NO923840L - Cardiobeskyttende tocoferolanaloger - Google Patents
Cardiobeskyttende tocoferolanalogerInfo
- Publication number
- NO923840L NO923840L NO92923840A NO923840A NO923840L NO 923840 L NO923840 L NO 923840L NO 92923840 A NO92923840 A NO 92923840A NO 923840 A NO923840 A NO 923840A NO 923840 L NO923840 L NO 923840L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- tocoferol
- analogs
- cardio protective
- phenyl
- Prior art date
Links
- 230000003293 cardioprotective effect Effects 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000006545 (C1-C9) alkyl group Chemical group 0.000 abstract 1
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
- C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Inspection Of Paper Currency And Valuable Securities (AREA)
- Cosmetics (AREA)
- Noodles (AREA)
- Polyesters Or Polycarbonates (AREA)
- Credit Cards Or The Like (AREA)
- Photoreceptors In Electrophotography (AREA)
- Fire-Detection Mechanisms (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Absorbent Articles And Supports Therefor (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP91402630A EP0535283A1 (en) | 1991-10-02 | 1991-10-02 | Cardioprotective tocopherol analogs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO923840D0 NO923840D0 (no) | 1992-10-01 |
| NO923840L true NO923840L (no) | 1993-04-05 |
Family
ID=8208620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO92923840A NO923840L (no) | 1991-10-02 | 1992-10-01 | Cardiobeskyttende tocoferolanaloger |
Country Status (17)
| Country | Link |
|---|---|
| EP (2) | EP0535283A1 (enExample) |
| JP (1) | JP3230699B2 (enExample) |
| KR (1) | KR100253108B1 (enExample) |
| AT (1) | ATE163421T1 (enExample) |
| AU (1) | AU652077B2 (enExample) |
| CA (1) | CA2079289C (enExample) |
| DE (1) | DE69224501T2 (enExample) |
| DK (1) | DK0536036T3 (enExample) |
| ES (1) | ES2115656T3 (enExample) |
| FI (1) | FI105552B (enExample) |
| GR (1) | GR3026242T3 (enExample) |
| HU (1) | HU215123B (enExample) |
| IL (1) | IL103305A0 (enExample) |
| NO (1) | NO923840L (enExample) |
| NZ (1) | NZ244549A (enExample) |
| TW (1) | TW224970B (enExample) |
| ZA (1) | ZA927429B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5721233A (en) * | 1992-04-06 | 1998-02-24 | Merrell Pharmaceuticals Inc. | Derivatives of 2,3-dihydro benzofuranols |
| US5510373A (en) * | 1992-04-06 | 1996-04-23 | Merrell Pharmaceuticals Inc. | Cardioprotective agents |
| US5545660A (en) * | 1992-04-07 | 1996-08-13 | Merrell Pharmaceuticals Inc. | Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans |
| CA2311318C (en) * | 1997-11-25 | 2011-11-01 | University Of Otago | Mitochondrially targeted antioxidants |
| AUPR549901A0 (en) | 2001-06-06 | 2001-07-12 | Vital Health Sciences Pty Ltd | Topical formulation containing tocopheryl phosphates |
| AU2002317053B2 (en) | 2001-07-27 | 2004-08-05 | Vital Health Sciences Pty Ltd | Dermal therapy using phosphate derivatives of electron transfer agents |
| DE50212837D1 (de) * | 2002-06-19 | 2008-11-13 | Cognis Ip Man Gmbh | Verwendung von Wirkstoffgemischen zur Herstellung eines Medikamentes gegen rheumatische Arthritis |
| AU2002950713A0 (en) | 2002-08-09 | 2002-09-12 | Vital Health Sciences Pty Ltd | Carrier |
| SG145715A1 (en) | 2003-08-22 | 2008-09-29 | Antipodean Pharmaceuticals Inc | Mitoquinone derivatives used as mitochondrially targeted antioxidants |
| US7888334B2 (en) | 2003-08-22 | 2011-02-15 | Antipodean Pharmaceuticals, Inc. | Mitoquinone derivatives used as mitochondrially targeted antioxidants |
| WO2005032544A1 (en) | 2003-09-19 | 2005-04-14 | Galileo Pharmaceuticals, Inc. | Treatment of mitochondrial diseases |
| DK1720551T3 (da) | 2004-03-03 | 2011-05-16 | Vital Health Sciences Pty Ltd | Alkaloidformuleringer |
