NO923840L - Cardiobeskyttende tocoferolanaloger - Google Patents
Cardiobeskyttende tocoferolanalogerInfo
- Publication number
- NO923840L NO923840L NO92923840A NO923840A NO923840L NO 923840 L NO923840 L NO 923840L NO 92923840 A NO92923840 A NO 92923840A NO 923840 A NO923840 A NO 923840A NO 923840 L NO923840 L NO 923840L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- tocoferol
- analogs
- cardio protective
- phenyl
- Prior art date
Links
- 230000003293 cardioprotective effect Effects 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000006545 (C1-C9) alkyl group Chemical group 0.000 abstract 1
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
- C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Inspection Of Paper Currency And Valuable Securities (AREA)
- Polyesters Or Polycarbonates (AREA)
- Credit Cards Or The Like (AREA)
- Noodles (AREA)
- Cosmetics (AREA)
- Photoreceptors In Electrophotography (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Absorbent Articles And Supports Therefor (AREA)
- Fire-Detection Mechanisms (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP91402630A EP0535283A1 (en) | 1991-10-02 | 1991-10-02 | Cardioprotective tocopherol analogs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO923840D0 NO923840D0 (no) | 1992-10-01 |
| NO923840L true NO923840L (no) | 1993-04-05 |
Family
ID=8208620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO92923840A NO923840L (no) | 1991-10-02 | 1992-10-01 | Cardiobeskyttende tocoferolanaloger |
Country Status (17)
| Country | Link |
|---|---|
| EP (2) | EP0535283A1 (enExample) |
| JP (1) | JP3230699B2 (enExample) |
| KR (1) | KR100253108B1 (enExample) |
| AT (1) | ATE163421T1 (enExample) |
| AU (1) | AU652077B2 (enExample) |
| CA (1) | CA2079289C (enExample) |
| DE (1) | DE69224501T2 (enExample) |
| DK (1) | DK0536036T3 (enExample) |
| ES (1) | ES2115656T3 (enExample) |
| FI (1) | FI105552B (enExample) |
| GR (1) | GR3026242T3 (enExample) |
| HU (1) | HU215123B (enExample) |
| IL (1) | IL103305A0 (enExample) |
| NO (1) | NO923840L (enExample) |
| NZ (1) | NZ244549A (enExample) |
| TW (1) | TW224970B (enExample) |
| ZA (1) | ZA927429B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5721233A (en) * | 1992-04-06 | 1998-02-24 | Merrell Pharmaceuticals Inc. | Derivatives of 2,3-dihydro benzofuranols |
| US5510373A (en) * | 1992-04-06 | 1996-04-23 | Merrell Pharmaceuticals Inc. | Cardioprotective agents |
| US5545660A (en) * | 1992-04-07 | 1996-08-13 | Merrell Pharmaceuticals Inc. | Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans |
| ATE296305T1 (de) * | 1997-11-25 | 2005-06-15 | Antipodean Biotechnology Ltd | Antioxidantien mit spezifischer wirkung auf mitochondrien |
| AUPR549901A0 (en) | 2001-06-06 | 2001-07-12 | Vital Health Sciences Pty Ltd | Topical formulation containing tocopheryl phosphates |
| BR0211673A (pt) | 2001-07-27 | 2004-07-13 | Vital Health Sciences Pty Ltd | Terapia dermal utilizando derivados de fosfato de agentes de transferência de elétrons |
| ATE409489T1 (de) * | 2002-06-19 | 2008-10-15 | Cognis Ip Man Gmbh | Verwendung von wirkstoffgemischen zur herstellung eines medikamentes gegen rheumatische arthritis |
| AU2002950713A0 (en) | 2002-08-09 | 2002-09-12 | Vital Health Sciences Pty Ltd | Carrier |
| JP4648319B2 (ja) | 2003-08-22 | 2011-03-09 | アンティポディーン ファーマシューティカルズ インコーポレイティド | ミトコンドリアを標的とする抗酸化剤として使用されるミトキノン誘導体 |
| US7888334B2 (en) | 2003-08-22 | 2011-02-15 | Antipodean Pharmaceuticals, Inc. | Mitoquinone derivatives used as mitochondrially targeted antioxidants |
| WO2005033093A1 (en) | 2003-09-19 | 2005-04-14 | Galileo Pharmaceuticals, Inc. | 7,8-bicycloalkyl-chroman derivatives |
| JP4847437B2 (ja) | 2004-03-03 | 2011-12-28 | バイタル ヘルス サイエンシズ プロプライアタリー リミティド | アルカロイド製剤 |
