JP2024527110A - 化学ルミネセンスシグナルを増大させる方法および試薬 - Google Patents

化学ルミネセンスシグナルを増大させる方法および試薬 Download PDF

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JP2024527110A
JP2024527110A JP2024505423A JP2024505423A JP2024527110A JP 2024527110 A JP2024527110 A JP 2024527110A JP 2024505423 A JP2024505423 A JP 2024505423A JP 2024505423 A JP2024505423 A JP 2024505423A JP 2024527110 A JP2024527110 A JP 2024527110A
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chloride
chemiluminescent
compound
alkyl
acridinium
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Japanese (ja)
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JP2024527110A5 (https=
Inventor
テウザー，マティアス
コモロフスキ，ラース
ダマーマン，アンティエ
バウメルト，カスリン
ホルシュテ，マレイケ
ヒンケルアンメルト，マルセル
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ユーロイミューン・メディツィニシェ・ラボルディアグノシュティカ・アクチエンゲゼルシャフト
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Publication of JP2024527110A publication Critical patent/JP2024527110A/ja
Publication of JP2024527110A5 publication Critical patent/JP2024527110A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B15/00—Acridine dyes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/0033—Blends of pigments; Mixtured crystals; Solid solutions
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/0033—Blends of pigments; Mixtured crystals; Solid solutions
    • C09B67/0034—Mixtures of two or more pigments or dyes of the same type
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/06—Luminescent materials, e.g. electroluminescent or chemiluminescent containing organic luminescent materials
    • C09K11/07—Luminescent materials, e.g. electroluminescent or chemiluminescent containing organic luminescent materials having chemically-interreactive components, e.g. reactive chemiluminescent compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/10—Non-macromolecular compounds
    • C09K2211/1003—Carbocyclic compounds
    • C09K2211/1007—Non-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/10—Non-macromolecular compounds
    • C09K2211/1018—Heterocyclic compounds

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2024505423A 2021-07-29 2022-07-21 化学ルミネセンスシグナルを増大させる方法および試薬 Pending JP2024527110A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21188638 2021-07-29
EP21188638.7 2021-07-29
PCT/EP2022/070522 WO2023006581A1 (en) 2021-07-29 2022-07-21 A method and reagents for enhancing the chemiluminescent signal

Publications (2)

Publication Number Publication Date
JP2024527110A true JP2024527110A (ja) 2024-07-19
JP2024527110A5 JP2024527110A5 (https=) 2025-07-29

Family

ID=77155594

Family Applications (1)

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JP2024505423A Pending JP2024527110A (ja) 2021-07-29 2022-07-21 化学ルミネセンスシグナルを増大させる方法および試薬

Country Status (9)

Country Link
US (1) US20240353412A1 (https=)
EP (1) EP4146765B1 (https=)
JP (1) JP2024527110A (https=)
CN (1) CN117769588B (https=)
CA (1) CA3221813A1 (https=)
DE (1) DE112022003796T5 (https=)
ES (1) ES2952362T3 (https=)
PL (1) PL4146765T3 (https=)
WO (1) WO2023006581A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115980332B (zh) * 2023-03-20 2023-07-04 广州科方生物技术股份有限公司 一种可提高免疫诊断试剂灵敏度的增强液及其制配方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US915527A (en) 1908-04-14 1909-03-16 James C Wood Potato-planter.
US4927769A (en) 1987-07-08 1990-05-22 Ciba Corning Diagnostics Corp. Method for enhancement of chemiluminescence
GB2233451B (en) * 1989-06-27 1993-09-15 Tropix Inc Chemiluminescence enhancement
US5451347A (en) * 1993-06-24 1995-09-19 Lumigen, Inc. Methods and compositions providing enhanced chemiluminescence from chemiluminescent compounds using dicationic surfactants
US5879885A (en) * 1995-06-07 1999-03-09 Gen-Probe Incorporated Compositions for detecting and quantifying biological samples
US6664043B2 (en) 2001-07-03 2003-12-16 Bayer Corporation Acridinium ester labels having hydrophilic modifiers
ATE553089T1 (de) 2002-08-20 2012-04-15 Quest Diagnostics Invest Inc Hydrophile, chemilumineszente acridiniummarkierungsreagenzien
CN102311730B (zh) * 2010-06-30 2014-09-24 深圳迈瑞生物医疗电子股份有限公司 化学发光液,增强化学发光的试剂和方法
CN102311731B (zh) * 2010-06-30 2016-08-03 深圳迈瑞生物医疗电子股份有限公司 增强化学发光的试剂、方法和化学发光液
US20130168620A1 (en) * 2011-12-30 2013-07-04 Maggilume, LLC Chemiluminescent system
ES2769887T3 (es) * 2013-05-14 2020-06-29 Siemens Healthcare Diagnostics Inc Tensioactivos catiónicos degradables y su uso para la mejora de la quimioluminiscencia
CN109425741A (zh) * 2017-08-31 2019-03-05 苏州长光华医生物医学工程有限公司 一种适用于吖啶酯发光体系的化学发光底物液

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Publication number Publication date
EP4146765A1 (en) 2023-03-15
WO2023006581A1 (en) 2023-02-02
EP4146765C0 (en) 2023-07-05
US20240353412A1 (en) 2024-10-24
ES2952362T3 (es) 2023-10-31
DE112022003796T5 (de) 2024-06-20
CA3221813A1 (en) 2023-02-02
CN117769588A (zh) 2024-03-26
PL4146765T3 (pl) 2023-12-11
CN117769588B (zh) 2025-02-21
EP4146765B1 (en) 2023-07-05

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