JP2025504908A - サイトカイン関連腫瘍浸潤リンパ球組成物及び方法 - Google Patents

サイトカイン関連腫瘍浸潤リンパ球組成物及び方法 Download PDF

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JP2025504908A
JP2025504908A JP2024544388A JP2024544388A JP2025504908A JP 2025504908 A JP2025504908 A JP 2025504908A JP 2024544388 A JP2024544388 A JP 2024544388A JP 2024544388 A JP2024544388 A JP 2024544388A JP 2025504908 A JP2025504908 A JP 2025504908A
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JP2025504908A5 (enExample
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ジー． フォーグト，フレデリック
ファーディス，マリア
シャルティエ－クルト，セシル
キュバス，ラファエル
ジャン，ヨンリャン
パトリック インナマラト，フォース，パスクアーレ
ギルバート，ネイサン
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アイオバンス バイオセラピューティクス，インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4231—Cytokines
    • A61K40/4234—Interleukins [IL]
    • A—HUMAN NECESSITIES
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    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
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    • C12N2501/2302—Interleukin-2 (IL-2)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
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    • C12N2502/30—Coculture with; Conditioned medium produced by tumour cells
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Plant Pathology (AREA)
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2024544388A 2022-01-28 2023-01-27 サイトカイン関連腫瘍浸潤リンパ球組成物及び方法 Pending JP2025504908A (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US202263304498P 2022-01-28 2022-01-28
US63/304,498 2022-01-28
US202263356933P 2022-06-29 2022-06-29
US63/356,933 2022-06-29
US202263394267P 2022-08-01 2022-08-01
US63/394,267 2022-08-01
US202263382493P 2022-11-04 2022-11-04
US63/382,493 2022-11-04
US202263429114P 2022-11-30 2022-11-30
US63/429,114 2022-11-30
PCT/US2023/061474 WO2023147488A1 (en) 2022-01-28 2023-01-27 Cytokine associated tumor infiltrating lymphocytes compositions and methods

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JP2025504908A true JP2025504908A (ja) 2025-02-19
JP2025504908A5 JP2025504908A5 (enExample) 2026-02-03

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US (1) US20250099588A1 (enExample)
EP (1) EP4469065A1 (enExample)
JP (1) JP2025504908A (enExample)
CA (1) CA3243419A1 (enExample)
TW (1) TW202346573A (enExample)
WO (1) WO2023147488A1 (enExample)

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TW202540200A (zh) 2023-12-01 2025-10-16 美商基利科學股份有限公司 抗ｆａｐ－ｌｉｇｈｔ融合蛋白及其用途
WO2025259871A1 (en) 2024-06-14 2025-12-18 Gilead Sciences, Inc. Anti-ccr8 antibodies and uses thereof

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