DE69500660D1 - Ophthalmische Zusammensetzung enthaltend ein 1,5-Benzoxathiepin-Derivat zur Behandlung von Glaukoma - Google Patents

Ophthalmische Zusammensetzung enthaltend ein 1,5-Benzoxathiepin-Derivat zur Behandlung von Glaukoma

Info

Publication number
DE69500660D1
DE69500660D1 DE69500660T DE69500660T DE69500660D1 DE 69500660 D1 DE69500660 D1 DE 69500660D1 DE 69500660 T DE69500660 T DE 69500660T DE 69500660 T DE69500660 T DE 69500660T DE 69500660 D1 DE69500660 D1 DE 69500660D1
Authority
DE
Germany
Prior art keywords
optionally substituted
hydrogen
treatment
ophthalmic composition
benzoxathiepin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69500660T
Other languages
English (en)
Other versions
DE69500660T2 (de
Inventor
Takahiro Ogawa
Takaaki Deguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Original Assignee
Senju Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd filed Critical Senju Pharmaceutical Co Ltd
Publication of DE69500660D1 publication Critical patent/DE69500660D1/de
Application granted granted Critical
Publication of DE69500660T2 publication Critical patent/DE69500660T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69500660T 1994-01-27 1995-01-25 Ophthalmische Zusammensetzung enthaltend ein 1,5-Benzoxathiepin-Derivat zur Behandlung von Glaukoma Expired - Fee Related DE69500660T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP747094 1994-01-27

Publications (2)

Publication Number Publication Date
DE69500660D1 true DE69500660D1 (de) 1997-10-16
DE69500660T2 DE69500660T2 (de) 1998-02-26

Family

ID=11666688

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69500660T Expired - Fee Related DE69500660T2 (de) 1994-01-27 1995-01-25 Ophthalmische Zusammensetzung enthaltend ein 1,5-Benzoxathiepin-Derivat zur Behandlung von Glaukoma

Country Status (9)

