JP2022544538A5 - - Google Patents

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Publication number
JP2022544538A5
JP2022544538A5 JP2022509053A JP2022509053A JP2022544538A5 JP 2022544538 A5 JP2022544538 A5 JP 2022544538A5 JP 2022509053 A JP2022509053 A JP 2022509053A JP 2022509053 A JP2022509053 A JP 2022509053A JP 2022544538 A5 JP2022544538 A5 JP 2022544538A5
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JP
Japan
Prior art keywords
alkyl
substituted
alkoxy
independently selected
heteroaryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022509053A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022544538A (ja
JP7689110B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/046546 external-priority patent/WO2021030766A1/en
Publication of JP2022544538A publication Critical patent/JP2022544538A/ja
Publication of JP2022544538A5 publication Critical patent/JP2022544538A5/ja
Priority to JP2025087494A priority Critical patent/JP2025122671A/ja
Application granted granted Critical
Publication of JP7689110B2 publication Critical patent/JP7689110B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022509053A 2019-08-15 2020-08-14 脊髄性筋萎縮症のための併用療法 Active JP7689110B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025087494A JP2025122671A (ja) 2019-08-15 2025-05-26 脊髄性筋萎縮症のための併用療法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962887579P 2019-08-15 2019-08-15
US62/887,579 2019-08-15
PCT/US2020/046546 WO2021030766A1 (en) 2019-08-15 2020-08-14 Combination therapy for spinal muscular atrophy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025087494A Division JP2025122671A (ja) 2019-08-15 2025-05-26 脊髄性筋萎縮症のための併用療法

Publications (3)

Publication Number Publication Date
JP2022544538A JP2022544538A (ja) 2022-10-19
JP2022544538A5 true JP2022544538A5 (https=) 2023-08-22
JP7689110B2 JP7689110B2 (ja) 2025-06-05

Family

ID=74570741

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022509053A Active JP7689110B2 (ja) 2019-08-15 2020-08-14 脊髄性筋萎縮症のための併用療法
JP2025087494A Pending JP2025122671A (ja) 2019-08-15 2025-05-26 脊髄性筋萎縮症のための併用療法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025087494A Pending JP2025122671A (ja) 2019-08-15 2025-05-26 脊髄性筋萎縮症のための併用療法

Country Status (4)

Country Link
US (1) US20220280548A1 (https=)
EP (1) EP4013387A4 (https=)
JP (2) JP7689110B2 (https=)
WO (1) WO2021030766A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250206783A1 (en) * 2022-03-21 2025-06-26 Capsigen Inc. Transcription-dependent directed evolution of aav capsids having enhanced tropism
EP4601651A1 (en) * 2022-10-14 2025-08-20 Genentech, Inc. Methods for treating spinal muscular atrophy
IL326390A (en) 2023-08-10 2026-04-01 Univ Pennsylvania Compositions and methods for treating spinal muscular atrophy
CN118045206B (zh) * 2024-04-12 2024-07-05 四川至善唯新生物科技有限公司 一种治疗脊髓型肌肉萎缩的药物组合物及其用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2699827T3 (es) * 2009-06-17 2019-02-13 Biogen Ma Inc Composiciones y métodos para la modulación de corte y empalme de SMN2 en un sujeto
WO2013068441A1 (en) * 2011-11-11 2013-05-16 Santaris Pharma A/S Compounds for the modulation of smn2 splicing
SG11201407483YA (en) * 2012-05-16 2014-12-30 Rana Therapeutics Inc Compositions and methods for modulating smn gene family expression
MX380973B (es) * 2013-05-01 2025-03-12 Genzyme Corp Composiciones y metodos para tratar la atrofia muscular espinal.
JP6659841B2 (ja) * 2015-11-12 2020-03-04 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 脊髄性筋萎縮症を処置するための組成物
MX2018007234A (es) * 2015-12-14 2018-11-09 Univ Pennsylvania Vectores virales adenoasociados utiles en el tratamiento de atrofia muscular espinal.
EP3484524B1 (en) * 2016-07-15 2022-11-09 Ionis Pharmaceuticals, Inc. Compounds and methods for modulation of smn2
US20210308281A1 (en) * 2018-08-15 2021-10-07 Biogen Ma Inc. Combination therapy for spinal muscular atrophy

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