JP2023515618A5 - - Google Patents
Info
- Publication number
- JP2023515618A5 JP2023515618A5 JP2022552206A JP2022552206A JP2023515618A5 JP 2023515618 A5 JP2023515618 A5 JP 2023515618A5 JP 2022552206 A JP2022552206 A JP 2022552206A JP 2022552206 A JP2022552206 A JP 2022552206A JP 2023515618 A5 JP2023515618 A5 JP 2023515618A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- compound
- alkyl
- independently
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062983537P | 2020-02-28 | 2020-02-28 | |
| US62/983,537 | 2020-02-28 | ||
| US202063007134P | 2020-04-08 | 2020-04-08 | |
| US63/007,134 | 2020-04-08 | ||
| US202063040474P | 2020-06-17 | 2020-06-17 | |
| US63/040,474 | 2020-06-17 | ||
| US202063072781P | 2020-08-31 | 2020-08-31 | |
| US63/072,781 | 2020-08-31 | ||
| US202063126491P | 2020-12-16 | 2020-12-16 | |
| US63/126,491 | 2020-12-16 | ||
| PCT/US2021/020173 WO2021174176A1 (en) | 2020-02-28 | 2021-02-28 | Pyridazine dervatives for modulating nucleic acid splicing |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023515618A JP2023515618A (ja) | 2023-04-13 |
| JP2023515618A5 true JP2023515618A5 (enExample) | 2025-08-06 |
| JP7901883B2 JP7901883B2 (ja) | 2026-08-07 |
Family
ID=75278334
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022552203A Pending JP2023515617A (ja) | 2020-02-28 | 2021-02-28 | 核酸スプライシングを調節するためのピリダジン誘導体 |
| JP2022552206A Active JP7901883B2 (ja) | 2020-02-28 | 2021-02-28 | 核酸スプライシングを調節するためのピリダジン誘導体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022552203A Pending JP2023515617A (ja) | 2020-02-28 | 2021-02-28 | 核酸スプライシングを調節するためのピリダジン誘導体 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20230365526A1 (enExample) |
| EP (2) | EP4110774A1 (enExample) |
| JP (2) | JP2023515617A (enExample) |
| KR (2) | KR20220157407A (enExample) |
| CN (2) | CN115551847A (enExample) |
| AU (3) | AU2021228286A1 (enExample) |
| BR (2) | BR112022017089A2 (enExample) |
| CA (2) | CA3169667A1 (enExample) |
| IL (2) | IL295954A (enExample) |
| MX (2) | MX2022010637A (enExample) |
| WO (2) | WO2021174176A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2020001425A (es) | 2017-08-04 | 2020-08-06 | Skyhawk Therapeutics Inc | Metodos y composiciones para modular el empalme. |
| WO2020163248A1 (en) | 2019-02-04 | 2020-08-13 | Skyhawk Therapeutics, Inc. | Methods and compositions for modulating splicing |
| KR102913697B1 (ko) * | 2019-02-05 | 2026-01-15 | 스카이호크 테라퓨틱스, 인코포레이티드 | 스플라이싱을 조절하는 방법 및 조성물 |
| WO2020163541A1 (en) | 2019-02-05 | 2020-08-13 | Skyhawk Therapeutics, Inc. | Methods and compositions for modulating splicing |
| JP7603594B2 (ja) | 2019-02-06 | 2024-12-20 | スカイホーク・セラピューティクス・インコーポレーテッド | スプライシングを調節するための方法および組成物 |
| KR102925385B1 (ko) | 2019-02-06 | 2026-02-11 | 스카이호크 테라퓨틱스, 인코포레이티드 | 스플라이싱을 조절하는 방법 및 조성물 |
| WO2021231571A1 (en) | 2020-05-13 | 2021-11-18 | Chdi Foundation, Inc. | Htt modulators for treating huntington's disease |
