AU652077B2 - Cardioprotective tocopherol analogs - Google Patents
Cardioprotective tocopherol analogs Download PDFInfo
- Publication number
- AU652077B2 AU652077B2 AU25383/92A AU2538392A AU652077B2 AU 652077 B2 AU652077 B2 AU 652077B2 AU 25383/92 A AU25383/92 A AU 25383/92A AU 2538392 A AU2538392 A AU 2538392A AU 652077 B2 AU652077 B2 AU 652077B2
- Authority
- AU
- Australia
- Prior art keywords
- compound
- alkyl
- reperfusion
- treatment
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
- C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Inspection Of Paper Currency And Valuable Securities (AREA)
- Noodles (AREA)
- Credit Cards Or The Like (AREA)
- Polyesters Or Polycarbonates (AREA)
- Cosmetics (AREA)
- Fire-Detection Mechanisms (AREA)
- Photoreceptors In Electrophotography (AREA)
- Absorbent Articles And Supports Therefor (AREA)
- Medicines Containing Plant Substances (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP91402630A EP0535283A1 (en) | 1991-10-02 | 1991-10-02 | Cardioprotective tocopherol analogs |
| EP91402630 | 1991-10-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2538392A AU2538392A (en) | 1993-04-08 |
| AU652077B2 true AU652077B2 (en) | 1994-08-11 |
Family
ID=8208620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU25383/92A Ceased AU652077B2 (en) | 1991-10-02 | 1992-09-28 | Cardioprotective tocopherol analogs |
Country Status (17)
| Country | Link |
|---|---|
| EP (2) | EP0535283A1 (enExample) |
| JP (1) | JP3230699B2 (enExample) |
| KR (1) | KR100253108B1 (enExample) |
| AT (1) | ATE163421T1 (enExample) |
| AU (1) | AU652077B2 (enExample) |
| CA (1) | CA2079289C (enExample) |
| DE (1) | DE69224501T2 (enExample) |
| DK (1) | DK0536036T3 (enExample) |
| ES (1) | ES2115656T3 (enExample) |
| FI (1) | FI105552B (enExample) |
| GR (1) | GR3026242T3 (enExample) |
| HU (1) | HU215123B (enExample) |
| IL (1) | IL103305A0 (enExample) |
| NO (1) | NO923840L (enExample) |
| NZ (1) | NZ244549A (enExample) |
| TW (1) | TW224970B (enExample) |
| ZA (1) | ZA927429B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5721233A (en) * | 1992-04-06 | 1998-02-24 | Merrell Pharmaceuticals Inc. | Derivatives of 2,3-dihydro benzofuranols |
| US5510373A (en) * | 1992-04-06 | 1996-04-23 | Merrell Pharmaceuticals Inc. | Cardioprotective agents |
| US5545660A (en) * | 1992-04-07 | 1996-08-13 | Merrell Pharmaceuticals Inc. | Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans |
| CN1318434C (zh) * | 1997-11-25 | 2007-05-30 | 安迪珀蒂恩生物工艺学有限公司 | 线粒体靶向的抗氧剂 |
| AUPR549901A0 (en) | 2001-06-06 | 2001-07-12 | Vital Health Sciences Pty Ltd | Topical formulation containing tocopheryl phosphates |
| MXPA04000654A (es) | 2001-07-27 | 2004-03-19 | Vital Health Sciences Pty Ltd | Terapia dermica usando derivados de fosfato de agente de transferencia de electrones. |
| EP1374882B1 (de) * | 2002-06-19 | 2008-10-01 | Cognis IP Management GmbH | Verwendung von Wirkstoffgemischen zur Herstellung eines Medikamentes gegen rheumatische Arthritis |
| AU2002950713A0 (en) | 2002-08-09 | 2002-09-12 | Vital Health Sciences Pty Ltd | Carrier |
| KR101003960B1 (ko) | 2003-08-22 | 2010-12-30 | 안티포딘 파마슈티칼스, 인코포레이티드 | 미토콘드리아 표적화 산화방지제로서 사용되는 미토퀴논 유도체를 포함하는 약제학적 조성물 |
| US7888334B2 (en) | 2003-08-22 | 2011-02-15 | Antipodean Pharmaceuticals, Inc. | Mitoquinone derivatives used as mitochondrially targeted antioxidants |
| WO2005033092A1 (en) | 2003-09-19 | 2005-04-14 | Galileo Pharmaceuticals, Inc. | Chroman derivatives |
| RU2477136C2 (ru) | 2004-03-03 | 2013-03-10 | Вайтал Хэлф Сайнсис Пти Лтд | Алкалоидные составы |
| US9168216B2 (en) | 2005-06-17 | 2015-10-27 | Vital Health Sciences Pty. Ltd. | Carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof |
| US7813042B2 (en) | 2005-09-12 | 2010-10-12 | Sharp Kabushiki Kaisha | Multiple-view directional display |
| WO2008029891A1 (en) | 2006-09-07 | 2008-03-13 | Sharp Kabushiki Kaisha | Image display device, electronic device, and parallax barrier element |
