JP2024534781A5 - - Google Patents

Info

Publication number
JP2024534781A5
JP2024534781A5 JP2024508978A JP2024508978A JP2024534781A5 JP 2024534781 A5 JP2024534781 A5 JP 2024534781A5 JP 2024508978 A JP2024508978 A JP 2024508978A JP 2024508978 A JP2024508978 A JP 2024508978A JP 2024534781 A5 JP2024534781 A5 JP 2024534781A5
Authority
JP
Japan
Prior art keywords
alkyl
group
membered
compound according
haloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024508978A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024534781A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/075045 external-priority patent/WO2023023532A2/en
Publication of JP2024534781A publication Critical patent/JP2024534781A/ja
Publication of JP2024534781A5 publication Critical patent/JP2024534781A5/ja
Pending legal-status Critical Current

Links

JP2024508978A 2021-08-18 2022-08-17 Ccr6阻害剤としてのアリールスルホニル(ヒドロキシ)ピペリジン Pending JP2024534781A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163234271P 2021-08-18 2021-08-18
US63/234,271 2021-08-18
US202263354906P 2022-06-23 2022-06-23
US63/354,906 2022-06-23
PCT/US2022/075045 WO2023023532A2 (en) 2021-08-18 2022-08-17 Aryl sulfonyl (hydroxy) piperidines as ccr6 inhibitors

Publications (2)

Publication Number Publication Date
JP2024534781A JP2024534781A (ja) 2024-09-26
JP2024534781A5 true JP2024534781A5 (enExample) 2025-08-22

Family

ID=85239796

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024508978A Pending JP2024534781A (ja) 2021-08-18 2022-08-17 Ccr6阻害剤としてのアリールスルホニル(ヒドロキシ)ピペリジン

Country Status (15)

Country Link
US (1) US12018016B2 (enExample)
EP (1) EP4387609A4 (enExample)
JP (1) JP2024534781A (enExample)
KR (1) KR20240049280A (enExample)
AU (1) AU2022328699A1 (enExample)
CA (1) CA3228553A1 (enExample)
CL (1) CL2024000486A1 (enExample)
CO (1) CO2024002818A2 (enExample)
CR (1) CR20240136A (enExample)
IL (1) IL310368A (enExample)
JO (1) JOP20240029A1 (enExample)
MX (1) MX2024002139A (enExample)
PE (1) PE20240812A1 (enExample)
TW (1) TW202315614A (enExample)
WO (1) WO2023023532A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL305262A (en) 2021-03-10 2023-10-01 Jnana Therapeutics Inc Small molecule inhibitors of mammalian SLC6A19 function
HUE070709T2 (hu) 2021-08-18 2025-06-28 Nurix Therapeutics Inc Interleukin-1 receptorhoz kapcsolódó kinázok kétfunkciós lebontói és terápiás alkalmazásuk
MX2024002173A (es) 2021-08-18 2024-03-26 Chemocentryx Inc Compuestos de arilsulfonilo como inhibidores de ccr6.
TW202435874A (zh) * 2023-02-06 2024-09-16 瑞士商赫孚孟拉羅股份公司 新穎化合物
WO2025252631A1 (en) * 2024-06-04 2025-12-11 F. Hoffmann-La Roche Ag Hydroxyl compounds targeting the ccr6 receptor
WO2025252626A1 (en) * 2024-06-04 2025-12-11 F. Hoffmann-La Roche Ag Hydroxyl compounds targeting the ccr6 receptor
WO2025252653A1 (en) * 2024-06-04 2025-12-11 F. Hoffmann-La Roche Ag Hydroxyl compounds targeting the ccr6 receptor

