JP2024521444A5 - - Google Patents
Info
- Publication number
- JP2024521444A5 JP2024521444A5 JP2023576064A JP2023576064A JP2024521444A5 JP 2024521444 A5 JP2024521444 A5 JP 2024521444A5 JP 2023576064 A JP2023576064 A JP 2023576064A JP 2023576064 A JP2023576064 A JP 2023576064A JP 2024521444 A5 JP2024521444 A5 JP 2024521444A5
- Authority
- JP
- Japan
- Prior art keywords
- item
- cancer
- sequence
- rna
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163209271P | 2021-06-10 | 2021-06-10 | |
| US63/209,271 | 2021-06-10 | ||
| US202263311923P | 2022-02-18 | 2022-02-18 | |
| US63/311,923 | 2022-02-18 | ||
| PCT/US2022/033091 WO2022261490A2 (en) | 2021-06-10 | 2022-06-10 | Circular rna compositions and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024521444A JP2024521444A (ja) | 2024-05-31 |
| JP2024521444A5 true JP2024521444A5 (OSRAM) | 2025-06-06 |
Family
ID=83081188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023576064A Pending JP2024521444A (ja) | 2021-06-10 | 2022-06-10 | 環状ｒｎａ組成物及び方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20250283073A1 (OSRAM) |
| EP (1) | EP4352234A2 (OSRAM) |
| JP (1) | JP2024521444A (OSRAM) |
| KR (1) | KR20240019791A (OSRAM) |
| AU (1) | AU2022288705A1 (OSRAM) |
| BR (1) | BR112023025515A2 (OSRAM) |
| CA (1) | CA3219932A1 (OSRAM) |
| IL (1) | IL308746A (OSRAM) |
| MX (1) | MX2023014702A (OSRAM) |
| TW (1) | TW202317767A (OSRAM) |
| WO (1) | WO2022261490A2 (OSRAM) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK4271818T3 (da) | 2021-09-17 | 2024-11-04 | Flagship Pioneering Innovations Vi Llc | Sammensætninger og fremgangsmåder til fremstilling af cirkulære polyribonukleotider |
| CN114214237B (zh) * | 2021-12-23 | 2023-06-16 | 南京大学 | 一种洗脱细胞表面吸附纳米颗粒的方法 |
| TW202334412A (zh) * | 2022-01-11 | 2023-09-01 | 北京大學 | 針對 sars-cov-2 變體的環狀 rna 疫苗及其使用方法 |
| CA3241143A1 (en) * | 2022-01-21 | 2023-07-27 | Allen T. HORHOTA | Systemic administration of circular rna polynucleotides encoding muscle proteins or protein complexes |
| WO2023182948A1 (en) * | 2022-03-21 | 2023-09-28 | Bio Adventure Co., Ltd. | Internal ribosome entry site (ires), plasmid vector and circular mrna for enhancing protein expression |
| US12297285B2 (en) * | 2022-06-24 | 2025-05-13 | Orna Therapeutics, Inc. | Circular RNA encoding chimeric antigen receptors targeting BCMA |
| CN116064531B (zh) * | 2022-09-07 | 2024-04-02 | 昆明理工大学 | 一种抑制cvb5病毒复制的长链非编码rna及应用 |
| WO2024102677A1 (en) | 2022-11-08 | 2024-05-16 | Orna Therapeutics, Inc. | Circular rna compositions |
| EP4634390A2 (en) | 2022-12-15 | 2025-10-22 | Orna Therapeutics, Inc. | Circular rna compositions and methods |
| WO2024192422A1 (en) | 2023-03-15 | 2024-09-19 | Flagship Pioneering Innovations Vi, Llc | Immunogenic compositions and uses thereof |
| AU2024235803A1 (en) | 2023-03-15 | 2025-09-25 | Flagship Pioneering Innovations Vi, Llc | Compositions comprising polyribonucleotides and uses thereof |
| KR20240159310A (ko) * | 2023-04-28 | 2024-11-05 | 주식회사 메디치바이오 | 신규한 이온화지질을 이용한 지질나노입자 조성물 |
| WO2024205657A2 (en) * | 2023-03-29 | 2024-10-03 | Orna Therapeutics, Inc. | Lipids and lipid nanoparticle compositions for delivering polynucleotides |
| JP2026512425A (ja) | 2023-03-30 | 2026-04-16 | オーエスイー・イミュノセラピューティクス | 免疫細胞増強分子の発現のための活性化免疫細胞に標的化された脂質ベースのナノ粒子及びその使用 |
| EP4687990A1 (en) | 2023-03-30 | 2026-02-11 | Ose Immunotherapeutics | Method of synthesis of targeted lipid nanoparticle and uses thereof |
| WO2024220752A2 (en) | 2023-04-19 | 2024-10-24 | Sail Biomedicines, Inc. | Rna therapeutic compositions |
