JP2025500860A5 - - Google Patents

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Publication number
JP2025500860A5
JP2025500860A5 JP2024535520A JP2024535520A JP2025500860A5 JP 2025500860 A5 JP2025500860 A5 JP 2025500860A5 JP 2024535520 A JP2024535520 A JP 2024535520A JP 2024535520 A JP2024535520 A JP 2024535520A JP 2025500860 A5 JP2025500860 A5 JP 2025500860A5
Authority
JP
Japan
Prior art keywords
seq
dsrna
antisense strand
sense strand
nucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024535520A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025500860A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2022/139488 external-priority patent/WO2023109938A1/zh
Publication of JP2025500860A publication Critical patent/JP2025500860A/ja
Publication of JP2025500860A5 publication Critical patent/JP2025500860A5/ja
Pending legal-status Critical Current

Links

JP2024535520A 2021-12-16 2022-12-16 dsRNA、その調製方法及び使用 Pending JP2025500860A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202111542797.4 2021-12-16
CN202111542797 2021-12-16
PCT/CN2022/139488 WO2023109938A1 (zh) 2021-12-16 2022-12-16 一种dsRNA、其制备方法及应用

Publications (2)

Publication Number Publication Date
JP2025500860A JP2025500860A (ja) 2025-01-15
JP2025500860A5 true JP2025500860A5 (https=) 2025-12-26

Family

ID=86774893

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024535520A Pending JP2025500860A (ja) 2021-12-16 2022-12-16 dsRNA、その調製方法及び使用

Country Status (6)

Country Link
JP (1) JP2025500860A (https=)
KR (1) KR20240116537A (https=)
CN (1) CN118302526A (https=)
CA (1) CA3240651A1 (https=)
TW (1) TW202334425A (https=)
WO (1) WO2023109938A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024125636A1 (zh) * 2022-12-16 2024-06-20 上海拓界生物医药科技有限公司 Toll样受体调节剂与dsRNA的联合治疗
CN119816597A (zh) * 2023-08-10 2025-04-11 石药集团中奇制药技术(石家庄)有限公司 一种抑制HBV基因表达的dsRNA分子及其应用
CN116854754B (zh) 2023-09-01 2023-12-12 北京悦康科创医药科技股份有限公司 一种含有核糖环或其衍生结构的GalNAc化合物及其寡核苷酸缀合物
CN118638166B (zh) 2024-08-15 2024-12-17 北京悦康科创医药科技股份有限公司 含有三氮唑结构的GalNAc化合物及其寡核苷酸缀合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101773551B1 (ko) * 2008-10-15 2017-08-31 아이오니스 파마수티컬즈, 인코포레이티드 인자 11 발현의 조정
EA024762B9 (ru) * 2011-06-30 2017-04-28 Эрроухэд Рисерч Корпорейшн Композиции и способы ингибирования экспрессии генов вируса гепатита в
EP3719127A4 (en) * 2017-12-01 2021-10-20 Suzhou Ribo Life Science Co., Ltd. NUCLEIC ACID, COMPOSITION AND CONJUGATE WITH IT, MANUFACTURING METHOD AND USE
CN111378655B (zh) * 2018-12-28 2024-03-19 苏州瑞博生物技术股份有限公司 抑制CTGF基因表达的siRNA、含有该siRNA的药物组合物及其用途
AU2020280439B2 (en) * 2019-05-22 2025-08-14 Suzhou Ribo Life Science Co., Ltd. Nucleic acid, pharmaceutical composition, conjugate, preparation method, and use
KR20220011689A (ko) * 2019-05-22 2022-01-28 쑤저우 리보 라이프 사이언스 컴퍼니, 리미티드 핵산, 약제학적 조성물, 접합체, 제조 방법, 및 용도

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