JP2024521092A5 - - Google Patents

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Publication number
JP2024521092A5
JP2024521092A5 JP2023571661A JP2023571661A JP2024521092A5 JP 2024521092 A5 JP2024521092 A5 JP 2024521092A5 JP 2023571661 A JP2023571661 A JP 2023571661A JP 2023571661 A JP2023571661 A JP 2023571661A JP 2024521092 A5 JP2024521092 A5 JP 2024521092A5
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JP
Japan
Prior art keywords
target
salt
compound
moi
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023571661A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024521092A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/030070 external-priority patent/WO2022246086A1/en
Publication of JP2024521092A publication Critical patent/JP2024521092A/ja
Publication of JP2024521092A5 publication Critical patent/JP2024521092A5/ja
Pending legal-status Critical Current

Links

JP2023571661A 2021-05-19 2022-05-19 細胞傷害性薬剤を送達するためのｍａｔｅｓ技術を使用する抗体薬物コンジュゲート Pending JP2024521092A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163190703P 2021-05-19 2021-05-19
US63/190,703 2021-05-19
PCT/US2022/030070 WO2022246086A1 (en) 2021-05-19 2022-05-19 Antibody drug conjugates using mates technology for delivering cytotoxic agents

Publications (2)

Publication Number Publication Date
JP2024521092A JP2024521092A (ja) 2024-05-28
JP2024521092A5 true JP2024521092A5 (enExample) 2025-05-26

Family

ID=84141792

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023571661A Pending JP2024521092A (ja) 2021-05-19 2022-05-19 細胞傷害性薬剤を送達するためのｍａｔｅｓ技術を使用する抗体薬物コンジュゲート

Country Status (12)

Country Link
US (1) US20250108124A1 (enExample)
EP (1) EP4340859A4 (enExample)
JP (1) JP2024521092A (enExample)
KR (1) KR20240012381A (enExample)
CN (1) CN117412761A (enExample)
AU (1) AU2022277698A1 (enExample)
BR (1) BR112023023525A2 (enExample)
CA (1) CA3219550A1 (enExample)
IL (1) IL307884A (enExample)
MX (1) MX2023013270A (enExample)
PH (1) PH12023553153A1 (enExample)
WO (1) WO2022246086A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112023023506A2 (pt) * 2021-05-17 2024-01-30 Biohaven Therapeutics Ltd Composições incluindo intensificadores de terapia conjugada
WO2024226448A1 (en) * 2023-04-23 2024-10-31 Biohaven Therapeutics Ltd. Antibody-drug conjugates for delivering cytotoxic agents

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3434275A1 (en) * 2003-11-06 2019-01-30 Seattle Genetics, Inc. Assay for cancer cells based on the use of auristatin conjugates with antibodies
WO2007147901A1 (en) * 2006-06-22 2007-12-27 Novo Nordisk A/S Production of bispecific antibodies
EP2497775A1 (en) * 2011-03-11 2012-09-12 Ruprecht-Karls-Universität Heidelberg Ferrocene-based compounds and their use as ROS regulating prodrugs
CN102936281B (zh) * 2012-10-25 2013-12-25 浙江大学 一种rTRAIL突变体及其海兔毒素偶联物
US10188746B2 (en) * 2014-09-10 2019-01-29 Medimmune Limited Pyrrolobenzodiazepines and conjugates thereof
WO2016070089A2 (en) * 2014-10-31 2016-05-06 Abbvie Biotherapeutics Inc. Anti-cs1 antibodies and antibody drug conjugates
EP3991748A3 (en) * 2015-04-07 2022-08-24 Alector LLC Anti-sortilin antibodies and methods of use thereof
ES3066090T3 (en) * 2017-04-28 2026-05-11 Ajinomoto Co Inc Compound having substance that has affinity for soluble protein, cleavable moiety, and reactive group, or salt thereof
WO2019241609A1 (en) * 2018-06-15 2019-12-19 Trustees Of Boston University Polypeptide compositions and methods for site-specific targeting of therapeutic agents
EP3894427A1 (en) * 2018-12-10 2021-10-20 Genentech, Inc. Photocrosslinking peptides for site specific conjugation to fc-containing proteins
WO2021003050A2 (en) * 2019-07-03 2021-01-07 Kleo Pharmaceuticals, Inc. Cd38-binding agents and uses thereof
CN115066263A (zh) * 2019-11-18 2022-09-16 克莱奥药品有限公司 定向缀合技术

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