JP2019526537A5 - - Google Patents
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- Publication number
- JP2019526537A5 JP2019526537A5 JP2019503703A JP2019503703A JP2019526537A5 JP 2019526537 A5 JP2019526537 A5 JP 2019526537A5 JP 2019503703 A JP2019503703 A JP 2019503703A JP 2019503703 A JP2019503703 A JP 2019503703A JP 2019526537 A5 JP2019526537 A5 JP 2019526537A5
- Authority
- JP
- Japan
- Prior art keywords
- human insulin
- zinc complex
- acylated derivative
- group
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022066071A JP2022095872A (ja) | 2016-08-02 | 2022-04-13 | ヒトインスリンまたはそのアナログのアシル化誘導体 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610625257 | 2016-08-02 | ||
| CN201610625257.5 | 2016-08-02 | ||
| CN201610779132 | 2016-08-31 | ||
| CN201610779132.8 | 2016-08-31 | ||
| PCT/CN2017/095377 WO2018024186A1 (zh) | 2016-08-02 | 2017-08-01 | 一种人胰岛素或其类似物的酰化衍生物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022066071A Division JP2022095872A (ja) | 2016-08-02 | 2022-04-13 | ヒトインスリンまたはそのアナログのアシル化誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019526537A JP2019526537A (ja) | 2019-09-19 |
| JP2019526537A5 true JP2019526537A5 (enExample) | 2020-07-02 |
| JP7432361B2 JP7432361B2 (ja) | 2024-02-16 |
Family
ID=61074099
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019503703A Active JP7432361B2 (ja) | 2016-08-02 | 2017-08-01 | ヒトインスリンまたはそのアナログのアシル化誘導体 |
| JP2022066071A Pending JP2022095872A (ja) | 2016-08-02 | 2022-04-13 | ヒトインスリンまたはそのアナログのアシル化誘導体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022066071A Pending JP2022095872A (ja) | 2016-08-02 | 2022-04-13 | ヒトインスリンまたはそのアナログのアシル化誘導体 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10815287B2 (enExample) |
| EP (1) | EP3495384A4 (enExample) |
| JP (2) | JP7432361B2 (enExample) |
| CN (2) | CN108463468B (enExample) |
| TW (1) | TWI747929B (enExample) |
| WO (1) | WO2018024186A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021512124A (ja) * | 2018-02-01 | 2021-05-13 | 江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司Ｊｉａｎｇｓｕ Ｈｅｎｇｒｕｉ Ｍｅｄｉｃｉｎｅ Ｃｏ．， Ｌｔｄ． | ヒトインスリンアナログのアシル化誘導体を含有する医薬組成物及びその調製方法 |
| CN111094572B (zh) | 2018-02-09 | 2023-04-04 | 江苏恒瑞医药股份有限公司 | 一种密码子优化的人胰岛素类似物前体基因和信号肽基因 |
| EP3805257A4 (en) | 2018-05-24 | 2022-03-16 | Jiangsu Hengrui Medicine Co., Ltd. | METHOD OF PRODUCTION OF A PRECURSOR OF RECOMBINANT HUMAN INSULIN OR ANALOGUE THEREOF |
| KR20210102347A (ko) | 2018-12-11 | 2021-08-19 | 사노피 | 인슐린 수용체 결합 친화성이 감소된 인슐린 유사체 |
| CN118754967A (zh) | 2019-12-30 | 2024-10-11 | 甘李药业股份有限公司 | 胰岛素衍生物 |
| TW202229324A (zh) * | 2020-11-27 | 2022-08-01 | 大陸商江蘇恒瑞醫藥股份有限公司 | 製備胰島素或其類似物的醯化衍生物的方法 |
| CN112939771A (zh) * | 2021-01-28 | 2021-06-11 | 宁夏蓝博思化学技术有限公司 | 长链烷基二酸单叔丁酯的制备方法 |
| CN115385843A (zh) * | 2021-05-24 | 2022-11-25 | 广东东阳光药业有限公司 | 一种新型的酰化胰岛素类似物 |
| AU2022300061A1 (en) | 2021-06-25 | 2024-02-01 | Gan & Lee Pharmaceuticals Co., Ltd. | Acylated insulin-containing pharmaceutical composition |
| US20250340610A1 (en) | 2022-01-28 | 2025-11-06 | Gan & Lee Pharmaceuticals Co., Ltd. | Acylated insulin |
| CN117756914B (zh) * | 2023-12-15 | 2024-09-03 | 瀚晖制药有限公司 | 依柯胰岛素的制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH25772A (en) | 1985-08-30 | 1991-10-18 | Novo Industri As | Insulin analogues, process for their preparation |
| EP1132404A3 (en) | 1993-09-17 | 2002-03-27 | Novo Nordisk A/S | Acylated insulin |
| CN1163574A (zh) * | 1994-11-17 | 1997-10-29 | 伊莱利利公司 | 酰化的胰岛素类似物 |
| US6310038B1 (en) * | 1997-03-20 | 2001-10-30 | Novo Nordisk A/S | Pulmonary insulin crystals |
| AU2003208316A1 (en) * | 2002-03-13 | 2003-09-22 | Novo Nordisk A/S | Minimising body weight gain in insulin treatment |
| DK2275439T3 (da) | 2003-08-05 | 2014-05-12 | Novo Nordisk As | Hidtil ukendte insulinderivater |
| CA2531988C (en) | 2003-08-05 | 2016-06-28 | Novo Nordisk A/S | Novel insulin derivatives |
| ES2371361T3 (es) * | 2005-12-28 | 2011-12-30 | Novo Nordisk A/S | Composiciones que comprenden una insulina acilada y zinc y método de producción de dichas composiciones. |
| JP5721432B2 (ja) | 2007-08-15 | 2015-05-20 | ノボ・ノルデイスク・エー／エス | アミノ酸含有アルキレングリコール反復単位を含むアシル部を有するインスリン |
| HUE032284T2 (en) * | 2008-03-18 | 2017-09-28 | Novo Nordisk As | Protease-stabilized, acylated insulin analogues |
| US8935928B2 (en) * | 2011-10-10 | 2015-01-20 | Lockheed Martin Corporation | Integrated air-cycle refrigeration and power generation system |
| KR20140104994A (ko) | 2011-12-15 | 2014-08-29 | 샹하이 헨그루이 파마수티컬 컴퍼니 리미티드 | 인간 인슐린 유사체 및 이의 아실화 유도체 |
| CN106496322A (zh) | 2015-09-07 | 2017-03-15 | 江苏恒瑞医药股份有限公司 | 人胰岛素或其类似物的酰化衍生物的制备方法 |
| KR20180105236A (ko) * | 2016-02-05 | 2018-09-27 | 메모리얼 슬로안-케터링 캔서 센터 | 줄기 세포-유래 외배엽 계통 전구체의 분화 방법 |
-
2017
- 2017-08-01 WO PCT/CN2017/095377 patent/WO2018024186A1/zh not_active Ceased
- 2017-08-01 CN CN201780005001.7A patent/CN108463468B/zh active Active
- 2017-08-01 US US16/320,997 patent/US10815287B2/en active Active
- 2017-08-01 CN CN202210131921.6A patent/CN114478747B/zh active Active
- 2017-08-01 TW TW106125882A patent/TWI747929B/zh active
- 2017-08-01 EP EP17836368.5A patent/EP3495384A4/en not_active Withdrawn
- 2017-08-01 JP JP2019503703A patent/JP7432361B2/ja active Active
-
2022
- 2022-04-13 JP JP2022066071A patent/JP2022095872A/ja active Pending
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