JP2911460B2 - 鼻又は目に使用する薬剤及びその製造法 - Google Patents

鼻又は目に使用する薬剤及びその製造法

Info

Publication number
JP2911460B2
JP2911460B2 JP63282639A JP28263988A JP2911460B2 JP 2911460 B2 JP2911460 B2 JP 2911460B2 JP 63282639 A JP63282639 A JP 63282639A JP 28263988 A JP28263988 A JP 28263988A JP 2911460 B2 JP2911460 B2 JP 2911460B2
Authority
JP
Japan
Prior art keywords
solution
azelastine
nasal
weight
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP63282639A
Other languages
English (en)
Japanese (ja)
Other versions
JPH01153639A (ja
Inventor
ヘルムート・ヘツチエ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asta Medica GmbH
Original Assignee
Asta Medica GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6340483&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2911460(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Asta Medica GmbH filed Critical Asta Medica GmbH
Publication of JPH01153639A publication Critical patent/JPH01153639A/ja
Application granted granted Critical
Publication of JP2911460B2 publication Critical patent/JP2911460B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP63282639A 1987-11-13 1988-11-10 鼻又は目に使用する薬剤及びその製造法 Expired - Lifetime JP2911460B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3738681 1987-11-13
DE3738681.6 1987-11-13

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP9359963A Division JP2956029B2 (ja) 1987-11-13 1997-12-26 点眼液剤
JP01995599A Division JP3207816B2 (ja) 1987-11-13 1999-01-28 点鼻液剤

Publications (2)

Publication Number Publication Date
JPH01153639A JPH01153639A (ja) 1989-06-15
JP2911460B2 true JP2911460B2 (ja) 1999-06-23

Family

ID=6340483

Family Applications (3)

Application Number Title Priority Date Filing Date
JP63282639A Expired - Lifetime JP2911460B2 (ja) 1987-11-13 1988-11-10 鼻又は目に使用する薬剤及びその製造法
JP9359963A Expired - Lifetime JP2956029B2 (ja) 1987-11-13 1997-12-26 点眼液剤
JP01995599A Expired - Lifetime JP3207816B2 (ja) 1987-11-13 1999-01-28 点鼻液剤

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP9359963A Expired - Lifetime JP2956029B2 (ja) 1987-11-13 1997-12-26 点眼液剤
JP01995599A Expired - Lifetime JP3207816B2 (ja) 1987-11-13 1999-01-28 点鼻液剤

Country Status (15)

Country Link
US (1) US5164194A (en:Method)
EP (1) EP0316633B1 (en:Method)
JP (3) JP2911460B2 (en:Method)
AT (1) ATE84968T1 (en:Method)
AU (1) AU613107B2 (en:Method)
CA (1) CA1319322C (en:Method)
DE (1) DE3877904D1 (en:Method)
DK (1) DK174928B1 (en:Method)
ES (1) ES2053678T3 (en:Method)
GR (1) GR3007202T3 (en:Method)
IE (1) IE61562B1 (en:Method)
NL (1) NL990011I1 (en:Method)
PT (1) PT88985B (en:Method)
YU (1) YU46988B (en:Method)
ZA (1) ZA888461B (en:Method)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2051726T3 (es) * 1987-01-17 1994-07-01 Asta Medica Ag Procedimiento para preparar productos inyectables que contienen azelastin y teofilina o azelastin y beta-mimeticos.
US5897858A (en) 1994-02-03 1999-04-27 Schering-Plough Healthcare Products, Inc. Nasal spray compositions exhibiting increased retention in the nasal cavity
US5976573A (en) 1996-07-03 1999-11-02 Rorer Pharmaceutical Products Inc. Aqueous-based pharmaceutical composition
JP2005281315A (ja) * 1997-07-02 2005-10-13 Aventis Pharmaceuticals Holdings Inc 水性薬理組成物
JP4138910B2 (ja) * 1997-07-02 2008-08-27 帝國製薬株式会社 経皮吸収性が良好で且つ皮膚刺激性の少ない塩酸アゼラスチン含有経皮製剤
US6080783A (en) * 1998-09-01 2000-06-27 Gum Tech International, Inc. Method and composition for delivering zinc to the nasal membrane
AU1054301A (en) * 1999-11-11 2001-06-06 Takeda Chemical Industries Ltd. Nasal drops containing fused pyridazine derivatives
US7833549B2 (en) * 2000-01-19 2010-11-16 Mannkind Corporation Dry powder formulations of antihistamine for nasal administration
DE10007203A1 (de) 2000-02-17 2001-08-23 Asta Medica Ag Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis
DE20009841U1 (de) * 2000-05-31 2001-10-25 Phyt-Immun GmbH, 66424 Homburg Nasensalbe auf Basis von Vaselin
JP3450805B2 (ja) * 2000-08-08 2003-09-29 わかもと製薬株式会社 水性医薬組成物
AU2002236781A1 (en) * 2001-01-18 2002-07-30 Medpointe Healthcare Inc. Treatment for snoring
TWI231759B (en) * 2001-06-27 2005-05-01 Alcon Inc Olopatadine formulations for topical administration
US7977376B2 (en) * 2001-06-27 2011-07-12 Novartis Ag Olopatadine formulations for topical nasal administration
US6641799B2 (en) 2002-04-03 2003-11-04 Nos Spray, Inc. Nasal spray for decongesting nasal passages
GB2389530B (en) * 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
PL373433A1 (en) 2002-08-30 2005-08-22 Altana Pharma Ag The use of the combination of ciclesonide and antihistamines for the treatment of allergic rhinitis
US8221771B2 (en) * 2003-08-05 2012-07-17 3M Innovative Properties Company Formulations containing an immune response modifier
US20070020299A1 (en) 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
CN1913882A (zh) * 2004-02-06 2007-02-14 Meda制药有限及两合公司 用抗胆碱能药单独或联合抗组胺药、磷酸二酯酶4抑制剂或皮质类固醇来治疗鼻炎
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
US8071073B2 (en) * 2004-11-24 2011-12-06 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
GB2423711B (en) 2005-10-24 2007-02-14 Fortune Apex Dev Ltd Method for preparing a pharmaceutical composition with enhanced mucoadhesion
US7378082B1 (en) * 2007-11-05 2008-05-27 Inspire Pharmaceuticals, Inc. Method for treating allergic rhinitis without adverse effects
ES2493641T3 (es) * 2007-06-28 2014-09-12 Cydex Pharmaceuticals, Inc. Administración nasal de soluciones acuosas de corticosteroides
US12370352B2 (en) 2007-06-28 2025-07-29 Cydex Pharmaceuticals, Inc. Nasal and ophthalmic delivery of aqueous corticosteroid solutions
RU2010129833A (ru) * 2007-12-21 2012-01-27 Шеринг-Плау Хельскер Продактс, Инк. (Us) Повышение светоустойчивости оксиметазолина
WO2010025236A1 (en) * 2008-08-27 2010-03-04 Alexander Goldin Composition and method for treating colds
KR101261230B1 (ko) * 2010-11-29 2013-05-07 한림제약(주) 모메타손 푸로에이트 및 아젤라스틴 염산염을 포함하는 비내 투여용 약학 조성물
JP6545148B2 (ja) 2013-03-13 2019-07-17 フラットリー ディスカバリー ラブ，エルエルシー ピリダジノン化合物及び嚢胞性線維症の治療のための方法
EP3061501A1 (en) 2015-02-27 2016-08-31 Rottapharm Ltd. Composition for the treatment of acne
EP3117825A1 (en) 2015-07-16 2017-01-18 Rottapharm S.p.A. Oral formulation comprising berberine and morus alba extract
FI3934653T3 (fi) * 2020-05-29 2023-03-01 CEBINA GmbH Atselastiini antiviraalisessa hoidossa
JP2023530166A (ja) 2020-06-15 2023-07-13 アルケム・ラボラトリーズ・リミテッド アルカフタジンとコルチコステロイドの組み合わせ
JP2024512121A (ja) 2021-04-01 2024-03-18 アルケム・ラボラトリーズ・リミテッド アルカフタジンを含む鼻用組成物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6034925B2 (ja) 2015-07-07 2016-11-30 株式会社ブリヂストン 接着剤組成物、接着剤被覆繊維、ゴム物品及び空気入りタイヤ