Country Link
US (1) US5538974A (de)
EP (1) EP0667156B1 (de)
KR (1) KR950032169A (de)
CN (1) CN1116928A (de)
AT (1) ATE157870T1 (de)
CA (1) CA2141176A1 (de)
DE (1) DE69500660T2 (de)
ES (1) ES2106573T3 (de)
TW (1) TW316235B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6960579B1 (en) 1998-05-19 2005-11-01 Alcon Manufacturing, Ltd. Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders
WO2000016761A2 (en) 1998-09-18 2000-03-30 Alcon Laboratories, Inc. Serotonergic 5ht2 agonists for treating glaucoma
DE60117247D1 (de) * 2000-03-31 2006-04-20 Purdue Research Foundation West Lafayette Phosphoramidat-prodrugs
FR2822467B1 (fr) * 2001-03-22 2003-12-12 Pf Medicament Derives benzoxathiepines et leur utilisation comme medicaments
EP1461030A4 (de) * 2001-12-14 2005-06-01 Alcon Inc Aminoalkyl-benzofuran-5-ol-verbindungen zur behandlung von glaukom
TW593302B (en) * 2001-12-20 2004-06-21 Alcon Inc Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma
WO2004009586A1 (en) * 2002-07-19 2004-01-29 Biovitrum Ab Novel piperazinyl-pyrazinone derivatives for the treatment of 5-ht2a receptor-related disorders
KR20050033654A (ko) * 2002-08-30 2005-04-12 알콘, 인코퍼레이티드 치환된 5-크로만-5-일-에틸아민 화합물 및 녹내장의 치료용그의 용도
WO2004054572A2 (en) * 2002-12-13 2004-07-01 Alcon, Inc. Novel benzopyran analogs and their use for the treatment of glaucoma
CN1835735B (zh) * 2003-08-20 2010-05-12 参天制药株式会社 微粒眼球筋膜下给药的药物释放系统
WO2005053688A1 (en) * 2003-11-26 2005-06-16 Alcon, Inc. Substituted furo[2,3-g] indazoles for the treatment of glaucoma
TW200520760A (en) * 2003-12-15 2005-07-01 Alcon Inc Substituted [1,4] oxazino [2,3-g] indazoles for the treatment of glaucoma
US7338972B1 (en) 2003-12-15 2008-03-04 Alcon, Inc. Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma
US7129257B1 (en) * 2003-12-15 2006-10-31 Alcon, Inc. Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma
US20050276867A1 (en) 2004-06-09 2005-12-15 Allergan, Inc. Stabilized compositions comprising a therapeutically active agent and an oxidizing preservative
US7425572B2 (en) * 2004-12-08 2008-09-16 Alcon, Inc. Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma
TW200744567A (en) * 2005-09-23 2007-12-16 Alcon Inc Phenylethylamine analogs and their use for treating glaucoma
US20070293475A1 (en) * 2006-06-20 2007-12-20 Alcon Manufacturing Ltd. Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma
WO2008048135A1 (fr) * 2006-10-20 2008-04-24 Limited Liability Company 'mitotechnology' Composition destinée à la régénération, la stimulation de la croissance et l'adaptation de plantes à tous types de facteurs de stress
EP2119436A4 (de) 2006-10-20 2010-03-03 Ltd Liability Company Mitotech Pharmazeutische zusammensetzungen zur verhinderung und behandlung von augenkrankheiten
WO2008094061A1 (fr) * 2007-01-29 2008-08-07 Limited Liability Company 'mitotechnology' Compositions pharmaceutiques et cosmétiques servant à accélérer le processus de cicatrisation de plaies et autres lésions superficielles
US8349902B2 (en) * 2007-01-29 2013-01-08 Mitotech Sa Pharmaceutical compositions useful for preventing and treating oncological diseases
EA016723B1 (ru) * 2007-02-27 2012-07-30 Дели Инститьют Оф Фармасьютикал Сайнсиз Энд Рисерч (Дипсар) Синергетическая травяная композиция, применяемая при глаукоме, и способ ее получения
US9439916B2 (en) * 2007-04-11 2016-09-13 Mitotech Sa Composition for decelerating the aging in the organism and for extending the life time thereof and the use of said composition
WO2009005386A1 (fr) 2007-06-29 2009-01-08 Limited Liability Company 'mitotechnology' Utilisation de compositions à adressage mitochondrial dans la prévention et le traitement de maldies cardio-vasculaires
WO2010056145A1 (ru) 2008-11-12 2010-05-20 Общество С Ограниченной Ответственностью "Митотехнология" Способ умеренного повышения протонной проводимости биологических мембран при помощи митохондриально- адресованных делокализованных катионов
UA104320C2 (ru) * 2009-06-10 2014-01-27 Общество С Ограниченной Ответственностью "Мимотех" Фармацевтическая композиция на основе митохондриально-адресованного антиоксиданта для применения в медицинской и ветеринарной офтальмологии
CN102791670A (zh) 2009-11-13 2012-11-21 米拓科技有限责任公司 基于定向于线粒体的抗氧化剂的药物物质
US9320690B2 (en) 2010-12-20 2016-04-26 Colgate-Palmolive Company Gelatin encapsulated oral care composition containing hydrophilic active, hydrophobic structuring agent and oil carrier
AU2012261854B2 (en) 2011-06-03 2017-11-16 Mitotech Sa Oral formulations of mitochondrially-targeted antioxidants and their preparation and use
CN112439071B (zh) * 2019-09-04 2022-05-20 武汉科福新药有限责任公司 透皮促渗组合物及其在噻吗洛尔制剂中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK166779B1 (da) * 1983-12-14 1993-07-12 Takeda Chemical Industries Ltd 1,5-benzoxatiepinderivater eller farmaceutisk acceptable salte deraf, samt farmaceutisk praeparat indeholdende en saadan forbindelse
EP0229467A1 (de) * 1985-12-10 1987-07-22 Takeda Chemical Industries, Ltd. 1,5-Benzoxathiepin-Derivate, deren Herstellung und Verwendung

Also Published As

Publication number Publication date
EP0667156B1 (de) 1997-09-10
ES2106573T3 (es) 1997-11-01
TW316235B (de) 1997-09-21
KR950032169A (ko) 1995-12-20
EP0667156A1 (de) 1995-08-16
ATE157870T1 (de) 1997-09-15
US5538974A (en) 1996-07-23
DE69500660T2 (de) 1998-02-26
CA2141176A1 (en) 1995-07-28
CN1116928A (zh) 1996-02-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee