JP2024534111A5 - - Google Patents
Info
- Publication number
- JP2024534111A5 JP2024534111A5 JP2024510689A JP2024510689A JP2024534111A5 JP 2024534111 A5 JP2024534111 A5 JP 2024534111A5 JP 2024510689 A JP2024510689 A JP 2024510689A JP 2024510689 A JP2024510689 A JP 2024510689A JP 2024534111 A5 JP2024534111 A5 JP 2024534111A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- groups
- alkyl
- halogenated
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110988568.9 | 2021-08-26 | ||
| CN202110988568 | 2021-08-26 | ||
| CN202210633028.3 | 2022-06-06 | ||
| CN202210633028 | 2022-06-06 | ||
| PCT/CN2022/115068 WO2023025277A1 (zh) | 2021-08-26 | 2022-08-26 | 含芳环类生物拮抗剂、其制备方法和应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024534111A JP2024534111A (ja) | 2024-09-18 |
| JP2024534111A5 true JP2024534111A5 (OSRAM) | 2025-07-18 |
Family
ID=85322470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024510689A Pending JP2024534111A (ja) | 2021-08-26 | 2022-08-26 | 芳香環系を含有する生物アンタゴニスト、その製造方法及び応用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20240368123A1 (OSRAM) |
| EP (1) | EP4393920A4 (OSRAM) |
| JP (1) | JP2024534111A (OSRAM) |
| KR (1) | KR20240051999A (OSRAM) |
| CN (1) | CN117836294A (OSRAM) |
| AU (1) | AU2022334402A1 (OSRAM) |
| CA (1) | CA3229397A1 (OSRAM) |
| MX (1) | MX2024002411A (OSRAM) |
| TW (1) | TW202328116A (OSRAM) |
| WO (1) | WO2023025277A1 (OSRAM) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7735563B2 (ja) * | 2021-10-21 | 2025-09-08 | ニコヤ セラピューティクス（シャンハイ）カンパニー リミテッド | 二重アンタゴニスト及びその使用 |
| WO2025094214A1 (en) * | 2023-11-02 | 2025-05-08 | Msn Laboratories Private Limited, R&D Center | Process for the preparation of 2-[4-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-2-(ethoxymethyl)phenyl]-N-(4,5-dimethyl-1,2-oxazol-3-yl) benzenesulfonamide and its intermediates thereof |
| IT202400000246A1 (it) * | 2024-01-09 | 2025-07-09 | Procos Spa | Processo per la preparazione di sparsentan |
| WO2026021516A1 (zh) * | 2024-07-25 | 2026-01-29 | 深圳信立泰药业股份有限公司 | 一种取代的血管紧张肽和内皮肽受体拮抗剂及其应用 |
| WO2026067819A1 (zh) * | 2024-09-30 | 2026-04-02 | 江苏豪森药业集团有限公司 | 含芳环类生物拮抗剂在制备治疗或预防肾脏疾病药物中的应用 |
| CN119462631A (zh) * | 2024-10-09 | 2025-02-18 | 广东莱佛士制药技术有限公司 | 一种司巴生坦中间体的合成方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06510763A (ja) * | 1991-08-19 | 1994-12-01 | イー・アイ・デュポン・ドゥ・ヌムール・アンド・カンパニー | アンジオテンシン２受容体遮断イミダゾリノン誘導体 |
| US6638937B2 (en) * | 1998-07-06 | 2003-10-28 | Bristol-Myers Squibb Co. | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
| PT1094816E (pt) * | 1998-07-06 | 2009-03-10 | Bristol Myers Squibb Co | Sulfonamidas bifenílicas duplamente antagonistas receptores de angiotensina e endotelina |
| EP1741713A3 (en) * | 1999-12-15 | 2009-09-09 | Bristol-Myers Squibb Company | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
| ES2259909B1 (es) * | 2005-02-28 | 2007-06-16 | Inke, S.A. | Procedimiento para la obtencion de un compuesto farmaceuticamente activo y de su intermedio de sintesis. |
| BRPI0708507A2 (pt) * | 2006-03-03 | 2011-05-31 | Torrent Pharmaceuticals Ltd | Novos antagonistas de receptores de dupla ação (dara) para os receptores at1 eta |
| WO2007109456A2 (en) * | 2006-03-16 | 2007-09-27 | Pharmacopeia, Inc. | Substituted biphenyl isoxazole sulfonamides as dual angiotensin endothelin receptor antagonists |
| ES2302671T1 (es) * | 2006-08-29 | 2008-08-01 | Teva Pharmaceutical Industries Ltd. | Procedimientos para la sintesis de 5-fenil-1-tritil-1h-tetrazol. |