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US158564A (en) * 1875-01-12 Improvement in medicine-droppers
US2119643A (en) * 1934-11-07 1938-06-07 Mendl Viktor Pressure-operated diffuser of toilet-liquids
US2136940A (en) * 1936-07-02 1938-11-15 Aromel Corp Atomizer
US2457024A (en) * 1945-02-13 1948-12-21 Arp Claus Collapsible tube holder
US2995308A (en) * 1958-09-23 1961-08-08 American Home Prod Jet stream dispenser
CH572914A5 (en:Method) * 1971-01-22 1976-02-27 Asta Werke Ag Chem Fab
US3813384A (en) * 1972-01-17 1974-05-28 Asta Werke Ag Chem Fab Basically substituted benzyl phthalazone derivatives,acid salts thereof and process for the production thereof
DE3530793A1 (de) * 1984-09-14 1986-03-27 Asta-Werke Ag Chemische Fabrik, 4800 Bielefeld Substituierte benzylphthalazinon-derivate
ATE49205T1 (de) * 1984-09-14 1990-01-15 Asta Pharma Ag Substituierte benzylphthalazinon-derivate.
US4769369A (en) * 1986-11-14 1988-09-06 Pennwalt Corporation Anti-allergy 1(2H)-phthalazinones

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6034925B2 (ja) 2015-07-07 2016-11-30 株式会社ブリヂストン 接着剤組成物、接着剤被覆繊維、ゴム物品及び空気入りタイヤ

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
南山堂 医学大辞典 １９７９，３．１発行 ｐ１４６５

Also Published As

Publication number Publication date
JPH10182464A (ja) 1998-07-07
DK630188D0 (da) 1988-11-11
NL990011I1 (nl) 1999-07-01
JPH01153639A (ja) 1989-06-15
JP3207816B2 (ja) 2001-09-10
AU2506388A (en) 1989-05-18
EP0316633B1 (de) 1993-01-27
CA1319322C (en) 1993-06-22
JP2956029B2 (ja) 1999-10-04
EP0316633A1 (de) 1989-05-24
IE61562B1 (en) 1994-11-16
YU209288A (en) 1990-04-30
IE883403L (en) 1989-05-13
AU613107B2 (en) 1991-07-25
JPH11349484A (ja) 1999-12-21
DE3877904D1 (de) 1993-03-11
GR3007202T3 (en:Method) 1993-07-30
DK630188A (da) 1989-05-14
ATE84968T1 (de) 1993-02-15
ZA888461B (en) 1989-08-30
US5164194A (en) 1992-11-17
PT88985B (pt) 1993-01-29
PT88985A (pt) 1988-12-01
YU46988B (sh) 1994-09-09
ES2053678T3 (es) 1994-08-01
DK174928B1 (da) 2004-03-01

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