JP2024099628A5 - - Google Patents
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- JP2024099628A5 JP2024099628A5 JP2024066182A JP2024066182A JP2024099628A5 JP 2024099628 A5 JP2024099628 A5 JP 2024099628A5 JP 2024066182 A JP2024066182 A JP 2024066182A JP 2024066182 A JP2024066182 A JP 2024066182A JP 2024099628 A5 JP2024099628 A5 JP 2024099628A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical formulation
- concentration
- mannitol
- excipient
- lyophilized
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410002665.6A CN104758922A (zh) | 2014-01-03 | 2014-01-03 | 纽兰格林制剂的配方 |
| CN201410002665.6 | 2014-01-03 | ||
| JP2020082456A JP7100083B2 (ja) | 2014-01-03 | 2020-05-08 | ニューレグリン調合剤の処方 |
| JP2022105452A JP7479068B2 (ja) | 2014-01-03 | 2022-06-30 | ニューレグリン調合剤の処方 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022105452A Division JP7479068B2 (ja) | 2014-01-03 | 2022-06-30 | ニューレグリン調合剤の処方 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024099628A JP2024099628A (ja) | 2024-07-25 |
| JP2024099628A5 true JP2024099628A5 (https=) | 2024-10-08 |
Family
ID=53493186
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016544419A Active JP6703483B2 (ja) | 2014-01-03 | 2014-12-17 | ニューレグリン調合剤の処方 |
| JP2020082456A Active JP7100083B2 (ja) | 2014-01-03 | 2020-05-08 | ニューレグリン調合剤の処方 |
| JP2022105452A Active JP7479068B2 (ja) | 2014-01-03 | 2022-06-30 | ニューレグリン調合剤の処方 |
| JP2024066182A Pending JP2024099628A (ja) | 2014-01-03 | 2024-04-16 | ニューレグリン調合剤の処方 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016544419A Active JP6703483B2 (ja) | 2014-01-03 | 2014-12-17 | ニューレグリン調合剤の処方 |
| JP2020082456A Active JP7100083B2 (ja) | 2014-01-03 | 2020-05-08 | ニューレグリン調合剤の処方 |
| JP2022105452A Active JP7479068B2 (ja) | 2014-01-03 | 2022-06-30 | ニューレグリン調合剤の処方 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US10702585B2 (https=) |
| EP (2) | EP3821904B1 (https=) |
| JP (4) | JP6703483B2 (https=) |
| KR (3) | KR20160105443A (https=) |
| CN (4) | CN104758922A (https=) |
| AU (1) | AU2014375637A1 (https=) |
| BR (1) | BR112016015660A2 (https=) |
| CA (1) | CA2935607A1 (https=) |
| RU (1) | RU2738158C2 (https=) |
| WO (1) | WO2015101182A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5738516B2 (ja) | 2005-12-30 | 2015-06-24 | ゼンサン （シャンハイ） サイエンス アンド テクノロジー リミテッド | 心機能改善のためのニューレグリンの徐放 |
| JP6096262B2 (ja) | 2009-08-25 | 2017-03-15 | ゼンサン （シャンハイ） サイエンス アンド テクノロジー，シーオー．，エルティーディー． | ニューレグリンに基づく心不全の治療方法 |
| CN102139095A (zh) | 2010-01-29 | 2011-08-03 | 上海泽生科技开发有限公司 | 神经调节蛋白用于预防、治疗或延迟心脏缺血再灌注损伤的方法和组合物 |
| WO2013053076A1 (en) | 2011-10-10 | 2013-04-18 | Zensun （Shanghai）Science & Technology Limited | Compositions and methods for treating heart failure |
| NZ702415A (en) | 2012-06-07 | 2016-04-29 | Children’S Hospital Los Angeles | Methods for treating neutropenia using retinoid agonists |
| US10894815B2 (en) | 2012-10-08 | 2021-01-19 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Compositions and methods for treating heart failure in diabetic patients |
| RU2015154737A (ru) | 2013-05-22 | 2017-06-27 | Цзэньсунь (Шанхай) Сайенс Энд Текнолоджи, Ко., Лтд. | Пролонгированное высвобождение нейрегулина для лечения сердечной недостаточности |
| CN104758922A (zh) * | 2014-01-03 | 2015-07-08 | 上海泽生科技开发有限公司 | 纽兰格林制剂的配方 |
| CN105497876B (zh) | 2014-09-24 | 2021-01-15 | 上海泽生科技开发股份有限公司 | 神经调节蛋白用于预防、治疗或延迟心脏室性心律失常的方法和组合物 |
