IL283385A - Modified gip peptide analogues - Google Patents
Modified gip peptide analoguesInfo
- Publication number
- IL283385A IL283385A IL283385A IL28338521A IL283385A IL 283385 A IL283385 A IL 283385A IL 283385 A IL283385 A IL 283385A IL 28338521 A IL28338521 A IL 28338521A IL 283385 A IL283385 A IL 283385A
- Authority
- IL
- Israel
- Prior art keywords
- gip peptide
- different analogs
- analogs
- different
- gip
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/645—Secretins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18209896 | 2018-12-03 | ||
| EP19176739 | 2019-05-27 | ||
| PCT/EP2019/083506 WO2020115048A1 (en) | 2018-12-03 | 2019-12-03 | Modified gip peptide analogues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL283385A true IL283385A (en) | 2021-07-29 |
Family
ID=68731999
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL283385A IL283385A (en) | 2018-12-03 | 2021-05-24 | Modified gip peptide analogues |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US12187773B2 (enExample) |
| EP (2) | EP3891173A1 (enExample) |
| JP (1) | JP7605747B2 (enExample) |
| CN (1) | CN113366014B (enExample) |
| AU (2) | AU2019391300B2 (enExample) |
| BR (1) | BR112021010447A2 (enExample) |
| CA (1) | CA3121043A1 (enExample) |
| IL (1) | IL283385A (enExample) |
| MX (1) | MX2021006505A (enExample) |
| SG (1) | SG11202105586YA (enExample) |
| WO (2) | WO2020115049A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20250346647A2 (en) * | 2019-12-03 | 2025-11-13 | Antag Therapeutics Aps | Optimized GIP Peptide Analogues |
| CN116133677A (zh) * | 2020-07-06 | 2023-05-16 | 鸿绪生物医药科技（北京）有限公司 | 新型多肽制剂及其治疗用途 |
| EP4177263A4 (en) * | 2020-07-06 | 2024-11-13 | Vitalixir (Beijing) Co., Ltd | NEW POLYPEPTIDE AND ITS THERAPEUTIC USE |
| KR20240118914A (ko) | 2021-01-20 | 2024-08-05 | 바이킹 테라퓨틱스 인코포레이티드 | 대사 및 간 질환 치료를 위한 조성물 및 방법 |
| JP2024521398A (ja) * | 2021-06-10 | 2024-05-31 | アンタグ セラピューティクス エーピーエス | 肥満及び肥満関連障害の治療 |
| WO2023044290A1 (en) | 2021-09-15 | 2023-03-23 | Viking Therapeutics, Inc. | Compositions and methods for the treatment of metabolic and liver disorders |
| WO2023139106A2 (en) | 2022-01-18 | 2023-07-27 | Novo Nordisk A/S | Long-acting gipr antagonists |
| CR20250051A (es) * | 2022-07-13 | 2025-03-18 | Hangzhou Zhongmeihuadong Pharmaceutical Co Ltd | Agonista dual de glp-1/gip, método de preparación y uso del mismo |
| CN118255864A (zh) * | 2022-12-26 | 2024-06-28 | 杭州中美华东制药有限公司 | Gip受体激动剂及其用途 |
| GB202302686D0 (en) * | 2023-02-24 | 2023-04-12 | Imperial College Innovations Ltd | Novel compounds |
| WO2024209050A1 (en) * | 2023-04-05 | 2024-10-10 | Antag Therapeutics Aps | Gip activity modulators and orthostatic intolerance |
| TW202529796A (zh) * | 2023-11-22 | 2025-08-01 | 大陸商杭州中美華東製藥有限公司 | Glp-1r/gipr雙標靶激動劑在製備動物藥的用途 |
| WO2025154021A1 (en) * | 2024-01-19 | 2025-07-24 | Takeda Pharmaceutical Company Limited | Improved gip receptor agonist peptide compounds and uses thereof |
