JP2023537051A5 - - Google Patents
Info
- Publication number
- JP2023537051A5 JP2023537051A5 JP2023508466A JP2023508466A JP2023537051A5 JP 2023537051 A5 JP2023537051 A5 JP 2023537051A5 JP 2023508466 A JP2023508466 A JP 2023508466A JP 2023508466 A JP2023508466 A JP 2023508466A JP 2023537051 A5 JP2023537051 A5 JP 2023537051A5
- Authority
- JP
- Japan
- Prior art keywords
- heavy chain
- light chain
- antibody
- pharmaceutically acceptable
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010814877.X | 2020-08-13 | ||
| CN202010814877 | 2020-08-13 | ||
| PCT/CN2021/112462 WO2022033578A1 (zh) | 2020-08-13 | 2021-08-13 | 抗体药物偶联物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023537051A JP2023537051A (ja) | 2023-08-30 |
| JP2023537051A5 true JP2023537051A5 (https=) | 2024-08-21 |
Family
ID=80247729
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023508466A Pending JP2023537051A (ja) | 2020-08-13 | 2021-08-13 | 抗体薬物複合体 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230405141A1 (https=) |
| EP (1) | EP4183421A4 (https=) |
| JP (1) | JP2023537051A (https=) |
| KR (1) | KR20230051214A (https=) |
| CN (8) | CN119792562A (https=) |
| AU (1) | AU2021323863A1 (https=) |
| BR (1) | BR112023002417A2 (https=) |
| CA (1) | CA3188508A1 (https=) |
| IL (1) | IL300446A (https=) |
| MX (1) | MX2023001648A (https=) |
| WO (1) | WO2022033578A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI867218B (zh) * | 2020-04-30 | 2024-12-21 | 大陸商正大天晴藥業集團股份有限公司 | 靶向her2的抗原結合建構體及用途 |
| TW202320858A (zh) | 2021-07-19 | 2023-06-01 | 美商薩諾管理公司 | 免疫接合物及方法 |
| US11806405B1 (en) | 2021-07-19 | 2023-11-07 | Zeno Management, Inc. | Immunoconjugates and methods |
| JP2024533356A (ja) | 2021-09-16 | 2024-09-12 | チア タイ ティエンチン ファーマシューティカル グループ カンパニー リミテッド | 抗ｈｅｒ３抗体薬物複合体及びその組成物並びに用途 |
| EP4562051A1 (en) * | 2022-07-26 | 2025-06-04 | Immunome, Inc. | Immunoconjugates and methods |
| EP4623936A1 (en) * | 2022-11-22 | 2025-10-01 | Keymed Biosciences (Chengdu) Co., Ltd. | Fused ring compound, conjugate thereof and use thereof |
| WO2024230678A1 (zh) * | 2023-05-11 | 2024-11-14 | 映恩生物科技(上海)有限公司 | 喜树碱类化合物及其偶联物、其制备方法和用途 |
| WO2025031286A1 (zh) * | 2023-08-04 | 2025-02-13 | 映恩生物制药（苏州）有限公司 | 抗体药物偶联物的识别抗体及其应用 |
| WO2025087386A1 (zh) * | 2023-10-25 | 2025-05-01 | 正大天晴药业集团南京顺欣制药有限公司 | 抗her2抗体药物偶联物治疗乳腺癌的用途 |
| CN117257977A (zh) * | 2023-11-07 | 2023-12-22 | 正大天晴药业集团南京顺欣制药有限公司 | 用于制备抗体药物偶联物的方法 |
| WO2025131036A1 (zh) * | 2023-12-22 | 2025-06-26 | 正大天晴药业集团股份有限公司 | 靶向her2的adc治疗乳腺癌的用途 |
| WO2025155943A1 (en) * | 2024-01-18 | 2025-07-24 | Joinn Biologics Us Inc. | Immunoconjugates comprising camptothecin analogs and methods of use thereof |
| WO2025162211A1 (zh) * | 2024-01-29 | 2025-08-07 | 正大天晴药业集团股份有限公司 | 抗her2抗体药物偶联物治疗胃癌的用途 |
| WO2025162287A1 (zh) * | 2024-01-29 | 2025-08-07 | 正大天晴药业集团股份有限公司 | 抗her2抗体药物偶联物治疗肠癌的用途 |
| WO2025186213A1 (en) | 2024-03-04 | 2025-09-12 | Debiopharm International S.A. | Combination of a wee1 inhibitor and a topoisomerase 1 inhibitor |
| WO2025242061A1 (zh) * | 2024-05-21 | 2025-11-27 | 正大天晴药业集团股份有限公司 | 抗her2抗体药物偶联物治疗胆道癌的用途 |
| WO2025252039A1 (zh) * | 2024-06-03 | 2025-12-11 | 正大天晴药业集团股份有限公司 | 抗her2抗体药物偶联物治疗非小细胞肺癌的用途 |
| WO2025254460A1 (ko) * | 2024-06-07 | 2025-12-11 | ㈜지아이이노베이션 | Cd80 단백질 및 il-2 단백질을 포함하는 융합단백질 및 항체-약물 접합체를 포함하는 암 치료용 약학 조성물 |
