03-15
KR100253108B1 (ko) 2000-05-01
AU2538392A (en) 1993-04-08
AU652077B2 (en) 1994-08-11
NO923840L (no) 1993-04-05
FI105552B (fi) 2000-09-15
TW224970B (enExample) 1994-06-11
DE69224501T2 (de) 1998-06-25
NO923840D0 (no) 1992-10-01
EP0535283A1 (en) 1993-04-07
DK0536036T3 (da) 1998-03-16
FI924424L (fi) 1993-04-03
EP0536036A1 (en) 1993-04-07
CA2079289C (en) 2003-02-18
NZ244549A (en) 1994-07-26
ZA927429B (en) 1993-04-07
FI924424A0 (fi) 1992-10-01
JPH05310763A (ja) 1993-11-22
HUT62592A (en) 1993-05-28
EP0536036B1 (en) 1998-02-25
HU215123B (hu) 1998-09-28
HU9203134D0 (en) 1992-12-28
DE69224501D1 (de) 1998-04-02
ES2115656T3 (es) 1998-07-01
IL103305A0 (en) 1993-02-21
GR3026242T3 (en) 1998-05-29
CA2079289A1 (en) 1993-04-03

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Legal Events

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LAPS Cancellation because of no payment of annual fees