| WO2025154020A1 (en) * | 2024-01-19 | 2025-07-24 | Takeda Pharmaceutical Company Limited | Improved gip receptor agonist peptide compounds and uses thereof |
| WO2025176999A2 (en) * | 2024-02-23 | 2025-08-28 | Ip2Ipo Innovations Limited | Novel compounds |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5869602A (en) | 1995-03-17 | 1999-02-09 | Novo Nordisk A/S | Peptide derivatives |
| US5745335A (en) | 1996-06-27 | 1998-04-28 | Gennum Corporation | Multi-layer film capacitor structures and method |
| JP3149958B2 (ja) | 1996-08-30 | 2001-03-26 | ノボ ノルディスク アクティーゼルスカブ | Ｇｌｐ―１誘導体 |
| US6458924B2 (en) | 1996-08-30 | 2002-10-01 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
| US6268343B1 (en) | 1996-08-30 | 2001-07-31 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
| WO1998024464A1 (en) | 1996-12-03 | 1998-06-11 | Trustees Of Boston University | Specific antagonists for glucose-dependent insulinotropic polypeptide (gip) |
| DE69900026T2 (de) | 1998-01-30 | 2001-05-10 | Novo Nordisk As | Eine injektionsspritze |
| JP2003522099A (ja) | 1998-02-27 | 2003-07-22 | ノボ ノルディスク アクティーゼルスカブ | 遅延作用プロファイルを有するｇｌｐ−１のｇｌｐ−１誘導体及びエキセンジン |
| DE69918070T2 (de) | 1998-03-13 | 2005-08-25 | Novo Nordisk A/S | Stabilisierte, wässrige Glukagonlösungen, enthaltend Detergenzien |
| JP2002526554A (ja) | 1998-10-07 | 2002-08-20 | メディカル カレッジ オブ ジョージア リサーチ インスティチュート，インコーポレイテッド | 骨親和性ホルモンとして用いられるグルコース依存性インスリン親和性ペプチド |
| WO2000034331A2 (en) | 1998-12-07 | 2000-06-15 | Societe De Conseils De Recherches Et D'applications Scientifiques Sas | Analogues of glp-1 |
| ATE272650T1 (de) | 1999-03-29 | 2004-08-15 | Uutech Ltd | Analoge des magensaft inhibierenden peptides und ihre verwendung für die behandlung von diabetes |
| GB0404124D0 (en) | 2004-02-25 | 2004-03-31 | Univ Ulster | Antagonists of GIP |
| US20050272652A1 (en) * | 1999-03-29 | 2005-12-08 | Gault Victor A | Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity |
| WO2002046227A2 (en) | 2000-12-07 | 2002-06-13 | Eli Lilly And Company | Glp-1 fusion proteins |
| DE60216629T2 (de) | 2001-09-21 | 2007-10-11 | Koninklijke Philips Electronics N.V. | Gibt es kein spezifisches kontrollmodul? benutzen sie eines das weniger spezifisch ist |
| US20030232761A1 (en) | 2002-03-28 | 2003-12-18 | Hinke Simon A. | Novel analogues of glucose-dependent insulinotropic polypeptide |
| US20050059605A1 (en) | 2003-01-31 | 2005-03-17 | Krishna Peri | Chemically modified metabolites of regulatory peptides and methods of producing and using same |
| US8263545B2 (en) * | 2005-02-11 | 2012-09-11 | Amylin Pharmaceuticals, Inc. | GIP analog and hybrid polypeptides with selectable properties |
| EP2390264A1 (en) | 2005-02-11 | 2011-11-30 | Amylin Pharmaceuticals Inc. | GIP analog and hybrid polypeptides with selectable propperties |
| TWI372629B (en) | 2005-03-18 | 2012-09-21 | Novo Nordisk As | Acylated glp-1 compounds |
