JP2620789B2 - 活性物質の経口投与製剤 - Google Patents

活性物質の経口投与製剤

Info

Publication number
JP2620789B2
JP2620789B2 JP62223202A JP22320287A JP2620789B2 JP 2620789 B2 JP2620789 B2 JP 2620789B2 JP 62223202 A JP62223202 A JP 62223202A JP 22320287 A JP22320287 A JP 22320287A JP 2620789 B2 JP2620789 B2 JP 2620789B2
Authority
JP
Japan
Prior art keywords
active substance
substance
oral administration
preparation
containing layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP62223202A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6377816A (ja
Inventor
ヴォルフガング・シュミット
Original Assignee
デジティン アルツナイミッテル ゲーエムベーハー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by デジティン アルツナイミッテル ゲーエムベーハー filed Critical デジティン アルツナイミッテル ゲーエムベーハー
Publication of JPS6377816A publication Critical patent/JPS6377816A/ja
Application granted granted Critical
Publication of JP2620789B2 publication Critical patent/JP2620789B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
JP62223202A 1986-09-09 1987-09-08 活性物質の経口投与製剤 Expired - Lifetime JP2620789B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19863630603 DE3630603A1 (de) 1986-09-09 1986-09-09 Darreichungs- und dosierungsform fuer arzneimittelwirkstoffe, reagentien oder dergleichen sowie verfahren zu deren herstellung
DE3630603.7 1986-09-09

Publications (2)

Publication Number Publication Date
JPS6377816A JPS6377816A (ja) 1988-04-08
JP2620789B2 true JP2620789B2 (ja) 1997-06-18

Family

ID=6309183

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62223202A Expired - Lifetime JP2620789B2 (ja) 1986-09-09 1987-09-08 活性物質の経口投与製剤

Country Status (9)

Country Link
US (1) US4925670A (OSRAM)
EP (1) EP0259749B1 (OSRAM)
JP (1) JP2620789B2 (OSRAM)
AT (1) ATE66142T1 (OSRAM)
AU (1) AU601478B2 (OSRAM)
CA (1) CA1313497C (OSRAM)
DE (2) DE3630603A1 (OSRAM)
ES (1) ES2023649B3 (OSRAM)
GR (1) GR3003083T3 (OSRAM)

