JP2024037864A5 - - Google Patents

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JP2024037864A5
JP2024037864A5 JP2023209915A JP2023209915A JP2024037864A5 JP 2024037864 A5 JP2024037864 A5 JP 2024037864A5 JP 2023209915 A JP2023209915 A JP 2023209915A JP 2023209915 A JP2023209915 A JP 2023209915A JP 2024037864 A5 JP2024037864 A5 JP 2024037864A5
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cells
human
rpe
rpe cells
preparation
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JP2024037864A (ja
JP7716463B2 (ja
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JP2023209915A 2011-11-14 2023-12-13 ヒトrpe細胞医薬品およびその使用 Active JP7716463B2 (ja)

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JP2025120956A JP2025161815A (ja) 2011-11-14 2025-07-18 ヒトrpe細胞医薬品およびその使用

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US201161559521P 2011-11-14 2011-11-14
US61/559,521 2011-11-14
US201261589741P 2012-01-23 2012-01-23
US61/589,741 2012-01-23
US201261724047P 2012-11-08 2012-11-08
US61/724,047 2012-11-08
JP2019098508A JP6899865B2 (ja) 2011-11-14 2019-05-27 ヒトrpe細胞医薬品およびその使用
JP2021049493A JP7081016B2 (ja) 2011-11-14 2021-03-24 ヒトrpe細胞医薬品およびその使用
JP2022084915A JP7404441B2 (ja) 2011-11-14 2022-05-25 ヒトrpe細胞医薬品およびその使用

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JP2024037864A JP2024037864A (ja) 2024-03-19
JP2024037864A5 true JP2024037864A5 (https=) 2024-08-22
JP7716463B2 JP7716463B2 (ja) 2025-07-31

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JP2014541421A Active JP6506023B2 (ja) 2011-11-14 2012-11-14 ヒトrpe細胞医薬品およびその使用
JP2017183914A Active JP6563996B2 (ja) 2011-11-14 2017-09-25 ヒトrpe細胞医薬品およびその使用
JP2019098508A Active JP6899865B2 (ja) 2011-11-14 2019-05-27 ヒトrpe細胞医薬品およびその使用
JP2021049493A Active JP7081016B2 (ja) 2011-11-14 2021-03-24 ヒトrpe細胞医薬品およびその使用
JP2022084915A Active JP7404441B2 (ja) 2011-11-14 2022-05-25 ヒトrpe細胞医薬品およびその使用
JP2023209915A Active JP7716463B2 (ja) 2011-11-14 2023-12-13 ヒトrpe細胞医薬品およびその使用
JP2025120956A Pending JP2025161815A (ja) 2011-11-14 2025-07-18 ヒトrpe細胞医薬品およびその使用

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JP2014541421A Active JP6506023B2 (ja) 2011-11-14 2012-11-14 ヒトrpe細胞医薬品およびその使用
JP2017183914A Active JP6563996B2 (ja) 2011-11-14 2017-09-25 ヒトrpe細胞医薬品およびその使用
JP2019098508A Active JP6899865B2 (ja) 2011-11-14 2019-05-27 ヒトrpe細胞医薬品およびその使用
JP2021049493A Active JP7081016B2 (ja) 2011-11-14 2021-03-24 ヒトrpe細胞医薬品およびその使用
JP2022084915A Active JP7404441B2 (ja) 2011-11-14 2022-05-25 ヒトrpe細胞医薬品およびその使用

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US (4) US20130195806A1 (https=)
EP (2) EP3563860A1 (https=)
JP (7) JP6506023B2 (https=)
KR (1) KR102054904B1 (https=)
CN (2) CN104080464A (https=)
AU (5) AU2012340020A1 (https=)
CA (2) CA2855941A1 (https=)
CY (1) CY1121819T1 (https=)
DK (1) DK2780022T4 (https=)
ES (1) ES2734453T3 (https=)
FI (1) FI2780022T4 (https=)
GB (1) GB2496969A (https=)
HK (1) HK1202456A1 (https=)
HR (1) HRP20191110T1 (https=)
HU (1) HUE044778T2 (https=)
IL (5) IL320536A (https=)
LT (1) LT2780022T (https=)
PL (1) PL2780022T3 (https=)
PT (1) PT2780022T (https=)
RS (1) RS59050B1 (https=)
SI (1) SI2780022T1 (https=)
TW (5) TWI719277B (https=)
WO (1) WO2013074681A1 (https=)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0507074A (pt) 2004-01-23 2007-06-19 Advanced Cell Tech Inc modalidades aperfeiçoadas para o tratamento de doenças degenerativas da retina
US7794704B2 (en) 2004-01-23 2010-09-14 Advanced Cell Technology, Inc. Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration
IL292561A (en) 2007-10-12 2022-06-01 Astellas Inst For Regenerative Medicine Improved methods of rpe cell production and rpe cell preparations
US10485829B2 (en) 2009-11-17 2019-11-26 Astellas Institute For Regenerative Medicine Methods of producing human RPE cells and pharmaceutical preparations of human RPE cells
US10852069B2 (en) 2010-05-04 2020-12-01 Fractal Heatsink Technologies, LLC System and method for maintaining efficiency of a fractal heat sink
EP2596119B8 (en) 2010-07-23 2021-06-02 Astellas Institute for Regenerative Medicine Methods for detection of rare subpopulations of cells and highly purified compositions of cells
US11021733B2 (en) 2011-09-26 2021-06-01 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
JP6329072B2 (ja) 2011-09-26 2018-05-23 キアゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング 細胞外核酸の安定化および単離
CN103827303B (zh) 2011-09-26 2021-10-22 普瑞阿那利提克斯有限公司 细胞外核酸的稳定化和分离
TWI719277B (zh) * 2011-11-14 2021-02-21 美商安斯泰來再生醫藥協會 人類rpe細胞之醫藥組合物及其用途
CN104755628B (zh) 2012-09-25 2019-03-01 凯杰有限公司 生物样品的稳定化
EP2951290B1 (en) 2013-02-01 2017-11-29 The United States of America, as represented by The Secretary, Department of Health and Human Services Method for generating retinal pigment epithelium (rpe) cells from induced pluripotent stem cells (ipscs)
JP6407248B2 (ja) 2013-03-18 2018-10-17 キアゲン ゲーエムベーハー 細胞外核酸の安定化および単離
US11525155B2 (en) 2013-03-18 2022-12-13 Qiagen Gmbh Stabilisation of biological samples
BR112016011096A2 (pt) 2013-11-27 2017-09-19 Kyoto Prefectural Public Univ Corp Aplicação de laminina à cultura de célula endotelial da córnea
CA2933083A1 (en) 2013-12-11 2015-06-18 Pfizer Limited Method for producing retinal pigment epithelial cells
CN106102766A (zh) * 2014-01-22 2016-11-09 皮埃尔与玛丽·居里大学 - 巴黎第六大学 用于治疗视网膜炎症的试剂
EP2898896A1 (en) * 2014-01-22 2015-07-29 Université Pierre et Marie Curie (Paris 6) Agents for use in the treatment of retinal inflammation
JP6664332B2 (ja) * 2014-03-18 2020-03-13 キアゲン ゲーエムベーハー 細胞外核酸の安定化および単離
WO2015175504A1 (en) * 2014-05-12 2015-11-19 The Johns Hopkins University Differentiation of human pluripotent stem cells into retinal pigment epithelium using hif1 inhibitors