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
LU86084A1 (fr) 1985-09-20 1987-04-02 Faco Sa Apparei de massage electrique
US5102417A (en) 1985-11-07 1992-04-07 Expandable Grafts Partnership Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
US4800882A (en) 1987-03-13 1989-01-31 Cook Incorporated Endovascular stent and delivery system
US4886062A (en) 1987-10-19 1989-12-12 Medtronic, Inc. Intravascular radially expandable stent and method of implant
WO1990013332A1 (en) 1989-05-11 1990-11-15 Cedars-Sinai Medical Center Stent with sustained drug delivery
EP0470246B1 (en) 1990-02-28 1995-06-28 Medtronic, Inc. Intralumenal drug eluting prosthesis
US5419760A (en) 1993-01-08 1995-05-30 Pdt Systems, Inc. Medicament dispensing stent for prevention of restenosis of a blood vessel
US5429634A (en) 1993-09-09 1995-07-04 Pdt Systems Biogenic implant for drug delivery and method
US6774278B1 (en) 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
US5833651A (en) 1996-11-08 1998-11-10 Medtronic, Inc. Therapeutic intraluminal stents
US6294192B1 (en) 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
EP1193256A1 (en) * 2000-09-27 2002-04-03 Applied Research Systems ARS Holding N.V. Pharmaceutically active benzsulfonamide derivatives as inhibitors of JNK proteins
JP2004526733A (ja) 2001-03-20 2004-09-02 メルク エンド カムパニー インコーポレーテッド 強力な細胞接着阻害剤としての置換n−アリールスルホニル−プロリン誘導体
AR036366A1 (es) 2001-08-29 2004-09-01 Schering Corp Derivados de piperidina utiles como antagonistas de ccr5, composiciones farmaceuticas, el uso de dichos derivados para la fabricación de un medicamento y un kit
AR037352A1 (es) 2001-11-14 2004-11-03 Schering Corp Compuestos ligandos de los receptores de los cannabinoides, una composicion farmaceutica , y el uso de dichos compuestos para la manufactura de medicamentos
CA2476583C (en) 2002-03-13 2011-07-05 Kristof Van Emelen Aminocarbonyl-derivatives as novel inhibitors of histone deacetylase
WO2003076401A1 (en) 2002-03-13 2003-09-18 Janssen Pharmaceutica N.V. Sulfonylamino-derivatives as novel inhibitors of histone deacetylase
CN100396679C (zh) 2002-03-13 2008-06-25 詹森药业有限公司 用作组蛋白脱乙酰化酶抑制剂的哌嗪基、哌啶基和吗啉基衍生物
JP4648628B2 (ja) 2002-03-13 2011-03-09 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ヒストンデアセチラーゼの新規な阻害剤としてのカルボニルアミノ誘導体
US6770729B2 (en) 2002-09-30 2004-08-03 Medtronic Minimed, Inc. Polymer compositions containing bioactive agents and methods for their use
WO2004033632A2 (en) 2002-10-04 2004-04-22 Bristol-Myers Squibb Company Hydantoin derivatives as inhibitors of matrix metalloproteinases and/or tnf-alpha converting enzyme (tace)
SE0302116D0 (sv) 2003-07-21 2003-07-21 Astrazeneca Ab Novel compounds
CN100393718C (zh) 2003-08-12 2008-06-11 霍夫曼-拉罗奇有限公司 作为npy拮抗剂的噻唑衍生物
JP2005119987A (ja) 2003-10-15 2005-05-12 Ajinomoto Co Inc アシルスルホンアミド誘導体
EP2316458A1 (en) 2004-09-20 2011-05-04 Xenon Pharmaceuticals Inc. Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase
RU2405770C2 (ru) 2005-09-27 2010-12-10 Сионоги Энд Ко., Лтд. Производное сульфонамида, обладающее антагонистической активностью в отношении рецептора pgd2
US20090143396A1 (en) 2005-10-12 2009-06-04 Malecha James W Sulfonyl-Substituted Aryl Compounds as Modulators of Peroxisome Proliferator Activated Receptors
AR059355A1 (es) 2006-02-07 2008-03-26 Wyeth Corp Inhibidores de 11-beta hsd1
US8071779B2 (en) 2006-12-18 2011-12-06 Inspire Pharmaceuticals, Inc. Cytoskeletal active rho kinase inhibitor compounds, composition and use
WO2009158587A1 (en) 2008-06-26 2009-12-30 Inspire Pharmaceuticals, Inc. Method for treating pulmonary diseases using rho kinase inhibitor compounds
EP2400969A4 (en) 2008-12-04 2012-05-16 Inspire Pharmaceuticals Inc METHOD FOR TREATING PULMONARY DISEASES USING RHO KINASE INHIBITORY COMPOUNDS
CN102264737A (zh) 2008-12-23 2011-11-30 雅培制药有限公司 抗病毒化合物
JP2013047189A (ja) 2009-12-25 2013-03-07 Kyorin Pharmaceutical Co Ltd 新規パラバン酸誘導体及びそれらを有効成分とする医薬
EP2523664A4 (en) 2010-01-13 2013-06-26 Tempero Pharmaceuticals Inc COMPOUNDS AND METHODS
WO2012012282A1 (en) 2010-07-19 2012-01-26 Inspire Pharmaceuticals, Inc. Bifunctional rho kinase inhibitor compounds, composition and use
EP2597953A4 (en) 2010-07-27 2013-12-25 Inspire Pharmaceuticals Inc METHOD FOR THE TREATMENT OF EYE DISEASES USING KINASE-INHIBITOR COMPOUNDS IN PRODRUG FORMS
WO2013157021A1 (en) 2012-04-20 2013-10-24 Advinus Therapeutics Limited Bicyclic compounds, compositions and medicinal applications thereof
US20150376198A1 (en) 2013-02-18 2015-12-31 The Scripps Research Institute Modulators of vasopressin receptors with therapeutic potential
WO2015058163A2 (en) 2013-10-18 2015-04-23 Syros Pharmaceuticals, Inc. Inhibitors of cyclin-dependent kinase 7 (cdk7)
JP6383418B2 (ja) 2013-11-27 2018-08-29 ジェネンテック, インコーポレイテッド 置換ベンズアミド及びその使用方法
CN105960237B (zh) 2013-12-02 2020-03-31 凯莫森特里克斯股份有限公司 Ccr6化合物
LT3105218T (lt) 2014-02-13 2019-12-10 Incyte Corp Ciklopropilaminai kaip lsd1 inhibitoriai
US9974784B2 (en) 2015-01-21 2018-05-22 The Texas A&M University System Inhibitors of activin-like receptor kinases
WO2016161268A1 (en) * 2015-04-01 2016-10-06 Enanta Pharmaceuticals, Inc. Hepatitis b antviral agents
PE20180572A1 (es) 2015-06-18 2018-04-04 Cephalon Inc Derivados de piperidina 1,4-sustituidos
AU2016283105C1 (en) 2015-06-26 2023-02-02 Dana-Farber Cancer Institute, Inc. 4,6-pyrimidinylene derivatives and uses thereof
WO2017070320A1 (en) 2015-10-21 2017-04-27 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Phenyl indole allosteric inhibitors of p97 atpase
US10766858B2 (en) 2016-03-30 2020-09-08 Genentech, Inc. Substituted benzamides and methods of use thereof
RU2018145734A (ru) 2016-06-08 2020-07-14 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Химические соединения в качестве ингибиторов atf4 пути
JP7258748B2 (ja) 2016-11-22 2023-04-17 ダナ-ファーバー キャンサー インスティテュート, インコーポレイテッド サイクリン依存性キナーゼ12(cdk12)の阻害剤およびその使用
WO2018106818A1 (en) 2016-12-07 2018-06-14 Kura Oncology, Inc. Methods of promoting beta cell proliferation
WO2019204505A2 (en) 2018-04-18 2019-10-24 Theras, Inc. K-ras modulators with a vinyl sulfonamide moiety
WO2019204442A1 (en) 2018-04-18 2019-10-24 Theras, Inc. K-ras modulators with a cyanoacrylamide moiety
SG11202013175SA (en) 2018-06-29 2021-01-28 Kinnate Biopharma Inc Inhibitors of cyclin-dependent kinases
EP3820500A4 (en) 2018-07-13 2022-04-13 Teqla Therapeutics, Inc. USE OF BCL6 INHIBITORS TO TREAT AUTOIMMUNE DISEASES
EP4061341A4 (en) 2019-11-22 2024-04-10 The Regents of the University of California CASPASE6 INHIBITORS AND USES THEREOF
CN113135896B (zh) 2020-01-18 2024-12-06 正大天晴药业集团股份有限公司 作为ret抑制剂的甲基吡唑类衍生物
WO2022173849A1 (en) * 2021-02-10 2022-08-18 Qilu Regor Therapeutics Inc. (hetero)arylamino-cyclohexyl-sulfonyl derivatives as ccr6 inhibitors
MX2024002173A (es) * 2021-08-18 2024-03-26 Chemocentryx Inc Compuestos de arilsulfonilo como inhibidores de ccr6.