Families Citing this family (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3803482A1 (de) * 1988-02-05 1989-08-17 Lohmann Therapie Syst Lts Schwimmfaehiges orales therapeutisches system
US5354551A (en) * 1989-10-14 1994-10-11 Desitin Arzneimittel Gmbh Oral and dental hygiene preparation
WO1991005540A1 (de) * 1989-10-14 1991-05-02 Desitin Arzneimittel Gmbh Mund- und zahnpflegemittel
AT397345B (de) * 1990-04-04 1994-03-25 Chemiefaser Lenzing Ag Pharmazeutisches präparat mit verzögerter wirkstofffreisetzung auf basis von hemicellulosen
DE4018247A1 (de) * 1990-06-07 1991-12-12 Lohmann Therapie Syst Lts Herstellungsverfahren fuer schnellzerfallende folienfoermige darreichungsformen
DE4419824A1 (de) * 1994-06-07 1995-12-14 Lohmann Therapie Syst Lts Volumen-expandierbares, als Wirkstoffträger insbesondere zur oralen Anwendung geeignete flächige Anwendungsform
DE4419818C2 (de) * 1994-06-07 1998-10-22 Lohmann Therapie Syst Lts Wirkstoffträger zur kontrollierten Freisetzung von Wirkstoffen im Gastrointestinaltrakt mit verzögerter Pyloruspassage und Verfahren zur Herstellung desselben
DE19503338C2 (de) * 1995-02-02 1998-07-30 Lohmann Therapie Syst Lts Arzneiform zur Abgabe von Kollagenase an Wunden und Verfahren zu ihrer Herstellung und ihre Verwendung
DE19503336C2 (de) * 1995-02-02 1998-07-30 Lohmann Therapie Syst Lts Arzneiform zur Abgabe von Wirkstoffen an Wunden, Verfahren zu ihrer Herstellung und ihre Verwendung
DE19549506C2 (de) * 1995-03-07 1998-07-30 Richard Prof Dr Sueverkruep Darreichungsform zur äußerlichen Applikation und Verfahren zur Herstellung derselben
CZ352197A3 (cs) 1995-05-09 1998-04-15 Colorcon Limited Způsob elektrostatického potahování a zařízení k jeho provádění
US7008668B2 (en) * 1995-05-09 2006-03-07 Phoqus Pharmaceuticals Limited Powder coating composition for electrostatic coating of pharmaceutical substrates
DE19646392A1 (de) * 1996-11-11 1998-05-14 Lohmann Therapie Syst Lts Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht
GB9623634D0 (en) 1996-11-13 1997-01-08 Bpsi Holdings Inc Method and apparatus for the coating of substrates for pharmaceutical use
DE19652257A1 (de) 1996-12-16 1998-06-18 Lohmann Therapie Syst Lts Einzeln dosierte, bei Kontakt mit Flüssigkeit schnell zerfallende, wirkstoff- und insbesondere aromastoffhaltige, folienförmige Darreichnungsform
US6096328A (en) * 1997-06-06 2000-08-01 The Procter & Gamble Company Delivery system for an oral care substance using a strip of material having low flexural stiffness
US20020018754A1 (en) * 1999-03-15 2002-02-14 Paul Albert Sagel Shapes for tooth whitening strips
DE19736520A1 (de) * 1997-08-22 1999-02-25 Lohmann Therapie Syst Lts Kennzeichnung für klebende flächenförmige dermale und transdermale therapeutische Darreichungsformen unter Verwendung eines klebenden Plfasters als Informationsträger, sowie Verfahren zu seiner Herstellung
DE19745208A1 (de) * 1997-10-13 1999-04-15 Labtec Gmbh Mundfilm
US6596298B2 (en) 1998-09-25 2003-07-22 Warner-Lambert Company Fast dissolving orally comsumable films
US20030211136A1 (en) * 1998-09-25 2003-11-13 Neema Kulkarni Fast dissolving orally consumable films containing a sweetener
US20030206942A1 (en) * 1998-09-25 2003-11-06 Neema Kulkarni Fast dissolving orally consumable films containing an antitussive and a mucosa coating agent
DE19856101A1 (de) * 1998-12-04 2000-06-08 Labtec Gmbh Mundhöhlen-Matrixpflaster
DE19900645C2 (de) * 1999-01-11 2003-03-20 Deotexis Inc Transdermales therapeutisches System
US6800329B2 (en) * 1999-02-12 2004-10-05 Lts Lohmann Therapie-Systeme Ag Method for producing film-type dosage
US6231957B1 (en) 1999-05-06 2001-05-15 Horst G. Zerbe Rapidly disintegrating flavor wafer for flavor enrichment
USRE42126E1 (en) 1999-07-02 2011-02-08 The Procter & Gamble Company Delivery system for oral care compositions comprising organosiloxane resins using a removable backing strip
US6806017B2 (en) 1999-12-17 2004-10-19 Phoqus Limited Electrostatic application of powder material to solid dosage forms
GB0002305D0 (en) 2000-02-01 2000-03-22 Phoqus Limited Power material for electrostatic application
US7067116B1 (en) 2000-03-23 2006-06-27 Warner-Lambert Company Llc Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1
DE10025644A1 (de) * 2000-05-24 2001-12-06 Lohmann Therapie Syst Lts Schmales bandförmiges transdermales therapeutisches System zur Applikation von Wirkstoffen direkt über dem arteriellen oder venösen Gefäßsystem
US6702894B2 (en) 2001-10-24 2004-03-09 Hewlett-Packard Development Company, L.P. Fluid ejection cartridge and system for dispensing a bioactive substance
US6962715B2 (en) * 2001-10-24 2005-11-08 Hewlett-Packard Development Company, L.P. Method and dosage form for dispensing a bioactive substance
US6660292B2 (en) * 2001-06-19 2003-12-09 Hf Flavoring Technology Llp Rapidly disintegrating flavored film for precooked foods
US6419903B1 (en) * 2001-08-20 2002-07-16 Colgate Palmolive Company Breath freshening film
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US7910641B2 (en) 2001-10-12 2011-03-22 Monosol Rx, Llc PH modulated films for delivery of actives
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20070154527A1 (en) * 2001-10-12 2007-07-05 Monosoirx, Llc Topical film compositions for delivery of actives
US7425292B2 (en) 2001-10-12 2008-09-16 Monosol Rx, Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US8663687B2 (en) 2001-10-12 2014-03-04 Monosol Rx, Llc Film compositions for delivery of actives
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US20060039958A1 (en) * 2003-05-28 2006-02-23 Monosolrx, Llc. Multi-layer films having uniform content
US20100021526A1 (en) * 2001-10-12 2010-01-28 Monosol Rx, Llc Ph modulated films for delivery of actives
