JP2023554405A5 - - Google Patents
Info
- Publication number
- JP2023554405A5 JP2023554405A5 JP2023536454A JP2023536454A JP2023554405A5 JP 2023554405 A5 JP2023554405 A5 JP 2023554405A5 JP 2023536454 A JP2023536454 A JP 2023536454A JP 2023536454 A JP2023536454 A JP 2023536454A JP 2023554405 A5 JP2023554405 A5 JP 2023554405A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- alkoxy
- group
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025005438A JP7744538B2 (ja) | 2020-12-17 | 2025-01-15 | Ｎ－（２－（４－シアノチアゾリジン－３－イル）－２－オキソエチル）－キノリン－４－カルボキサミド |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063126593P | 2020-12-17 | 2020-12-17 | |
| US63/126,593 | 2020-12-17 | ||
| PCT/IB2021/061839 WO2022130270A1 (en) | 2020-12-17 | 2021-12-16 | N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)- quinoline-4-carboxamides |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025005438A Division JP7744538B2 (ja) | 2020-12-17 | 2025-01-15 | Ｎ－（２－（４－シアノチアゾリジン－３－イル）－２－オキソエチル）－キノリン－４－カルボキサミド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023554405A JP2023554405A (ja) | 2023-12-27 |
| JP2023554405A5 true JP2023554405A5 (https=) | 2024-11-06 |
| JP7622229B2 JP7622229B2 (ja) | 2025-01-27 |
Family
ID=79164845
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023536454A Active JP7622229B2 (ja) | 2020-12-17 | 2021-12-16 | Ｎ－（２－（４－シアノチアゾリジン－３－イル）－２－オキソエチル）－キノリン－４－カルボキサミド |
| JP2025005438A Active JP7744538B2 (ja) | 2020-12-17 | 2025-01-15 | Ｎ－（２－（４－シアノチアゾリジン－３－イル）－２－オキソエチル）－キノリン－４－カルボキサミド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025005438A Active JP7744538B2 (ja) | 2020-12-17 | 2025-01-15 | Ｎ－（２－（４－シアノチアゾリジン－３－イル）－２－オキソエチル）－キノリン－４－カルボキサミド |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US20240101549A1 (https=) |
| EP (1) | EP4263535A1 (https=) |
| JP (2) | JP7622229B2 (https=) |
| KR (1) | KR20230122080A (https=) |
| CN (1) | CN116745291A (https=) |
| AR (1) | AR124379A1 (https=) |
| AU (2) | AU2021403827B2 (https=) |
| CA (1) | CA3204318A1 (https=) |
| CL (1) | CL2023001763A1 (https=) |
| CO (1) | CO2023008921A2 (https=) |
| CR (1) | CR20230314A (https=) |
| DO (1) | DOP2023000124A (https=) |
| EC (1) | ECSP23053033A (https=) |
| IL (1) | IL303655A (https=) |
| MX (1) | MX2023007287A (https=) |
| PE (1) | PE20232046A1 (https=) |
| SA (1) | SA523441175B1 (https=) |
| TW (1) | TW202239407A (https=) |
| UY (1) | UY39569A (https=) |
| WO (1) | WO2022130270A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4263535A1 (en) * | 2020-12-17 | 2023-10-25 | Astrazeneca AB | N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)- quinoline-4-carboxamides |
| IL317722A (en) * | 2022-06-21 | 2025-02-01 | Astrazeneca Ab | Solid state forms of N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-6-morpholinoquinoline-4-carboxamide |
| JP2025525344A (ja) * | 2022-06-21 | 2025-08-05 | アストラゼネカ・アクチエボラーグ | Ｎ－（２－（４－シアノチアゾリジン－３－イル）－２－オキソエチル）－キノリン－４－カルボキサミド |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW521072B (en) | 1997-06-02 | 2003-02-21 | Meiji Seika Kaisha | 4-quinolinol derivatives and fungicides containing the same as an active ingredient used for agriculture and horticulture |
| FR2795726A1 (fr) | 1999-06-30 | 2001-01-05 | Aventis Cropscience Sa | Nouveaux pyrazoles fongicides |
