JP2018522847A5 - - Google Patents
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- Publication number
- JP2018522847A5 JP2018522847A5 JP2017564846A JP2017564846A JP2018522847A5 JP 2018522847 A5 JP2018522847 A5 JP 2018522847A5 JP 2017564846 A JP2017564846 A JP 2017564846A JP 2017564846 A JP2017564846 A JP 2017564846A JP 2018522847 A5 JP2018522847 A5 JP 2018522847A5
- Authority
- JP
- Japan
- Prior art keywords
- tetrahydro
- pyridin
- oxo
- phenylamino
- indole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2015/063527 WO2015193339A1 (en) | 2014-06-17 | 2015-06-17 | 3-amino-1,5,6,7-tetrahydro-4h-indol-4-ones |
| EP15172613 | 2015-06-17 | ||
| EP15172613.0 | 2015-06-17 | ||
| EPPCT/EP2015/063527 | 2015-06-17 | ||
| EP15177393 | 2015-07-17 | ||
| EP15177393.4 | 2015-07-17 | ||
| PCT/EP2016/063540 WO2016202755A1 (en) | 2015-06-17 | 2016-06-14 | 3-amino-1,5,6,7-tetrahydro-4h-indol-4-ones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018522847A JP2018522847A (ja) | 2018-08-16 |
| JP2018522847A5 true JP2018522847A5 (enExample) | 2019-04-04 |
Family
ID=57545595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017564846A Withdrawn JP2018522847A (ja) | 2015-06-17 | 2016-06-14 | ３−アミノ−１，５，６，７−テトラヒドロ−４ｈ−インドール−４−オン類 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10227299B2 (enExample) |
| EP (1) | EP3310775B1 (enExample) |
| JP (1) | JP2018522847A (enExample) |
| CN (1) | CN107922389A (enExample) |
| CA (1) | CA2989469A1 (enExample) |
| TW (1) | TW201718534A (enExample) |
| UY (1) | UY36737A (enExample) |
| WO (1) | WO2016202755A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015193339A1 (en) * | 2014-06-17 | 2015-12-23 | Bayer Pharma Aktiengesellschaft | 3-amino-1,5,6,7-tetrahydro-4h-indol-4-ones |
| CN107406417B (zh) | 2015-01-28 | 2020-06-09 | 拜耳制药股份公司 | 4H-吡咯并[3,2-c]吡啶-4-酮衍生物 |
| WO2018158175A1 (en) | 2017-02-28 | 2018-09-07 | Bayer Pharma Aktiengesellschaft | Combination of bub1 inhibitors |
| EP4217070A1 (en) | 2020-09-23 | 2023-08-02 | Scorpion Therapeutics, Inc. | Pyrrolo[3,2-c]pyridin-4-one derivatives useful in the treatment of cancer |
| TW202229282A (zh) | 2020-09-30 | 2022-08-01 | 美商史考皮恩治療有限公司 | 治療癌症之方法 |
| WO2022072645A2 (en) | 2020-09-30 | 2022-04-07 | Scorpion Therapeutics, Inc. | Methods for treating cancer |
| AU2021358123A1 (en) | 2020-10-05 | 2023-06-08 | Enliven Inc. | 5- and 6-azaindole compounds for inhibition of bcr-abl tyrosine kinases |
| JP2023548657A (ja) | 2020-10-09 | 2023-11-20 | スコーピオン セラピューティクス インコーポレイテッド | がんの処置に使用するための、ｅｇｆｒおよび／またはｈｅｒ２のヘテロ環阻害剤 |
| WO2022094271A1 (en) | 2020-10-30 | 2022-05-05 | Scorpion Therapeutics, Inc. | Methods for treating cancer |
| WO2022098992A1 (en) | 2020-11-05 | 2022-05-12 | Scorpion Therapeutics, Inc. | Use of macrocyclic compounds in methods of treating cancer |
| WO2022197913A1 (en) | 2021-03-18 | 2022-09-22 | Scorpion Therapeutics, Inc. | Bicyclic derivatives which can be used to treat cancer |