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
EP2351557B1 (en) * 2001-10-12 2019-04-17 Aquestive Therapeutics, Inc. Thin film with non-self-aggregating uniform heterogeneity, process for ther production and drug delivery systems made therefrom
US7666337B2 (en) 2002-04-11 2010-02-23 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
AU2003235716A1 (en) 2002-01-17 2003-07-30 Lts Lohmann Therapie-Systeme Ag Method for neutralizing or recycling carrier materials for film-like coatings
US7232500B2 (en) 2002-01-25 2007-06-19 Lts Lohmann Therapie-Systeme Ag Method and device for producing products in web form
DE10213772A1 (de) * 2002-03-27 2003-10-09 Gruenenthal Gmbh Zusammenhängende Einheit aus vereinzelbaren transdermalen therapeutischen Systemen
US8017150B2 (en) 2002-04-11 2011-09-13 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
FR2840221B1 (fr) * 2002-06-04 2006-01-13 Backert Marie Elisabeth Cuine Film polymerique contenant des "actifs" destines a etre liberes dans un liquide
US6937455B2 (en) * 2002-07-03 2005-08-30 Kronos Advanced Technologies, Inc. Spark management method and device
US7053565B2 (en) 2002-07-03 2006-05-30 Kronos Advanced Technologies, Inc. Electrostatic fluid accelerator for and a method of controlling fluid flow
CN1747656B (zh) 2002-07-22 2011-05-04 莫诺索尔克斯有限公司 速溶剂型的包装和分配
US20040120991A1 (en) * 2002-09-07 2004-06-24 Mars Incorporated Edible films having distinct regions
US8524200B2 (en) 2002-09-11 2013-09-03 The Procter & Gamble Company Tooth whitening products
WO2004050008A1 (ja) * 2002-12-02 2004-06-17 Kyukyu Pharmaceutical Co., Ltd. 積層フィルム状可食性口腔内投与剤の製造方法およびその圧着装置
US20040137152A1 (en) * 2003-01-09 2004-07-15 Parriott Donald Ward Method and apparatus for producing a uniform film on a substrate
EP1587504B1 (en) * 2003-01-30 2012-04-18 MonoSolRX, LLC Process for the manufacture of a thin film comprising heat sensitive actives
DE20305447U1 (de) 2003-04-04 2003-06-12 Klocke Verpackungs-Service GmbH, 76356 Weingarten Pharmazeutisches Produkt mit einem Träger
WO2004096193A1 (en) * 2003-05-02 2004-11-11 Warner-Lambert Company Llc Fast dissolving orally consumable films containing a modified starch for improved heat and moisture resistance
EP1663178A1 (en) * 2003-05-28 2006-06-07 MonoSolRX, LLC Films based on poly(ethylene oxide), and drug delivery systems made thereof
GB2420297B (en) * 2003-06-18 2006-11-15 Phoqus Pharmaceuticals Ltd Method and apparatus for the application of powder material to substrates
GB0330171D0 (en) * 2003-12-30 2004-02-04 Phoqus Pharmaceuticals Ltd Method and apparatus for the application of powder material to substrates
US20050186256A1 (en) * 2004-02-20 2005-08-25 Dihel Deborah L. Dissolvable film comprising an active ingredient and method of manufacture
GB0407312D0 (en) 2004-03-31 2004-05-05 Phoqus Pharmaceuticals Ltd Method and apparatus for the application of powder material to substrates
US7399482B1 (en) 2004-05-07 2008-07-15 Christine Horner Biernacki Thin film medication device and kit
US20060104910A1 (en) * 2004-11-15 2006-05-18 Keith Lerner Over dosage indicating medicated film strip
US9198897B2 (en) 2005-01-19 2015-12-01 Neurohealing Pharmaceuticals, Inc. Methods and compositions for decreasing saliva production
WO2006107390A2 (en) 2005-04-04 2006-10-12 Kronos Advanced Technologies, Inc. An electrostatic fluid accelerator for and method of controlling a fluid flow
DE202005014347U1 (de) * 2005-09-09 2007-01-18 Grünenthal GmbH Applikationssystem für ein wirkstoffhaltiges Pflaster und Wirkstoffabgaberegulierungsmittel
WO2007056066A2 (en) 2005-11-04 2007-05-18 Lifescience Plus, Inc. Bioabsorbable hemostatic gauze
EP1986602A2 (en) * 2006-01-20 2008-11-05 MonoSol Rx LLC Film bandage for mucosal administration of actives
JP2009523672A (ja) * 2006-01-20 2009-06-25 モノソル アールエックス リミテッド ライアビリティ カンパニー フィルムライニングを施した、包装体およびその製法
CA2664097A1 (en) * 2006-09-20 2008-03-27 Monosol Rx, Llc Edible water-soluble film containing a foam reducing flavoring agent
CN101534799A (zh) * 2006-09-29 2009-09-16 莫诺索尔克斯有限公司 膜埋入式包装及其制备方法
JP5590891B2 (ja) * 2007-12-06 2014-09-17 リンテック株式会社 可食性フィルム
US8475832B2 (en) 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions
US20110136815A1 (en) * 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
EP2579844B1 (en) 2010-06-10 2016-02-24 Midatech Ltd. Nanoparticle film delivery systems
KR101802553B1 (ko) * 2010-09-23 2017-11-28 모노졸 알엑스, 엘엘씨 제약 생성물을 패키지 표면 상에 직접적으로 형성시키는 방법 및 시스템
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
EP2578088A1 (en) 2011-10-06 2013-04-10 Nestec S.A. Edible web comprising microorganisms
CA2888199C (en) 2012-10-17 2019-06-25 The Procter & Gamble Company Strip for the delivery of an oral care active and methods for applying oral care actives
US9545376B2 (en) 2013-01-23 2017-01-17 Arx, Llc Production of unit dose constructs
KR20190005199A (ko) 2016-05-05 2019-01-15 어퀘스티브 테라퓨틱스, 아이엔씨. 강화된 전달 에프네프린 조성물
US12427121B2 (en) 2016-05-05 2025-09-30 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
US12433850B2 (en) 2016-05-05 2025-10-07 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine and prodrug compositions
WO2018080337A1 (en) * 2016-10-27 2018-05-03 Kondakov Sergey Emilevich Finished pharmaceutical form with individual medicine dosing capability (embodiments) and methods of its production and use
RU2674692C2 (ru) * 2016-10-27 2018-12-12 Общество с ограниченной ответственностью "Инжиниринговый сервис и консалтинг" Готовая лекарственная форма с возможностью индивидуального дозирования лекарственного средства, способ ее производства и применения
US12465564B2 (en) 2021-10-25 2025-11-11 Aquestive Therapeutics, Inc. Oral and nasal compositions and methods of treatment