| CN105561298A (zh) | 2014-10-17 | 2016-05-11 | 上海泽生科技开发有限公司 | 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物 |
| PE20210111A1 (es) | 2018-04-11 | 2021-01-19 | Salubris Biotherapeutics Inc | Composiciones de proteina de fusion recombinante neuregulina-1 (nrg-1) humana y metodos para su uso |
| AR121035A1 (es) | 2019-04-01 | 2022-04-13 | Lilly Co Eli | Compuestos de neuregulina-4 y métodos de uso |
| AU2020348436A1 (en) * | 2019-09-16 | 2022-04-07 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Recombinant human neuregulin derivatives and use thereof |
| JP7425459B2 (ja) * | 2019-10-11 | 2024-01-31 | 株式会社シノテスト | 安定化されたｈｍｇｂ１含有溶液 |
| EP4076697A4 (en) * | 2019-12-16 | 2024-01-03 | Seagen Inc. | QUANTIFICATION OF EXCIPIENTS USING HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY |
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| WO1989001489A1 (en) | 1987-08-10 | 1989-02-23 | Commonwealth Scientific And Industrial Research Or | Control of angiogenesis and compositions and methods therefor |
| US7115554B1 (en) | 1993-05-06 | 2006-10-03 | Acorda Therapeutics, Inc. | Methods of increasing myotube formation or survival or muscle cell mitogenesis differentiation or survival using neuregulin GGF III |
| US5716930A (en) | 1991-04-10 | 1998-02-10 | Ludwig Institute For Cancer Research | Glial growth factors |
| US5530109A (en) | 1991-04-10 | 1996-06-25 | Ludwig Institute For Cancer Research | DNA encoding glial mitogenic factors |
| US5834229A (en) | 1991-05-24 | 1998-11-10 | Genentech, Inc. | Nucleic acids vectors and host cells encoding and expressing heregulin 2-α |
| US6750196B1 (en) | 1995-03-27 | 2004-06-15 | Acorda Therapeutics | Methods of treating disorders of the eye |
| US5912326A (en) | 1995-09-08 | 1999-06-15 | President And Fellows Of Harvard College | Cerebellum-derived growth factors |
| WO1998035036A1 (en) | 1997-02-10 | 1998-08-13 | Genentech, Inc. | Heregulin variants |
| JP2001519400A (ja) | 1997-10-14 | 2001-10-23 | ケンブリッジ ニューロサイエンス インク． | ニューレグリン使用を含む治療法 |
| US6054261A (en) | 1998-05-20 | 2000-04-25 | Q-Pharma, Inc. | Coenzyme Q10 compositions for organ protection during perfusion |
| AUPP785098A0 (en) | 1998-12-21 | 1999-01-21 | Victor Chang Cardiac Research Institute, The | Treatment of heart disease |
| US6635249B1 (en) | 1999-04-23 | 2003-10-21 | Cenes Pharmaceuticals, Inc. | Methods for treating congestive heart failure |
| CN1138785C (zh) | 1999-06-04 | 2004-02-18 | 周明东 | 生长因子神经调节蛋白及其类似物的新应用 |
| AUPQ105799A0 (en) | 1999-06-18 | 1999-07-08 | Victor Chang Cardiac Research Institute, The | Cell growth inhibition |
| KR20030016233A (ko) | 2000-02-28 | 2003-02-26 | 디코드 제네틱스 이에이치에프 | 사람 정신분열증 유전자 |
| IL153052A0 (en) * | 2000-05-23 | 2003-06-24 | Cenes Pharmaceuticals Inc | Nrg-2 nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods |
| US7375185B2 (en) | 2000-09-12 | 2008-05-20 | The United States Of America As Represented By The Department Of Health And Human Services | Cardiac myosin light chain kinase polypeptide, encoding nucleic acid, and methods of use |
| US6482624B2 (en) | 2000-11-14 | 2002-11-19 | Pe Corporation (Ny) | Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof |
| RU2180843C1 (ru) | 2001-02-19 | 2002-03-27 | Новокузнецкий государственный институт усовершенствования врачей | Способ профилактики повторного инфаркта миокарда |