US10457915B2 (en) 2014-05-15 2019-10-29 International Stem Cell Corporation Chemical differentiation of pluripotentstem cells into retinal epithelial cells
AU2015261380B2 (en) 2014-05-16 2021-04-15 Koninklijke Nederlandse Akademie Van Wetenschappen Improved culture method for organoids
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
US20160095307A1 (en) 2014-10-07 2016-04-07 NuTech Medical, Inc. Method and composition for hypothermic storage of placental tissue
KR20210013299A (ko) 2014-10-17 2021-02-03 코디악 사이언시스 인코포레이티드 부티릴콜린에스테라제 양성이온성 중합체 컨쥬게이트
CN121891508A (zh) * 2014-10-31 2026-04-21 京都府公立大学法人 使用层粘连蛋白的新的角膜的治疗
EP3213761B1 (en) * 2014-10-31 2021-05-19 Kyoto Prefectural Public University Corporation Novel treatment of retina using laminin
WO2016097183A1 (en) * 2014-12-18 2016-06-23 Universite Pierre Et Marie Curie (Paris 6) Transgenic rpe cells overexpressing otx2 for the treatment of retinal degeneration
WO2016108240A1 (en) 2014-12-30 2016-07-07 Cell Cure Neurosciences Ltd. Assessing retinal pigment epithelial cell populations
CN114533761A (zh) * 2014-12-30 2022-05-27 细胞治疗神经科学有限公司 治疗视网膜疾病的方法
KR20170115514A (ko) 2014-12-30 2017-10-17 셀 큐어 뉴로사이언시스 리미티드 Rpe 세포 집단 및 이를 생성하는 방법
ES2980659T3 (es) * 2015-03-23 2024-10-02 Astellas Inst For Regenerative Medicine Ensayos mejorados de potencia de células de epitelio pigmentario retiniano (EPR) humano y progenitores de fotorreceptores
CN105013010B (zh) * 2015-07-07 2018-01-12 中山大学中山眼科中心 一种辅助iPS‑RPE移植的层粘连蛋白膜
WO2017021973A1 (en) 2015-08-05 2017-02-09 Cell Cure Neurosciences Ltd. Preparation of retinal pigment epithelium cells
SG10201913250SA (en) 2015-08-18 2020-03-30 Astellas Inst For Regenerative Medicine Clinical formulations
KR20260003355A (ko) * 2015-09-08 2026-01-06 후지필름 셀룰러 다이내믹스, 인코포레이티드 줄기 세포에서 유래된 망막색소상피의 macs 기반 정제
EP3377645B1 (en) 2015-11-20 2023-10-04 Qiagen GmbH Method of preparing sterilized compositions for stabilization of extracellular nucleic acids
KR102799807B1 (ko) 2015-12-30 2025-04-24 코디악 사이언시스 인코포레이티드 항체 및 이의 접합체
GB201603569D0 (en) 2016-03-01 2016-04-13 Koninklijke Nederlandse Akademie Van Wetenschappen Improved differentiation method
CN106420809B (zh) * 2016-08-31 2017-08-08 浙江济民制药股份有限公司 一种眼科手术灌注液
WO2018111981A1 (en) * 2016-12-13 2018-06-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of preparing an isolated or purified population of thymic emigrant cells and methods of treatment using same
WO2018119142A1 (en) 2016-12-21 2018-06-28 Amgen Inc. Anti-tnf alpha antibody formulations
US11076984B2 (en) * 2017-03-13 2021-08-03 Gyroscope Therapeutics Limited Method of performing subretinal drainage and agent delivery
EP3595687A1 (en) * 2017-03-16 2020-01-22 Lineage Cell Therapeutics, Inc. Methods for measuring therapeutic effects of retinal disease therapies
CA3061900A1 (en) * 2017-05-01 2018-11-08 The Board Of Supervisors Of Louisiana State University And Agriculturaand Mechanical College Compositions and methods for treating ocular pathologies
