|
US5139941A
(en)
|
1985-10-31 |
1992-08-18 |
University Of Florida Research Foundation, Inc. |
AAV transduction vectors
|
|
US4861719A
(en)
|
1986-04-25 |
1989-08-29 |
Fred Hutchinson Cancer Research Center |
DNA constructs for retrovirus packaging cell lines
|
|
EP0377676B1
(en)
|
1987-09-17 |
1995-05-24 |
Massachusetts Institute Of Technology |
Human erythroid-specific transcriptional enhancer
|
|
US5278056A
(en)
|
1988-02-05 |
1994-01-11 |
The Trustees Of Columbia University In The City Of New York |
Retroviral packaging cell lines and process of using same
|
|
US5670488A
(en)
|
1992-12-03 |
1997-09-23 |
Genzyme Corporation |
Adenovirus vector for gene therapy
|
|
AU8200191A
(en)
|
1990-07-09 |
1992-02-04 |
United States of America, as represented by the Secretary, U.S. Department of Commerce, The |
High efficiency packaging of mutant adeno-associated virus using amber suppressions
|
|
US5173414A
(en)
|
1990-10-30 |
1992-12-22 |
Applied Immune Sciences, Inc. |
Production of recombinant adeno-associated virus vectors
|
|
WO1993003769A1
(en)
|
1991-08-20 |
1993-03-04 |
THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPARTEMENT OF HEALTH AND HUMAN SERVICES |
Adenovirus mediated transfer of genes to the gastrointestinal tract
|
|
DE69434860T2
(de)
|
1993-02-22 |
2007-03-15 |
The Rockefeller University |
Herstellung von helfer-freien retroviren mit hohem titer mittels transienter transfektion
|
|
FR2705361B1
(fr)
|
1993-05-18 |
1995-08-04 |
Centre Nat Rech Scient |
Vecteurs viraux et utilisation en thérapie génique.
|
|
FR2712812B1
(fr)
|
1993-11-23 |
1996-02-09 |
Centre Nat Rech Scient |
Composition pour la production de produits thérapeutiques in vivo.
|
|
IL116816A
(en)
|
1995-01-20 |
2003-05-29 |
Rhone Poulenc Rorer Sa |
Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof
|
|
US6013516A
(en)
|
1995-10-06 |
2000-01-11 |
The Salk Institute For Biological Studies |
Vector and method of use for nucleic acid delivery to non-dividing cells
|
|
US6004797A
(en)
|
1995-11-09 |
1999-12-21 |
Avigen, Inc. |
Adenovirus helper-free recombinant AAV Virion production
|
|
US6027721A
(en)
|
1996-05-20 |
2000-02-22 |
Cytotherapeutics, Inc. |
Device and method for encapsulated gene therapy
|
|
US6136597A
(en)
|
1997-09-18 |
2000-10-24 |
The Salk Institute For Biological Studies |
RNA export element
|
|
US20020065236A1
(en)
|
1998-09-09 |
2002-05-30 |
Yew Nelson S. |
CpG reduced plasmids and viral vectors
|
|
US7994278B1
(en)
|
1999-08-06 |
2011-08-09 |
Nobel Biosciences Llc |
Biologically active polypeptides derived from a novel early stage pregnancy factor designated maternin (MA)
|
|
WO2001027304A2
(en)
|
1999-10-12 |
2001-04-19 |
Institut Pasteur |
Lentiviral triplex dna, and vectors and recombinant cells containing lentiviral triplex dna
|
|
AU2001255575B2
(en)
|
2000-04-28 |
2006-08-31 |
The Trustees Of The University Of Pennsylvania |
Recombinant aav vectors with aav5 capsids and aav5 vectors pseudotyped in heterologous capsids
|
|
US6627442B1
(en)
|
2000-08-31 |
2003-09-30 |
Virxsys Corporation |
Methods for stable transduction of cells with hiv-derived viral vectors
|
|
US20070037165A1
(en)
*
|
2000-09-08 |
2007-02-15 |
Applera Corporation |
Polymorphisms in known genes associated with human disease, methods of detection and uses thereof
|
|
GB0024550D0
(OSRAM)
|
2000-10-06 |
2000-11-22 |
Oxford Biomedica Ltd |
|
|
US7575924B2
(en)
|
2000-11-13 |
2009-08-18 |
Research Development Foundation |
Methods and compositions relating to improved lentiviral vectors and their applications
|
|
WO2003012054A2
(en)