| WO2023173083A1 (en) | 2022-03-11 | 2023-09-14 | Scorpion Therapeutics, Inc. | Tetrahydroindole derivatives as egfr and/or her2 inhibtors useful for the treatment of cancer |
| WO2024159094A1 (en) * | 2023-01-27 | 2024-08-02 | Enliven Inc. | Pyrimidinyl (hetero)aromatic aminopyridine compounds for inhibition of raf kinases |
| WO2024254266A1 (en) | 2023-06-08 | 2024-12-12 | Scorpion Therapeutics, Inc. | A 1,5-dihydro-4h-pyrrolo[3,2-c] pyridin-4-one for use in the treatment of cancer |
| WO2024254298A1 (en) | 2023-06-08 | 2024-12-12 | Scorpion Therapeutics, Inc. | A 1,5-dihydro-4h-pyrrolo[3,2-c] pyridin-4-one for use in the treatment of cancer |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA111754C2 (uk) * | 2011-10-06 | 2016-06-10 | Байєр Фарма Акцієнгезелльшафт | Заміщені бензиліндазоли для застосування як інгібіторів bub1-кінази для лікування гіперпроліферативних захворювань |
| JP6141866B2 (ja) | 2011-12-21 | 2017-06-07 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ | 置換ベンジルピラゾール類 |
| HK1207861A1 (en) * | 2012-05-11 | 2016-02-12 | Bayer Pharma Aktiengesellschaft | Substituted cycloalkenopyrazoles as bub1 inhibitors for the treatment of cancer |
| EP2976336A1 (en) | 2013-03-21 | 2016-01-27 | Bayer Pharma Aktiengesellschaft | 3-heteroaryl substituted indazoles |
| WO2014147204A1 (en) | 2013-03-21 | 2014-09-25 | Bayer Pharma Aktiengesellschaft | Heteroaryl substituted indazoles |
| EP3010911A1 (en) | 2013-06-21 | 2016-04-27 | Bayer Pharma Aktiengesellschaft | Heteroaryl substituted pyrazoles |
| JP2016525076A (ja) | 2013-06-21 | 2016-08-22 | バイエル ファーマ アクチエンゲゼルシャフト | 置換されたベンジルピラゾール類 |
| EP3010901B1 (en) | 2013-06-21 | 2017-09-13 | Bayer Pharma Aktiengesellschaft | Heteroaryl substituted pyrazoles |
| EP3010902A1 (en) | 2013-06-21 | 2016-04-27 | Bayer Pharma Aktiengesellschaft | Substituted benzylpyrazoles |
| WO2015063003A1 (en) | 2013-10-30 | 2015-05-07 | Bayer Pharma Aktiengesellschaft | Heteroaryl substituted pyrazoles |
| WO2015193339A1 (en) | 2014-06-17 | 2015-12-23 | Bayer Pharma Aktiengesellschaft | 3-amino-1,5,6,7-tetrahydro-4h-indol-4-ones |
| CN107406417B (zh) | 2015-01-28 | 2020-06-09 | 拜耳制药股份公司 | 4H-吡咯并[3,2-c]吡啶-4-酮衍生物 |
| EP3331611B1 (en) * | 2015-08-05 | 2021-06-02 | Bayer Pharma Aktiengesellschaft | 1h-pyrrol-3-amines |
| CA3008393A1 (en) | 2015-12-16 | 2017-06-22 | Bayer Pharma Aktiengesellschaft | Hetero-1,5,6,7-tetrahydro-4h-indol-4-ones |
-
2016
- 2016-06-14 CA CA2989469A patent/CA2989469A1/en not_active Abandoned
- 2016-06-14 JP JP2017564846A patent/JP2018522847A/ja not_active Withdrawn
- 2016-06-14 EP EP16734202.1A patent/EP3310775B1/en active Active
- 2016-06-14 WO PCT/EP2016/063540 patent/WO2016202755A1/en not_active Ceased
- 2016-06-14 US US15/737,182 patent/US10227299B2/en not_active Expired - Fee Related
- 2016-06-14 CN CN201680046760.3A patent/CN107922389A/zh active Pending
- 2016-06-16 UY UY0001036737A patent/UY36737A/es not_active Application Discontinuation
- 2016-06-17 TW TW105119236A patent/TW201718534A/zh unknown
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