GB201721615D0 (en) 2017-12-21 2018-02-07 Koninklijke Nederlandse Akademie Van Wetenschappen Immune cell organoid co-cultures
BR112020013238A2 (pt) * 2017-12-29 2020-12-01 Cell Cure Neurosciences Ltd. composição e método para formular células do epitélio pigmentar da retina bem como uso da dita composição para tratar uma condição retiniana
US12029683B2 (en) 2018-02-22 2024-07-09 Alcon Inc. Ocular implant and delivery system
MX2020009152A (es) * 2018-03-02 2020-11-09 Kodiak Sciences Inc Anticuerpos de il-6 y constructos de fusion y conjugados de los mismos.
AU2019385332B2 (en) * 2018-11-19 2025-09-11 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Biodegradable tissue replacement implant and its use
GB201819224D0 (en) 2018-11-26 2019-01-09 Koninklijke Nederlandse Akademie Van Wetenschappen Hepatocyte expansion methods
US12454701B2 (en) * 2018-12-05 2025-10-28 Abeona Therapeutics Inc. Recombinant adeno-associated viral vector for gene delivery
JP7701879B2 (ja) * 2019-05-28 2025-07-02 エフ. ホフマン-ラ ロシュ アーゲー 単球前駆細胞を生成するための方法
CN118718181A (zh) 2019-06-05 2024-10-01 里珍纳龙药品有限公司 用于精确剂量递送的装置及方法
KR102198942B1 (ko) * 2019-07-02 2021-01-05 의료법인 성광의료재단 Pedf를 발현하거나 모세포에 비하여 pedf를 과발현하도록 유전적으로 조작된 중간엽 줄기세포
EP4013297A4 (en) 2019-08-16 2023-12-13 Poltorak Technologies, LLC DEVICE AND METHOD FOR MEDICAL DIAGNOSTICS
CA3157509A1 (en) 2019-10-10 2021-04-15 Kodiak Sciences Inc. Methods of treating an eye disorder
WO2021086911A1 (en) 2019-10-30 2021-05-06 Astellas Institute For Regenerative Medicine Methods for producing retinal pigment epithelium cells
US12570955B2 (en) 2019-11-22 2026-03-10 Sigilon Therapeutics, Inc. Monoclonal cell lines expressing an exogenous substance and uses thereof
CA3167649A1 (en) 2020-01-21 2021-07-29 Takeda Pharmaceutical Company Limited Compositions and methods of cryopreserving cells
JP2023513208A (ja) * 2020-02-07 2023-03-30 ザ トラスティーズ オブ コロンビア ユニバーシティー イン ザ シティー オブ ニューヨーク 神経変性の発症を遅延させるかまたは神経変性を処置するためのメタボロームのリプログラミング
TW202216158A (zh) * 2020-07-10 2022-05-01 國立研究開發法人理化學研究所 網膜色素上皮細胞之移植用存活促進劑
CN112544612A (zh) * 2020-12-18 2021-03-26 江苏艾尔康生物医药科技有限公司 冻存液及其在rpe细胞冻存中的应用
CN112834411B (zh) * 2021-01-07 2022-05-27 上海交通大学 应用于质谱流式技术的金属纳米探针及制备方法和应用
US20250000788A1 (en) * 2021-01-26 2025-01-02 Sigilon Therapeutics, Inc. Biocompatible devices for cell-based therapies and related methods
CN112926116B (zh) * 2021-03-01 2023-02-17 哈尔滨工业大学 一种基于虚拟现实的体育馆火灾疏散行为数据收集系统及其收集方法
CN114246938A (zh) * 2022-01-25 2022-03-29 中山大学中山眼科中心 Il-4在制备用于治疗视网膜变性疾病药物中的应用
WO2023149420A1 (ja) * 2022-02-01 2023-08-10 株式会社坪田ラボ 近視を予防または治療するための方法および組成物
CN114561356B (zh) * 2022-03-09 2022-09-13 北京呈诺医学科技有限公司 影响细胞因子分泌的方法及应用
CA3254454A1 (en) * 2022-03-16 2025-03-04 Racthera Co., Ltd. METHOD OF TRANSPLANTATION
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device
WO2024218311A1 (fr) * 2023-04-21 2024-10-24 Pulsesight Therapeutics Compositions à base de décorine pour la réparation et la régéneration de l'épithélium pigmentaire de la rétine
AU2024268057A1 (en) * 2023-05-05 2025-12-04 The Regents Of The University Of California Retinal pigment epithelium cell therapy
CN117625536B (zh) * 2024-01-26 2024-04-30 中国人民解放军总医院第三医学中心 一种人视网膜色素上皮细胞的纯化、培养方法

