JP2024509421A5 - - Google Patents

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Publication number
JP2024509421A5
JP2024509421A5 JP2023552539A JP2023552539A JP2024509421A5 JP 2024509421 A5 JP2024509421 A5 JP 2024509421A5 JP 2023552539 A JP2023552539 A JP 2023552539A JP 2023552539 A JP2023552539 A JP 2023552539A JP 2024509421 A5 JP2024509421 A5 JP 2024509421A5
Authority
JP
Japan
Prior art keywords
triazole
hydroxymethyl
pyran
methyl
methoxytetrahydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023552539A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024509421A (ja
JP7771205B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/055224 external-priority patent/WO2022184755A1/en
Publication of JP2024509421A publication Critical patent/JP2024509421A/ja
Publication of JP2024509421A5 publication Critical patent/JP2024509421A5/ja
Application granted granted Critical
Publication of JP7771205B2 publication Critical patent/JP7771205B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023552539A 2021-03-03 2022-03-02 トリアゾリル-メチル置換アルファ-d-ガラクトピラノシド誘導体 Active JP7771205B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EPPCT/EP2021/055348 2021-03-03
EP2021055348 2021-03-03
PCT/EP2022/055224 WO2022184755A1 (en) 2021-03-03 2022-03-02 Triazolyl-methyl substituted alpha-d-galactopyranoside derivatives

Publications (3)

Publication Number Publication Date
JP2024509421A JP2024509421A (ja) 2024-03-01
JP2024509421A5 true JP2024509421A5 (https=) 2025-03-10
JP7771205B2 JP7771205B2 (ja) 2025-11-17

Family

ID=80682779

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023552539A Active JP7771205B2 (ja) 2021-03-03 2022-03-02 トリアゾリル-メチル置換アルファ-d-ガラクトピラノシド誘導体

Country Status (20)

Country Link
US (1) US20240109930A1 (https=)
EP (1) EP4301748B1 (https=)
JP (1) JP7771205B2 (https=)
KR (1) KR20230154221A (https=)
CN (1) CN116888113A (https=)
AU (1) AU2022228660A1 (https=)
BR (1) BR112023017624A2 (https=)
CA (1) CA3209917A1 (https=)
CL (1) CL2023002578A1 (https=)
ES (1) ES3033422T3 (https=)
HR (1) HRP20250833T1 (https=)
HU (1) HUE072194T2 (https=)
IL (1) IL305581A (https=)
MA (1) MA63589B1 (https=)
MX (1) MX2023010241A (https=)
PL (1) PL4301748T3 (https=)
RS (1) RS67032B1 (https=)
TW (1) TWI905393B (https=)
UA (1) UA130562C2 (https=)
WO (1) WO2022184755A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114206893A (zh) 2019-08-09 2022-03-18 爱杜西亚药品有限公司 (杂)芳基-甲基-硫代-β-D-吡喃半乳糖苷衍生物
WO2021028323A1 (en) 2019-08-09 2021-02-18 Idorsia Pharmaceuticals Ltd (2-acetamidyl)thio-beta-d-galactopyranoside derivatives
MA56883B1 (fr) 2019-08-15 2025-04-30 Idorsia Pharmaceuticals Ltd Dérivés de 2-hydroxycycloalcane-1-carbamoyle
CN114585619B (zh) 2019-08-29 2024-09-27 爱杜西亚药品有限公司 α-D-吡喃半乳糖苷衍生物
US12312362B2 (en) 2020-10-06 2025-05-27 Idorsia Pharmaceuticals Ltd Spiro derivatives of Alpha-D-galactopyranosides
EP4237419A1 (en) 2020-11-02 2023-09-06 Idorsia Pharmaceuticals Ltd Galectin-3 inhibiting 2-hydroxycycloalkane-1 -carbamoyl derivatives
CN116806219A (zh) 2021-02-09 2023-09-26 爱杜西亚药品有限公司 羟基杂环烷-氨甲酰基衍生物