| MX2007015949A (es) | 2005-06-17 | 2008-03-07 | Vital Health Sciences Pty Ltd | Un vehiculo que comprende uno o mas derivados de fosfato de di- y/o mono-(agentes de transferencia de electrones) o complejos de los mismos. |
| US7813042B2 (en) | 2005-09-12 | 2010-10-12 | Sharp Kabushiki Kaisha | Multiple-view directional display |
| EP2063308A4 (en) | 2006-09-07 | 2010-12-22 | Sharp Kk | IMAGE DISPLAY DEVICE, ELECTRONIC DEVICE, AND PARALLAX BARRIER ELEMENT |
| ES2999020T3 (en) | 2010-02-05 | 2025-02-24 | Phosphagenics Ltd | Carrier comprising non-neutralised tocopheryl phosphate |
| KR20130010473A (ko) | 2010-03-30 | 2013-01-28 | 포스파제닉스 리미티드 | 경피 전달 패치 |
| WO2012122586A1 (en) | 2011-03-15 | 2012-09-20 | Phosphagenics Limited | New composition |
| MX383940B (es) | 2015-12-09 | 2025-03-14 | Phosphagenics Ltd | Formulación farmacéutica que contiene tocol fosfato. |
| IL267006B2 (en) | 2016-12-21 | 2024-11-01 | Phosphagenics Ltd | Process for phosphorylation of a complex alcohol with p4o10 at high temperatures, and products thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62205091A (ja) * | 1986-03-04 | 1987-09-09 | Senjiyu Seiyaku Kk | 新規なリン酸ジエステルならびにその塩、その製造法およびそれを含有する製剤 |
| CA2002649C (en) * | 1988-11-14 | 2000-06-06 | Margaret Petty | Cardioprotective tocopherol analogs |
| US5500444A (en) | 1989-11-14 | 1996-03-19 | Hoechst Marion Roussel, Inc. | Cardioprotective tocopherol analogs |
| US5135945A (en) | 1991-06-05 | 1992-08-04 | Merrell Dow Pharmaceuticals Inc. | Cholesterol-lowering tocopherol analogs |
-
1991
- 1991-10-02 EP EP91402630A patent/EP0535283A1/en not_active Withdrawn
-
1992
- 1992-09-28 ZA ZA927429A patent/ZA927429B/xx unknown
- 1992-09-28 CA CA002079289A patent/CA2079289C/en not_active Expired - Fee Related
- 1992-09-28 AU AU25383/92A patent/AU652077B2/en not_active Ceased
- 1992-09-29 DE DE69224501T patent/DE69224501T2/de not_active Expired - Fee Related
- 1992-09-29 ES ES92402656T patent/ES2115656T3/es not_active Expired - Lifetime
- 1992-09-29 NZ NZ24454992A patent/NZ244549A/en unknown
- 1992-09-29 DK DK92402656.0T patent/DK0536036T3/da active
- 1992-09-29 TW TW081107688A patent/TW224970B/zh active
- 1992-09-29 EP EP92402656A patent/EP0536036B1/en not_active Expired - Lifetime
- 1992-09-29 AT AT92402656T patent/ATE163421T1/de not_active IP Right Cessation
- 1992-09-30 IL IL103305A patent/IL103305A0/xx unknown
- 1992-10-01 KR KR1019920018013A patent/KR100253108B1/ko not_active Expired - Fee Related
- 1992-10-01 NO NO92923840A patent/NO923840L/no unknown
- 1992-10-01 HU HU9203134A patent/HU215123B/hu not_active IP Right Cessation
- 1992-10-01 FI FI924424A patent/FI105552B/fi active
- 1992-10-02 JP JP28704592A patent/JP3230699B2/ja not_active Expired - Fee Related
-
1998
- 1998-02-26 GR GR980400390T patent/GR3026242T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL103305A0 (en) | 1993-02-21 |
| KR100253108B1 (ko) | 2000-05-01 |
| GR3026242T3 (en) | 1998-05-29 |
| NO923840D0 (no) | 1992-10-01 |
| HU9203134D0 (en) | 1992-12-28 |
| FI924424L (fi) | 1993-04-03 |
| ATE163421T1 (de) | 1998-03-15 |
| CA2079289A1 (en) | 1993-04-03 |
| DE69224501T2 (de) | 1998-06-25 |
| EP0536036A1 (en) | 1993-04-07 |
| EP0535283A1 (en) | 1993-04-07 |
| JP3230699B2 (ja) | 2001-11-19 |
| HUT62592A (en) | 1993-05-28 |
| JPH05310763A (ja) | 1993-11-22 |
| CA2079289C (en) | 2003-02-18 |
| NZ244549A (en) | 1994-07-26 |
| TW224970B (enExample) | 1994-06-11 |
| DK0536036T3 (da) | 1998-03-16 |
| ZA927429B (en) | 1993-04-07 |
| HU215123B (hu) | 1998-09-28 |
| EP0536036B1 (en) | 1998-02-25 |
| ES2115656T3 (es) | 1998-07-01 |
| AU652077B2 (en) | 1994-08-11 |
| DE69224501D1 (de) | 1998-04-02 |
| AU2538392A (en) | 1993-04-08 |
| FI924424A0 (fi) | 1992-10-01 |
| FI105552B (fi) | 2000-09-15 |
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