| DE10124387A1 (de) * | 2001-05-18 | 2002-11-28 | Basf Ag | Hydrophob modifizierte Polyethylenimine und Polyvinylamine zur Antiknitterausrüstung von cellulosehaltigen Textilien |
| WO2003099320A1 (en) | 2002-05-24 | 2003-12-04 | Zensun (Shanghai) Sci-Tech.Ltd | Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy |
| CN1498656A (zh) | 2002-11-08 | 2004-05-26 | 上海泽生科技开发有限公司 | 神经调节蛋白用于心肌梗死治疗的方法和组合物 |
| CA2506630A1 (en) | 2002-11-27 | 2004-06-17 | Artesian Therapeutics, Inc. | Heart failure gene determination and therapeutic screening |
| EP1631268A2 (en) | 2003-05-21 | 2006-03-08 | Board Of Regents The University Of Texas System | Inhibition of protein kinase c-mu (pkd) as a treatment for cardiac hypertrophy and heart failure |
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| US20080213395A1 (en) | 2004-10-14 | 2008-09-04 | Adventures Plus Pty Ltd | Method for the Treatment of Gastrointestinal and Other Disorders with an Admixture of Vitamins |
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| WO2006081190A2 (en) * | 2005-01-25 | 2006-08-03 | Five Prime Therapeutics, Inc. | Compositions and methods for treating cardiac conditions |
| US20070141548A1 (en) | 2005-03-11 | 2007-06-21 | Jorg Kohl | Organ transplant solutions and method for transplanting organs |
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| CN1768859A (zh) | 2005-10-24 | 2006-05-10 | 天津大学 | 基于醛基的微粒表面多重生物功能因子组装方法 |
| US20070213264A1 (en) | 2005-12-02 | 2007-09-13 | Mingdong Zhou | Neuregulin variants and methods of screening and using thereof |
| JP5738516B2 (ja) | 2005-12-30 | 2015-06-24 | ゼンサン （シャンハイ） サイエンス アンド テクノロジー リミテッド | 心機能改善のためのニューレグリンの徐放 |
| CN101394861A (zh) * | 2005-12-30 | 2009-03-25 | 上海泽生科技开发有限公司 | 纽兰格林持续给药能改善心脏功能 |
| ATE502998T1 (de) | 2006-07-07 | 2011-04-15 | Procter & Gamble | Waschmittelzusammensetzungen |
| US9580515B2 (en) | 2006-08-21 | 2017-02-28 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Neukinase, a downstream protein of neuregulin |
| JP2010517023A (ja) | 2007-01-25 | 2010-05-20 | エフ．ホフマン−ラ ロシュ アーゲー | 心不全の評価におけるｉｇｆｂｐ−７の使用 |
| CN101310779A (zh) | 2007-05-25 | 2008-11-26 | 上海泽生科技开发有限公司 | 包含神经调节蛋白的装置及药物制剂 |
| CN101310766B (zh) | 2007-05-25 | 2014-04-16 | 上海泽生科技开发有限公司 | 神经调节蛋白的新用途 |
| US20090156488A1 (en) * | 2007-09-12 | 2009-06-18 | Zensun (Shanghai) Science & Technology Limited | Use of neuregulin for organ preservation |
| US20110212108A1 (en) | 2008-05-09 | 2011-09-01 | The Regents Of The University Of California | Neuregulin/erbb signaling and integrin |
| CN102159236A (zh) | 2008-07-17 | 2011-08-17 | 阿索尔达治疗公司 | 用于治疗或预防心力衰竭的神经调节蛋白或其亚序列的治疗性施剂 |
| JP5743898B2 (ja) | 2008-11-28 | 2015-07-01 | ゼンサン （シャンハイ） サイエンス アンド テクノロジー リミテッド | ニューレグリンペプチド及びその使用 |
| JP2012509908A (ja) | 2008-11-28 | 2012-04-26 | ゼンサン （シャンハイ） サイエンス アンド テクノロジー リミテッド | ニューレグリン及び心臓幹細胞 |
| CN102470161A (zh) | 2009-06-09 | 2012-05-23 | 上海泽生科技开发有限公司 | 神经调节蛋白用于治疗心力衰竭的有效剂量 |
| EP3087998B1 (en) | 2009-06-09 | 2019-09-04 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Neuregulin based methods for treating heart failure |
| JP6096262B2 (ja) | 2009-08-25 | 2017-03-15 | ゼンサン （シャンハイ） サイエンス アンド テクノロジー，シーオー．，エルティーディー． | ニューレグリンに基づく心不全の治療方法 |
| CN102139095A (zh) | 2010-01-29 | 2011-08-03 | 上海泽生科技开发有限公司 | 神经调节蛋白用于预防、治疗或延迟心脏缺血再灌注损伤的方法和组合物 |