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE637363A (OSRAM) *
FR1382158A (fr) * 1963-09-12 1964-12-18 Ciba Geigy Nouveaux médicaments et procédé pour leur préparation
GB1434042A (en) * 1973-07-05 1976-04-28 Ciba Geigy Ag Chemical compositions
JPS5319345B2 (OSRAM) * 1974-05-17 1978-06-20
US4136162A (en) * 1974-07-05 1979-01-23 Schering Aktiengesellschaft Medicament carriers in the form of film having active substance incorporated therein
IN142428B (OSRAM) * 1974-07-05 1977-07-09 Schering Ag
DE2449865B2 (de) * 1974-10-17 1981-06-19 Schering Ag Berlin Und Bergkamen, 1000 Berlin Folienförmiges Arzneimittel
CH624846A5 (en) * 1975-12-15 1981-08-31 Hoffmann La Roche Solid pharmaceutical unit dose form and process and apparatus for producing it
US4197289A (en) * 1975-12-15 1980-04-08 Hoffmann-La Roche Inc. Novel dosage forms
DE2746414A1 (de) * 1977-10-15 1979-04-26 Gerlach Eduard Chem Fab Mittel zum dosieren von stoffen und verfahren zu seiner herstellung
GB2022999A (en) * 1978-06-17 1979-12-28 Culpitt & Son Ltd G Paper compositions incorporating medicaments
DE2922522A1 (de) * 1979-06-01 1980-12-04 Dudzik Joachim Tablette
JPS58134019A (ja) * 1982-02-05 1983-08-10 Ono Pharmaceut Co Ltd プロスタグランジン含有持続放出型三層状フイルム製剤及びその製造方法
US4451260A (en) * 1982-03-26 1984-05-29 Minnesota Mining And Manufacturing Company Sustained release oral medicinal delivery device
DE3676626D1 (de) * 1985-10-09 1991-02-07 Desitin Arzneimittel Gmbh Verfahren zur herstellung einer darreichungs- und dosierungsform fuer arzneimittel-wirkstoffe, reagentien oder andere wirkstoffe.

Also Published As

Publication number Publication date
JPS6377816A (ja) 1988-04-08
GR3003083T3 (en) 1993-02-17
EP0259749A1 (de) 1988-03-16
AU601478B2 (en) 1990-09-13
AU7792987A (en) 1988-03-17
CA1313497C (en) 1993-02-09
EP0259749B1 (de) 1991-08-14
US4925670A (en) 1990-05-15
ATE66142T1 (de) 1991-08-15
DE3630603A1 (de) 1988-03-10
ES2023649B3 (es) 1992-02-01
DE3772136D1 (de) 1991-09-19
DE3630603C2 (OSRAM) 1989-06-22

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