JP2023547241A5 - - Google Patents

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Publication number
JP2023547241A5
JP2023547241A5 JP2023526360A JP2023526360A JP2023547241A5 JP 2023547241 A5 JP2023547241 A5 JP 2023547241A5 JP 2023526360 A JP2023526360 A JP 2023526360A JP 2023526360 A JP2023526360 A JP 2023526360A JP 2023547241 A5 JP2023547241 A5 JP 2023547241A5
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JP
Japan
Application number
JP2023526360A
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Japanese (ja)
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JP7834746B2 (ja
JP2023547241A (ja
JPWO2022090544A5 (https=
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Priority claimed from PCT/EP2021/080276 external-priority patent/WO2022090544A1/en
Publication of JP2023547241A publication Critical patent/JP2023547241A/ja
Publication of JP2023547241A5 publication Critical patent/JP2023547241A5/ja
Publication of JPWO2022090544A5 publication Critical patent/JPWO2022090544A5/ja
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Publication of JP7834746B2 publication Critical patent/JP7834746B2/ja
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JP2023526360A 2020-11-02 2021-11-01 ガレクチン-3を阻害する2-ヒドロキシシクロアルカン-1-カルバモイル誘導体 Active JP7834746B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EPPCT/EP2020/080681 2020-11-02
EP2020080681 2020-11-02
EPPCT/EP2021/053133 2021-02-10
EP2021053133 2021-02-10
PCT/EP2021/080276 WO2022090544A1 (en) 2020-11-02 2021-11-01 Galectin-3 inhibiting 2-hydroxycycloalkane-1 -carbamoyl derivatives

Publications (4)

Publication Number Publication Date
JP2023547241A JP2023547241A (ja) 2023-11-09
JP2023547241A5 true JP2023547241A5 (https=) 2024-11-13
JPWO2022090544A5 JPWO2022090544A5 (https=) 2024-11-13
JP7834746B2 JP7834746B2 (ja) 2026-03-24

Family

ID=78414042

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023526360A Active JP7834746B2 (ja) 2020-11-02 2021-11-01 ガレクチン-3を阻害する2-ヒドロキシシクロアルカン-1-カルバモイル誘導体

Country Status (10)

Country Link
US (1) US12291520B2 (https=)
EP (1) EP4237419A1 (https=)
JP (1) JP7834746B2 (https=)
KR (1) KR20230104190A (https=)
AU (1) AU2021370994A1 (https=)
CA (1) CA3197095A1 (https=)
IL (1) IL302421A (https=)
MX (1) MX2023005039A (https=)
TW (1) TWI910255B (https=)
WO (1) WO2022090544A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114206893A (zh) 2019-08-09 2022-03-18 爱杜西亚药品有限公司 (杂)芳基-甲基-硫代-β-D-吡喃半乳糖苷衍生物
EP4010348B1 (en) 2019-08-09 2023-12-20 Idorsia Pharmaceuticals Ltd (2-acetamidyl)thio-beta-d-galactopyranoside derivatives
JP7604457B2 (ja) 2019-08-15 2024-12-23 イドルシア・ファーマシューティカルズ・リミテッド 2-ヒドロキシシクロアルカン-1-カルバモイル誘導体
CA3148365A1 (en) 2019-08-29 2021-03-04 Martin Bolli Alpha-d-galactopyranoside derivatives
ES3014851T3 (en) 2020-10-06 2025-04-25 Idorsia Pharmaceuticals Ltd Spiro derivatives of alpha-d-galactopyranosides
KR20230145111A (ko) * 2021-02-09 2023-10-17 이도르시아 파마슈티컬스 리미티드 히드록시헤테로시클로알칸-카르바모일 유도체

Family Cites Families (29)