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0100172D0 (sv) 2001-01-22 2001-01-22 Ulf Nilsson New inhibitors against galectins
SE0401300D0 (sv) 2004-05-21 2004-05-21 Forskarpatent I Syd Ab Novel Galactoside Inhibitors of Galectins
SE0401301D0 (sv) 2004-05-21 2004-05-21 Forskarpatent I Syd Ab Novel 3-triazolyl-galactoside inhibitors of galectins
DK2906227T3 (en) 2012-10-10 2018-12-10 Galectin Therapeutics Inc GALACTOSE-CONTAINING CARBOHYDRATE COMPOUNDS FOR THE TREATMENT OF DIABETIC Nephropathy
CN104755088A (zh) 2012-10-31 2015-07-01 格莱克特生物技术公司 半乳凝集素-3的半乳糖苷抑制剂及其用于治疗肺纤维化的应用
EP2919802A4 (en) 2012-11-15 2016-09-14 Univ Tufts METHOD, COMPOSITIONS AND KITS FOR TREATING, MODULATING OR PREVENTING ANGIOGENESIS OR FIBROSIS IN A PATIENT USING A GALECTINE PROTEIN HEMMER
CA2970062C (en) 2015-01-30 2023-02-28 Galecto Biotech Ab Alpha-d-galactoside inhibitors of galectins
PL3456717T3 (pl) 2015-07-06 2021-10-25 Gilead Sciences, Inc. Pochodna 4,6-diaminochinolino-3-karbonitrylu jako modulator cot (cancer osaka thyroid) do leczenia choroby zapalnej
EP3621973A4 (en) 2017-05-12 2021-10-27 Galectin Sciences, LLC COMPOUNDS FOR THE PREVENTION AND TREATMENT OF DISEASES AND USES THEREOF
KR20200015528A (ko) 2017-05-12 2020-02-12 갈랙틴 사이언시즈, 엘엘씨 전신 인슐린 내성 질환의 치료용 화합물 및 그의 용도
WO2019067702A1 (en) * 2017-09-27 2019-04-04 Bristol-Myers Squibb Company INHIBITORS WITH SMALL MOLECULES OF GALECTIN-3
US11072626B2 (en) 2017-10-11 2021-07-27 Bristol-Myers Squibb Company Small molecule inhibitors of Galectin-3
CA3080128A1 (en) 2017-10-31 2019-05-09 Galectin Sciences, Llc Selenogalactoside compounds for the treatment of systemic insulin resistance disorders and the use thereof
WO2020104335A1 (en) 2018-11-21 2020-05-28 Galecto Biotech Ab Alpha-d-galactoside inhibitors of galectins
US12269819B2 (en) * 2019-04-10 2025-04-08 Bristol-Myers Squibb Company Small molecule inhibitors of Galectin-3
JP7674276B2 (ja) 2019-07-03 2025-05-09 ガレクト バイオテック エービー ガレクチンの新規なガラクトシド阻害剤
WO2021004940A1 (en) 2019-07-05 2021-01-14 Galecto Biotech Ab Novel galactoside inhibitor of galectins
WO2021028323A1 (en) 2019-08-09 2021-02-18 Idorsia Pharmaceuticals Ltd (2-acetamidyl)thio-beta-d-galactopyranoside derivatives
CN114206893A (zh) 2019-08-09 2022-03-18 爱杜西亚药品有限公司 (杂)芳基-甲基-硫代-β-D-吡喃半乳糖苷衍生物
MA56883B1 (fr) 2019-08-15 2025-04-30 Idorsia Pharmaceuticals Ltd Dérivés de 2-hydroxycycloalcane-1-carbamoyle
CN114585619B (zh) 2019-08-29 2024-09-27 爱杜西亚药品有限公司 α-D-吡喃半乳糖苷衍生物

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