JP2025041812A5 - - Google Patents

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Publication number
JP2025041812A5
JP2025041812A5 JP2024226961A JP2024226961A JP2025041812A5 JP 2025041812 A5 JP2025041812 A5 JP 2025041812A5 JP 2024226961 A JP2024226961 A JP 2024226961A JP 2024226961 A JP2024226961 A JP 2024226961A JP 2025041812 A5 JP2025041812 A5 JP 2025041812A5
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JP
Japan
Prior art keywords
ligand
flexible linker
protease cleavage
cleavage sequence
antibody
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Pending
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JP2024226961A
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English (en)
Japanese (ja)
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JP2025041812A (ja
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Priority claimed from PCT/JP2017/042570 external-priority patent/WO2018097308A1/ja
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Publication of JP2025041812A publication Critical patent/JP2025041812A/ja
Publication of JP2025041812A5 publication Critical patent/JP2025041812A5/ja
Pending legal-status Critical Current

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JP2024226961A 2016-11-28 2024-12-24 リガンド結合活性が調整可能なリガンド結合分子 Pending JP2025041812A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2016229882 2016-11-28
JP2016229882 2016-11-28
PCT/JP2017/042570 WO2018097308A1 (ja) 2016-11-28 2017-11-28 リガンド結合活性が調整可能なリガンド結合分子
JP2018553014A JP7626577B2 (ja) 2016-11-28 2017-11-28 リガンド結合活性が調整可能なリガンド結合分子
JP2023038624A JP7671794B2 (ja) 2016-11-28 2023-03-13 リガンド結合活性が調整可能なリガンド結合分子

Related Parent Applications (1)

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JP2023038624A Division JP7671794B2 (ja) 2016-11-28 2023-03-13 リガンド結合活性が調整可能なリガンド結合分子

Publications (2)

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JP2025041812A JP2025041812A (ja) 2025-03-26
JP2025041812A5 true JP2025041812A5 (https=) 2025-11-07

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ID=62195875

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JP2018553014A Active JP7626577B2 (ja) 2016-11-28 2017-11-28 リガンド結合活性が調整可能なリガンド結合分子
JP2023038624A Active JP7671794B2 (ja) 2016-11-28 2023-03-13 リガンド結合活性が調整可能なリガンド結合分子
JP2024226961A Pending JP2025041812A (ja) 2016-11-28 2024-12-24 リガンド結合活性が調整可能なリガンド結合分子

Family Applications Before (2)

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JP2018553014A Active JP7626577B2 (ja) 2016-11-28 2017-11-28 リガンド結合活性が調整可能なリガンド結合分子
JP2023038624A Active JP7671794B2 (ja) 2016-11-28 2023-03-13 リガンド結合活性が調整可能なリガンド結合分子

Country Status (12)

Country Link
US (2) US12060654B2 (https=)
EP (1) EP3546480A4 (https=)
JP (3) JP7626577B2 (https=)
KR (2) KR102533814B1 (https=)
CN (1) CN110214151A (https=)
AU (1) AU2017364818C1 (https=)
BR (1) BR112019008265A2 (https=)
CA (1) CA3039316A1 (https=)
IL (1) IL266827B2 (https=)
MX (3) MX2019005947A (https=)
TW (2) TW202235438A (https=)
WO (1) WO2018097308A1 (https=)

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WO2018097308A1 (ja) 2016-11-28 2018-05-31 中外製薬株式会社 リガンド結合活性が調整可能なリガンド結合分子
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CN114127277A (zh) * 2019-06-05 2022-03-01 中外制药株式会社 蛋白酶底物和包含蛋白酶切割序列的多肽
JPWO2020246563A1 (https=) 2019-06-05 2020-12-10
KR20220020879A (ko) 2019-06-12 2022-02-21 에스크진 파마, 아이엔씨. 새로운 il-15 프로드럭 및 이를 사용하는 방법
EP4021927A1 (en) * 2019-08-29 2022-07-06 Antagonis Biotherapeutics GmbH T-cell mobilizing cxcl10 mutant with increased glycosaminoglycan binding affinity
WO2021142471A1 (en) 2020-01-11 2021-07-15 AskGene Pharma, Inc. Novel masked cytokines and methods of use thereof
CN115943210A (zh) * 2020-01-20 2023-04-07 中外制药株式会社 配体结合融合蛋白
EP3889183A1 (en) * 2020-04-01 2021-10-06 Pierre Fabre Medicament A protein complex comprising an immunocytokine
JP2024527582A (ja) * 2021-07-19 2024-07-25 中外製薬株式会社 融合ポリペプチドを用いるプロテアーゼ媒介性の標的特異的サイトカイン送達
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JP2024527582A (ja) 2021-07-19 2024-07-25 中外製薬株式会社 融合ポリペプチドを用いるプロテアーゼ媒介性の標的特異的サイトカイン送達

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