JP2022509568A5 - - Google Patents
Info
- Publication number
- JP2022509568A5 JP2022509568A5 JP2021552785A JP2021552785A JP2022509568A5 JP 2022509568 A5 JP2022509568 A5 JP 2022509568A5 JP 2021552785 A JP2021552785 A JP 2021552785A JP 2021552785 A JP2021552785 A JP 2021552785A JP 2022509568 A5 JP2022509568 A5 JP 2022509568A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- gip
- peptide analog
- fatty acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18209896.2 | 2018-12-03 | ||
| EP18209896 | 2018-12-03 | ||
| EP19176739 | 2019-05-27 | ||
| EP19176739.1 | 2019-05-27 | ||
| PCT/EP2019/083506 WO2020115048A1 (en) | 2018-12-03 | 2019-12-03 | Modified gip peptide analogues |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022509568A JP2022509568A (ja) | 2022-01-20 |
| JP2022509568A5 true JP2022509568A5 (enExample) | 2022-12-07 |
| JP7605747B2 JP7605747B2 (ja) | 2024-12-24 |
Family
ID=68731999
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021552785A Active JP7605747B2 (ja) | 2018-12-03 | 2019-12-03 | 修飾されたｇｉｐペプチド類似体 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US12187773B2 (enExample) |
| EP (2) | EP3891173A1 (enExample) |
| JP (1) | JP7605747B2 (enExample) |
| KR (2) | KR20260011770A (enExample) |
| CN (3) | CN121449721A (enExample) |
| AU (2) | AU2019391300B2 (enExample) |
| BR (1) | BR112021010447A2 (enExample) |
| CA (1) | CA3121043A1 (enExample) |
| IL (1) | IL283385A (enExample) |
| MX (1) | MX2021006505A (enExample) |
| SG (1) | SG11202105586YA (enExample) |
| WO (2) | WO2020115048A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20250346647A2 (en) * | 2019-12-03 | 2025-11-13 | Antag Therapeutics Aps | Optimized GIP Peptide Analogues |
| CN116133677B (zh) * | 2020-07-06 | 2026-04-17 | 鸿绪生物医药科技（北京）有限公司 | 新型多肽制剂及其治疗用途 |
| US20230263896A1 (en) * | 2020-07-06 | 2023-08-24 | Vitalixir (Beijing) Co., Ltd | Novel polypeptide and therapeutic use thereof |
| CA3204051A1 (en) | 2021-01-20 | 2022-07-28 | Brian Lian | Compositions and methods for the treatment of metabolic and liver disorders |
| CA3221661A1 (en) * | 2021-06-10 | 2022-12-15 | Alexander HOVARD SPARRE-ULRICH | Treatment of obesity and obesity-related disorders |
| JP7642830B2 (ja) | 2021-09-15 | 2025-03-10 | バイキング・セラピューティクス・インコーポレイテッド | 代謝及び肝臓障害の処置のための組成物及び方法 |
| WO2023139106A2 (en) | 2022-01-18 | 2023-07-27 | Novo Nordisk A/S | Long-acting gipr antagonists |
| EP4556487A1 (en) * | 2022-07-13 | 2025-05-21 | Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. | Glp-1/gip dual agonist, and preparation method therefor and use thereof |
| CN118255864A (zh) * | 2022-12-26 | 2024-06-28 | 杭州中美华东制药有限公司 | Gip受体激动剂及其用途 |
| CN116120425A (zh) * | 2022-12-27 | 2023-05-16 | 南京赛诺生物技术有限公司 | 一种glp-1/gip受体双重激动剂及其应用 |
| GB202302686D0 (en) * | 2023-02-24 | 2023-04-12 | Imperial College Innovations Ltd | Novel compounds |
| CN121464151A (zh) * | 2023-02-24 | 2026-02-03 | Ip2Ipo创新有限公司 | 化合物 |
| EP4687947A1 (en) * | 2023-04-05 | 2026-02-11 | Antag Therapeutics ApS | Gip activity modulators and orthostatic intolerance |
| TW202529796A (zh) * | 2023-11-22 | 2025-08-01 | 大陸商杭州中美華東製藥有限公司 | Glp-1r/gipr雙標靶激動劑在製備動物藥的用途 |
| WO2025154021A1 (en) * | 2024-01-19 | 2025-07-24 | Takeda Pharmaceutical Company Limited | Improved gip receptor agonist peptide compounds and uses thereof |