|
2001-08-02 |
2003-02-13 |
Institut Clayton De La Recherche |
Methods and compositions relating to improved lentiviral vector production systems
|
|
CA2462628C
(en)
|
2001-10-02 |
2019-08-20 |
Institut Clayton De La Recherche |
Restricted expression lentiviral vectors
|
|
SG10202108118RA
(en)
|
2001-11-13 |
2021-08-30 |
Univ Pennsylvania |
A method of detecting and/or identifying adeno-associated virus (aav) sequences and isolating novel sequences identified thereby
|
|
CA2483915A1
(en)
|
2002-05-02 |
2003-11-13 |
University Of Rochester |
Vectors having both isoforms of b-hexosaminidase
|
|
US20070015238A1
(en)
|
2002-06-05 |
2007-01-18 |
Snyder Richard O |
Production of pseudotyped recombinant AAV virions
|
|
WO2004015106A1
(en)
|
2002-08-12 |
2004-02-19 |
UNIVERSITé DE SHERBROOKE |
Methods to reprogram splice site selection in pre-messenger rnas
|
|
DK1616012T3
(da)
|
2003-04-24 |
2008-04-21 |
San Raffaele Centro Fond |
Lentivirale vektorer bærende syntetiske bidirektionelle promotorer og anvendelser deraf
|
|
US7960100B1
(en)
*
|
2004-04-30 |
2011-06-14 |
Celera Corporation |
Colon cancer targets and uses thereof
|
|
JP2007054069A
(ja)
|
2005-08-24 |
2007-03-08 |
Medizinische Hochschule Hannover |
自己不活性化レトロウイルスベクター
|
|
WO2007120542A2
(en)
|
2006-03-30 |
2007-10-25 |
The Board Of Trustees Of The Leland Stanford Junior University |
Aav capsid library and aav capsid proteins
|
|
US8324367B2
(en)
|
2006-11-03 |
2012-12-04 |
Medtronic, Inc. |
Compositions and methods for making therapies delivered by viral vectors reversible for safety and allele-specificity
|
|
EP2333091B1
(en)
|
2007-05-29 |
2017-06-21 |
Nature Technology Corporation |
Vectors and methods for genetic immunization
|
|
US8299215B2
(en)
|
2007-07-14 |
2012-10-30 |
University Of Iowa Research Foundation |
Methods and compositions for treating brain diseases
|
|
WO2009126894A2
(en)
*
|
2008-04-11 |
2009-10-15 |
Massachusetts Eye And Ear Infirmary |
Methods and compositions for the diagnosis and treatment of angiogenic disorders
|
|
AU2010241864B2
(en)
|
2009-04-30 |
2014-02-20 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Inducible interleukin-12
|
|
DE102009021592A1
(de)
|
2009-05-15 |
2010-11-18 |
Medizinische Hochschule Hannover |
ASLV-Vektorsystem
|
|
WO2013078316A1
(en)
|
2011-11-23 |
2013-05-30 |
Nationwide Children's Hospital, Inc. |
Recombinant adeno-associated virus delivery of alpha-sarcoglycan polynucleotides
|
|
KR102057540B1
(ko)
|
2012-02-17 |
2019-12-19 |
더 칠드런스 호스피탈 오브 필라델피아 |
세포, 기관 및 조직으로의 유전자 전이를 위한 ａａｖ 벡터 조성물 및 방법
|
|
JP2015527889A
(ja)
|
2012-07-25 |
2015-09-24 |
ザ ブロード インスティテュート， インコーポレイテッド |
誘導可能なｄｎａ結合タンパク質およびゲノム撹乱ツール、ならびにそれらの適用
|
|
EP2792742A1
(en)
|
2013-04-17 |
2014-10-22 |
Universitätsklinikum Hamburg-Eppendorf (UKE) |
Gene-therapy vectors for treating cardiomyopathy
|
|
EP3564379A1
(en)
|
2013-09-13 |
2019-11-06 |
California Institute of Technology |
Selective recovery
|
|
GB201318347D0
(en)
|
2013-10-16 |
2013-11-27 |
Ucl Business Plc |
Retroviral vectors
|
|
WO2015060722A1
(en)
|
2013-10-24 |
2015-04-30 |
Uniqure Ip B.V. |
Aav-5 pseudotyped vector for gene therapy for neurological diseases
|
|
JP2017514476A
(ja)
|
2014-05-01 |
2017-06-08 |
ユニバーシティ・オブ・ワシントン |
アデノウイルスベクターを用いたインビボでの遺伝子操作
|
|
EP3137497B2
(en)
|
2014-05-02 |
2025-03-05 |
Genzyme Corporation |
Aav vectors for retinal and cns gene therapy
|
|
US11030531B2
(en)
|
2014-06-06 |
2021-06-08 |
Trustees Of Boston University |
DNA recombinase circuits for logical control of gene expression
|
|
WO2015196179A1
(en)
|
2014-06-20 |
2015-12-23 |