| GB9928330D0 (en) * | 1999-11-30 | 2000-01-26 | Ferring Bv | Novel antidiabetic agents |
| DE10006453A1 (de) | 2000-02-14 | 2001-08-16 | Bayer Ag | Piperidylcarbonsäuren als Integrinantagonisten |
| GB0010183D0 (en) | 2000-04-26 | 2000-06-14 | Ferring Bv | Inhibitors of dipeptidyl peptidase IV |
| GB0010188D0 (en) | 2000-04-26 | 2000-06-14 | Ferring Bv | Inhibitors of dipeptidyl peptidase IV |
| JP4101053B2 (ja) | 2000-08-10 | 2008-06-11 | 田辺三菱製薬株式会社 | プロリン誘導体及びその医薬用途 |
| JP2003026698A (ja) | 2000-09-27 | 2003-01-29 | Tokyo Inst Of Technol | 新規化合物、固定化物及び蛋白質のスクリーニング方法 |
| GB0125445D0 (en) | 2001-10-23 | 2001-12-12 | Ferring Bv | Protease Inhibitors |
| JP4184378B2 (ja) | 2003-01-31 | 2008-11-19 | 株式会社三和化学研究所 | ジペプチジルペプチダーゼｉｖを阻害する化合物 |
| EP2210607B1 (en) * | 2003-09-26 | 2011-08-17 | Exelixis Inc. | N-[3-fluoro-4-({6-(methyloxy)-7-[(3-morpholin-4-ylpropyl)oxy]quinolin-4-yl}oxy)phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide for the treatment of cancer |
| WO2005087742A1 (en) | 2004-03-08 | 2005-09-22 | Exelixis, Inc. | Metabolic kinase modulators and methods of use as pesticides |
| TWI366438B (en) | 2004-08-12 | 2012-06-21 | Ishihara Sangyo Kaisha | Fungicidal composition containing acid amide derivative |
| CA2617715A1 (en) | 2005-08-11 | 2007-02-15 | F. Hoffmann-La Roche Ag | Pharmaceutical composition comprising a dpp-iv inhibitor |
| EP1760076A1 (en) * | 2005-09-02 | 2007-03-07 | Ferring B.V. | FAP Inhibitors |
| EP2099778A2 (en) | 2006-11-21 | 2009-09-16 | Smithkline Beecham Corporation | Amido anti-viral compounds |
| AU2011225095C1 (en) | 2010-03-11 | 2017-01-19 | Sumitomo Dainippon Pharma Co., Ltd. | N-Acyl cyclic amine derivative or pharmaceutically acceptable salt thereof |
| PL2753334T3 (pl) | 2011-08-30 | 2022-12-12 | Trustees Of Tufts College | Aktywowane przez fap inhibitory proteasomu do leczenia guzów litych |
| UA110862C2 (uk) | 2011-10-07 | 2016-02-25 | Ф. Хоффманн-Ля Рош Аг | Похідні етинілу як алостеричні модулятори метаботропного рецептора глутамату mglur 5 |
| WO2013107820A1 (en) * | 2012-01-17 | 2013-07-25 | Universiteit Antwerpen | Novel fap inhibitors |
| WO2014016849A2 (en) | 2012-07-23 | 2014-01-30 | Sphaera Pharma Pvt. Ltd. | Novel triazine compounds |
| CN104945395B (zh) | 2014-03-28 | 2018-01-23 | 广东东阳光药业有限公司 | 二氢嘧啶类化合物及其在药物中的应用 |
| KR20160145803A (ko) | 2014-04-22 | 2016-12-20 | 님버스 아이리스 인코포레이티드 | Irak 억제제 및 이의 용도 |
| BR112017004612A2 (pt) | 2014-09-10 | 2018-01-30 | Epizyme, Inc. | compostos, composição farmacêutica, usos de um composto, e kit |
| WO2016061751A1 (en) * | 2014-10-22 | 2016-04-28 | Merck Sharp & Dohme Corp. | Ethyl n-boc piperidinyl pyrazolo pyridones as janus kinase inhibitors |
| WO2017189569A1 (en) | 2016-04-25 | 2017-11-02 | Trustees Of Tufts College | Multimediator dpp4 and fap inhibitors, and uses related thereto |
| AU2017326006B2 (en) | 2016-09-16 | 2021-10-28 | Vitae Pharmaceuticals, LLC. | Inhibitors of the menin-MLL interaction |
| WO2018161033A1 (en) | 2017-03-02 | 2018-09-07 | Wright, Adrian | Small molecule ire1-alpha inhibitors |
| CN108690043B (zh) | 2017-04-11 | 2019-10-18 | 东莞东阳光科研发有限公司 | 喹啉类衍生物及其制备方法和用途 |