| JP2011518884A (ja) * | 2008-04-29 | 2011-06-30 | セラヴァンス， インコーポレーテッド | 二重活性抗高血圧剤 |
| DK3222277T3 (da) | 2009-03-31 | 2020-05-11 | Ligand Pharm Inc | Biphenylsulfonamidendothelin- og angiotensin II-receptorantagonist til behandling af glomerulosklerose og IgA-induceret nefropati |
| WO2010135350A2 (en) * | 2009-05-20 | 2010-11-25 | Pharmacopeia, Llc | Biphenyl intermediate compounds and methods for the preparation of a dual angiotensin ii and endothelin a receptor antagonist |
| CN104761548B (zh) * | 2015-04-27 | 2017-09-12 | 梯尔希（南京）药物研发有限公司 | 一种稳定同位素标记的二苯基磺酰胺类药物的制备方法 |
| WO2018005591A1 (en) * | 2016-06-29 | 2018-01-04 | Universite De Montreal | Biarylmethyl heterocycles |
| MA46524A (fr) | 2016-10-13 | 2019-08-21 | Retrophin Inc | Composés de biphényl-sulfonamide destinés au traitement de néphropathies |
| CN112876424B (zh) * | 2019-11-29 | 2023-06-30 | 上海拓界生物医药科技有限公司 | 血管紧张素ii受体及内皮素受体双重拮抗剂 |
| JP7735563B2 (ja) * | 2021-10-21 | 2025-09-08 | ニコヤ セラピューティクス（シャンハイ）カンパニー リミテッド | 二重アンタゴニスト及びその使用 |
| JP2024178482A (ja) * | 2021-11-15 | 2024-12-25 | 株式会社アークメディスン | 化合物、アンジオテンシンｉｉタイプ１受容体拮抗剤及び医薬組成物 |
-
2022
- 2022-08-26 AU AU2022334402A patent/AU2022334402A1/en active Pending
- 2022-08-26 TW TW111132297A patent/TW202328116A/zh unknown
- 2022-08-26 CN CN202280056242.5A patent/CN117836294A/zh active Pending
- 2022-08-26 MX MX2024002411A patent/MX2024002411A/es unknown
- 2022-08-26 WO PCT/CN2022/115068 patent/WO2023025277A1/zh not_active Ceased
- 2022-08-26 JP JP2024510689A patent/JP2024534111A/ja active Pending
- 2022-08-26 US US18/685,883 patent/US20240368123A1/en active Pending
- 2022-08-26 CA CA3229397A patent/CA3229397A1/en active Pending
- 2022-08-26 EP EP22860623.2A patent/EP4393920A4/en active Pending
- 2022-08-26 KR KR1020247009542A patent/KR20240051999A/ko active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2715458T3 (es) | Inhibidores de dihidropirrolopiridina de ROR-gamma | |
| ES2977683T3 (es) | Derivados de bencimidazolona y análogos de los mismos, como moduladores de IL-17 | |
| ES2750655T3 (es) | Derivados de pirrolo[2,3-d]pirimidina útiles para inhibir la Janus cinasa | |
| US9175013B2 (en) | Fused aminodihydrothiazine derivatives | |
| US8592408B2 (en) | Fused aminodihydrothiazine derivatives | |
| US9840532B2 (en) | 5′-substituted nucleoside compounds | |
| ES2689526T3 (es) | Moduladores de P2X7 | |
| ES2714048T3 (es) | Moduladores de P2X7 | |
| RU2011147200A (ru) | Азетидинилдиамиды в качестве ингибиторов моноациглицерин-липазы | |
| TW202227389A (zh) | 新穎化合物 | |
| JP2019532052A5 (OSRAM) | ||
| CA2680157A1 (en) | Novel 2-heteroaryl substituted benzothiophenes and benzofuranes 709 | |
| JP6775009B2 (ja) | ３−ビシクロ［３．２．０］ヘプ−３−エン−６オンエンの鏡像異性体の分離 | |
| CN109790116A (zh) | Trpv4拮抗剂 | |
| PE20201151A1 (es) | Moduladores alostericos positivos del receptor de dopamina d1 | |
| JP5437525B1 (ja) | チロシン誘導体およびチロシン誘導体の製造方法 | |
| JP2004525972A5 (OSRAM) | ||
| ES2650139T3 (es) | Compuestos 3-fenilsulfanilmetil-biciclo[3.1.0]hexano 4-sustituidos como antagonistas de mGluR 2/3 | |
| CN117964637A (zh) | 一种新型肽基腈类化合物及其应用 | |
| WO2012171248A1 (zh) | 1,3-噁唑烷-2-酮类化合物、其制备方法和用途 | |
| JP2018140987A5 (OSRAM) | ||
| WO2014015125A1 (en) | Fused aminodihydrothiazine derivative salts and uses thereof | |
| JP6723250B2 (ja) | Ｎ−［３−［（４ａｒ，７ａｓ）−２−アミノ−６−（５−フルオロピリミジン−２−イル）−４，４ａ，５，７−テトラヒドロピロロ［３，４−ｄ］［１，３］チアジン−７ａ−イル］−４−フルオロ−フェニル］−５−メトキシ−ピラジン−２−カルボキサミドのトシル酸塩 | |
| WO2024088307A1 (zh) | 一种新型肽基腈类化合物及其应用 | |
| US9828390B2 (en) | Tetrahydropyrrolo[3,4-D][1,3]thiazine-derivative as BACE inhibitor |