JP2024525044A5 - - Google Patents

Info

Publication number
JP2024525044A5
JP2024525044A5 JP2023580802A JP2023580802A JP2024525044A5 JP 2024525044 A5 JP2024525044 A5 JP 2024525044A5 JP 2023580802 A JP2023580802 A JP 2023580802A JP 2023580802 A JP2023580802 A JP 2023580802A JP 2024525044 A5 JP2024525044 A5 JP 2024525044A5
Authority
JP
Japan
Prior art keywords
methyl
imidazo
triazine
carbonyl
carboxamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023580802A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024525044A (ja
Filing date
Publication date
Priority claimed from GBGB2109520.3A external-priority patent/GB202109520D0/en
Priority claimed from GBGB2203876.4A external-priority patent/GB202203876D0/en
Application filed filed Critical
Priority claimed from PCT/EP2022/068165 external-priority patent/WO2023275301A1/en
Publication of JP2024525044A publication Critical patent/JP2024525044A/ja
Publication of JP2024525044A5 publication Critical patent/JP2024525044A5/ja
Pending legal-status Critical Current

Links

JP2023580802A 2021-07-01 2022-06-30 Il-17モジュレータとしてのイミダゾトリアジン誘導体 Pending JP2024525044A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB2109520.3 2021-07-01
GBGB2109520.3A GB202109520D0 (en) 2021-07-01 2021-07-01 Therapeutic agents
GBGB2203876.4A GB202203876D0 (en) 2022-03-21 2022-03-21 Therapeutic agents
GB2203876.4 2022-03-21
PCT/EP2022/068165 WO2023275301A1 (en) 2021-07-01 2022-06-30 Imidazotriazine derivatives as il-17 modulators

Publications (2)

Publication Number Publication Date
JP2024525044A JP2024525044A (ja) 2024-07-09
JP2024525044A5 true JP2024525044A5 (enExample) 2025-06-25

Family

ID=82493962

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023580802A Pending JP2024525044A (ja) 2021-07-01 2022-06-30 Il-17モジュレータとしてのイミダゾトリアジン誘導体

Country Status (6)

Country Link
US (1) US20240294534A1 (enExample)
EP (1) EP4363421A1 (enExample)
JP (1) JP2024525044A (enExample)
AR (1) AR126255A1 (enExample)
TW (1) TW202317576A (enExample)
WO (1) WO2023275301A1 (enExample)

Families Citing this family (20)

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Publication number Priority date Publication date Assignee Title
GB201909190D0 (en) * 2019-06-26 2019-08-07 Ucb Biopharma Sprl Therapeutic agents
GB202210731D0 (en) 2022-07-22 2022-09-07 UCB Biopharma SRL Therapeutic agents
WO2024115662A1 (en) 2022-12-02 2024-06-06 Leo Pharma A/S Small molecule modulators of il-17
GB202218846D0 (en) 2022-12-14 2023-01-25 UCB Biopharma SRL Therapeutic agents
GB202218860D0 (en) 2022-12-14 2023-01-25 Ucb Biopharma Sprl Therapeutic agents
WO2024126249A1 (en) 2022-12-14 2024-06-20 UCB Biopharma SRL Imidazotriazine derivatives as il-17 modulators
IL322551A (en) * 2023-02-13 2025-10-01 Dice Alpha Inc Imidazotriazine IL-17a modulators and their uses
CN121311483A (zh) * 2023-03-28 2026-01-09 詹森药业有限公司 含内酰胺的咪唑并哒嗪il-17抑制剂化合物
GB202305587D0 (en) 2023-04-17 2023-05-31 UCB Biopharma SRL Therapeutic agents
GB202305585D0 (en) 2023-04-17 2023-05-31 UCB Biopharma SRL Therapeutic agents
CN117551093B (zh) * 2023-11-14 2024-06-18 山东天锐医药科技有限公司 马来酸阿伐曲泊帕起始原料4-(4-氯-2-噻吩基)-2-噻唑胺的制备方法
WO2026012492A1 (en) * 2024-07-12 2026-01-15 Anew Therapeutics Pte. Ltd. Heterocyclic compounds as il-17 inhibitors
WO2026039171A1 (en) * 2024-08-12 2026-02-19 Dice Alpha, Inc. Il-17a inhibitors
WO2026039170A1 (en) * 2024-08-12 2026-02-19 Dice Alpha, Inc. Il-17a inhibitors
WO2026039168A1 (en) * 2024-08-12 2026-02-19 Dice Alpha, Inc. Il-17a inhibitors
WO2026039172A1 (en) * 2024-08-12 2026-02-19 Dice Alpha, Inc. Il-17a inhibitors
WO2026039167A1 (en) * 2024-08-12 2026-02-19 Dice Alpha, Inc. Il-17a inhibitors
WO2026073936A1 (en) 2024-10-02 2026-04-09 UCB Biopharma SRL Imidazotriazine derivatives as il-17 modulators
WO2026073929A1 (en) 2024-10-02 2026-04-09 UCB Biopharma SRL Imidazotriazine derivatives as il-17 modulators
WO2026073937A1 (en) 2024-10-02 2026-04-09 UCB Biopharma SRL Imidazotriazine derivatives as il-17 modulators