| WO2011094814A1 (en) | 2010-02-05 | 2011-08-11 | Phosphagenics Limited | Carrier comprising non-neutralised tocopheryl phosphate |
| CA2794734C (en) | 2010-03-30 | 2017-12-12 | Phosphagenics Limited | Transdermal delivery patch |
| WO2012122586A1 (en) | 2011-03-15 | 2012-09-20 | Phosphagenics Limited | New composition |
| US10973761B2 (en) | 2015-12-09 | 2021-04-13 | Phosphagenics Limited | Pharmaceutical formulation |
| JP7198754B2 (ja) | 2016-12-21 | 2023-01-04 | アベーチョ バイオテクノロジー リミテッド | 方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62205091A (ja) * | 1986-03-04 | 1987-09-09 | Senjiyu Seiyaku Kk | 新規なリン酸ジエステルならびにその塩、その製造法およびそれを含有する製剤 |
| CA2002649C (en) * | 1988-11-14 | 2000-06-06 | Margaret Petty | Cardioprotective tocopherol analogs |
| US5500444A (en) | 1989-11-14 | 1996-03-19 | Hoechst Marion Roussel, Inc. | Cardioprotective tocopherol analogs |
| US5135945A (en) | 1991-06-05 | 1992-08-04 | Merrell Dow Pharmaceuticals Inc. | Cholesterol-lowering tocopherol analogs |
-
1991
- 1991-10-02 EP EP91402630A patent/EP0535283A1/en not_active Withdrawn
-
1992
- 1992-09-28 AU AU25383/92A patent/AU652077B2/en not_active Ceased
- 1992-09-28 ZA ZA927429A patent/ZA927429B/xx unknown
- 1992-09-28 CA CA002079289A patent/CA2079289C/en not_active Expired - Fee Related
- 1992-09-29 EP EP92402656A patent/EP0536036B1/en not_active Expired - Lifetime
- 1992-09-29 ES ES92402656T patent/ES2115656T3/es not_active Expired - Lifetime
- 1992-09-29 DK DK92402656.0T patent/DK0536036T3/da active
- 1992-09-29 NZ NZ24454992A patent/NZ244549A/en unknown
- 1992-09-29 TW TW081107688A patent/TW224970B/zh active
- 1992-09-29 AT AT92402656T patent/ATE163421T1/de not_active IP Right Cessation
- 1992-09-29 DE DE69224501T patent/DE69224501T2/de not_active Expired - Fee Related
- 1992-09-30 IL IL103305A patent/IL103305A0/xx unknown
- 1992-10-01 FI FI924424A patent/FI105552B/fi active
- 1992-10-01 NO NO92923840A patent/NO923840L/no unknown
- 1992-10-01 HU HU9203134A patent/HU215123B/hu not_active IP Right Cessation
- 1992-10-01 KR KR1019920018013A patent/KR100253108B1/ko not_active Expired - Fee Related
- 1992-10-02 JP JP28704592A patent/JP3230699B2/ja not_active Expired - Fee Related
-
1998
- 1998-02-26 GR GR980400390T patent/GR3026242T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO923840L (no) | 1993-04-05 |
| CA2079289C (en) | 2003-02-18 |
| FI924424A0 (fi) | 1992-10-01 |
| JPH05310763A (ja) | 1993-11-22 |
| FI105552B (fi) | 2000-09-15 |
| HU9203134D0 (en) | 1992-12-28 |
| TW224970B (enExample) | 1994-06-11 |
| HUT62592A (en) | 1993-05-28 |
| EP0536036B1 (en) | 1998-02-25 |
| EP0536036A1 (en) | 1993-04-07 |
| EP0535283A1 (en) | 1993-04-07 |
| DE69224501T2 (de) | 1998-06-25 |
| IL103305A0 (en) | 1993-02-21 |
| ES2115656T3 (es) | 1998-07-01 |
| JP3230699B2 (ja) | 2001-11-19 |
| DK0536036T3 (da) | 1998-03-16 |
| ATE163421T1 (de) | 1998-03-15 |
| CA2079289A1 (en) | 1993-04-03 |
| AU2538392A (en) | 1993-04-08 |
| NZ244549A (en) | 1994-07-26 |
| KR100253108B1 (ko) | 2000-05-01 |
| FI924424L (fi) | 1993-04-03 |
| NO923840D0 (no) | 1992-10-01 |
| GR3026242T3 (en) | 1998-05-29 |
| ZA927429B (en) | 1993-04-07 |
| HU215123B (hu) | 1998-09-28 |
| DE69224501D1 (de) | 1998-04-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0536036B1 (en) | Cardioprotective tocopherol analogs | |
| AU620660B2 (en) | Cardioprotective tocopherol analogs | |
| KR100247213B1 (ko) | 4-알콕시-2,6-디-t-부틸페놀 유도체 | |
| Ingold et al. | Synthesis of 2R, 4′ R, 8′ R‐α‐tocopherols selectively labelled with deuterium | |
| EP0550292A1 (en) | Tissue protective tocopherol analogs | |
| EP0586518B1 (en) | Cholesterol-lowering tocopherol analogs | |
| JPH11501655A (ja) | ２，３−ジヒドロ−ベンゾフラノール誘導体の新規な製造法 | |
| EP0369083A1 (en) | Cardioprotective tocopherol analogs | |
| US5500444A (en) | Cardioprotective tocopherol analogs | |
| EP0369082A1 (en) | Cardioprotective tocopherol analogs | |
| IE910879A1 (en) | Novel ascorbic acid derivatives |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |