JP2023548295A5 - - Google Patents
Info
- Publication number
- JP2023548295A5 JP2023548295A5 JP2023525517A JP2023525517A JP2023548295A5 JP 2023548295 A5 JP2023548295 A5 JP 2023548295A5 JP 2023525517 A JP2023525517 A JP 2023525517A JP 2023525517 A JP2023525517 A JP 2023525517A JP 2023548295 A5 JP2023548295 A5 JP 2023548295A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- salt
- formula
- absent
- linking group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063110837P | 2020-11-06 | 2020-11-06 | |
| US63/110,837 | 2020-11-06 | ||
| PCT/US2021/058232 WO2022098990A1 (en) | 2020-11-06 | 2021-11-05 | Targeted conjugates comprising modified sirna |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023548295A JP2023548295A (ja) | 2023-11-16 |
| JP2023548295A5 true JP2023548295A5 (https=) | 2024-11-13 |
Family
ID=81457390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023525517A Pending JP2023548295A (ja) | 2020-11-06 | 2021-11-05 | 修飾されたsiRNAを含む標的化コンジュゲート |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20240052349A1 (https=) |
| EP (1) | EP4240369A4 (https=) |
| JP (1) | JP2023548295A (https=) |
| KR (1) | KR20230104652A (https=) |
| CN (1) | CN116472063A (https=) |
| AU (1) | AU2021376390A1 (https=) |
| CA (1) | CA3199757A1 (https=) |
| IL (1) | IL302530A (https=) |
| MX (1) | MX2023005138A (https=) |
| TW (1) | TW202233243A (https=) |
| WO (1) | WO2022098990A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3020585A1 (en) * | 2016-04-11 | 2017-10-19 | Arbutus Biopharma Corporation | Targeted nucleic acid conjugate compositions |
| WO2024099316A1 (zh) * | 2022-11-08 | 2024-05-16 | 南京明德新药研发有限公司 | 含七元杂环的四价缀合基团及其应用 |
| WO2026061476A1 (zh) * | 2024-09-19 | 2026-03-26 | 长春金赛药业有限责任公司 | 一种多簇连接子、其制备方法及应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050222064A1 (en) * | 2002-02-20 | 2005-10-06 | Sirna Therapeutics, Inc. | Polycationic compositions for cellular delivery of polynucleotides |
| EP2563922A1 (en) * | 2010-04-26 | 2013-03-06 | Marina Biotech, Inc. | Nucleic acid compounds with conformationally restricted monomers and uses thereof |
| CA2996722A1 (en) * | 2015-07-17 | 2017-01-26 | Arcturus Therapeutics, Inc. | Compositions and agents against hepatitis b virus and uses thereof |
| CA3020585A1 (en) * | 2016-04-11 | 2017-10-19 | Arbutus Biopharma Corporation | Targeted nucleic acid conjugate compositions |
| MX2019012280A (es) * | 2017-04-11 | 2020-01-23 | Arbutus Biopharma Corp | Composiciones dirigidas. |
| US11324820B2 (en) * | 2017-04-18 | 2022-05-10 | Alnylam Pharmaceuticals, Inc. | Methods for the treatment of subjects having a hepatitis b virus (HBV) infection |
| JP7473472B2 (ja) * | 2017-10-17 | 2024-04-23 | アローヘッド ファーマシューティカルズ インコーポレイテッド | アシアロ糖タンパク質受容体1の発現を阻害するためのRNAi剤および組成物 |
| MA55375A (fr) * | 2019-03-20 | 2022-01-26 | Arbutus Biopharma Corp | Méthodes thérapeutiques de traitement de l'hépatite b |
-
2021
- 2021-11-05 KR KR1020237018346A patent/KR20230104652A/ko active Pending
- 2021-11-05 AU AU2021376390A patent/AU2021376390A1/en active Pending
- 2021-11-05 MX MX2023005138A patent/MX2023005138A/es unknown
- 2021-11-05 IL IL302530A patent/IL302530A/en unknown
- 2021-11-05 JP JP2023525517A patent/JP2023548295A/ja active Pending
- 2021-11-05 US US18/035,695 patent/US20240052349A1/en active Pending
- 2021-11-05 CA CA3199757A patent/CA3199757A1/en active Pending
- 2021-11-05 WO PCT/US2021/058232 patent/WO2022098990A1/en not_active Ceased
- 2021-11-05 CN CN202180078408.9A patent/CN116472063A/zh active Pending
- 2021-11-05 EP EP21890140.3A patent/EP4240369A4/en active Pending
- 2021-11-08 TW TW110141540A patent/TW202233243A/zh unknown
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