JP2023505434A5 - - Google Patents

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Publication number
JP2023505434A5
JP2023505434A5 JP2022532614A JP2022532614A JP2023505434A5 JP 2023505434 A5 JP2023505434 A5 JP 2023505434A5 JP 2022532614 A JP2022532614 A JP 2022532614A JP 2022532614 A JP2022532614 A JP 2022532614A JP 2023505434 A5 JP2023505434 A5 JP 2023505434A5
Authority
JP
Japan
Prior art keywords
compound according
group
alkyl
salt
independently selected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022532614A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023505434A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/063617 external-priority patent/WO2021113820A1/en
Publication of JP2023505434A publication Critical patent/JP2023505434A/ja
Publication of JP2023505434A5 publication Critical patent/JP2023505434A5/ja
Pending legal-status Critical Current

Links

JP2022532614A 2019-12-06 2020-12-07 肝線維症を治療するためのコンジュゲート及び方法 Pending JP2023505434A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962944963P 2019-12-06 2019-12-06
US62/944,963 2019-12-06
PCT/US2020/063617 WO2021113820A1 (en) 2019-12-06 2020-12-07 Conjugates and methods for treating liver fibrosis

Publications (2)

Publication Number Publication Date
JP2023505434A JP2023505434A (ja) 2023-02-09
JP2023505434A5 true JP2023505434A5 (https=) 2023-12-13

Family

ID=76222671

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022532614A Pending JP2023505434A (ja) 2019-12-06 2020-12-07 肝線維症を治療するためのコンジュゲート及び方法

Country Status (12)

Country Link
US (1) US20220387600A1 (https=)
EP (1) EP4069276A4 (https=)
JP (1) JP2023505434A (https=)
KR (1) KR20220112788A (https=)
CN (1) CN115884984A (https=)
AU (1) AU2020398708A1 (https=)
BR (1) BR112022010613A2 (https=)
CA (1) CA3163911A1 (https=)
IL (1) IL293560A (https=)
MX (1) MX2022006846A (https=)
NZ (1) NZ788988A (https=)
WO (1) WO2021113820A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3020585A1 (en) * 2016-04-11 2017-10-19 Arbutus Biopharma Corporation Targeted nucleic acid conjugate compositions
CN118234862A (zh) * 2021-09-08 2024-06-21 阿利戈斯治疗公司 经修饰的短干扰核酸分子(siNA)及其用途
WO2024175062A1 (zh) * 2023-02-23 2024-08-29 大睿生物医药科技(上海)有限公司 调控KHK基因活性的dsRNA分子
US20240352464A1 (en) * 2023-03-07 2024-10-24 Aligos Therapeutics, Inc. Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof
CN119219716A (zh) * 2023-06-30 2024-12-31 上海维申医药有限公司 新型GalNAc的靶向递送片段及其制备和应用
WO2025255972A1 (zh) * 2024-06-13 2025-12-18 广州必贝特医药股份有限公司 用于靶向递送寡核苷酸药物的化合物、缀合物及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3020585A1 (en) * 2016-04-11 2017-10-19 Arbutus Biopharma Corporation Targeted nucleic acid conjugate compositions
MX2019012280A (es) * 2017-04-11 2020-01-23 Arbutus Biopharma Corp Composiciones dirigidas.
WO2019051257A2 (en) * 2017-09-11 2019-03-14 Arbutus Biopharma Corporation METHODS OF TREATING HEPATITIS B TYPE INFECTIONS
AU2019239971B2 (en) * 2018-03-21 2025-09-11 Regeneron Pharmaceuticals, Inc. 17beta-hydroxysteroid dehydrogenase type 13 (HSD17b13) iRNA compositions and methods of use thereof
EP3873530A4 (en) * 2018-11-02 2022-11-09 Genevant Sciences GmbH THERAPEUTIC PROCESSES

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