| US20250333397A1 (en) * | 2021-08-30 | 2025-10-30 | Remix Therapeutics Inc. | Compounds and methods for modulating splicing |
| WO2023034827A1 (en) | 2021-08-30 | 2023-03-09 | Remix Therapeutics Inc. | Compounds and methods for modulating splicing |
| EP4426702A1 (en) * | 2021-11-04 | 2024-09-11 | Skyhawk Therapeutics, Inc. | Condensed-pyrazine amine derivatives for treating sca3 |
| AU2022394333A1 (en) | 2021-11-17 | 2024-06-27 | Chdi Foundation, Inc. | HTT modulators for treating Huntington’s disease |
| EP4472969A4 (en) * | 2022-01-31 | 2025-12-24 | Novartis Ag | PROCESS FOR THE SYNTHESIS OF PYRAZOLYL DERIVATIVES USEFUL AS ANTICANCER AGENTS |
| WO2023185468A1 (zh) * | 2022-04-01 | 2023-10-05 | 浙江同源康医药股份有限公司 | 一类用作激酶抑制剂的化合物及其应用 |
| AU2023327925A1 (en) * | 2022-08-22 | 2025-02-20 | Redx Pharma Limited | Pyrido-pyrazoles as inhibitors of ddr's for the treatment of fibrotic disorders and cancer |
| WO2024182747A2 (en) * | 2023-03-01 | 2024-09-06 | Remix Therapeutics Inc. | Compounds and methods for modulating splicing |
| WO2025211457A1 (ja) * | 2024-04-05 | 2025-10-09 | 日本新薬株式会社 | Ｃｕｇリピートｒｎａとｍｂｎｌタンパクとの結合阻害化合物および医薬 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7160876B2 (en) * | 2003-12-22 | 2007-01-09 | Abbott Laboratories | Fused bicycloheterocycle substituted quinuclidine derivatives |
| EP3406252B1 (en) | 2012-02-10 | 2020-05-13 | PTC Therapeutics, Inc. | Compounds for treating spinal muscular atrophy |
| US8729263B2 (en) | 2012-08-13 | 2014-05-20 | Novartis Ag | 1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions |
| EP3029035B1 (en) * | 2013-07-31 | 2018-05-30 | Sumitomo Chemical Company, Limited | Tetrazolinone compound, and use thereof |
| MX381224B (es) * | 2014-10-31 | 2025-03-12 | Massachusetts Gen Hospital | Potentes moduladores de gamma-secretasa. |
| EP3256126B1 (en) * | 2015-02-09 | 2024-03-27 | F. Hoffmann-La Roche AG | Compounds for the treatment of cancer |
| EP3310169B1 (en) | 2015-05-30 | 2023-05-17 | PTC Therapeutics, Inc. | Methods for modulating rna splicing |
| CA3119019C (en) * | 2015-12-10 | 2024-06-11 | Ptc Therapeutics, Inc. | Compounds and methods for treating huntington's disease |
| JP2019535789A (ja) | 2016-11-28 | 2019-12-12 | ピーティーシー セラピューティクス，インコーポレーテッド | Ｒｎａスプライシングを調節する方法 |
| WO2018140578A1 (en) * | 2017-01-25 | 2018-08-02 | President And Fellows Of Harvard College | Non-fullerene solar panel acceptor compounds |
| CN111372611A (zh) * | 2017-06-14 | 2020-07-03 | Ptc医疗公司 | 修饰rna剪接的方法 |
| MX2020001425A (es) * | 2017-08-04 | 2020-08-06 | Skyhawk Therapeutics Inc | Metodos y composiciones para modular el empalme. |
| US20230152257A1 (en) | 2017-09-25 | 2023-05-18 | Skyhawk Therapeutics, Inc. | Methods and compositions for screening and identification of splicing |
| JP7270989B2 (ja) * | 2017-10-20 | 2023-05-11 | ヴァンダービルト ユニバーシティー | ムスカリン性アセチルコリン受容体ｍ４のアンタゴニスト |