| WO2025154020A1 (en) * | 2024-01-19 | 2025-07-24 | Takeda Pharmaceutical Company Limited | Improved gip receptor agonist peptide compounds and uses thereof |
| WO2025176999A2 (en) * | 2024-02-23 | 2025-08-28 | Ip2Ipo Innovations Limited | Novel compounds |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5869602A (en) | 1995-03-17 | 1999-02-09 | Novo Nordisk A/S | Peptide derivatives |
| US5745335A (en) | 1996-06-27 | 1998-04-28 | Gennum Corporation | Multi-layer film capacitor structures and method |
| US6384016B1 (en) | 1998-03-13 | 2002-05-07 | Novo Nordisk A/S | Stabilized aqueous peptide solutions |
| US6458924B2 (en) | 1996-08-30 | 2002-10-01 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
| IL128332A0 (en) | 1996-08-30 | 2000-01-31 | Novo Nordisk As | GLP-1 derivatives |
| US6268343B1 (en) | 1996-08-30 | 2001-07-31 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
| WO1998024464A1 (en) | 1996-12-03 | 1998-06-11 | Trustees Of Boston University | Specific antagonists for glucose-dependent insulinotropic polypeptide (gip) |
| ATE197408T1 (de) | 1998-01-30 | 2000-11-11 | Novo Nordisk As | Eine injektionsspritze |
| JP2003522099A (ja) | 1998-02-27 | 2003-07-22 | ノボ ノルディスク アクティーゼルスカブ | 遅延作用プロファイルを有するｇｌｐ−１のｇｌｐ−１誘導体及びエキセンジン |
| EP1119625B1 (en) | 1998-10-07 | 2005-06-29 | Medical College Of Georgia Research Institute, Inc. | Glucose-dependent insulinotropic peptide for use as an osteotropic hormone |
| CZ295044B6 (cs) | 1998-12-07 | 2005-05-18 | Societe De Conseils De Recherches Et D'application | Analogy GLP-1, mající kyselinu aminoizomáselnou na pozicích 8 a 35, jejich použití a farmaceutické prostředky je obsahující |
| US6921748B1 (en) | 1999-03-29 | 2005-07-26 | Uutech Limited | Analogs of gastric inhibitory polypeptide and their use for treatment of diabetes |
| GB0404124D0 (en) | 2004-02-25 | 2004-03-31 | Univ Ulster | Antagonists of GIP |
| US20050272652A1 (en) | 1999-03-29 | 2005-12-08 | Gault Victor A | Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity |
| IL155812A0 (en) | 2000-12-07 | 2003-12-23 | Lilly Co Eli | Glp-1 fusion proteins |
| WO2003028298A2 (en) | 2001-09-21 | 2003-04-03 | Koninklijke Philips Electronics N.V. | No specific control module? use less specific one |
| US20030232761A1 (en) | 2002-03-28 | 2003-12-18 | Hinke Simon A. | Novel analogues of glucose-dependent insulinotropic polypeptide |
| WO2004067548A2 (en) | 2003-01-31 | 2004-08-12 | Theratechnologies Inc. | Chemically modified metabolites of regulatory peptides and methods of producing and using same |
| US8263545B2 (en) * | 2005-02-11 | 2012-09-11 | Amylin Pharmaceuticals, Inc. | GIP analog and hybrid polypeptides with selectable properties |
| KR20070115947A (ko) | 2005-02-11 | 2007-12-06 | 아밀린 파마슈티칼스, 인크. | 선택가능한 특성들을 가지는 ｇｉｐ 유사체 및 하이브리드폴리펩타이드 |
| TWI362392B (en) | 2005-03-18 | 2012-04-21 | Novo Nordisk As | Acylated glp-1 compounds |
| WO2007109354A2 (en) | 2006-03-21 | 2007-09-27 | Amylin Pharmaceuticals, Inc. | Peptide-peptidase inhibitor conjugates and methods of using same |
| WO2010016936A1 (en) | 2008-08-07 | 2010-02-11 | Ipsen Pharma S.A.S. | Pharmaceutical compositions of analogues of glucose-dependent insulinotropic polypeptide |
| KR20110043687A (ko) | 2008-08-07 | 2011-04-27 | 입센 파마 에스.에이.에스 | 포도당 의존적인 인슐린 분비 자극성 폴리펩타이드의 절단형 유사체 |
| WO2010016940A2 (en) | 2008-08-07 | 2010-02-11 | Ipsen Pharma S.A.S. | Analogues of glucose-dependent insulinotropic polypeptide |
