JP2024100972A5 - - Google Patents
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- JP2024100972A5 JP2024100972A5 JP2024084707A JP2024084707A JP2024100972A5 JP 2024100972 A5 JP2024100972 A5 JP 2024100972A5 JP 2024084707 A JP2024084707 A JP 2024084707A JP 2024084707 A JP2024084707 A JP 2024084707A JP 2024100972 A5 JP2024100972 A5 JP 2024100972A5
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- JP
- Japan
- Prior art keywords
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- subject
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- small molecule
- cell
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862656823P | 2018-04-12 | 2018-04-12 | |
| US62/656,823 | 2018-04-12 | ||
| PCT/US2019/026923 WO2019200056A2 (en) | 2018-04-12 | 2019-04-11 | Viral vectors and packaging cell lines |
| JP2021505621A JP7721436B2 (ja) | 2018-04-12 | 2019-04-11 | ウイルスベクター及びパッケージング細胞株 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021505621A Division JP7721436B2 (ja) | 2018-04-12 | 2019-04-11 | ウイルスベクター及びパッケージング細胞株 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024100972A JP2024100972A (ja) | 2024-07-26 |
| JP2024100972A5 true JP2024100972A5 (enExample) | 2025-01-30 |
Family
ID=66287035
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021505621A Active JP7721436B2 (ja) | 2018-04-12 | 2019-04-11 | ウイルスベクター及びパッケージング細胞株 |
| JP2024084707A Pending JP2024100972A (ja) | 2018-04-12 | 2024-05-24 | ウイルスベクター及びパッケージング細胞株 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021505621A Active JP7721436B2 (ja) | 2018-04-12 | 2019-04-11 | ウイルスベクター及びパッケージング細胞株 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US12215337B2 (enExample) |
| EP (1) | EP3775231A2 (enExample) |
| JP (2) | JP7721436B2 (enExample) |
| CN (1) | CN112262214A (enExample) |
| AU (2) | AU2019252285B2 (enExample) |
| BR (1) | BR112020020887A2 (enExample) |
| CA (1) | CA3096458A1 (enExample) |
| IL (1) | IL277936A (enExample) |
| SG (1) | SG11202009975TA (enExample) |
| WO (1) | WO2019200056A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2949648T3 (es) | 2012-12-20 | 2023-10-02 | Purdue Research Foundation | Células T que expresan un receptor antigénico quimérico como terapia contra el cáncer |
| US11325948B2 (en) | 2016-03-19 | 2022-05-10 | Exuma Biotech Corp. | Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL |
| US11111505B2 (en) | 2016-03-19 | 2021-09-07 | Exuma Biotech, Corp. | Methods and compositions for transducing lymphocytes and regulating the activity thereof |
| JP7282521B2 (ja) | 2016-04-08 | 2023-05-29 | パーデュー・リサーチ・ファウンデイション | Ｃａｒ ｔ細胞療法のための方法および組成物 |
| US11850262B2 (en) | 2017-02-28 | 2023-12-26 | Purdue Research Foundation | Compositions and methods for CAR T cell therapy |
| BR112020014913A2 (pt) | 2018-01-22 | 2020-12-08 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Métodos para uso de células t car |
| CA3091674A1 (en) | 2018-02-23 | 2019-08-29 | Endocyte, Inc. | Sequencing method for car t cell therapy |
| CA3096458A1 (en) | 2018-04-12 | 2019-10-17 | Umoja Biopharma, Inc. | Viral vectors and packaging cell lines |
| WO2020106992A1 (en) | 2018-11-21 | 2020-05-28 | Umoja Biopharma, Inc. | Multicistronic vector for surface engineering lentiviral particles |
| WO2021076788A2 (en) * | 2019-10-16 | 2021-04-22 | Umoja Biopharma, Inc. | Retroviral vector for univeral receptor therapy |
| JP2023512071A (ja) * | 2020-01-30 | 2023-03-23 | ウモジャ バイオファーマ， インコーポレイテッド | 二特異性形質導入エンハンサー |