| CA3090130A1 (en) * | 2018-02-02 | 2019-08-08 | Vanderbilt University | Antagonists of the muscarinic acetylcholine receptor m4 |
| JP2021521200A (ja) | 2018-04-10 | 2021-08-26 | スカイホーク・セラピューティクス・インコーポレーテッド | 癌の処置のための化合物 |
| TWI823932B (zh) * | 2018-05-11 | 2023-12-01 | 中國大陸商迪哲（江蘇）醫藥有限公司 | 三唑并嘧啶化合物及其在治療癌症中之用途 |
-
2021
- 2021-02-28 CA CA3169667A patent/CA3169667A1/en active Pending
- 2021-02-28 CN CN202180030690.3A patent/CN115551847A/zh active Pending
- 2021-02-28 IL IL295954A patent/IL295954A/en unknown
- 2021-02-28 BR BR112022017089A patent/BR112022017089A2/pt unknown
- 2021-02-28 KR KR1020227033652A patent/KR20220157407A/ko active Pending
- 2021-02-28 EP EP21715355.0A patent/EP4110774A1/en active Pending
- 2021-02-28 JP JP2022552203A patent/JP2023515617A/ja active Pending
- 2021-02-28 IL IL295953A patent/IL295953A/en unknown
- 2021-02-28 US US17/802,747 patent/US20230365526A1/en active Pending
- 2021-02-28 CA CA3169643A patent/CA3169643A1/en active Pending
- 2021-02-28 AU AU2021228286A patent/AU2021228286A1/en not_active Abandoned
- 2021-02-28 WO PCT/US2021/020173 patent/WO2021174176A1/en not_active Ceased
- 2021-02-28 US US17/802,702 patent/US20230140983A1/en active Pending
- 2021-02-28 CN CN202180031321.6A patent/CN115551843A/zh active Pending
- 2021-02-28 AU AU2021228288A patent/AU2021228288A1/en active Pending
- 2021-02-28 BR BR112022017107A patent/BR112022017107A2/pt unknown
- 2021-02-28 KR KR1020227033654A patent/KR20220158236A/ko active Pending
- 2021-02-28 MX MX2022010637A patent/MX2022010637A/es unknown
- 2021-02-28 WO PCT/US2021/020160 patent/WO2021174170A1/en not_active Ceased
- 2021-02-28 MX MX2022010634A patent/MX2022010634A/es unknown
- 2021-02-28 JP JP2022552206A patent/JP7901883B2/ja active Active
- 2021-02-28 EP EP21713826.2A patent/EP4110771A1/en active Pending
-
2024
- 2024-03-08 AU AU2024201568A patent/AU2024201568A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023515617A5 (enExample) | ||
| JP2023515621A5 (enExample) | ||
| JP2023515620A5 (enExample) | ||
| JP2023520924A5 (enExample) | ||
| JP2023520925A5 (enExample) | ||
| JP2023520916A5 (enExample) | ||
| JP2024520481A5 (enExample) | ||
| IL295953A (en) | Pyridazine derivatives regulate nucleic acid splicing | |
| IL295956A (en) | Heterocyclic amides and their use for modulating splicing | |
| JP2021534124A5 (enExample) | ||
| JP2023513680A5 (enExample) | ||
| JP2022512482A5 (enExample) | ||
| JP2023553835A5 (enExample) | ||
| JP2021522276A5 (enExample) | ||
| JP2022544714A5 (enExample) | ||
| JP2021523225A5 (enExample) | ||
| CN109790135B (zh) | 用于治疗或预防与痛风或高尿酸血症相关的症状的化合物、组合物和方法 | |
| JP2007508305A5 (enExample) | ||
| JP2016515096A (ja) | スルファモイル−アリールアミドおよびｂ型肝炎を処置するための医薬品としてのその使用 | |
| JP2007507542A5 (enExample) | ||
| JP2009544602A5 (enExample) | ||
| JP2012236838A5 (enExample) | ||
| JP2012507522A5 (enExample) | ||
| JP2018504437A5 (enExample) | ||
| JP2022553841A5 (enExample) |