| WO2007109354A2 (en) | 2006-03-21 | 2007-09-27 | Amylin Pharmaceuticals, Inc. | Peptide-peptidase inhibitor conjugates and methods of using same |
| EP2987805A3 (en) | 2008-08-07 | 2016-04-13 | Ipsen Pharma S.A.S. | Analogues of glucose-dependent insulinotropic polypeptide |
| KR20110043688A (ko) | 2008-08-07 | 2011-04-27 | 입센 파마 에스.에이.에스 | 포도당 의존적인 인슐린 분비 자극성 폴리펩타이드 유사체 |
| PT2320923E (pt) | 2008-08-07 | 2015-02-24 | Ipsen Pharma Sas | Análogos truncados de polipéptido insulinotrópico dependente de glucose |
| EA020091B1 (ru) | 2008-08-07 | 2014-08-29 | Ипсен Фарма С.А.С. | Аналоги глюкозозависимого инсулинотропного полипептида (gip), модифицированные по n-концу |
| WO2010016936A1 (en) | 2008-08-07 | 2010-02-11 | Ipsen Pharma S.A.S. | Pharmaceutical compositions of analogues of glucose-dependent insulinotropic polypeptide |
| US9023986B2 (en) | 2010-10-25 | 2015-05-05 | Hoffmann-La Roche Inc. | Glucose-dependent insulinotropic peptide analogs |
| AR084558A1 (es) | 2010-12-22 | 2013-05-22 | Marcadia Biotech | Metodos para tratar trastornos metabolicos y obesidad con peptidos basados en glucagon activos para el receptor de peptido insulinotropico dependiente de glucosa (gip)/peptido-1 similar al glucagon (glp-1) |
| EP2718317B1 (en) * | 2011-06-10 | 2018-11-14 | Beijing Hanmi Pharmaceutical Co., Ltd. | Glucose dependent insulinotropic polypeptide analogs, pharmaceutical compositions and use thereof |
| US9340600B2 (en) * | 2012-06-21 | 2016-05-17 | Indiana University Research And Technology Corporation | Glucagon analogs exhibiting GIP receptor activity |
| TW201625668A (zh) * | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物 |
| TW201625669A (zh) * | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑 |
| US10968266B2 (en) | 2014-09-05 | 2021-04-06 | University Of Copenhagen | GIP peptide analogues |
| EP3212218B1 (en) | 2014-10-29 | 2021-06-30 | Zealand Pharma A/S | Gip agonist compounds and methods |
| CN107921098A (zh) | 2015-06-17 | 2018-04-17 | 加州生物医学研究所 | 修饰的治疗剂及其组合物 |
| US10774127B2 (en) | 2016-10-12 | 2020-09-15 | University Of Copenhagen | Peptide dual agonists of GIPR and GLP2R |
| CN110312532A (zh) * | 2016-12-19 | 2019-10-08 | 韩美药品株式会社 | 脑靶向长效蛋白质缀合物 |
| US11319369B2 (en) | 2016-12-26 | 2022-05-03 | Kao Corporation | Motor control function improving agent |
| JP7165496B2 (ja) | 2016-12-26 | 2022-11-04 | 花王株式会社 | 認知機能改善剤 |
| US20190330332A1 (en) | 2016-12-26 | 2019-10-31 | Kao Corporation | Hypothermia Ameliorating Agent |
| KR102743887B1 (ko) | 2017-05-31 | 2024-12-19 | 유니버시티 오브 코펜하겐 | 장기-작용성 gip 펩타이드 유사체 |
-
2019
- 2019-12-03 EP EP19812788.8A patent/EP3891173A1/en active Pending
- 2019-12-03 MX MX2021006505A patent/MX2021006505A/es unknown
- 2019-12-03 CA CA3121043A patent/CA3121043A1/en active Pending
- 2019-12-03 WO PCT/EP2019/083509 patent/WO2020115049A1/en not_active Ceased