University Of Florida Research Foundation, Inc. |
Methods of packaging multiple adeno-associated virus vectors
|
|
MA41346A
(fr)
|
2015-01-12 |
2017-11-21 |
Juno Therapeutics Inc |
Eléments régulateurs post-transcriptionnels d'hépatite modifiée
|
|
JP6734283B2
(ja)
|
2015-01-21 |
2020-08-05 |
フレッド ハッチンソン キャンサー リサーチ センター |
遺伝子治療用ポイントオブケア及び／又はポータブルプラットフォーム
|
|
ES2836258T3
(es)
|
2015-03-10 |
2021-06-24 |
Univ Columbia |
Construcciones de vectores virales adenoasociados de GLUT1 recombinante y métodos relacionados para restaurar la expresión de GLUT1
|
|
EA201792500A1
(ru)
|
2015-05-13 |
2018-04-30 |
Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания |
Aav-опосредованная экспрессия антител против гриппа и способы их использования
|
|
SG11201803934YA
(en)
*
|
2015-11-11 |
2018-06-28 |
Intrexon Corp |
Compositions and methods for expression of multiple biologically active polypeptides from a single vector for treatment of cardiac conditions and other pathologies
|
|
EP3875593A1
(en)
|
2015-12-11 |
2021-09-08 |
California Institute of Technology |
Targeting peptides for directing adeno-associated viruses (aavs)
|
|
PL3405215T3
(pl)
|
2016-01-19 |
2022-10-31 |
The Regents Of The University Of California |
Sposoby leczenia choroby danona i innych zaburzeń autofagii
|
|
WO2017136536A1
(en)
|
2016-02-02 |
2017-08-10 |
University Of Massachusetts |
Method to enhance the efficiency of systemic aav gene delivery to the central nervous system
|
|
CN109641063B
(zh)
|
2016-04-20 |
2022-11-15 |
能源环境和技术研究中心O.A., M.P. |
用于增强pklr的基因表达的组合物和方法
|
|
MX2019002699A
(es)
|
2016-09-08 |
2019-12-16 |
Centro De Investig Energeticas Medioambientales Y Tecnologicas O A M P |
Terapia genica para pacientes con anemia de fanconi.
|
|
WO2018060097A1
(en)
|
2016-09-30 |
2018-04-05 |
Laboratorios Del Dr. Esteve, S. A. |
Adenoassociated virus vectors for the treatment of mucopolysaccharidoses
|
|
US20180326022A1
(en)
|
2017-04-21 |
2018-11-15 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for improving heart function and treating heart failure
|
|
JP2020517720A
(ja)
|
2017-04-27 |
2020-06-18 |
フレッド ハッチンソン キャンサー リサーチ センター |
ネガティブ選択により誘導されるｃｄ３４＋幹細胞を含む治療用製剤
|
|
CA3062595A1
(en)
|
2017-05-10 |
2018-11-15 |
The Regents Of The University Of California |
Directed editing of cellular rna via nuclear delivery of crispr/cas9
|
|
EP3684422B1
(en)
*
|
2017-09-20 |
2023-12-20 |
The Regents of the University of California |
Connexin-43 gene therapy to restore electrical and cardiac function, and cardiac structure, in arrhythmogenic right ventricular cardiomyopathy
|
|
WO2019073058A1
(en)
*
|
2017-10-12 |
2019-04-18 |
Universität Heidelberg |
GENE THERAPY OF CARDIAC ARRHYTHMIA BASED ON KCNK3
|
|
SG11202002263TA
(en)
|
2017-10-16 |
2020-04-29 |
Centro De Investigaciones Energeticas Medioambientales Y Tecnologicas |
Lentiviral vectors for delivery of pklr to treat pyruvate kinase deficiency
|
|
JP7576754B2
(ja)
|
2018-04-11 |
2024-11-01 |
スペースクラフト セブン リミテッド ライアビリティ カンパニー |
幹細胞移植のための組成物および方法
|
|
AU2019261646A1
(en)
*
|
2018-04-27 |
2020-11-12 |
Spacecraft Seven, Llc |
Gene therapy for CNS degeneration
|
|
CA3097375A1
(en)
|
2018-04-27 |
2019-10-31 |
Universitat Heidelberg |
Modified aav capsid polypeptides for treatment of muscular diseases
|
|
WO2020014523A1
(en)
|
2018-07-12 |
2020-01-16 |
Rocket Pharmaceuticals, Ltd. |
Gene therapy vectors for treatment of danon disease
|
|
MX2021001292A
(es)
|
2018-07-30 |
2021-07-15 |
Centro De Investig Energeticas Medioambientales Y Tecnologicas O A M P |
Metodos para la modificacion genica de celulas hematopoyeticas.