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AU2009204441B2 (en) 2008-01-09 2015-03-05 The Schepens Eye Research Institute, Inc. Therapeutic compositions for treatment of ocular inflammatory disorders
WO2013116682A1 (en) 2012-02-02 2013-08-08 Ensemble Therapeutics Corporation Macrocyclic compounds for modulating il-17
WO2014066726A2 (en) 2012-10-26 2014-05-01 Ensemble Therapeutics Corporation Compounds for modulating il-17
WO2018098189A1 (en) 2016-11-22 2018-05-31 Hepatochem, Inc. Photochemistry device
GB201709456D0 (en) 2017-06-14 2017-07-26 Ucb Biopharma Sprl Therapeutic agents
EP3740478B1 (en) 2018-01-15 2023-11-01 UCB Biopharma SRL Fused imidazole derivatives as il-17 modulators
WO2019223718A1 (zh) 2018-05-22 2019-11-28 成都先导药物开发股份有限公司 一种免疫调节剂
CA3103711A1 (en) 2018-07-12 2020-01-16 UCB Biopharma SRL Spirocyclic indane analogues as il-17 modulators
GB201820166D0 (en) 2018-12-11 2019-01-23 Ucb Biopharma Sprl Therapeutic agents
GB201820165D0 (en) 2018-12-11 2019-01-23 Ucb Biopharma Sprl Therapeutic agents
CN113164448A (zh) 2018-12-19 2021-07-23 利奥制药有限公司 作为il-17的小分子调节剂的氨基酸苯胺类化合物
TW202214648A (zh) 2019-01-07 2022-04-16 美商美國禮來大藥廠 Il-17a抑制劑
US20220162191A1 (en) 2019-03-08 2022-05-26 Leo Pharma A/S Small molecule modulators of il-17
GB201909190D0 (en) * 2019-06-26 2019-08-07 Ucb Biopharma Sprl Therapeutic agents
GB201909194D0 (en) 2019-06-26 2019-08-07 Ucb Biopharma Sprl Therapeutic agents
GB201909191D0 (en) 2019-06-26 2019-08-07 Ucb Biopharma Sprl Therapeutic agents
CN112341446B (zh) 2019-08-09 2022-06-17 成都先导药物开发股份有限公司 一种免疫调节剂
WO2021027721A1 (zh) 2019-08-09 2021-02-18 成都先导药物开发股份有限公司 一种免疫调节剂
WO2021027724A1 (zh) 2019-08-09 2021-02-18 成都先导药物开发股份有限公司 一种免疫调节剂
WO2021027729A1 (zh) 2019-08-09 2021-02-18 成都先导药物开发股份有限公司 一种免疫调节剂
WO2021098844A1 (zh) 2019-11-20 2021-05-27 成都先导药物开发股份有限公司 一种免疫调节剂
WO2021170627A1 (en) 2020-02-25 2021-09-02 UCB Biopharma SRL Difluorocyclohexyl derivatives as il-17 modulators
WO2021170631A1 (en) 2020-02-25 2021-09-02 UCB Biopharma SRL Difluorocyclohexyl derivatives as il-17 modulators
WO2021204800A1 (en) 2020-04-07 2021-10-14 UCB Biopharma SRL Difluorocyclohexyl derivatives as il-17 modulators
JP7682920B2 (ja) 2020-04-07 2025-05-26 ユーシービー バイオファルマ エスアールエル Il-17モジュレータとしてのジフルオロシクロヘキシル誘導体
CN116406267A (zh) 2020-11-09 2023-07-07 Ucb生物制药有限责任公司 作为il-17调节剂的二环丙基甲基衍生物
WO2022096411A1 (en) 2020-11-09 2022-05-12 UCB Biopharma SRL Dicyclopropylmethyl derivatives as il-17 modulators
EP4259631A1 (en) 2020-12-14 2023-10-18 UCB Biopharma SRL Imidazopyridazine derivatives as il-17 modulators

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