- 2019-12-03 AU AU2019391300A patent/AU2019391300B2/en active Active
- 2019-12-03 BR BR112021010447-0A patent/BR112021010447A2/pt unknown
- 2019-12-03 WO PCT/EP2019/083506 patent/WO2020115048A1/en not_active Ceased
- 2019-12-03 EP EP19812789.6A patent/EP3891174A1/en active Pending
- 2019-12-03 US US17/298,444 patent/US12187773B2/en active Active
- 2019-12-03 CN CN201980090373.3A patent/CN113366014B/zh active Active
- 2019-12-03 SG SG11202105586YA patent/SG11202105586YA/en unknown
- 2019-12-03 US US17/298,512 patent/US12297250B2/en active Active
- 2019-12-03 JP JP2021552785A patent/JP7605747B2/ja active Active
-
2021
- 2021-05-24 IL IL283385A patent/IL283385A/en unknown
-
2025
- 2025-03-31 US US19/096,393 patent/US20250376499A1/en active Pending
- 2025-09-24 AU AU2025237957A patent/AU2025237957A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US12297250B2 (en) | 2025-05-13 |
| US20220025010A1 (en) | 2022-01-27 |
| MX2021006505A (es) | 2021-10-01 |
| BR112021010447A2 (pt) | 2021-08-24 |
| CN113366014B (zh) | 2025-10-21 |
| WO2020115049A1 (en) | 2020-06-11 |
| US20250376499A1 (en) | 2025-12-11 |
| CA3121043A1 (en) | 2020-06-11 |
| CN113366014A (zh) | 2021-09-07 |
| SG11202105586YA (en) | 2021-06-29 |
| AU2019391300A1 (en) | 2021-07-01 |
| AU2025237957A1 (en) | 2025-10-16 |
| EP3891174A1 (en) | 2021-10-13 |
| AU2019391300B2 (en) | 2025-06-26 |
| JP7605747B2 (ja) | 2024-12-24 |
| EP3891173A1 (en) | 2021-10-13 |
| US12187773B2 (en) | 2025-01-07 |
| KR20210102911A (ko) | 2021-08-20 |
| JP2022509568A (ja) | 2022-01-20 |
| US20220298218A1 (en) | 2022-09-22 |
| WO2020115048A1 (en) | 2020-06-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL283385A (en) | Modified gip peptide analogues | |
| IL279827A (en) | Gip/glp1 co-agonist compounds | |
| EP3870593A4 (en) | NUCLEOTIDE ANALOGUES | |
| DK3778621T3 (da) | Peptidsyntesefremgangsmåde | |
| PL3727460T3 (pl) | Bicykliczne ligandy peptydowe swoiste wobec epha2 | |
| IL283445A (en) | Jettable composition | |
| DK4122954T3 (da) | Novel GLP-1-analoger | |
| MA46180A (fr) | Analogues de l'amyline | |
| EP3802852A4 (en) | MANIPULATED CYCLIC PEPTIDES | |
| EP3720865C0 (en) | NOVEL SPIROBICYCLIC ANALOGUES | |
| SI3794166T1 (sl) | Izboljšanje elektrorafiniranja bakra | |
| IL282330A (en) | Therapeutic compounds | |
| IL282114A (en) | Processes for preparing functionalized cyclooctenes | |
| EP3710462A4 (en) | BRARTEMICIN ANALOGA | |
| EP3768272A4 (en) | JAK HEMMER | |
| DK3840767T5 (da) | Peptider | |
| IL283673A (en) | Deuterated analogs of acetyl-leucine | |
| SI3512495T1 (sl) | Formulacije prostaciklinskih analogov | |
| EP3914606A4 (en) | CYCLIC PEPTIDE | |
| IL285119A (en) | Use of spiropidion | |
| IL280891A (en) | Erbumine salt of treprostinil | |
| EP3906225C0 (en) | Pantothenamide analogues | |
| EP3792349A4 (en) | Peptide macrocyclase | |
| EP3861236A4 (en) | BELLOWS | |
| MA52226A (fr) | Nouveaux analogues de glp-1 |