JP2024521757A5 - - Google Patents

Info

Publication number
JP2024521757A5
JP2024521757A5 JP2023572618A JP2023572618A JP2024521757A5 JP 2024521757 A5 JP2024521757 A5 JP 2024521757A5 JP 2023572618 A JP2023572618 A JP 2023572618A JP 2023572618 A JP2023572618 A JP 2023572618A JP 2024521757 A5 JP2024521757 A5 JP 2024521757A5
Authority
JP
Japan
Prior art keywords
oeg
cooh
insulin analog
human insulin
desb30 human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023572618A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024521757A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2022/094392 external-priority patent/WO2022247773A1/en
Publication of JP2024521757A publication Critical patent/JP2024521757A/ja
Publication of JP2024521757A5 publication Critical patent/JP2024521757A5/ja
Pending legal-status Critical Current

Links

JP2023572618A 2021-05-24 2022-05-23 新規なアシル化インスリンアナログ Pending JP2024521757A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202110570030 2021-05-24
CN202110570030.6 2021-05-24
PCT/CN2022/094392 WO2022247773A1 (en) 2021-05-24 2022-05-23 A novel acylated insulin analog

Publications (2)

Publication Number Publication Date
JP2024521757A JP2024521757A (ja) 2024-06-04
JP2024521757A5 true JP2024521757A5 (enExample) 2025-06-03

Family

ID=84115321

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023572618A Pending JP2024521757A (ja) 2021-05-24 2022-05-23 新規なアシル化インスリンアナログ

Country Status (8)

Country Link
US (1) US20240374692A1 (enExample)
EP (1) EP4347632A4 (enExample)
JP (1) JP2024521757A (enExample)
KR (1) KR20240013778A (enExample)
CN (1) CN115385843A (enExample)
AU (1) AU2022283328A1 (enExample)
CA (1) CA3217734A1 (enExample)
WO (1) WO2022247773A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2026517987A (ja) * 2023-05-24 2026-06-02 ザ ユナイテッド バイオテクノロジー(ヘンチン)シーオー.,エルティーディー. インスリン誘導体およびその使用
WO2025098457A1 (zh) * 2023-11-07 2025-05-15 甘李药业股份有限公司 用于降糖的酰化胰岛素
CN122555570A (zh) * 2023-11-08 2026-08-11 甘李药业股份有限公司 包含胰岛素衍生物的药物组合物的治疗用途
CN117756914B (zh) * 2023-12-15 2024-09-03 瀚晖制药有限公司 依柯胰岛素的制备方法
CN118063589A (zh) * 2024-02-04 2024-05-24 乐普健糖药业(重庆)有限公司 一种超长效胰岛素类似物及其制备方法和用途
WO2025228255A1 (zh) * 2024-04-28 2025-11-06 正大天晴药业集团股份有限公司 酰化人胰岛素类似物
WO2026109062A1 (zh) * 2024-11-25 2026-05-28 甘李药业股份有限公司 含酰化胰岛素的药物组合物

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1888104A2 (en) * 2005-05-26 2008-02-20 Novo Nordisk A/S Acylated insulin with high purity
WO2007104737A1 (en) * 2006-03-13 2007-09-20 Novo Nordisk A/S Acylated single chain insulin
CN101437849B (zh) * 2006-05-09 2015-09-30 诺沃-诺迪斯克有限公司 胰岛素衍生物
AU2008288413B2 (en) * 2007-08-15 2013-09-26 Novo Nordisk A/S Insulin analogues with an acyl and aklylene glycol moiety
HUE032284T2 (en) * 2008-03-18 2017-09-28 Novo Nordisk As Protease-stabilized, acylated insulin analogues
CN102149411A (zh) * 2008-09-12 2011-08-10 诺沃—诺迪斯克有限公司 酰化肽或蛋白的方法
CN104788556A (zh) * 2011-12-15 2015-07-22 上海恒瑞医药有限公司 人胰岛素类似物及其酰化衍生物
WO2014009316A1 (en) * 2012-07-09 2014-01-16 Novo Nordisk A/S Novel use of insulin derivatives
CA2926701A1 (en) 2013-10-07 2015-04-16 Novo Nordisk A/S Novel derivative of an insulin analogue
AR099569A1 (es) * 2014-02-28 2016-08-03 Novo Nordisk As Derivados de insulina y los usos médicos de estos
US9856292B2 (en) * 2014-11-14 2018-01-02 Bristol-Myers Squibb Company Immunomodulators
EP3341401A1 (en) * 2015-08-25 2018-07-04 Novo Nordisk A/S Novel insulin derivatives and the medical uses hereof
BR112018002416A2 (pt) * 2015-08-25 2018-09-18 Novo Nordisk As derivados de insulina e seus usos médicos
US10815287B2 (en) 2016-08-02 2020-10-27 Jiangsu Hengrui Medicine Co., Ltd. Acylated derivative of human insulin or analogue thereof
WO2019149245A1 (zh) * 2018-02-01 2019-08-08 江苏恒瑞医药股份有限公司 含人胰岛素类似物的酰化衍生物的药物组合物及其制备方法
BR112022013009A2 (pt) * 2019-12-30 2022-09-06 Gan & Lee Pharmaceuticals Co Ltd Derivados de insulina, composição farmacêutica, uso do derivado da insulina e métodos para tratar ou prevenir diabetes, para aumentar a capacidade de um derivado de insulina e para aumentar a potência de um derivado de insulina
JP2020117542A (ja) * 2020-05-07 2020-08-06 ノヴォ ノルディスク アー/エス 錠剤コアとポリビニルアルコールコーティングとを含む経口インスリン投与のための医薬組成物

Similar Documents

Publication Publication Date Title
JP5249016B2 (ja) タキサン類の高分子結合体
JP2019526537A5 (enExample)
CN1187361C (zh) 磷酸取代的苯并氮杂卓酮-n-醋酸衍生物、制法和药物
JP2022509568A5 (enExample)
EP2344529B1 (fr) Nouveaux composes octapeptidiques derives de la somatostatine et leur utilisation therapeutique
JP2012512901A5 (enExample)
CA3084688A1 (fr) Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes
WO2019110773A1 (fr) Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes
JP2015531789A5 (enExample)
JP2010504934A5 (enExample)
WO2019110774A1 (fr) Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes
JP2016523241A5 (enExample)
LU87633A1 (fr) Derives peptidiques
CA3166495A1 (en) Insulin derivative
RU2014127270A (ru) Аналог человеческого инсулина и его ацилированное производное
EP2361241A1 (fr) Procede de synthese d'un omega-aminoacide ou ester a partir d'un acide ou ester gras mono-insature
LU86697A1 (fr) Nouveaux derives de la calcitonine,leur preparation et leur utilisation comme medicaments
JP2019526537A (ja) ヒトインスリンまたはそのアナログのアシル化誘導体
RU2020108281A (ru) Новые ацилированные аналоги инсулина и варианты их применения
JP2023516886A5 (enExample)
EP3740227A1 (fr) Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
WO2013072466A1 (fr) Procede de fabrication de composes comprenant des fonctions nitriles
WO2019243628A1 (fr) Composition injectable a ph 7 comprenant un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes et au moins une insuline basale presentant au moins un effet prandial et un effet basal
JP2013527178A5 (enExample)
EP0511903A2 (fr) Conjugué de calcitonine et de polyéthylène glycol