|
HUT73101A
(en)
|
1993-02-12 |
1996-06-28 |
Harvard College |
Method for regulating transcription of targeted genes and other biological events
|
|
ATE544776T1
(de)
|
1994-12-29 |
2012-02-15 |
Massachusetts Inst Technology |
Chimäre dna-bindeproteine
|
|
KR19990022651A
(ko)
|
1995-06-07 |
1999-03-25 |
데이비드 엘. 버스테인 |
생물학적 사건에 대한 라파마이신 기재 조절방법
|
|
JP2003524368A
(ja)
|
1997-08-26 |
2003-08-19 |
アリアド ジーン セラピューティクス インコーポレイテッド |
ニ量化ドメイン、三量化ドメインまたは四量化ドメインおよび補足的非相同転写活性化ドメイン、転写抑制ドメイン、ｄｎａ結合ドメインまたはリガンド結合ドメインを含む融合蛋白
|
|
IL134643A0
(en)
|
1997-08-27 |
2001-04-30 |
Ariad Gene Therapeutics Inc |
Chimeric transcriptional activators and compositions and uses related thereto
|
|
WO1999036553A2
(en)
|
1998-01-15 |
1999-07-22 |
Ariad Gene Therapeutics, Inc. |
Regulation of biological events using multimeric chimeric proteins
|
|
JP2002503667A
(ja)
|
1998-02-13 |
2002-02-05 |
プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ |
新規な二量体化剤、その製造および使用
|
|
US6596535B1
(en)
|
1999-08-09 |
2003-07-22 |
Targeted Genetics Corporation |
Metabolically activated recombinant viral vectors and methods for the preparation and use
|
|
US7067526B1
(en)
|
1999-08-24 |
2006-06-27 |
Ariad Gene Therapeutics, Inc. |
28-epirapalogs
|
|
CN103589692B
(zh)
|
2001-11-13 |
2018-07-24 |
宾夕法尼亚大学托管会 |
检测和/或鉴定腺伴随病毒(aav)序列以及分离所鉴定的新型序列的方法
|
|
DK2359869T3
(en)
|
2001-12-17 |
2019-04-15 |
Univ Pennsylvania |
Sequences of adeno-associated virus (AAV) serotype 8, vectors containing these, and uses thereof
|
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
|
US8399618B2
(en)
|
2004-10-21 |
2013-03-19 |
Xencor, Inc. |
Immunoglobulin insertions, deletions, and substitutions
|
|
EP1668143B1
(en)
|
2003-09-30 |
2013-03-20 |
The Trustees of The University of Pennsylvania |
Adeno-associated virus (aav) clades, sequences, vectors containing same, and uses therefor
|
|
US8367805B2
(en)
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US20070135620A1
(en)
|
2004-11-12 |
2007-06-14 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US7183969B2
(en)
|
2004-12-22 |
2007-02-27 |
Raytheon Company |
System and technique for calibrating radar arrays
|
|
AU2006230419A1
(en)
*
|
2005-03-31 |
2006-10-05 |
Targeted Genetics Corporation |
Methods for lowering the level of tumor necrosis factor (TNF) in TNF-associated disorders
|
|
DE23193606T1
(de)
|
2005-04-07 |
2024-02-15 |
The Trustees Of The University Of Pennsylvania |
Verfahren zur erhöhung der funktion eines aav-vektors
|
|
JP4495210B2
(ja)
|
2005-06-09 |
2010-06-30 |
パナソニック株式会社 |
振幅誤差補償装置及び直交度誤差補償装置
|
|
US7846724B2
(en)
|
2006-04-11 |
2010-12-07 |
Hoffmann-La Roche Inc. |
Method for selecting CHO cell for production of glycosylated antibodies
|
|
WO2009052140A1
(en)
*
|
2007-10-15 |
2009-04-23 |
Alcon Research, Ltd. |
Use of tnf receptor antagonists for treating dry eye
|
|
AU2009215987B2
(en)
|
2008-02-19 |
2015-01-22 |
Uniqure Ip B.V. |
Optimisation of expression of parvoviral rep and cap proteins in insect cells
|
|
DK2425000T3
(da)
|
2009-04-30 |
2019-05-13 |
Univ Pennsylvania |
Sammensætninger rettet mod ledende luftvejsceller omfattende konstrukter af adeno-associeret virus
|
|
US8734809B2
(en)
|
2009-05-28 |
2014-05-27 |
University Of Massachusetts |
AAV's and uses thereof
|
|
US10053513B2
(en)
|
2009-11-30 |
2018-08-21 |
Janssen Biotech, Inc. |
Antibody Fc mutants with ablated effector functions
|
|
US8927514B2
(en)
|
2010-04-30 |
2015-01-06 |
City Of Hope |
Recombinant adeno-associated vectors for targeted treatment
|
|
US8628966B2
(en)
|
2010-04-30 |
2014-01-14 |
City Of Hope |