| US20230201440A1 (en) * | 2020-05-08 | 2023-06-29 | Innovative Cellular Therapeutics Holdings, Ltd. | System and method for gene and/or cellular therapy |
| CA3199588A1 (en) * | 2020-11-20 | 2022-05-27 | Andrew Scharenberg | Vector system for delivery of multiple polynucleotides and uses thereof |
| EP4284821A1 (en) | 2021-01-27 | 2023-12-06 | Umoja Biopharma, Inc. | Lentivirus for generating cells expressing anti-cd19 chimeric antigen receptor |
| CN119497751A (zh) * | 2022-05-06 | 2025-02-21 | 乌莫加生物制药公司 | 具有表面刺激分子的病毒颗粒 |
| WO2024098028A2 (en) * | 2022-11-04 | 2024-05-10 | Umoja Biopharma, Inc. | Lentiviral particles displaying fusion molecules and uses thereof |
| WO2024097992A2 (en) * | 2022-11-04 | 2024-05-10 | Umoja Biopharma, Inc. | Particles displaying adhesion-molecule fusions |
| WO2024215987A1 (en) | 2023-04-14 | 2024-10-17 | Sotio Biotech Inc. | IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-15/IL-15Rα CONJUGATES |
| WO2024215989A1 (en) | 2023-04-14 | 2024-10-17 | Sotio Biotech Inc. | ENGINEERED IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-2/IL-15 RECEPTOR βγ AGONISTS |
| WO2024223847A1 (en) | 2023-04-27 | 2024-10-31 | Miltenyi Biotec B.V. & Co. KG | Pseudotyped retroviral vector particle with anti-cd3 display |
| WO2024238153A1 (en) * | 2023-05-15 | 2024-11-21 | Umoja Biopharma, Inc. | Lentiviral delivery of anti-cd20 chimeric antigen receptors |
| WO2024238769A2 (en) * | 2023-05-16 | 2024-11-21 | The Regents Of The University Of California | Inhibitory chimeric antigen receptors that reduce car-t cell "on-target, off-tumor" toxicity |
| WO2025078492A1 (en) | 2023-10-13 | 2025-04-17 | Miltenyi Biotec B.V. & Co. KG | Cd3-targeted nipah-pseudotyped lentiviral vector particles |
| WO2025162379A1 (zh) * | 2024-02-01 | 2025-08-07 | 深圳市济因生物科技有限公司 | 一种多肽及包含所述多肽基因的病毒载体 |
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| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| US5739018A (en) | 1996-08-07 | 1998-04-14 | The Regents Of The University Of California | Packaging cell lines for pseudotyped retroviral vectors |
| US6207455B1 (en) | 1997-05-01 | 2001-03-27 | Lung-Ji Chang | Lentiviral vectors |
| KR100556864B1 (ko) | 1997-05-13 | 2006-03-10 | 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 | 렌티바이러스-기원 유전자 전달 벡터 |
| US6136597A (en) | 1997-09-18 | 2000-10-24 | The Salk Institute For Biological Studies | RNA export element |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| WO2000055378A1 (en) | 1999-03-16 | 2000-09-21 | Dana-Farber Cancer Institute, Inc. | Lentiviral vector system for high quantity screening |
| AU784910B2 (en) | 1999-10-12 | 2006-07-27 | Centre National De La Recherche Scientifique | Lentiviral triplex DNA, and vectors and recombinant cells containing lentiviral triplex DNA |
| US7939059B2 (en) | 2001-12-10 | 2011-05-10 | California Institute Of Technology | Method for the generation of antigen-specific lymphocytes |
| US7135339B2 (en) | 2003-11-20 | 2006-11-14 | University Of Iowa Research Foundation | Methods for producing and using in vivo pseudotyped retroviruses using envelope glycoproteins from lymphocytic choriomeningitis virus (LCMV) |
| JP2008504821A (ja) | 2004-07-01 | 2008-02-21 | バイレクシス コーポレイション | ベクター・パッケージング細胞系列 |
| JP2006085744A (ja) | 2004-09-14 | 2006-03-30 | Matsushita Electric Ind Co Ltd | 磁気記録再生装置及びそのテープスレッディング方法 |