| EP3612526A2 (en) | 2017-04-20 | 2020-02-26 | The Regents of the University of California | K-ras modulators |
| US11584744B2 (en) | 2017-06-23 | 2023-02-21 | University Of Washington | Inhibitors of type 1 methionyl-tRNA synthetase and methods of using them |
| JP7365332B2 (ja) | 2017-08-07 | 2023-10-19 | ジョイント・ストック・カンパニー “バイオキャド” | Ｃｄｋ８／１９阻害薬としての新規ヘテロ環式化合物 |
| WO2019084271A1 (en) | 2017-10-25 | 2019-05-02 | Children's Medical Center Corporation | PAPD5 INHIBITORS AND METHODS OF USE |
| US11780821B2 (en) | 2017-12-15 | 2023-10-10 | Praxis Biotech LLC | Inhibitors of fibroblast activation protein |
| CN111511729A (zh) | 2017-12-19 | 2020-08-07 | 默克专利股份公司 | Tlr7/8拮抗剂及其用途 |
| EP3749663A1 (en) | 2018-02-06 | 2020-12-16 | Universität Heidelberg | Fap inhibitor |
| CA3108099A1 (en) | 2018-07-31 | 2020-02-06 | Merck Patent Gmbh | Tlr7/8 antagonists and uses thereof |
| ES2991898T3 (es) | 2018-08-08 | 2024-12-05 | Sumitomo Pharma Co Ltd | Derivado de piperidina con puente ópticamente activo |
| KR102779601B1 (ko) | 2018-08-27 | 2025-03-12 | 스미토모 파마 가부시키가이샤 | 광학 활성인 아자비시클로환 유도체 |
| US10815241B2 (en) | 2018-08-27 | 2020-10-27 | Sumitomo Dainippon Pharma Co., Ltd. | Optically active azabicyclo ring derivative |
| US11504364B2 (en) * | 2018-12-21 | 2022-11-22 | Praxis Biotech LLC | Inhibitors of fibroblast activation protein |
| JP7618567B2 (ja) | 2019-09-27 | 2025-01-21 | 住友ファーマ株式会社 | 架橋型光学活性２級アミン誘導体 |
| EP4055014B1 (en) | 2019-11-06 | 2025-04-30 | Yuhan Corporation | PYRROLIDINE AND PIPERIDINE COMPOUNDS |
| EP4263535A1 (en) * | 2020-12-17 | 2023-10-25 | Astrazeneca AB | N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)- quinoline-4-carboxamides |
-
2021
- 2021-12-16 EP EP21834914.0A patent/EP4263535A1/en active Pending
- 2021-12-16 AR ARP210103519A patent/AR124379A1/es unknown
- 2021-12-16 PE PE2023001909A patent/PE20232046A1/es unknown
- 2021-12-16 KR KR1020237023914A patent/KR20230122080A/ko active Pending
- 2021-12-16 TW TW110147244A patent/TW202239407A/zh unknown
- 2021-12-16 UY UY0001039569A patent/UY39569A/es unknown
- 2021-12-16 AU AU2021403827A patent/AU2021403827B2/en active Active
- 2021-12-16 JP JP2023536454A patent/JP7622229B2/ja active Active
- 2021-12-16 MX MX2023007287A patent/MX2023007287A/es unknown
- 2021-12-16 US US18/257,123 patent/US20240101549A1/en active Pending
- 2021-12-16 CA CA3204318A patent/CA3204318A1/en active Pending
- 2021-12-16 WO PCT/IB2021/061839 patent/WO2022130270A1/en not_active Ceased
- 2021-12-16 IL IL303655A patent/IL303655A/en unknown
- 2021-12-16 CR CR20230314A patent/CR20230314A/es unknown
- 2021-12-16 CN CN202180084189.5A patent/CN116745291A/zh active Pending
-
2023
- 2023-06-12 US US18/332,897 patent/US11858924B2/en active Active
- 2023-06-14 DO DO2023000124A patent/DOP2023000124A/es unknown
- 2023-06-15 CL CL2023001763A patent/CL2023001763A1/es unknown
- 2023-06-15 SA SA523441175A patent/SA523441175B1/ar unknown
- 2023-07-05 CO CONC2023/0008921A patent/CO2023008921A2/es unknown
- 2023-07-14 EC ECSENADI202353033A patent/ECSP23053033A/es unknown
-
2024
- 2024-09-18 AU AU2024219819A patent/AU2024219819A1/en active Pending
-
2025
- 2025-01-15 JP JP2025005438A patent/JP7744538B2/ja active Active
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