| US9168216B2 (en) | 2005-06-17 | 2015-10-27 | Vital Health Sciences Pty. Ltd. | Carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof |
| US7813042B2 (en) | 2005-09-12 | 2010-10-12 | Sharp Kabushiki Kaisha | Multiple-view directional display |
| US8687273B2 (en) | 2006-09-07 | 2014-04-01 | Sharp Kabushiki Kaisha | Image display device, electronic device, and parallax barrier element |
| EP2531047B1 (en) | 2010-02-05 | 2024-11-13 | Phosphagenics Limited | Carrier comprising non-neutralised tocopheryl phosphate |
| ES2829386T3 (es) | 2010-03-30 | 2021-05-31 | Phosphagenics Ltd | Parche de administración transdérmica |
| WO2012122586A1 (en) | 2011-03-15 | 2012-09-20 | Phosphagenics Limited | New composition |
| MX383940B (es) | 2015-12-09 | 2025-03-14 | Phosphagenics Ltd | Formulación farmacéutica que contiene tocol fosfato. |
| IL267006B2 (en) | 2016-12-21 | 2024-11-01 | Phosphagenics Ltd | Process for phosphorylation of a complex alcohol with p4o10 at high temperatures, and products thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62205091A (ja) * | 1986-03-04 | 1987-09-09 | Senjiyu Seiyaku Kk | 新規なリン酸ジエステルならびにその塩、その製造法およびそれを含有する製剤 |
| CA2002649C (en) * | 1988-11-14 | 2000-06-06 | Margaret Petty | Cardioprotective tocopherol analogs |
| US5500444A (en) | 1989-11-14 | 1996-03-19 | Hoechst Marion Roussel, Inc. | Cardioprotective tocopherol analogs |
| US5135945A (en) | 1991-06-05 | 1992-08-04 | Merrell Dow Pharmaceuticals Inc. | Cholesterol-lowering tocopherol analogs |
-
1991
- 1991-10-02 EP EP91402630A patent/EP0535283A1/en not_active Withdrawn
-
1992
- 1992-09-28 ZA ZA927429A patent/ZA927429B/xx unknown
- 1992-09-28 CA CA002079289A patent/CA2079289C/en not_active Expired - Fee Related
- 1992-09-28 AU AU25383/92A patent/AU652077B2/en not_active Ceased
- 1992-09-29 AT AT92402656T patent/ATE163421T1/de not_active IP Right Cessation
- 1992-09-29 DE DE69224501T patent/DE69224501T2/de not_active Expired - Fee Related
- 1992-09-29 TW TW081107688A patent/TW224970B/zh active
- 1992-09-29 EP EP92402656A patent/EP0536036B1/en not_active Expired - Lifetime
- 1992-09-29 NZ NZ24454992A patent/NZ244549A/en unknown
- 1992-09-29 DK DK92402656.0T patent/DK0536036T3/da active
- 1992-09-29 ES ES92402656T patent/ES2115656T3/es not_active Expired - Lifetime
- 1992-09-30 IL IL103305A patent/IL103305A0/xx unknown
- 1992-10-01 FI FI924424A patent/FI105552B/fi active
- 1992-10-01 KR KR1019920018013A patent/KR100253108B1/ko not_active Expired - Fee Related
- 1992-10-01 NO NO92923840A patent/NO923840L/no unknown
- 1992-10-01 HU HU9203134A patent/HU215123B/hu not_active IP Right Cessation
- 1992-10-02 JP JP28704592A patent/JP3230699B2/ja not_active Expired - Fee Related
-
1998
- 1998-02-26 GR GR980400390T patent/GR3026242T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2115656T3 (es) | 1998-07-01 |
| DK0536036T3 (da) | 1998-03-16 |
| CA2079289C (en) | 2003-02-18 |
| FI105552B (fi) | 2000-09-15 |
| ZA927429B (en) | 1993-04-07 |
| EP0535283A1 (en) | 1993-04-07 |
| FI924424L (fi) | 1993-04-03 |
| FI924424A0 (fi) | 1992-10-01 |
| CA2079289A1 (en) | 1993-04-03 |
| TW224970B (enExample) | 1994-06-11 |
| DE69224501T2 (de) | 1998-06-25 |
| AU652077B2 (en) | 1994-08-11 |
| HU215123B (hu) | 1998-09-28 |
| KR100253108B1 (ko) | 2000-05-01 |
| EP0536036B1 (en) | 1998-02-25 |
| GR3026242T3 (en) | 1998-05-29 |
| NO923840D0 (no) | 1992-10-01 |
| HU9203134D0 (en) | 1992-12-28 |
| JP3230699B2 (ja) | 2001-11-19 |
| JPH05310763A (ja) | 1993-11-22 |
| AU2538392A (en) | 1993-04-08 |
| NZ244549A (en) | 1994-07-26 |
| DE69224501D1 (de) | 1998-04-02 |
| EP0536036A1 (en) | 1993-04-07 |
| IL103305A0 (en) | 1993-02-21 |
| HUT62592A (en) | 1993-05-28 |
| ATE163421T1 (de) | 1998-03-15 |
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