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| EP2016102B1 (en) | 2006-05-03 | 2012-03-21 | Government of the United States of America, Represented by the Secretary, Department of Health and Human Services | Chimeric t cell receptors and related materials and methods of use |
| US8293685B2 (en) | 2007-07-26 | 2012-10-23 | The Regents Of The University Of California | Methods for enhancing bacterial cell display of proteins and peptides |
| US9273283B2 (en) | 2009-10-29 | 2016-03-01 | The Trustees Of Dartmouth College | Method of producing T cell receptor-deficient T cells expressing a chimeric receptor |
| GB0920775D0 (en) | 2009-11-26 | 2010-01-13 | King S College | Cells |
| EP2895203A4 (en) | 2012-06-15 | 2016-09-28 | Imaginab Inc | ANTIGENBINDING CONSTRUCTS FOR CD3 |
| ES2949648T3 (es) | 2012-12-20 | 2023-10-02 | Purdue Research Foundation | Células T que expresan un receptor antigénico quimérico como terapia contra el cáncer |
| CA2956667A1 (en) | 2013-07-29 | 2015-02-05 | Bluebird Bio, Inc. | Multipartite signaling proteins and uses thereof |
| JP6793902B2 (ja) * | 2013-12-20 | 2020-12-02 | ノバルティス アーゲー | 調節可能キメラ抗原受容体 |
| WO2015142661A1 (en) | 2014-03-15 | 2015-09-24 | Novartis Ag | Regulatable chimeric antigen receptor |
| ES2939760T3 (es) | 2014-03-15 | 2023-04-26 | Novartis Ag | Tratamiento de cáncer utilizando un receptor quimérico para antígenos |
| US10301370B2 (en) | 2014-05-02 | 2019-05-28 | The Trustees Of The University Of Pennsylvania | Compositions and methods of chimeric autoantibody receptor T cells |
| GB201412494D0 (en) * | 2014-07-14 | 2014-08-27 | Ospedale San Raffaele And Fond Telethon | Vector production |
| CN113846062B (zh) | 2014-07-25 | 2025-02-21 | 赛拉福柯蒂斯公司 | 用于嵌合抗原受体分子的调控表达的慢病毒载体 |
| TWI805109B (zh) | 2014-08-28 | 2023-06-11 | 美商奇諾治療有限公司 | 對cd19具專一性之抗體及嵌合抗原受體 |
| US20180127781A1 (en) | 2015-01-21 | 2018-05-10 | Fred Hutchinson Cancer Research Center | Cocal envelope pseudotyped retroviral vector producer cells |
| KR102632082B1 (ko) | 2015-02-27 | 2024-02-02 | 아이셀 진 테라퓨틱스 엘엘씨 | 혈액 악성종양을 표적으로 하는 키메라 항원 수용체(car), 조성물 및 이의 용도 |
| GB201503500D0 (en) | 2015-03-02 | 2015-04-15 | Ucl Business Plc | Cell |
| JP6776254B2 (ja) * | 2015-03-16 | 2020-10-28 | イッサム、リサーチ、デベロップメント、カンパニー、オブ、ザ、ヘブライ、ユニバーシティー、オブ、イエルサレム、リミテッドＹｉｓｓｕｍ Ｒｅｓｅａｒｃｈ Ｄｅｖｅｌｏｐｍｅｎｔ Ｃｏｍｐａｎｙ Ｏｆ Ｔｈｅ Ｈｅｂｒｅｗ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｊｅｒｕｓａｌｅｍ Ｌｔｄ． | Ｂ７リガンド二量体界面に由来する単離されたペプチドおよびそれらの使用 |
| AR105433A1 (es) | 2015-07-21 | 2017-10-04 | Novartis Ag | Métodos para mejorar la eficacia y expansión de las células inmunes |
| GB201514875D0 (en) | 2015-08-20 | 2015-10-07 | Autolus Ltd | Receptor |
| CU24649B1 (es) * | 2016-03-19 | 2023-02-13 | Exuma Biotech Corp | Retrovirus recombinantes incompetentes de replicación para la transducción de linfocitos y expansión regulada de los mismos |
| JP7282521B2 (ja) | 2016-04-08 | 2023-05-29 | パーデュー・リサーチ・ファウンデイション | Ｃａｒ ｔ細胞療法のための方法および組成物 |
| WO2017201432A2 (en) * | 2016-05-19 | 2017-11-23 | Jounaidi Youssef | Tethered interleukin-2 to its receptor il-2rbeta, a platform to enhance natural killer and regulatory t cell activity |
| AU2017327663A1 (en) | 2016-09-14 | 2019-04-04 | Université Catholique de Louvain | Modified VSV-G and vaccines thereof |
| AU2017378153B2 (en) | 2016-12-13 | 2024-03-28 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Methods of exogenous drug activation of chemical-induced signaling complexes expressed in engineered cells in vitro and in vivo |
| WO2018132508A1 (en) | 2017-01-10 | 2018-07-19 | The General Hospital Corporation | Methods and compositions relating to ex vivo culture and modulation of t cells |