| PL2544537T3 (pl) * | 2010-03-10 | 2017-10-31 | Cempra Pharmaceuticals Inc | Pozajelitowe preparaty antybiotyków makrolidowych |
| US9029328B2 (en) | 2010-03-24 | 2015-05-12 | The Brigham And Women's Hospital, Inc. | Methods for cardioprotection and cardioregeneration with dimers of EGF family ligands |
| CN104997803B (zh) | 2010-07-22 | 2019-07-09 | 雷文制药有限公司 | 包含使用磁偶极子稳定化溶液的治疗或改善疾病并增强表现的方法和组合物 |
| CN102230084B (zh) * | 2011-06-14 | 2013-01-23 | 东北大学 | 低品位含砷难浸金矿的包覆生物氧化预处理方法 |
| WO2013053076A1 (en) | 2011-10-10 | 2013-04-18 | Zensun （Shanghai）Science & Technology Limited | Compositions and methods for treating heart failure |
| AU2013243948A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins associated with human disease |
| US10894815B2 (en) | 2012-10-08 | 2021-01-19 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Compositions and methods for treating heart failure in diabetic patients |
| EP2964249A1 (en) | 2013-03-06 | 2016-01-13 | Acorda Therapeutics, Inc. | Therapeutic dosing of a neuregulin or a fragment thereof for treatment or prophylaxis of heart failure |
| RU2015154737A (ru) | 2013-05-22 | 2017-06-27 | Цзэньсунь (Шанхай) Сайенс Энд Текнолоджи, Ко., Лтд. | Пролонгированное высвобождение нейрегулина для лечения сердечной недостаточности |
| CN110840895A (zh) | 2013-07-23 | 2020-02-28 | 上海泽生科技开发股份有限公司 | 使用维生素b组合物促进胃肠系统动力的方法 |
| CN104758300A (zh) | 2014-01-02 | 2015-07-08 | 上海泽生科技开发有限公司 | 维生素d及其组合物的抗菌用途 |
| CN104758922A (zh) | 2014-01-03 | 2015-07-08 | 上海泽生科技开发有限公司 | 纽兰格林制剂的配方 |
| CN105497876B (zh) | 2014-09-24 | 2021-01-15 | 上海泽生科技开发股份有限公司 | 神经调节蛋白用于预防、治疗或延迟心脏室性心律失常的方法和组合物 |
| CN105561298A (zh) | 2014-10-17 | 2016-05-11 | 上海泽生科技开发有限公司 | 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物 |
-
2014
- 2014-01-03 CN CN201410002665.6A patent/CN104758922A/zh active Pending
- 2014-01-03 CN CN201911388095.8A patent/CN110946993A/zh active Pending
- 2014-12-17 RU RU2016131667A patent/RU2738158C2/ru active
- 2014-12-17 EP EP20195273.6A patent/EP3821904B1/en active Active
- 2014-12-17 CA CA2935607A patent/CA2935607A1/en not_active Abandoned
- 2014-12-17 WO PCT/CN2014/094073 patent/WO2015101182A1/zh not_active Ceased
- 2014-12-17 KR KR1020167020428A patent/KR20160105443A/ko not_active Ceased
- 2014-12-17 KR KR1020237012378A patent/KR20230054749A/ko not_active Ceased
- 2014-12-17 EP EP14876973.0A patent/EP3090756B2/en active Active
- 2014-12-17 KR KR1020227021093A patent/KR102522140B1/ko active Active
- 2014-12-17 CN CN201911390381.8A patent/CN111012898A/zh active Pending
- 2014-12-17 US US15/109,583 patent/US10702585B2/en active Active
- 2014-12-17 BR BR112016015660A patent/BR112016015660A2/pt not_active IP Right Cessation
- 2014-12-17 JP JP2016544419A patent/JP6703483B2/ja active Active
- 2014-12-17 AU AU2014375637A patent/AU2014375637A1/en not_active Abandoned
- 2014-12-17 CN CN201480071227.3A patent/CN105960248A/zh active Pending
-
2020
- 2020-05-08 JP JP2020082456A patent/JP7100083B2/ja active Active
- 2020-06-05 US US16/894,540 patent/US11969458B2/en active Active
-
2022
- 2022-06-30 JP JP2022105452A patent/JP7479068B2/ja active Active
-
2024
- 2024-03-27 US US18/618,991 patent/US20250073306A1/en active Pending
- 2024-04-16 JP JP2024066182A patent/JP2024099628A/ja active Pending
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