| EP4698150A1 (en) | 2023-04-19 | 2026-02-25 | Sail Biomedicines, Inc. | Delivery of polynucleotides from lipid nanoparticles comprising rna and ionizable lipids |
| WO2024220712A2 (en) | 2023-04-19 | 2024-10-24 | Sail Biomedicines, Inc. | Vaccine compositions |
| AU2024269222A1 (en) | 2023-05-05 | 2025-10-09 | Orna Therapeutics, Inc. | Circular rna compositions and methods |
| AU2024279278A1 (en) | 2023-05-31 | 2025-12-18 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| WO2025006613A1 (en) * | 2023-06-27 | 2025-01-02 | Hopewell Therapeutics, Inc. | Lipid nanoparticles for cancer immunotherapy |
| WO2025007148A1 (en) | 2023-06-30 | 2025-01-02 | Orna Therapeutics, Inc. | Polymer lipid nanoparticle compositions for delivering circular polynucleotides |
| WO2025036467A1 (en) * | 2023-08-17 | 2025-02-20 | Wuhan University | Circular rna with increased stability and expression |
| WO2025049690A1 (en) | 2023-08-29 | 2025-03-06 | Orna Therapeutics, Inc. | Circular polyethylene glycol lipids |
| WO2025049959A2 (en) | 2023-09-01 | 2025-03-06 | Renagade Therapeutics Management Inc. | Gene editing systems, compositions, and methods for treatment of vexas syndrome |
| WO2025101501A1 (en) | 2023-11-07 | 2025-05-15 | Orna Therapeutics, Inc. | Circular rna compositions |
| WO2025106930A1 (en) | 2023-11-17 | 2025-05-22 | Sail Biomedicines, Inc. | Circular polyribonucleotides encoding glucagon-like peptide 2 (glp-2) and uses thereof |
| WO2025106915A1 (en) | 2023-11-17 | 2025-05-22 | Sail Biomedicines, Inc. | Circular polyribonucleotides encoding glucagon-like peptide 1 (glp-1) and uses thereof |
| WO2025117969A1 (en) | 2023-12-01 | 2025-06-05 | Orna Therapeutics, Inc. | Process for manufacturing lipid nanoparticles |
| WO2025128871A2 (en) | 2023-12-13 | 2025-06-19 | Renagade Therapeutics Management Inc. | Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents |
| WO2025133115A1 (en) | 2023-12-21 | 2025-06-26 | Ose Immunotherapeutics | Lipid-based nanoparticles comprising il-35 |
| WO2025149040A1 (zh) * | 2024-01-11 | 2025-07-17 | 深圳近邻生物科技有限公司 | 一种通用的且无"scar"的RNA环化方法 |
| WO2025155753A2 (en) | 2024-01-17 | 2025-07-24 | Renagade Therapeutics Management Inc. | Improved gene editing system, guides, and methods |
| WO2025166238A1 (en) | 2024-01-31 | 2025-08-07 | Orna Therapeutics, Inc. | Fast-shedding polyethylene glycol lipids |
| WO2025179198A1 (en) | 2024-02-23 | 2025-08-28 | Sail Biomedicines, Inc. | Circular polyribonucleotides and unmodified linear rnas with reduced immunogenicity |
| WO2025218812A1 (en) * | 2024-04-19 | 2025-10-23 | Shanghai Circode Biomed Co., Ltd. | Novel internal ribosome entry sites and uses thereof |
| WO2025250751A1 (en) | 2024-05-31 | 2025-12-04 | Orna Therapeutics, Inc. | Circular rna compositions and methods |
| CN118703488A (zh) * | 2024-06-20 | 2024-09-27 | 毕昇(北京)生物科技有限公司 | 一种环状rna的纯化方法 |
| WO2026003582A2 (en) | 2024-06-27 | 2026-01-02 | Axelyf ehf. | Lipids and lipid nanoparticles |
| WO2026006593A1 (en) | 2024-06-28 | 2026-01-02 | Orna Therapeutics, Inc. | Synthetic internal ribosome entry sites |
| WO2026072709A1 (en) | 2024-09-25 | 2026-04-02 | Orna Therapeutics, Inc. | Chimeric antigen receptors targeting bcma |
| WO2026068705A1 (en) | 2024-09-26 | 2026-04-02 | Ose Immunotherapeutics | Lipid-based nanoparticles comprising non-glycosylated fc domains and uses thereof |
| GB202415784D0 (en) * | 2024-10-25 | 2024-12-11 | Rnavate Ltd | Methods for purifying circular ribonucleic acid (RNA) |
| WO2026093414A1 (en) | 2024-10-30 | 2026-05-07 | Ose Immunotherapeutics | Lipid-based nanoparticles comprising membrane il-35 |
