JP2024534697A - 非環状脂質及びその使用方法 - Google Patents

非環状脂質及びその使用方法 Download PDF

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JP2024534697A
JP2024534697A JP2024540673A JP2024540673A JP2024534697A JP 2024534697 A JP2024534697 A JP 2024534697A JP 2024540673 A JP2024540673 A JP 2024540673A JP 2024540673 A JP2024540673 A JP 2024540673A JP 2024534697 A JP2024534697 A JP 2024534697A
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alkyl
optionally substituted
alkylenyl
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JP2024534697A5 (enExample
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ムスサミー ジャヤラマン，
スティーブン スカリー，
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レナゲード セラピューティクス マネージメント インコーポレイテッド
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JP2024540673A 2021-09-14 2022-09-14 非環状脂質及びその使用方法 Pending JP2024534697A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163244152P 2021-09-14 2021-09-14
US63/244,152 2021-09-14
US202163293284P 2021-12-23 2021-12-23
US63/293,284 2021-12-23
US202263336018P 2022-04-28 2022-04-28
US63/336,018 2022-04-28
PCT/US2022/076430 WO2023044343A1 (en) 2021-09-14 2022-09-14 Acyclic lipids and methods of use thereof

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JP2024534697A5 JP2024534697A5 (enExample) 2025-09-25

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EP (1) EP4402121A1 (enExample)
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CA (1) CA3231523A1 (enExample)
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EP4536293A1 (en) * 2022-06-10 2025-04-16 Renagade Therapeutics Management Inc. Nucleobase editing system and method of using same for modifying nucleic acid sequences
JP2025525569A (ja) 2022-07-18 2025-08-05 レナゲード セラピューティクス マネージメント インコーポレイテッド 遺伝子編集成分、システム、及び使用方法
CN117126071A (zh) * 2022-08-12 2023-11-28 上海蓝鹊生物医药有限公司 含氮链状化合物、其制备方法、包含其的组合物和应用
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WO2024140546A1 (zh) * 2022-12-26 2024-07-04 北京新合睿恩生物医疗科技有限公司 一种阳离子脂质化合物及制备方法和应用、mRNA递送系统
CN115677518B (zh) * 2023-01-05 2023-04-14 北京悦康科创医药科技股份有限公司 用于递送核酸的可电离阳离子脂质化合物和组合物及用途
CN116178193B (zh) * 2023-01-05 2023-07-28 北京悦康科创医药科技股份有限公司 高效低毒且稳定性表达的阳离子脂质化合物及其组合物
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WO2025000542A1 (en) * 2023-06-30 2025-01-02 Shanghai Vitalgen Biopharma Co., Ltd. Ionizable cationic lipid compounds for delivery of biologically active agents
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