JP2022522486A5 - - Google Patents
Info
- Publication number
- JP2022522486A5 JP2022522486A5 JP2021551785A JP2021551785A JP2022522486A5 JP 2022522486 A5 JP2022522486 A5 JP 2022522486A5 JP 2021551785 A JP2021551785 A JP 2021551785A JP 2021551785 A JP2021551785 A JP 2021551785A JP 2022522486 A5 JP2022522486 A5 JP 2022522486A5
- Authority
- JP
- Japan
- Prior art keywords
- body weight
- days
- approximately
- ring
- membered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2019/076688 | 2019-03-01 | ||
| CN2019076688 | 2019-03-01 | ||
| PCT/CN2020/076723 WO2020177587A1 (zh) | 2019-03-01 | 2020-02-26 | 治疗脂肪性肝病和/或脂肪性肝炎的方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022522486A JP2022522486A (ja) | 2022-04-19 |
| JP2022522486A5 true JP2022522486A5 (https=) | 2023-03-06 |
| JP7565292B2 JP7565292B2 (ja) | 2024-10-10 |
Family
ID=72337009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021551785A Active JP7565292B2 (ja) | 2019-03-01 | 2020-02-26 | 脂肪性肝疾患および／または脂肪性肝炎の処置方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US12485108B2 (https=) |
| EP (1) | EP3932404A4 (https=) |
| JP (1) | JP7565292B2 (https=) |
| KR (1) | KR102906316B1 (https=) |
| CN (1) | CN113490493B (https=) |
| AU (1) | AU2020230574B2 (https=) |
| BR (1) | BR112021017354A2 (https=) |
| CA (1) | CA3132228A1 (https=) |
| IL (1) | IL285989B2 (https=) |
| TW (1) | TWI852999B (https=) |
| WO (1) | WO2020177587A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230061444A (ko) * | 2020-08-31 | 2023-05-08 | 베이징 타이드 파마슈티컬 코퍼레이션 리미티드 | Rho-연관 단백질 인산화효소 억제제의 염, 염의 고체 형태, 이의 제조 방법 및 이의 용도 |
| CN113135900B (zh) * | 2021-03-12 | 2022-05-24 | 中山大学 | 吲哚嘧啶类化合物及其合成方法和应用 |
| EP4393917A4 (en) * | 2021-09-18 | 2025-09-10 | Beijing Tide Pharmaceutical Co Ltd | SOLID FORM OF A RHO-ASSOCIATED PROTEIN KINASE INHIBITOR OR SOLVATE THEREOF, METHOD OF PREPARATION AND USE THEREOF |
| CN118215468A (zh) * | 2021-11-16 | 2024-06-18 | 北京泰德制药股份有限公司 | 一种rock2抑制剂的纳米晶制剂及其制备方法 |
| CA3254208A1 (en) * | 2022-03-14 | 2023-09-21 | Purdue Research Foundation | SPLEEN TYROSINE KINASE INHIBITOR, COMPOSITION AND METHODS OF USE |
| CN117843618A (zh) * | 2022-08-29 | 2024-04-09 | 北京沐华生物科技有限责任公司 | 一种ep300/cbp调节剂及其制备方法和用途 |
| WO2025017500A1 (en) | 2023-07-17 | 2025-01-23 | Graviton Bioscience Bv | Formulations of rock2 inhibitors for cns disorders |
| WO2025017499A1 (en) | 2023-07-17 | 2025-01-23 | Graviton Bioscience Bv | Formulations and uses of rock2 inhibitors for als |
| CN117122602B (zh) * | 2023-09-26 | 2026-03-20 | 赣南创新与转化医学研究院 | 化合物在制备治疗和/或预防脂肪肝病及相关疾病的药物中的用途 |
| WO2025069008A1 (en) | 2023-09-28 | 2025-04-03 | Graviton Bioscience Bv | Therapy for treating type 1 diabetes using rock2 and dyrk1 inhibitors |
| WO2025069009A1 (en) | 2023-09-29 | 2025-04-03 | Graviton Bioscience Bv | Rock2 inhibitors in the treatment of obesity |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012040499A2 (en) * | 2010-09-22 | 2012-03-29 | Surface Logix, Inc. | Metabolic inhibitors |
| FR3017868A1 (fr) | 2014-02-21 | 2015-08-28 | Servier Lab | Derives d'isoquinoleine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| WO2016004254A1 (en) * | 2014-07-01 | 2016-01-07 | The Regents Of The University Of California | Combined modulation of ire1 |
| EP3504204A4 (en) | 2016-08-26 | 2020-05-27 | Lycera Corporation | INDAZOLYL-L, 2,4-THIADIAZOLAMINE AND RELATED COMPOUNDS FOR INHIBITING RHO-ASSOCIATED PROTEIN KINASES AND FOR TREATING DISEASES |
| JP7311228B2 (ja) * | 2017-06-30 | 2023-07-19 | ベイジン タイド ファーマシューティカル カンパニー リミテッド | Ｒｈｏ－関連プロテインキナーゼ阻害剤、それを含む医薬組成物並びにその調製方法及び使用 |
| CN110582491B (zh) * | 2017-06-30 | 2023-09-29 | 北京泰德制药股份有限公司 | Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途 |
| KR102563325B1 (ko) * | 2017-06-30 | 2023-08-03 | 베이징 타이드 파마슈티컬 코퍼레이션 리미티드 | Ｒｈｏ-관련 단백질 키나아제 억제제, Ｒｈｏ-관련 단백질 키나아제 억제제를 함유하는 약학 조성물, 제조 방법 및 약학 조성물의 용도 |
| GB201801226D0 (en) | 2018-01-25 | 2018-03-14 | Redx Pharma Plc | Modulators of Rho-associated protein kinase |
-
2020
- 2020-02-26 BR BR112021017354A patent/BR112021017354A2/pt unknown
- 2020-02-26 IL IL285989A patent/IL285989B2/en unknown
- 2020-02-26 EP EP20765982.2A patent/EP3932404A4/en active Pending
- 2020-02-26 AU AU2020230574A patent/AU2020230574B2/en active Active
- 2020-02-26 CN CN202080017129.7A patent/CN113490493B/zh active Active
- 2020-02-26 CA CA3132228A patent/CA3132228A1/en active Pending
- 2020-02-26 US US17/435,061 patent/US12485108B2/en active Active
- 2020-02-26 JP JP2021551785A patent/JP7565292B2/ja active Active
- 2020-02-26 WO PCT/CN2020/076723 patent/WO2020177587A1/zh not_active Ceased
- 2020-02-26 KR KR1020217031621A patent/KR102906316B1/ko active Active
- 2020-02-27 TW TW109106569A patent/TWI852999B/zh active
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