|
|
US12612644B2
(en)
|
2018-08-10 |
2026-04-28 |
Regenxbio Inc. |
Scalable method for recombinant AAV production
|
|
CN112770768A
(zh)
|
2018-08-16 |
2021-05-07 |
太空飞船七有限责任公司 |
用于病毒载体的生产方法
|
|
US20220088052A1
(en)
|
2019-01-22 |
2022-03-24 |
Koninklijke Nederlandse Akademie Van Wetenschappen |
Tfap2 inhibition for treating cardiac disease involving fibro-fatty replacement
|
|
CN120324641A
(zh)
*
|
2019-02-12 |
2025-07-18 |
太空飞船七有限责任公司 |
用于治疗达农病的基因治疗载体
|
|
CN113994008A
(zh)
|
2019-05-23 |
2022-01-28 |
太空飞船七有限责任公司 |
用于婴儿恶性骨硬化病的基因治疗载体
|
|
US20220389452A1
(en)
*
|
2019-09-20 |
2022-12-08 |
Ucl Business Ltd |
Gene therapy composition and treatment of right ventricular arrythmogenic cardiomyopathy
|
|
WO2021163357A2
(en)
|
2020-02-13 |
2021-08-19 |
Tenaya Therapeutics, Inc. |
Gene therapy vectors for treating heart disease
|
|
WO2021187380A1
(ja)
|
2020-03-16 |
2021-09-23 |
国立大学法人大阪大学 |
不整脈源性心筋症患者由来の多能性幹細胞およびその利用ならびに不整脈源性心筋症治療用医薬
|
|
KR20230004719A
(ko)
|
2020-04-20 |
2023-01-06 |
테나야 테라퓨틱스, 인코포레이티드 |
조작된 캡시드를 갖는 아데노-연관 바이러스
|
|
US20230174994A1
(en)
|
2020-05-20 |
2023-06-08 |
Spacecraft Seven, Llc |
Engineered parkin and uses thereof
|
|
WO2022017630A1
(en)
|
2020-07-23 |
2022-01-27 |
Ucl Business Ltd |
GENE THERAPY VECTOR FOR eEF1A2 AND USES THEREOF
|
|
WO2022031756A1
(en)
|
2020-08-05 |
2022-02-10 |
Spacecraft Seven, Llc |
Csrp3 (cysteine and glycine rich protein 3) gene therapy
|
|
JP7853952B2
(ja)
|
2020-08-05 |
2026-04-30 |
スペースクラフト セブン リミテッド ライアビリティ カンパニー |
Ｇｌｕｔ１発現のためのアデノ随伴ウイルスベクターおよびその使用
|
|
IL300263A
(en)
|
2020-08-07 |
2023-03-01 |
Spacecraft Seven Llc |
Plakophilin-2 (PKP2) gene therapy using an AAV vector
|
|
JP7415042B2
(ja)
|
2020-10-09 |
2024-01-16 |
テナヤ セラピューティクス， インコーポレイテッド |
プラコフィリン２遺伝子治療の方法および組成物
|
|
KR20230129431A
(ko)
|
2020-12-07 |
2023-09-08 |
스페이스크래프트 세븐, 엘엘씨 |
다농병의 치료
|
|
EP4308172A2
(en)
|
2021-03-19 |
2024-01-24 |
UCL Business Ltd |
Gene therapy composition and treatment of right ventricular arrhythmogenic cardiomyopathy
|
|
AU2022258329A1
(en)
|
2021-04-12 |
2023-10-12 |
The Regents Of The University Of California |
Gene therapy for arrhythmogenic right ventricular cardiomyopathy
|
|
MX2024000175A
(es)
|
2021-07-08 |
2024-03-05 |
Tenaya Therapeutics Inc |
Casetes de expresión optimizada para genoterapia.
|