| CN118702819B (zh) * | 2024-07-03 | 2025-10-03 | 武汉华美生物工程有限公司 | 一种抗dxd及其衍生物的抗体及其制备和应用 |
| WO2026015407A1 (en) * | 2024-07-10 | 2026-01-15 | Asieris Pharmaceuticals (Usa), Inc. | Linkers for conjugates and methods of use thereof |
| CN121466318A (zh) * | 2026-01-07 | 2026-02-06 | 哈尔滨医科大学 | 基于生物正交反应的抗体偶联药物及其制备方法与应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5945311A (en) | 1994-06-03 | 1999-08-31 | GSF--Forschungszentrumfur Umweltund Gesundheit | Method for producing heterologous bi-specific antibodies |
| DE10355904A1 (de) * | 2003-11-29 | 2005-06-30 | Merck Patent Gmbh | Feste Formen von anti-EGFR-Antikörpern |
| ES2773710T3 (es) | 2012-10-11 | 2020-07-14 | Daiichi Sankyo Co Ltd | Enlazadores para conjugados de anticuerpo - fármaco |
| KR102087850B1 (ko) * | 2013-10-11 | 2020-03-12 | 메르사나 테라퓨틱스, 인코포레이티드 | 단백질-고분자-약물 접합체 |
| AU2014357292B2 (en) * | 2013-11-27 | 2020-06-25 | Zymeworks Bc Inc. | Bispecific antigen-binding constructs targeting HER2 |
| EP3083696B1 (en) * | 2013-12-20 | 2018-02-14 | F.Hoffmann-La Roche Ag | Bispecific her2 antibodies and methods of use |
| IL310627B2 (en) * | 2014-01-31 | 2026-04-01 | Daiichi Sankyo Co Ltd | Anti-HER2 antibody-drug conjugates, compositions containing them and uses thereof |
| MX2017006016A (es) * | 2014-11-11 | 2017-06-19 | Amunix Operating Inc | Composiciones conjugadas de xten direccionadas y metodos para producir las mismas. |
| CN104610453A (zh) * | 2015-01-23 | 2015-05-13 | 张帆 | 一类抗her2双靶向抗体、其制备方法及用途 |
| WO2019034176A1 (zh) * | 2017-08-18 | 2019-02-21 | 四川百利药业有限责任公司 | 一种喜树碱-抗体偶联物 |
| WO2020063676A1 (zh) * | 2018-09-26 | 2020-04-02 | 江苏恒瑞医药股份有限公司 | 依喜替康类似物的配体-药物偶联物及其制备方法和应用 |
| CA3114474A1 (en) * | 2018-09-30 | 2020-04-02 | Jiangsu Hengrui Medicine Co., Ltd. | Anti-b7h3 antibody-exatecan analog conjugate and medicinal use thereof |
| CN113631580B (zh) * | 2019-02-03 | 2024-07-02 | 上海宝济药业股份有限公司 | 抗her2的双特异性抗体及其应用 |
-
2021
- 2021-08-13 EP EP21855628.0A patent/EP4183421A4/en active Pending
- 2021-08-13 CN CN202411649220.7A patent/CN119792562A/zh active Pending
- 2021-08-13 IL IL300446A patent/IL300446A/en unknown
- 2021-08-13 CA CA3188508A patent/CA3188508A1/en active Pending
- 2021-08-13 BR BR112023002417A patent/BR112023002417A2/pt unknown
- 2021-08-13 CN CN202411649235.3A patent/CN119792568A/zh active Pending
- 2021-08-13 CN CN202411649224.5A patent/CN119792563A/zh active Pending
- 2021-08-13 KR KR1020237007880A patent/KR20230051214A/ko active Pending
- 2021-08-13 CN CN202411649232.XA patent/CN119792567A/zh active Pending
- 2021-08-13 WO PCT/CN2021/112462 patent/WO2022033578A1/zh not_active Ceased
- 2021-08-13 CN CN202180041403.9A patent/CN115702008B/zh active Active
- 2021-08-13 JP JP2023508466A patent/JP2023537051A/ja active Pending
- 2021-08-13 AU AU2021323863A patent/AU2021323863A1/en active Pending
- 2021-08-13 CN CN202411649228.3A patent/CN119792565A/zh active Pending
- 2021-08-13 MX MX2023001648A patent/MX2023001648A/es unknown
- 2021-08-13 CN CN202411649225.XA patent/CN119792564A/zh active Pending
- 2021-08-13 US US18/040,498 patent/US20230405141A1/en active Pending
- 2021-08-13 CN CN202411649231.5A patent/CN119792566A/zh active Pending
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