Similar Documents

Publication Publication Date Title
JP2023515618A5 (enExample)
JP2025508192A5 (enExample)
JP2010513519A5 (enExample)
JP2018507238A5 (enExample)
JP2021513967A5 (enExample)
JP2022537140A5 (enExample)
JP2019535838A5 (enExample)
JP2022552445A5 (enExample)
JP2017504595A5 (enExample)
JP2011513476A5 (enExample)
RU2019105719A (ru) Антагонисты tlr7/8 и их применение
JP2013523803A5 (enExample)
JP2024538694A5 (enExample)
JP2017511357A5 (enExample)
JP2015502387A5 (enExample)
JP2007504160A5 (enExample)
JP2016509047A5 (enExample)
JP2009527501A5 (enExample)
BR112012023649B1 (pt) Método para produção de cristais de forma ii de monoidrato de n1 -(5-cloropiridin-2-il)-n2 -((1s,2r,4s)-4-[(dimetilamino) carbonil]-2-{[(5-metil-4,5,6,7-tetrahidrotiazol[5,4-c]piridin-2-il) carbonil] amino}ciclohexil)etanodiamida p-toluenossulfonato
AU2017330618A1 (en) TRPV4 antagonists
RU2020115596A (ru) ПИРИМИДИНОВЫЕ СОЕДИНЕНИЯ В КАЧЕСТВЕ ИНГИБИТОРОВ TBK/IKKε И ИХ ПРИМЕНЕНИЯ
JP2021522262A5 (enExample)
JP2024517016A5 (enExample)
JP2023528421A5 (enExample)
JP2022533939A5 (enExample)