JP2025185070A5 - - Google Patents
Info
- Publication number
- JP2025185070A5 JP2025185070A5 JP2025166543A JP2025166543A JP2025185070A5 JP 2025185070 A5 JP2025185070 A5 JP 2025185070A5 JP 2025166543 A JP2025166543 A JP 2025166543A JP 2025166543 A JP2025166543 A JP 2025166543A JP 2025185070 A5 JP2025185070 A5 JP 2025185070A5
- Authority
- JP
- Japan
- Prior art keywords
- rnai agent
- nucleotides
- composition
- sense strand
- cytidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762529132P | 2017-07-06 | 2017-07-06 | |
| US62/529,132 | 2017-07-06 | ||
| US201862631683P | 2018-02-17 | 2018-02-17 | |
| US62/631,683 | 2018-02-17 | ||
| US201862679549P | 2018-06-01 | 2018-06-01 | |
| US62/679,549 | 2018-06-01 | ||
| JP2019572571A JP2020526192A (ja) | 2017-07-06 | 2018-07-05 | アルファ−ＥＮａＣの発現を阻害するためのＲＮＡｉ剤、および使用方法 |
| PCT/US2018/040874 WO2019010274A1 (en) | 2017-07-06 | 2018-07-05 | RNAI AGENTS OF INHIBITION OF ALPHA-ENAC GENE EXPRESSION AND METHODS OF USE |
| JP2023146393A JP2023158192A (ja) | 2017-07-06 | 2023-09-08 | アルファ－ＥＮａＣの発現を阻害するためのＲＮＡｉ剤、および使用方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023146393A Division JP2023158192A (ja) | 2017-07-06 | 2023-09-08 | アルファ－ＥＮａＣの発現を阻害するためのＲＮＡｉ剤、および使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025185070A JP2025185070A (ja) | 2025-12-18 |
| JP2025185070A5 true JP2025185070A5 (OSRAM) | 2026-01-30 |
Family
ID=64904123
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019572571A Withdrawn JP2020526192A (ja) | 2017-07-06 | 2018-07-05 | アルファ−ＥＮａＣの発現を阻害するためのＲＮＡｉ剤、および使用方法 |
| JP2023146393A Pending JP2023158192A (ja) | 2017-07-06 | 2023-09-08 | アルファ－ＥＮａＣの発現を阻害するためのＲＮＡｉ剤、および使用方法 |
| JP2025166543A Pending JP2025185070A (ja) | 2017-07-06 | 2025-10-02 | アルファ－ＥＮａＣの発現を阻害するためのＲＮＡｉ剤、および使用方法 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019572571A Withdrawn JP2020526192A (ja) | 2017-07-06 | 2018-07-05 | アルファ−ＥＮａＣの発現を阻害するためのＲＮＡｉ剤、および使用方法 |
| JP2023146393A Pending JP2023158192A (ja) | 2017-07-06 | 2023-09-08 | アルファ－ＥＮａＣの発現を阻害するためのＲＮＡｉ剤、および使用方法 |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US10590416B2 (OSRAM) |
| EP (1) | EP3649240A4 (OSRAM) |
| JP (3) | JP2020526192A (OSRAM) |
| KR (1) | KR20200024793A (OSRAM) |
| CN (2) | CN119662650A (OSRAM) |
| AU (1) | AU2018297262A1 (OSRAM) |
| BR (1) | BR112019023650A2 (OSRAM) |
| CA (1) | CA3061752A1 (OSRAM) |
| CL (1) | CL2020000019A1 (OSRAM) |
| CO (1) | CO2019014671A2 (OSRAM) |
| CR (1) | CR20190572A (OSRAM) |
| EC (1) | ECSP20000655A (OSRAM) |
| IL (1) | IL271843A (OSRAM) |
| JO (1) | JOP20190263A1 (OSRAM) |
| MX (1) | MX2019014800A (OSRAM) |
| PE (1) | PE20200746A1 (OSRAM) |
| PH (1) | PH12019502660A1 (OSRAM) |
| TN (1) | TN2019000308A1 (OSRAM) |
| TW (1) | TW201919654A (OSRAM) |
| UY (1) | UY37800A (OSRAM) |
| WO (1) | WO2019010274A1 (OSRAM) |
| ZA (1) | ZA202100643B (OSRAM) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20200024793A (ko) * | 2017-07-06 | 2020-03-09 | 애로우헤드 파마슈티컬스 인코포레이티드 | 알파-ENaC의 발현을 억제하기 위한 RNAi 작용제 및 사용 방법 |
| CA3089276A1 (en) * | 2018-02-17 | 2019-08-22 | Arrowhead Pharmaceuticals, Inc. | Trialkyne linking agents and methods of use |
| US12065458B2 (en) | 2018-02-17 | 2024-08-20 | Arrowhead Pharmaceuticals, Inc. | Trialkyne linking agents and methods of use |
| TW202130809A (zh) * | 2019-10-29 | 2021-08-16 | 美商愛羅海德製藥公司 | 用於抑制β-ENaC表現之RNAi藥劑、其組合物及使用方法 |
| AU2021342155A1 (en) * | 2020-09-11 | 2023-04-13 | Arrowhead Pharmaceuticals, Inc. | RNAi agents for inhibiting expression of DUX4, compositions thereof, and methods of use |
| AU2022422864A1 (en) | 2021-12-21 | 2024-07-04 | Suzhou Ribo Life Science Co., Ltd. | Nucleic acid, composition and conjugate containing nucleic acid, preparation method therefor and use thereof |
