JP2024523394A5 - - Google Patents

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Publication number
JP2024523394A5
JP2024523394A5 JP2023577861A JP2023577861A JP2024523394A5 JP 2024523394 A5 JP2024523394 A5 JP 2024523394A5 JP 2023577861 A JP2023577861 A JP 2023577861A JP 2023577861 A JP2023577861 A JP 2023577861A JP 2024523394 A5 JP2024523394 A5 JP 2024523394A5
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JP
Japan
Prior art keywords
item
target gene
krab
complex
dnmt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023577861A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024523394A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/033797 external-priority patent/WO2022266324A1/en
Publication of JP2024523394A publication Critical patent/JP2024523394A/ja
Publication of JP2024523394A5 publication Critical patent/JP2024523394A5/ja
Pending legal-status Critical Current

Links

JP2023577861A 2021-06-17 2022-06-16 異常な遺伝子発現を調節するためのシステムおよび方法 Pending JP2024523394A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163211791P 2021-06-17 2021-06-17
US63/211,791 2021-06-17
PCT/US2022/033797 WO2022266324A1 (en) 2021-06-17 2022-06-16 Systems and methods for regulating aberrant gene expressions

Publications (2)

Publication Number Publication Date
JP2024523394A JP2024523394A (ja) 2024-06-28
JP2024523394A5 true JP2024523394A5 (enExample) 2025-06-13

Family

ID=84525869

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023577861A Pending JP2024523394A (ja) 2021-06-17 2022-06-16 異常な遺伝子発現を調節するためのシステムおよび方法

Country Status (11)

Country Link
US (1) US20240216482A1 (enExample)
EP (1) EP4355357A4 (enExample)
JP (1) JP2024523394A (enExample)
KR (1) KR20240032038A (enExample)
CN (1) CN117940150A (enExample)
AU (1) AU2022293494A1 (enExample)
CA (1) CA3221874A1 (enExample)
GB (1) GB2624791A (enExample)
IL (1) IL309174A (enExample)
MX (1) MX2023014750A (enExample)
WO (1) WO2022266324A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230076820A (ko) 2020-09-01 2023-05-31 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 진핵생물 유전체 공학을 위한 합성 미니어처 crispr-cas(casmini) 시스템
JP2025507822A (ja) 2022-03-01 2025-03-21 エピクリスパー バイオテクノロジーズ, インコーポレイテッド 組換えヌクレアーゼならびにその組成物および使用方法
CN121127598A (zh) * 2023-03-16 2025-12-12 埃皮克里斯皮尔生物技术公司 用于调控异常基因表达的系统和方法
CN119955797B (zh) * 2025-01-13 2026-01-23 江南大学 Kif5b基因在调控成肌细胞生理活性中的功能和应用
CN119954926B (zh) * 2025-03-11 2025-10-28 华南农业大学 Klf5转录因子在调控猪骨骼肌发育中的应用及方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1107789B1 (en) 1998-08-24 2008-06-25 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for protecting organs, tissue and cells from immune system-mediated damage
EP3443081A4 (en) * 2016-04-13 2019-10-30 Duke University CRISPR / CAS9-BASED REPRESSORS FOR IN VIVO SHUT-OFF OF GEN-TARGETS AND METHOD OF USE
EP3515506B1 (en) * 2016-09-23 2023-09-13 University of Massachusetts Silencing of dux4 by recombinant gene editing complexes
US11160823B2 (en) * 2016-11-07 2021-11-02 University Of Massachusetts Therapeutic targets for facioscapulohumeral muscular dystrophy
US11807877B1 (en) * 2018-03-22 2023-11-07 National Technology & Engineering Solutions Of Sandia, Llc CRISPR/Cas activity assays and compositions thereof
JP2022516515A (ja) * 2018-12-31 2022-02-28 リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル Rna標的化crispr-cas13bを使用するdux4 rna発現停止
WO2020142739A1 (en) * 2019-01-04 2020-07-09 Mammoth Biosciences, Inc. COMPOSITIONS AND METHODS FOR DETECTING MODIFIED NUCLEIC ACIDS AND AMPLIFYING ssDNA
WO2022133062A1 (en) * 2020-12-16 2022-06-23 Epicrispr Biotechnologies, Inc. Systems and methods for engineering characteristics of a cell

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