JP2024537043A5 - - Google Patents
Info
- Publication number
- JP2024537043A5 JP2024537043A5 JP2024519270A JP2024519270A JP2024537043A5 JP 2024537043 A5 JP2024537043 A5 JP 2024537043A5 JP 2024519270 A JP2024519270 A JP 2024519270A JP 2024519270 A JP2024519270 A JP 2024519270A JP 2024537043 A5 JP2024537043 A5 JP 2024537043A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- pharmaceutically acceptable
- modified oligonucleotide
- aqueous solution
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163253933P | 2021-10-08 | 2021-10-08 | |
| US63/253,933 | 2021-10-08 | ||
| PCT/US2022/077766 WO2023060237A1 (en) | 2021-10-08 | 2022-10-07 | Methods and compositions for treatment of polycystic kidney disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024537043A JP2024537043A (ja) | 2024-10-10 |
| JP2024537043A5 true JP2024537043A5 (https=) | 2026-04-27 |
Family
ID=84246040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024519270A Pending JP2024537043A (ja) | 2021-10-08 | 2022-10-07 | 多嚢胞性腎疾患の治療のための方法及び組成物 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20240294913A1 (https=) |
| EP (1) | EP4413132A1 (https=) |
| JP (1) | JP2024537043A (https=) |
| KR (1) | KR20240073028A (https=) |
| CN (1) | CN118103510A (https=) |
| AR (1) | AR127325A1 (https=) |
| AU (1) | AU2022361062A1 (https=) |
| CA (1) | CA3234547A1 (https=) |
| CL (1) | CL2024000990A1 (https=) |
| CO (1) | CO2024004227A2 (https=) |
| IL (1) | IL311734A (https=) |
| MX (1) | MX2024003529A (https=) |
| TW (1) | TW202320808A (https=) |
| WO (1) | WO2023060237A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023060237A1 (en) | 2021-10-08 | 2023-04-13 | Regulus Therapeutics Inc. | Methods and compositions for treatment of polycystic kidney disease |
| KR20260005213A (ko) * | 2023-04-12 | 2026-01-09 | 레굴루스 테라퓨틱스 인크 | 다낭성 신장 질환 치료를 위한 변형 올리고뉴클레오타이드 |
| EP4680746A1 (en) * | 2023-06-16 | 2026-01-21 | Pyc Therapeutics Limited | Compositions and methods for treatment of kidney disease |
| WO2025193584A1 (en) * | 2024-03-11 | 2025-09-18 | Regulus Therapeutics Inc. | Compound for use in methods for treatment of polycystic kidney disease |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7683036B2 (en) | 2003-07-31 | 2010-03-23 | Regulus Therapeutics Inc. | Oligomeric compounds and compositions for use in modulation of small non-coding RNAs |
| NZ549535A (en) | 2004-03-17 | 2010-11-26 | Novartis Ag | Use of aliskiren for treating renal and other disorders |
| BRPI0509979A (pt) | 2004-04-20 | 2007-10-16 | Genaco Biomedical Products Inc | método para detectar ncrna |
| EP1791567B1 (en) | 2004-08-10 | 2015-07-29 | Alnylam Pharmaceuticals Inc. | Chemically modified oligonucleotides |
| US20070213292A1 (en) * | 2005-08-10 | 2007-09-13 | The Rockefeller University | Chemically modified oligonucleotides for use in modulating micro RNA and uses thereof |
| US20070092882A1 (en) * | 2005-10-21 | 2007-04-26 | Hui Wang | Analysis of microRNA |
| GB0523659D0 (en) | 2005-11-21 | 2005-12-28 | Novartis Ag | Organic compounds |
| EP2007888A2 (en) | 2006-04-03 | 2008-12-31 | Santaris Pharma A/S | Pharmaceutical composition comprising anti-mirna antisense oligonucleotides |
| WO2007126150A1 (ja) | 2006-04-27 | 2007-11-08 | National University Corporation Nagoya University | 癌の新規治療用組成物 |
| US20120283411A9 (en) | 2006-06-29 | 2012-11-08 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| CA2927045A1 (en) | 2006-10-03 | 2008-04-10 | Muthiah Manoharan | Lipid containing formulations |
| WO2008131191A2 (en) | 2007-04-20 | 2008-10-30 | Amgen Inc. | Nucleic acids hybridizable to micro rna and precursors thereof |
| EP2714904B1 (en) | 2007-06-14 | 2017-04-12 | Mirx Therapeutics ApS | Oligonucleotides for modulation of target rna activity |
| EP2623599B1 (en) | 2007-10-04 | 2019-01-02 | Roche Innovation Center Copenhagen A/S | Micromirs |
