JP2541420B2 - ３−ブテン酸誘導体及びその製法 - Google Patents

３−ブテン酸誘導体及びその製法

Info

Publication number
JP2541420B2
JP2541420B2 JP4119480A JP11948092A JP2541420B2 JP 2541420 B2 JP2541420 B2 JP 2541420B2 JP 4119480 A JP4119480 A JP 4119480A JP 11948092 A JP11948092 A JP 11948092A JP 2541420 B2 JP2541420 B2 JP 2541420B2
Authority
JP
Japan
Prior art keywords
group
formula
lower alkoxy
compound
butenoic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP4119480A
Other languages
English (en)
Japanese (ja)
Other versions
JPH05279308A (ja
Inventor
為雄 岩▲崎▼
喬 西谷
章雄 大谷
正徳 稲益
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Priority to JP4119480A priority Critical patent/JP2541420B2/ja
Priority to AU35250/93A priority patent/AU658271B2/en
Priority to US08/033,804 priority patent/US5514815A/en
Priority to CA 2092017 priority patent/CA2092017A1/en
Priority to IL105124A priority patent/IL105124A0/xx
Priority to TW082102204A priority patent/TW225515B/zh
Priority to EP93104977A priority patent/EP0563798B1/en
Priority to AT93104977T priority patent/ATE154344T1/de
Priority to ES93104977T priority patent/ES2104985T3/es
Priority to DK93104977.9T priority patent/DK0563798T3/da
Priority to DE69311419T priority patent/DE69311419T2/de
Priority to KR1019930004851A priority patent/KR930019609A/ko
Priority to CN 93103522 priority patent/CN1078720A/zh
Priority to FI931346A priority patent/FI931346L/fi
Publication of JPH05279308A publication Critical patent/JPH05279308A/ja
Priority to US08/436,564 priority patent/US5639789A/en
Application granted granted Critical
Publication of JP2541420B2 publication Critical patent/JP2541420B2/ja
Priority to GR970401446T priority patent/GR3023808T3/el
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C243/30—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
    • C07C243/32—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP4119480A 1992-03-26 1992-03-26 ３−ブテン酸誘導体及びその製法 Expired - Lifetime JP2541420B2 (ja)

Priority Applications (16)

Application Number Priority Date Filing Date Title
JP4119480A JP2541420B2 (ja) 1992-03-26 1992-03-26 ３−ブテン酸誘導体及びその製法
AU35250/93A AU658271B2 (en) 1992-03-26 1993-03-17 Butadiene derivatives and process for preparing the same
US08/033,804 US5514815A (en) 1992-03-26 1993-03-18 Succinimide derivatives and process for preparing the same
CA 2092017 CA2092017A1 (en) 1992-03-26 1993-03-19 Butadiene derivatives and process for preparing the same
IL105124A IL105124A0 (en) 1992-03-26 1993-03-22 Butadiene derivatives,their preparation and pharmaceutical compositions containing them
TW082102204A TW225515B (enrdf_load_stackoverflow) 1992-03-26 1993-03-24
DK93104977.9T DK0563798T3 (da) 1992-03-26 1993-03-25 Butadienderivater og fremgangsmåder til fremstilling deraf
ES93104977T ES2104985T3 (es) 1992-03-26 1993-03-25 Derivados de butadieno, su preparacion y utilizacion como agente antitrombotico.
EP93104977A EP0563798B1 (en) 1992-03-26 1993-03-25 Butadiene derivatives, their preparation and use as an antithrombotic agent
DE69311419T DE69311419T2 (de) 1992-03-26 1993-03-25 Butadienderivate, ihre Herstellung und Verwendung als antithrombotisches Mittel
AT93104977T ATE154344T1 (de) 1992-03-26 1993-03-25 Butadienderivate, ihre herstellung und verwendung als antithrombotisches mittel
CN 93103522 CN1078720A (zh) 1992-03-26 1993-03-26 丁二烯衍生物及其制备方法
KR1019930004851A KR930019609A (ko) 1992-03-26 1993-03-26 부타디엔 유도체 및 그의 제법
FI931346A FI931346L (fi) 1992-03-26 1993-03-26 Butadienderivat och foerfarande foer deras framstaellning
US08/436,564 US5639789A (en) 1992-03-26 1995-05-08 Butadiene derivatives and process for using the same
GR970401446T GR3023808T3 (en) 1992-03-26 1997-06-19 Butadiene derivatives, their preparation and use as an antithrombotic agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4119480A JP2541420B2 (ja) 1992-03-26 1992-03-26 ３−ブテン酸誘導体及びその製法

Publications (2)

Publication Number Publication Date
JPH05279308A JPH05279308A (ja) 1993-10-26
JP2541420B2 true JP2541420B2 (ja) 1996-10-09

Family

ID=14762339

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4119480A Expired - Lifetime JP2541420B2 (ja) 1992-03-26 1992-03-26 ３−ブテン酸誘導体及びその製法

Country Status (3)

Country Link
JP (1) JP2541420B2 (enrdf_load_stackoverflow)
KR (1) KR930019609A (enrdf_load_stackoverflow)
TW (1) TW225515B (enrdf_load_stackoverflow)

Also Published As

Publication number Publication date
KR930019609A (ko) 1993-10-18
JPH05279308A (ja) 1993-10-26
TW225515B (enrdf_load_stackoverflow) 1994-06-21

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