| CN110612119B (zh) | 2017-02-07 | 2024-10-29 | 西雅图儿童医院（Dba西雅图儿童研究所） | 磷脂醚(ple)car t细胞肿瘤靶向(ctct)剂 |
| CA3053534A1 (en) | 2017-02-17 | 2018-08-23 | Purdue Research Foundation | Targeted ligand-payload based drug delivery for cell therapy |
| US11850262B2 (en) | 2017-02-28 | 2023-12-26 | Purdue Research Foundation | Compositions and methods for CAR T cell therapy |
| CN118895313A (zh) | 2017-09-18 | 2024-11-05 | 埃克苏马生物技术公司 | 用于以基因方式修饰且扩增淋巴细胞以及调节其活性的方法及组合物 |
| EP3720411A4 (en) | 2017-12-07 | 2021-11-24 | Dermavant Sciences GmbH | TOPICAL Ointment FORMULATIONS BY PDE-4 INHIBITORS AND THEIR USE FOR TREATMENT OF SKIN DISEASES |
| BR112020014913A2 (pt) | 2018-01-22 | 2020-12-08 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Métodos para uso de células t car |
| SG11202007426XA (en) | 2018-02-06 | 2020-09-29 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors |
| AU2019218989A1 (en) | 2018-02-12 | 2020-08-27 | The General Hospital Corporation | Chimeric antigen receptors targeting the tumor microenvironment |
| CA3096458A1 (en) | 2018-04-12 | 2019-10-17 | Umoja Biopharma, Inc. | Viral vectors and packaging cell lines |
| KR20210074274A (ko) | 2018-08-06 | 2021-06-21 | 시애틀 칠드런즈 호스피탈 디/비/에이 시애틀 칠드런즈 리서치 인스티튜트 | 합텐 표지된 세포로의 키메라 항원 수용체 t 세포의 자극을 위한 방법 및 조성물 |
| CN112543651B (zh) | 2018-08-07 | 2023-06-02 | 普渡研究基金会 | 使car t细胞恢复活力 |
| WO2020106992A1 (en) | 2018-11-21 | 2020-05-28 | Umoja Biopharma, Inc. | Multicistronic vector for surface engineering lentiviral particles |
| EP3886894B1 (en) | 2018-11-30 | 2024-03-13 | Juno Therapeutics, Inc. | Methods for dosing and treatment of b cell malignancies in adoptive cell therapy |
| WO2021076788A2 (en) | 2019-10-16 | 2021-04-22 | Umoja Biopharma, Inc. | Retroviral vector for univeral receptor therapy |
| US20230220419A1 (en) | 2020-05-27 | 2023-07-13 | The Medical College Of Wisconsin, Inc. | Improved Lentiviral Vector Transfer Plasmid and Methods of Use |
| US11517814B2 (en) | 2020-09-03 | 2022-12-06 | Alan Chalmers | Flavour system |
| CA3199588A1 (en) | 2020-11-20 | 2022-05-27 | Andrew Scharenberg | Vector system for delivery of multiple polynucleotides and uses thereof |
| EP4284821A1 (en) | 2021-01-27 | 2023-12-06 | Umoja Biopharma, Inc. | Lentivirus for generating cells expressing anti-cd19 chimeric antigen receptor |
| CN119497751A (zh) | 2022-05-06 | 2025-02-21 | 乌莫加生物制药公司 | 具有表面刺激分子的病毒颗粒 |
-
2019
- 2019-04-11 CA CA3096458A patent/CA3096458A1/en active Pending
- 2019-04-11 EP EP19719740.3A patent/EP3775231A2/en active Pending
- 2019-04-11 CN CN201980037729.7A patent/CN112262214A/zh active Pending
- 2019-04-11 JP JP2021505621A patent/JP7721436B2/ja active Active
- 2019-04-11 AU AU2019252285A patent/AU2019252285B2/en active Active
- 2019-04-11 WO PCT/US2019/026923 patent/WO2019200056A2/en not_active Ceased
- 2019-04-11 BR BR112020020887-6A patent/BR112020020887A2/pt unknown
- 2019-04-11 SG SG11202009975TA patent/SG11202009975TA/en unknown
- 2019-04-11 US US17/046,701 patent/US12215337B2/en active Active
-
2020
- 2020-10-11 IL IL277936A patent/IL277936A/en unknown
-
2024
- 2024-05-24 JP JP2024084707A patent/JP2024100972A/ja active Pending
- 2024-12-20 US US18/991,176 patent/US20250122533A1/en active Pending
- 2024-12-20 US US18/991,101 patent/US20250122532A1/en active Pending
-
2025
- 2025-09-25 AU AU2025237995A patent/AU2025237995A1/en active Pending
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