JP2023541203A5 - - Google Patents

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Publication number
JP2023541203A5
JP2023541203A5 JP2023517268A JP2023517268A JP2023541203A5 JP 2023541203 A5 JP2023541203 A5 JP 2023541203A5 JP 2023517268 A JP2023517268 A JP 2023517268A JP 2023517268 A JP2023517268 A JP 2023517268A JP 2023541203 A5 JP2023541203 A5 JP 2023541203A5
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JP
Japan
Prior art keywords
pharmaceutically acceptable
stereoisomer
acceptable salt
compound according
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023517268A
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English (en)
Japanese (ja)
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JP2023541203A (ja
JP7824938B2 (ja
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Publication date
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Priority claimed from PCT/US2021/050649 external-priority patent/WO2022060973A1/en
Publication of JP2023541203A publication Critical patent/JP2023541203A/ja
Publication of JP2023541203A5 publication Critical patent/JP2023541203A5/ja
Application granted granted Critical
Publication of JP7824938B2 publication Critical patent/JP7824938B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2023517268A 2020-09-16 2021-09-16 Tyk2阻害剤およびその使用 Active JP7824938B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063079217P 2020-09-16 2020-09-16
US63/079,217 2020-09-16
PCT/US2021/050649 WO2022060973A1 (en) 2020-09-16 2021-09-16 Tyk2 inhibitors and uses thereof

Publications (3)

Publication Number Publication Date
JP2023541203A JP2023541203A (ja) 2023-09-28
JP2023541203A5 true JP2023541203A5 (https=) 2024-09-17
JP7824938B2 JP7824938B2 (ja) 2026-03-05

Family

ID=78086111

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023517268A Active JP7824938B2 (ja) 2020-09-16 2021-09-16 Tyk2阻害剤およびその使用

Country Status (9)

Country Link
US (1) US20230357273A1 (https=)
EP (1) EP4214215A1 (https=)
JP (1) JP7824938B2 (https=)
KR (1) KR20230069984A (https=)
CN (1) CN117279922B (https=)
AU (1) AU2021345181A1 (https=)
CA (1) CA3192621A1 (https=)
IL (1) IL301385A (https=)
WO (1) WO2022060973A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4423086A1 (en) 2021-10-25 2024-09-04 Kymera Therapeutics, Inc. Tyk2 degraders and uses thereof
CA3245808A1 (en) * 2022-03-16 2023-09-21 Alumis Inc. TYK2 INHIBITORS AND THEIR USES
CN119487037A (zh) * 2022-03-16 2025-02-18 阿鲁米斯股份有限公司 Tyk2抑制剂及其用途
WO2023208244A1 (zh) * 2022-04-29 2023-11-02 南京明德新药研发有限公司 大环类化合物及其应用
JP2026512838A (ja) 2023-03-31 2026-04-21 北京普祺医薬科技股▲分▼有限公司 大環化合物、医薬組成物及びその使用
WO2024222807A1 (en) * 2023-04-27 2024-10-31 Hangzhou Highlightll Pharmaceutical Co., Ltd Novel macrocyclic heteroaryl derivatives as kinase inhibitors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016287568B2 (en) 2015-07-02 2020-08-20 Turning Point Therapeutics, Inc. Chiral diaryl macrocycles as modulators of protein kinases
US10479793B2 (en) * 2015-11-18 2019-11-19 Bristol-Myers Squibb Company Imidazopyridazine compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses
ES2902995T3 (es) * 2016-10-07 2022-03-30 Bristol Myers Squibb Co Compuestos de imidazopiridazina útiles como moduladores de respuestas a IL-12, IL-23 y/o IFN alfa
TWI808958B (zh) 2017-01-25 2023-07-21 美商特普醫葯公司 涉及二芳基巨環化合物之組合療法
CN113348021B (zh) * 2019-01-23 2025-07-11 武田药品工业株式会社 Tyk2抑制剂和其用途
JP2022519696A (ja) * 2019-02-07 2022-03-24 ベンティックス バイオサイエンシーズ,インク. Tyk2偽キナーゼリガンド
CA3132632A1 (en) * 2019-03-11 2020-09-17 Esker Therapeutics, Inc. Tyk2 inhibitors and uses thereof
CA3134814A1 (en) 2019-03-26 2020-10-01 Ventyx Biosciences, Inc. Tyk2 pseudokinase ligands

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