| WO2026096738A1 (en) | 2024-10-31 | 2026-05-07 | Orna Therapeutics, Inc. | Chimeric antigen receptors targeting cd19 |
| US20260115324A1 (en) * | 2024-10-31 | 2026-04-30 | Orna Therapeutics, Inc. | Chimeric Antigen Receptors Targeting CD19 |
| CN119876152A (zh) * | 2025-02-10 | 2025-04-25 | 毕昇(北京)生物科技有限公司 | 一种环状rna、嵌合抗原受体t细胞和构建方法及应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6319494B1 (en) | 1990-12-14 | 2001-11-20 | Cell Genesys, Inc. | Chimeric chains for receptor-associated signal transduction pathways |
| IL104570A0 (en) | 1992-03-18 | 1993-05-13 | Yeda Res & Dev | Chimeric genes and cells transformed therewith |
| US6066626A (en) | 1997-10-29 | 2000-05-23 | Genzyme Corporation | Compositions and method for treating lysosomal storage disease |
| US5948902A (en) | 1997-11-20 | 1999-09-07 | South Alabama Medical Science Foundation | Antisense oligonucleotides to human serine/threonine protein phosphatase genes |
| WO2001060414A2 (en) | 2000-02-17 | 2001-08-23 | Genzyme Corporation | Genetic modification of the lung as a portal for gene delivery |
| MXPA05000511A (es) | 2001-07-12 | 2005-09-30 | Jefferson Foote | Anticuepros super humanizados. |
| US20040014194A1 (en) | 2002-03-27 | 2004-01-22 | Schering Corporation | Beta-secretase crystals and methods for preparing and using the same |
| JP5563194B2 (ja) | 2004-06-29 | 2014-07-30 | イムノコア リミテッド | 改変ｔ細胞レセプターを発現する細胞 |
| PT3083556T (pt) | 2013-12-19 | 2020-03-05 | Novartis Ag | Lípidos e composições lipídicas para a entrega de agentes ativos |
| RS63030B1 (sr) | 2015-09-17 | 2022-04-29 | Modernatx Inc | Jedinjenja i kompozicije za intracelularno isporučivanje terapeutskih sredstava |
| RS63986B1 (sr) | 2015-10-28 | 2023-03-31 | Acuitas Therapeutics Inc | Novi lipidi i lipidne formulacije nanočestica za isporuku nukleinskih kiselina |
| US11814627B2 (en) * | 2016-06-20 | 2023-11-14 | The Board Of The Leland Stanford Junior University | Circular RNAs and their use in immunomodulation |
| WO2019081383A1 (en) | 2017-10-25 | 2019-05-02 | Universität Zürich | EUCARYOTE 4 INITIATION FACTOR RECRUITMENT APTAMERS FOR ENHANCED TRANSLATION |
| US20190314291A1 (en) | 2018-01-30 | 2019-10-17 | Modernatx, Inc. | Compositions and methods for delivery of agents to immune cells |
| BR112020015796A2 (pt) | 2018-02-01 | 2021-02-09 | Trustees Of Tufts College | nanocomplexos semelhantes a lipídios e usos dos mesmos |
| WO2019191780A1 (en) | 2018-03-30 | 2019-10-03 | Arcturus Therapeutics, Inc. | Lipid particles for nucleic acid delivery |
| KR20210018323A (ko) * | 2018-06-06 | 2021-02-17 | 매사추세츠 인스티튜트 오브 테크놀로지 | 진핵 세포에서의 번역을 위한 원형 rna |
| JP7686574B2 (ja) * | 2019-05-22 | 2025-06-02 | マサチューセッツ インスティテュート オブ テクノロジー | 環状ｒｎａ組成物及び方法 |
-
2022
- 2022-06-10 AU AU2022288705A patent/AU2022288705A1/en active Pending
- 2022-06-10 JP JP2023576064A patent/JP2024521444A/ja active Pending
- 2022-06-10 KR KR1020247000046A patent/KR20240019791A/ko active Pending
- 2022-06-10 IL IL308746A patent/IL308746A/en unknown
- 2022-06-10 MX MX2023014702A patent/MX2023014702A/es unknown
- 2022-06-10 TW TW111121745A patent/TW202317767A/zh unknown
- 2022-06-10 EP EP22760801.5A patent/EP4352234A2/en active Pending
- 2022-06-10 WO PCT/US2022/033091 patent/WO2022261490A2/en not_active Ceased
- 2022-06-10 US US18/567,469 patent/US20250283073A1/en active Pending
- 2022-06-10 BR BR112023025515A patent/BR112023025515A2/pt unknown
- 2022-06-10 CA CA3219932A patent/CA3219932A1/en active Pending
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