| AU2009280021B2 (en) | 2008-08-07 | 2012-10-04 | Ipsen Pharma S.A.S. | Analogues of glucose-dependent insulinotropic polypeptide (GIP) modified at N-terminal |
| ES2574835T3 (es) | 2008-08-07 | 2016-06-22 | Ipsen Pharma S.A.S. | Análogos del polipéptido insulinotrópico dependiente de glucosa |
| US9023986B2 (en) | 2010-10-25 | 2015-05-05 | Hoffmann-La Roche Inc. | Glucose-dependent insulinotropic peptide analogs |
| WO2012088379A2 (en) | 2010-12-22 | 2012-06-28 | Marcadia Biotech, Inc. | Methods for treating metabolic disorders and obesity with gip and glp-1 receptor-active glucagon-based peptides |
| US9453062B2 (en) | 2011-06-10 | 2016-09-27 | Beijing Hanmi Pharmaceutical Co., Ltd. | Glucose dependent insulinotropic polypeptide analogs, pharmaceutical compositions and use thereof |
| CN104583232B (zh) * | 2012-06-21 | 2018-04-13 | 印第安纳大学研究及科技有限公司 | 展现gip受体活性的胰高血糖素类似物 |
| TW201625668A (zh) * | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物 |
| TW201625669A (zh) * | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑 |
| ES2685987T3 (es) | 2014-09-05 | 2018-10-15 | University Of Copenhagen | Análogos de péptidos gip |
| KR102620911B1 (ko) | 2014-10-29 | 2024-01-05 | 질랜드 파마 에이/에스 | Gip 효능제 화합물 및 방법 |
| WO2016205488A1 (en) | 2015-06-17 | 2016-12-22 | The California Institute For Biomedical Research | Modified therapeutic agents and compositions thereof |
| EP3526242A1 (en) | 2016-10-12 | 2019-08-21 | University of Copenhagen | Peptide dual agonists of gipr and glp2r |
| US20190352335A1 (en) * | 2016-12-19 | 2019-11-21 | Hanmi Pharm. Co., Ltd. | Brain targeting long-acting protein conjugate |
| CN110099694A (zh) | 2016-12-26 | 2019-08-06 | 花王株式会社 | 低体温改善剂 |
| WO2018124010A1 (ja) | 2016-12-26 | 2018-07-05 | 花王株式会社 | 認知機能改善剤 |
| JP7165495B2 (ja) | 2016-12-26 | 2022-11-04 | 花王株式会社 | 運動調節機能向上剤 |
| KR102743887B1 (ko) * | 2017-05-31 | 2024-12-19 | 유니버시티 오브 코펜하겐 | 장기-작용성 gip 펩타이드 유사체 |
-
2019
- 2019-12-03 SG SG11202105586YA patent/SG11202105586YA/en unknown
- 2019-12-03 CN CN202511386365.7A patent/CN121449721A/zh active Pending
- 2019-12-03 EP EP19812788.8A patent/EP3891173A1/en active Pending
- 2019-12-03 US US17/298,444 patent/US12187773B2/en active Active
- 2019-12-03 MX MX2021006505A patent/MX2021006505A/es unknown
- 2019-12-03 CN CN202511386362.3A patent/CN121449720A/zh active Pending
- 2019-12-03 KR KR1020257043349A patent/KR20260011770A/ko active Pending
- 2019-12-03 EP EP19812789.6A patent/EP3891174A1/en active Pending
- 2019-12-03 CA CA3121043A patent/CA3121043A1/en active Pending
- 2019-12-03 AU AU2019391300A patent/AU2019391300B2/en active Active
- 2019-12-03 JP JP2021552785A patent/JP7605747B2/ja active Active
- 2019-12-03 CN CN201980090373.3A patent/CN113366014B/zh active Active
- 2019-12-03 BR BR112021010447-0A patent/BR112021010447A2/pt unknown
- 2019-12-03 WO PCT/EP2019/083506 patent/WO2020115048A1/en not_active Ceased
- 2019-12-03 US US17/298,512 patent/US12297250B2/en active Active
- 2019-12-03 KR KR1020217019677A patent/KR102906485B1/ko active Active
- 2019-12-03 WO PCT/EP2019/083509 patent/WO2020115049A1/en not_active Ceased
-
2021
- 2021-05-24 IL IL283385A patent/IL283385A/en unknown
-
2025
- 2025-03-31 US US19/096,393 patent/US20250376499A1/en active Pending
- 2025-09-24 AU AU2025237957A patent/AU2025237957A1/en active Pending
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