JP2024516073A5 - - Google Patents

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Publication number
JP2024516073A5
JP2024516073A5 JP2023557140A JP2023557140A JP2024516073A5 JP 2024516073 A5 JP2024516073 A5 JP 2024516073A5 JP 2023557140 A JP2023557140 A JP 2023557140A JP 2023557140 A JP2023557140 A JP 2023557140A JP 2024516073 A5 JP2024516073 A5 JP 2024516073A5
Authority
JP
Japan
Application number
JP2023557140A
Other languages
Japanese (ja)
Other versions
JP2024516073A (ja
JPWO2022197758A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/020482 external-priority patent/WO2022197758A1/en
Publication of JP2024516073A publication Critical patent/JP2024516073A/ja
Publication of JP2024516073A5 publication Critical patent/JP2024516073A5/ja
Publication of JPWO2022197758A5 publication Critical patent/JPWO2022197758A5/ja
Pending legal-status Critical Current

Links

JP2023557140A 2021-03-17 2022-03-16 血漿カリクレインのヘテロアリール阻害剤 Pending JP2024516073A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163162468P 2021-03-17 2021-03-17
US63/162,468 2021-03-17
PCT/US2022/020482 WO2022197758A1 (en) 2021-03-17 2022-03-16 Heteroaryl inhibitors of plasma kallikrein

Publications (3)

Publication Number Publication Date
JP2024516073A JP2024516073A (ja) 2024-04-12
JP2024516073A5 true JP2024516073A5 (https=) 2025-03-25
JPWO2022197758A5 JPWO2022197758A5 (https=) 2025-03-25

Family

ID=81328275

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023557140A Pending JP2024516073A (ja) 2021-03-17 2022-03-16 血漿カリクレインのヘテロアリール阻害剤

Country Status (10)

Country Link
US (1) US20240228488A1 (https=)
EP (2) EP4585265A3 (https=)
JP (1) JP2024516073A (https=)
KR (1) KR20240004296A (https=)
CN (1) CN117355521A (https=)
AU (1) AU2022240596A1 (https=)
BR (1) BR112023018619A2 (https=)
CA (1) CA3208243A1 (https=)
MX (1) MX2023011014A (https=)
WO (1) WO2022197758A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200143376A (ko) 2018-03-13 2020-12-23 샤이어 휴먼 지네틱 테라피즈 인크. 혈장 칼리크레인 억제제로서의 치환된 이미다조피리딘 및 이의 용도
CN114667289B (zh) 2019-09-18 2025-08-26 武田药品工业有限公司 杂芳基血浆激肽释放酶抑制剂
EP4031547B1 (en) 2019-09-18 2024-07-17 Takeda Pharmaceutical Company Limited Plasma kallikrein inhibitors and uses thereof
BR112023018619A2 (pt) 2021-03-17 2023-11-28 Takeda Pharmaceuticals Co Inibidores de heteroaril de calicreína plasmática
CN117396473A (zh) * 2021-03-17 2024-01-12 武田药品工业株式会社 血浆激肽释放酶的咪唑并吡啶基抑制剂
JP2025531158A (ja) * 2022-09-21 2025-09-19 武田薬品工業株式会社 シクロプロパンカルボン酸の合成
KR20260029377A (ko) * 2023-06-29 2026-03-04 테라닙 인코포레이티드 암 및 염증성 질환 치료에 사용하기 위한 이미다조[1,2-α]피리딘 화합물 및 그 화합물의 제조 방법
CN117069662A (zh) * 2023-10-17 2023-11-17 峰成医药科技(天津)有限公司 一种4,6-二氯-2-(二氟甲基)嘧啶的合成方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4911920A (en) 1986-07-30 1990-03-27 Alcon Laboratories, Inc. Sustained release, comfort formulation for glaucoma therapy
FR2588189B1 (fr) 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
ATE141502T1 (de) 1991-01-15 1996-09-15 Alcon Lab Inc Verwendung von karrageenan in topischen ophthalmologischen zusammensetzungen
US5212162A (en) 1991-03-27 1993-05-18 Alcon Laboratories, Inc. Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions
US6309853B1 (en) 1994-08-17 2001-10-30 The Rockfeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
GB201421088D0 (en) * 2014-11-27 2015-01-14 Kalvista Pharmaceuticals Ltd New enzyme inhibitors
WO2016201052A1 (en) * 2015-06-12 2016-12-15 Global Blood Therapeutics, Inc. Bridged bicyclic kallikrein inhibitors
KR20200143376A (ko) 2018-03-13 2020-12-23 샤이어 휴먼 지네틱 테라피즈 인크. 혈장 칼리크레인 억제제로서의 치환된 이미다조피리딘 및 이의 용도
BR112023018619A2 (pt) 2021-03-17 2023-11-28 Takeda Pharmaceuticals Co Inibidores de heteroaril de calicreína plasmática

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