| EP4562147A1 (en) * | 2022-07-27 | 2025-06-04 | E-Therapeutics plc | Nucleic acid compounds |
| EP4562148A1 (en) * | 2022-07-27 | 2025-06-04 | E-Therapeutics plc | Nucleic acid compounds |
| WO2024188174A1 (zh) | 2023-03-10 | 2024-09-19 | 苏州瑞博生物技术股份有限公司 | 一种药物组合物及其用途 |
| KR20260026026A (ko) * | 2023-06-13 | 2026-02-25 | 투오지에 바이오텍 (상하이) 컴퍼니 리미티드 | MMP7을 표적으로 하는 siRNA, siRNA 접합체 및 이의 의학적 용도 |
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| AU742598B2 (en) | 1997-03-11 | 2002-01-10 | Yale University | Method to diagnose and treat pathological conditions resulting from deficient ion transport such as pseudohypoaldosteronism type-1 |
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| US5976849A (en) | 1998-02-05 | 1999-11-02 | Zeneca Limited | Human E3 ubiquitin protein ligase |
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| KR100872437B1 (ko) | 2000-12-01 | 2008-12-05 | 막스-플랑크-게젤샤프트 츄어 푀르더룽 데어 비쎈샤프텐 에.파우. | Ｒｎａ 간섭을 매개하는 작은 ｒｎａ 분자 |
| JP2005512510A (ja) | 2001-05-16 | 2005-05-12 | ノバルティス アクチエンゲゼルシャフト | 予後および治療標的として乳癌で発現される遺伝子 |
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| JOP20160211B1 (ar) * | 2015-10-01 | 2021-08-17 | Arrowhead Pharmaceuticals Inc | تراكيب وأساليب لتثبيط تعبير جيني للـ lpa |
| CN109952376B (zh) | 2016-11-01 | 2023-09-05 | 箭头药业股份有限公司 | αvβ6整联蛋白配体及其应用 |
| KR20200024793A (ko) * | 2017-07-06 | 2020-03-09 | 애로우헤드 파마슈티컬스 인코포레이티드 | 알파-ENaC의 발현을 억제하기 위한 RNAi 작용제 및 사용 방법 |
| KR102762143B1 (ko) * | 2017-11-01 | 2025-02-07 | 애로우헤드 파마슈티컬스 인코포레이티드 | 인테그린 리간드 및 그의 용도 |
| CA3089276A1 (en) * | 2018-02-17 | 2019-08-22 | Arrowhead Pharmaceuticals, Inc. | Trialkyne linking agents and methods of use |
-
2018
- 2018-07-05 KR KR1020197038728A patent/KR20200024793A/ko not_active Ceased
- 2018-07-05 AU AU2018297262A patent/AU2018297262A1/en not_active Abandoned
- 2018-07-05 CR CR20190572A patent/CR20190572A/es unknown
- 2018-07-05 BR BR112019023650-3A patent/BR112019023650A2/pt not_active Application Discontinuation
- 2018-07-05 CA CA3061752A patent/CA3061752A1/en active Pending
- 2018-07-05 EP EP18828259.4A patent/EP3649240A4/en active Pending
- 2018-07-05 CN CN202411877733.3A patent/CN119662650A/zh active Pending
- 2018-07-05 CN CN201880045293.1A patent/CN110832077B/zh active Active
- 2018-07-05 US US16/028,006 patent/US10590416B2/en active Active
- 2018-07-05 MX MX2019014800A patent/MX2019014800A/es unknown
- 2018-07-05 TN TNP/2019/000308A patent/TN2019000308A1/en unknown
- 2018-07-05 WO PCT/US2018/040874 patent/WO2019010274A1/en not_active Ceased
- 2018-07-05 PE PE2019002542A patent/PE20200746A1/es unknown
- 2018-07-05 JP JP2019572571A patent/JP2020526192A/ja not_active Withdrawn
- 2018-07-06 TW TW107123550A patent/TW201919654A/zh unknown
- 2018-07-06 UY UY0001037800A patent/UY37800A/es not_active Application Discontinuation
-
2019
- 2019-01-06 JO JOP/2019/0263A patent/JOP20190263A1/ar unknown
- 2019-11-25 PH PH12019502660A patent/PH12019502660A1/en unknown
- 2019-12-24 CO CONC2019/0014671A patent/CO2019014671A2/es unknown
-
2020
- 2020-01-03 CL CL2020000019A patent/CL2020000019A1/es unknown
- 2020-01-06 IL IL271843A patent/IL271843A/en unknown
- 2020-01-06 EC ECSENADI2020655A patent/ECSP20000655A/es unknown
- 2020-01-31 US US16/778,582 patent/US11214802B2/en active Active
-
2021
- 2021-01-29 ZA ZA2021/00643A patent/ZA202100643B/en unknown
- 2021-11-29 US US17/536,754 patent/US20220090077A1/en not_active Abandoned
-
2023
- 2023-09-08 JP JP2023146393A patent/JP2023158192A/ja active Pending
-
2025
- 2025-10-02 JP JP2025166543A patent/JP2025185070A/ja active Pending
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