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4138205A (en) 1975-12-15 1979-02-06 Hydro Pulse Corporation Movable stator walls permitting access to tubing in peristaltic pump
US5610753A (en) 1991-12-12 1997-03-11 Eastman Kodak Company Optical design of laser scanner to reduce thermal sensitivity
GB9608145D0 (en) * 1996-04-19 1996-06-26 British Tech Group Wound healing
US20040086494A1 (en) * 1996-10-07 2004-05-06 John Constance Mary Immune privileged cells for delivery of proteins and peptides
US5998423A (en) 1996-10-08 1999-12-07 Therasys, Inc. Methods for modulating melanin production
US6440933B1 (en) 1997-09-10 2002-08-27 University Of Florida Compounds and method for the prevention and treatment of diabetic retinopathy
JP2002500202A (ja) * 1998-01-02 2002-01-08 タイタン ファーマシューティカルズ, インコーポレイテッド 免疫優位部位の生成のための色素性網膜上皮細胞の使用
US7410798B2 (en) 2001-01-10 2008-08-12 Geron Corporation Culture system for rapid expansion of human embryonic stem cells
US6943153B1 (en) 1999-03-15 2005-09-13 The Regents Of The University Of California Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
US6331313B1 (en) 1999-10-22 2001-12-18 Oculex Pharmaceticals, Inc. Controlled-release biocompatible ocular drug delivery implant devices and methods
US6576422B1 (en) * 2000-10-17 2003-06-10 Rohm And Haas Company Method for identifying products employing gene expression
AU2002236495B2 (en) 2000-11-29 2006-05-11 Allergan, Inc. Intraocular implants for preventing transplant rejection in the eye
WO2002087530A1 (en) * 2001-04-27 2002-11-07 The General Hospital Corporation Tyrosinase assay
JP2004538005A (ja) * 2001-08-08 2004-12-24 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア シアル酸に結合するタンパク質を有するウイルスベクターの精製法
US20030232430A1 (en) 2001-11-26 2003-12-18 Advanced Cell Technology Methods for making and using reprogrammed human somatic cell nuclei and autologous and isogenic human stem cells
AU2003235652A1 (en) 2002-01-15 2003-07-30 Advanced Cell Technology, Inc. Cloning b and t lymphocytes
US20040091936A1 (en) 2002-05-24 2004-05-13 Michael West Bank of stem cells for producing cells for transplantation having HLA antigens matching those of transplant recipients, and methods for making and using such a stem cell bank
US7803750B2 (en) 2002-07-29 2010-09-28 Duke University Method of modulating melanin production
BRPI0507074A (pt) * 2004-01-23 2007-06-19 Advanced Cell Tech Inc modalidades aperfeiçoadas para o tratamento de doenças degenerativas da retina
US7794704B2 (en) * 2004-01-23 2010-09-14 Advanced Cell Technology, Inc. Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration
US7309487B2 (en) * 2004-02-09 2007-12-18 George Inana Methods and compositions for detecting and treating retinal diseases
US7893315B2 (en) 2004-11-04 2011-02-22 Advanced Cell Technology, Inc. Derivation of embryonic stem cells and embryo-derived cells
CA3015835A1 (en) 2004-11-04 2006-05-18 Astellas Institute For Regenerative Medicine Derivation of embryonic stem cells
ZA200901914B (en) * 2006-09-22 2010-06-30 Riken Stem cell culture medium and method
IL292561A (en) * 2007-10-12 2022-06-01 Astellas Inst For Regenerative Medicine Improved methods of rpe cell production and rpe cell preparations
GB0806746D0 (en) 2008-04-14 2008-05-14 Ucl Business Plc Membrane
WO2009129497A2 (en) * 2008-04-18 2009-10-22 Arizona Board Of Regents, A Body Corp. Of The State Of Arizona, Acting For And On Behalf Of The University Of Arizona Methods and compositions for treating and identifying compounds to treat age-related macular degeneration
US10485829B2 (en) * 2009-11-17 2019-11-26 Astellas Institute For Regenerative Medicine Methods of producing human RPE cells and pharmaceutical preparations of human RPE cells
EP2596119B8 (en) * 2010-07-23 2021-06-02 Astellas Institute for Regenerative Medicine Methods for detection of rare subpopulations of cells and highly purified compositions of cells
US20110052678A1 (en) * 2010-11-05 2011-03-03 Shantha Totada R Method for treating age related macular degeneration
JP6185907B2 (ja) 2011-03-30 2017-08-23 セルラー ダイナミクス インターナショナル, インコーポレイテッド 神経分化のための多能性幹細胞の予備刺激
WO2012149484A2 (en) * 2011-04-29 2012-11-01 University Of Southern California Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate
TWI719277B (zh) * 2011-11-14 2021-02-21 美商安斯泰來再生醫藥協會 人類rpe細胞之醫藥組合物及其用途
WO2016037159A1 (en) * 2014-09-05 2016-03-10 Ocata Therapeutics, Inc. Retinal ganglion cells and progenitors thereof

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