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Publication number Priority date Publication date Assignee Title
SE0100172D0 (sv) 2001-01-22 2001-01-22 Ulf Nilsson New inhibitors against galectins
SE0401301D0 (sv) 2004-05-21 2004-05-21 Forskarpatent I Syd Ab Novel 3-triazolyl-galactoside inhibitors of galectins
SE0401300D0 (sv) 2004-05-21 2004-05-21 Forskarpatent I Syd Ab Novel Galactoside Inhibitors of Galectins
US8828971B2 (en) 2012-10-10 2014-09-09 Galectin Therapeutics, Inc. Galactose-pronged carbohydrate compounds for the treatment of diabetic nephropathy and associated disorders
JP2015535233A (ja) 2012-10-31 2015-12-10 ガレクト・バイオテック・エイビイ ガレクチン−3のガラクトシド阻害剤及び肺線維症のためのその使用
WO2014078655A1 (en) 2012-11-15 2014-05-22 Tufts University Methods, compositions and kits for treating, modulating, or preventing ocular angiogenesis or fibrosis in a subject using a galectin protein inhibitor
JP6904906B2 (ja) 2015-01-30 2021-07-21 ガレクト・バイオテック・エイビイ ガレクチンの新規なガラクトシド阻害剤
KR101974793B1 (ko) 2015-07-06 2019-05-02 길리애드 사이언시즈, 인코포레이티드 Cot 조정제 및 그의 사용 방법
CA3025867A1 (en) 2016-07-12 2018-01-18 Galecto Biotech Ab Alpha-d-galactoside inhibitors of galectins
US20200061095A1 (en) 2017-05-12 2020-02-27 Galectin Sciences, Llc Compounds for the Treatment of Systemic Insulin Resistance Disorders and the Use Thereof
CA3062648A1 (en) 2017-05-12 2018-11-15 Galectin Sciences, Llc Compounds for the prevention and treatment of diseases and the use thereof
WO2019067702A1 (en) 2017-09-27 2019-04-04 Bristol-Myers Squibb Company INHIBITORS WITH SMALL MOLECULES OF GALECTIN-3
WO2019075045A1 (en) 2017-10-11 2019-04-18 Bristol-Myers Squibb Company INHIBITORS WITH SMALL MOLECULES OF GALECTIN-3
AU2018361991A1 (en) 2017-10-31 2020-05-14 Galectin Sciences, Llc Selenogalactoside compounds for the treatment of systemic insulin resistance disorders and the use thereof
JP2022508719A (ja) 2018-10-15 2022-01-19 ガレクト バイオテック エービー ガレクチンのガラクトシド阻害剤のプロドラッグ
CN113366007A (zh) 2018-10-15 2021-09-07 格莱克特生物技术公司 半乳糖凝集素的半乳糖苷抑制剂
JP7486484B2 (ja) * 2018-11-21 2024-05-17 ガレクト バイオテック エービー ガレクチンのα-D-ガラクトシド阻害剤
CN118373810A (zh) * 2018-12-27 2024-07-23 糖模拟物有限公司 抑制c-糖苷的半乳凝素-3
EP3947407B1 (en) * 2019-03-26 2024-06-12 Bristol-Myers Squibb Company Small molecule inhibitors of galectin-3
EP3953349A1 (en) 2019-04-10 2022-02-16 Bristol-Myers Squibb Company Small molecule inhibitors of galectin-3
CA3141436A1 (en) 2019-07-03 2021-01-07 Fredrik Zetterberg Novel galactoside inhibitor of galectins
CN114450282A (zh) 2019-07-05 2022-05-06 格莱克特生物技术公司 半乳糖凝集素的新型半乳糖苷抑制剂
EP4010348B1 (en) 2019-08-09 2023-12-20 Idorsia Pharmaceuticals Ltd (2-acetamidyl)thio-beta-d-galactopyranoside derivatives
CN114206893A (zh) 2019-08-09 2022-03-18 爱杜西亚药品有限公司 (杂)芳基-甲基-硫代-β-D-吡喃半乳糖苷衍生物
JP7604457B2 (ja) 2019-08-15 2024-12-23 イドルシア・ファーマシューティカルズ・リミテッド 2-ヒドロキシシクロアルカン-1-カルバモイル誘導体
CA3148365A1 (en) 2019-08-29 2021-03-04 Martin Bolli Alpha-d-galactopyranoside derivatives
ES3014851T3 (en) 2020-10-06 2025-04-25 Idorsia Pharmaceuticals Ltd Spiro derivatives of alpha-d-galactopyranosides
KR20230145111A (ko) 2021-02-09 2023-10-17 이도르시아 파마슈티컬스 리미티드 히드록시헤테로시클로알칸-카르바모일 유도체
PL4301748T3 (pl) 2021-03-03 2025-09-08 Idorsia Pharmaceuticals Ltd Triazolilo-metylo podstawione pochodne alfa-d-galaktopiranozydu

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