| US8211867B2 (en) * | 2007-10-29 | 2012-07-03 | Regulus Therapeutics Inc. | Targeting microRNAs for the treatment of liver cancer |
| CA2717792A1 (en) * | 2008-03-07 | 2009-09-11 | Santaris Pharma A/S | Pharmaceutical compositions for treatment of microrna related diseases |
| WO2009143403A1 (en) | 2008-05-23 | 2009-11-26 | Targacept, Inc. | Combination therapy for the management hypertension |
| AU2010319555A1 (en) | 2009-11-11 | 2012-06-14 | Sanford-Burnham Medical Research Institute | Method for generation and regulation of iPS cells and compositions thereof |
| US20130236453A1 (en) | 2012-03-12 | 2013-09-12 | The Ohio State University | Methods and Compositions for Modulating Acute Graft-versus-Host Disease using miR-155 Specific Inhibitors |
| WO2013165320A1 (en) | 2012-05-04 | 2013-11-07 | Agency For Science, Technology And Research | Treating cancer by increasing expression of socs6 |
| SG10201803157XA (en) * | 2013-05-01 | 2018-05-30 | Regulus Therapeutics Inc | Microrna compounds and methods for modulating mir-122 |
| US10660890B2 (en) | 2013-10-24 | 2020-05-26 | National Institutes Of Health (Nih), U.S. Dept. Of Health And Human Services (Dhhs), U.S. Government Nih Division Of Extramural Inventions And Technology Resources (Deitr) | Treatment of polycystic diseases with an HDAC6 inhibitor |
| JP2017511694A (ja) | 2014-02-12 | 2017-04-27 | トーマス・ジェファーソン・ユニバーシティ | マイクロｒｎａ阻害剤を使用するための組成物および方法 |
| JP6929269B2 (ja) | 2015-08-26 | 2021-09-01 | レグルス セラピューティクス インコーポレイテッド | 多発性嚢胞腎の処置のための方法 |
| WO2018047148A1 (en) | 2016-09-12 | 2018-03-15 | Novartis Ag | Compounds for the inhibition of mirna |
| WO2018106566A1 (en) | 2016-12-05 | 2018-06-14 | Regulus Therapeutics Inc. | Modified oligonucleotides for treatment of polycystic kidney disease |
| AU2017372695B2 (en) | 2016-12-05 | 2023-07-20 | Regulus Therapeutics Inc. | Methods for treatment of polycystic kidney disease |
| US20200392503A1 (en) | 2016-12-05 | 2020-12-17 | Regulus Therapeutics Inc. | Methods and compositions for treatment of polycystic kidney disease |
| US20220380767A1 (en) | 2016-12-05 | 2022-12-01 | Regulus Therapeutics Inc. | Methods and compositions for treatment of polycystic kidney disease |
| EP4098746A4 (en) | 2020-01-31 | 2024-01-24 | National University Corporation Tokai National Higher Education and Research System | SINGLE-STRANDED POLYNUCLEOTIDE |
| WO2023060237A1 (en) | 2021-10-08 | 2023-04-13 | Regulus Therapeutics Inc. | Methods and compositions for treatment of polycystic kidney disease |
| JP2024535445A (ja) | 2021-10-08 | 2024-09-30 | レグルス セラピューティクス インコーポレイテッド | オフターゲット効果を回避するための方法及び組成物 |
| KR20260005213A (ko) | 2023-04-12 | 2026-01-09 | 레굴루스 테라퓨틱스 인크 | 다낭성 신장 질환 치료를 위한 변형 올리고뉴클레오타이드 |
-
2022
- 2022-10-07 WO PCT/US2022/077766 patent/WO2023060237A1/en not_active Ceased
- 2022-10-07 TW TW111138235A patent/TW202320808A/zh unknown
- 2022-10-07 AU AU2022361062A patent/AU2022361062A1/en active Pending
- 2022-10-07 CA CA3234547A patent/CA3234547A1/en active Pending
- 2022-10-07 JP JP2024519270A patent/JP2024537043A/ja active Pending
- 2022-10-07 EP EP22800530.2A patent/EP4413132A1/en active Pending
- 2022-10-07 IL IL311734A patent/IL311734A/en unknown
- 2022-10-07 MX MX2024003529A patent/MX2024003529A/es unknown
- 2022-10-07 KR KR1020247010026A patent/KR20240073028A/ko active Pending
- 2022-10-07 CN CN202280066728.7A patent/CN118103510A/zh active Pending
- 2022-10-11 AR ARP220102755A patent/AR127325A1/es unknown
-
2024
- 2024-03-20 US US18/610,891 patent/US20240294913A1/en active Pending
- 2024-04-03 CL CL2024000990A patent/CL2024000990A1/es unknown
- 2024-04-05 CO CONC2024/0004227A patent/CO2024004227A2/es unknown
-
2025
- 2025-02-12 US US19/052,052 patent/US12559750B2/en active Active
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