CD34-derived recombinant adeno-associated vectors for stem cell transduction and systemic therapeutic gene transfer
|
|
US10738326B2
(en)
|
2010-10-27 |
2020-08-11 |
Jichi Medical University |
Adeno-associated virus vector for gene transfer to nervous system cells
|
|
CA2826273C
(en)
|
2011-02-10 |
2021-11-02 |
The University Of North Carolina At Chapel Hill |
Viral vectors with modified transduction profiles and methods of making and using the same
|
|
DK3693025T3
(da)
|
2011-04-22 |
2022-01-10 |
Univ California |
Adenoassocierede virus-virioner med variant capsid og fremgangsmåder til anvendelse heraf
|
|
EP3795581A3
(en)
|
2011-08-24 |
2021-06-09 |
The Board of Trustees of the Leland Stanford Junior University |
New avv capsid proteins for nucleic acid transfer
|
|
US9382319B2
(en)
|
2011-09-26 |
2016-07-05 |
Jn Biosciences Llc |
Hybrid constant regions
|
|
EP3470523A1
(en)
|
2012-05-09 |
2019-04-17 |
Oregon Health & Science University |
Adeno associated virus plasmids and vectors
|
|
GB2510803B
(en)
|
2012-11-13 |
2015-07-22 |
Cardiff Metropolitan University |
Trocar assembly
|
|
CN103045646B
(zh)
*
|
2012-12-27 |
2015-02-25 |
中国人民解放军军事医学科学院基础医学研究所 |
共表达两个独立的抗关节炎分子TNFR-Fc和CTLA4-FasL的重组腺相关病毒载体及其构建方法与应用
|
|
CN103131676A
(zh)
*
|
2013-01-04 |
2013-06-05 |
天津耀宇生物技术有限公司 |
表达重组人肿瘤坏死因子受体-Fc融合蛋白基因的家蚕重组杆状病毒及其制备方法和应用
|
|
TWI682941B
(zh)
|
2013-02-01 |
2020-01-21 |
美商再生元醫藥公司 |
含嵌合恆定區之抗體
|
|
EP2970946A4
(en)
|
2013-03-13 |
2016-09-07 |
Philadelphia Children Hospital |
ADENOASSOZED VIRUS VECTORS AND METHOD FOR USE THEREOF
|
|
US9862945B2
(en)
|
2013-04-20 |
2018-01-09 |
Research Institute At Nationwide Children's Hospital |
Recombinant adeno-associated virus delivery of exon 2-targeted U7SNRNA polynucleotide constructs
|
|
NZ716102A
(en)
|
2013-07-22 |
2021-12-24 |
The Children’S Hospital Of Philadelphia |
Variant aav and compositions, methods and uses for gene transfer to cells, organs and tissues
|
|
EP3564379A1
(en)
|
2013-09-13 |
2019-11-06 |
California Institute of Technology |
Selective recovery
|
|
HUE052676T2
(hu)
|
2013-10-11 |
2021-05-28 |
Massachusetts Eye & Ear Infirmary |
Eljárások õsi vírusszekvenciák elõrejelzésére és alkalmazásaik
|
|
US10746742B2
(en)
|
2014-04-25 |
2020-08-18 |
Oregon Health & Science University |
Methods of viral neutralizing antibody epitope mapping
|
|
US10577627B2
(en)
|
2014-06-09 |
2020-03-03 |
Voyager Therapeutics, Inc. |
Chimeric capsids
|
|
US10000551B2
(en)
*
|
2014-09-11 |
2018-06-19 |
Protalix Ltd. |
Chimeric polypeptides, polynucleotides encoding same, cells expressing same and methods of producing same
|
|
WO2016049230A1
(en)
|
2014-09-24 |
2016-03-31 |
City Of Hope |
Adeno-associated virus vector variants for high efficiency genome editing and methods thereof
|
|
FR3031112B1
(fr)
*
|
2014-12-24 |
2018-05-25 |
Eyevensys |
Construction d'adn pour le traitement de pathologies oculaires
|
|
DK3277725T3
(da)
|
2015-03-30 |
2021-01-11 |
Regeneron Pharma |
Konstante tungkædeområder med reduceret binding til FC-gammareceptorer
|
|
JP6665466B2
(ja)
|
2015-09-26 |
2020-03-13 |
日亜化学工業株式会社 |
半導体発光素子及びその製造方法
|
|
WO2017070491A1
(en)
|
2015-10-23 |
2017-04-27 |
Applied Genetic Technologies Corporation |
Ophthalmic formulations
|
|
IL262207B2
(en)
*
|
2016-04-15 |
2026-01-01 |
Univ Pennsylvania |
Preparations for the treatment of wet age-related macular degeneration
|
|
AU2017345470B2
(en)
|
2016-10-19 |
2023-08-03 |
Adverum Biotechnologies, Inc. |
Modified AAV capsids and uses thereof
|
|
KR20200067195A
(ko)
*
|
2017-10-18 |
2020-06-11 |
리젠엑스바이오 인크. |
완전-인간 번역후 변형된 항체 치료제
|