JP2023535956A5 - - Google Patents
Info
- Publication number
- JP2023535956A5 JP2023535956A5 JP2023505687A JP2023505687A JP2023535956A5 JP 2023535956 A5 JP2023535956 A5 JP 2023535956A5 JP 2023505687 A JP2023505687 A JP 2023505687A JP 2023505687 A JP2023505687 A JP 2023505687A JP 2023535956 A5 JP2023535956 A5 JP 2023535956A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- vector according
- nucleic acid
- promoter
- aav vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063058437P | 2020-07-29 | 2020-07-29 | |
| US63/058,437 | 2020-07-29 | ||
| PCT/US2021/043582 WO2022026632A2 (en) | 2020-07-29 | 2021-07-28 | Improved aav-mediated x-linked retinoschisis therapies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023535956A JP2023535956A (ja) | 2023-08-22 |
| JP2023535956A5 true JP2023535956A5 (https=) | 2024-07-05 |
Family
ID=77726514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023505687A Pending JP2023535956A (ja) | 2020-07-29 | 2021-07-28 | 改善されたｘ連鎖性網膜分離症のａａｖ媒介療法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230265455A1 (https=) |
| EP (1) | EP4188450A2 (https=) |
| JP (1) | JP2023535956A (https=) |
| CN (1) | CN116568338A (https=) |
| AU (1) | AU2021319065A1 (https=) |
| CA (1) | CA3190214A1 (https=) |
| IL (1) | IL299927A (https=) |
| WO (1) | WO2022026632A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20240124893A1 (en) * | 2021-11-03 | 2024-04-18 | Teamedon International, Inc. | Methods of Treating Human X-Linked Retinoschisis Using Gene Therapy |
| EP4499847A4 (en) * | 2022-03-30 | 2026-03-25 | Univ Pittsburgh Commonwealth Sys Higher Education | Adeno-associated viral vectors for the delivery of nucleic acids across retinal regions |
| CN114848850B (zh) * | 2022-04-28 | 2023-12-15 | 武汉中眸生物科技有限责任公司 | Rs1基因在制备xlrs治疗剂中的应用及治疗剂 |
| CN118359687A (zh) * | 2023-01-18 | 2024-07-19 | 上海朗昇生物科技有限公司 | 一种新衣壳蛋白变体以及其用途 |
| EP4704920A1 (en) * | 2023-05-04 | 2026-03-11 | Abeona Therapeutics Inc. | Recombinant adeno-associated viral vectors for multipartite gene delivery and stargardt disease treatment |
| WO2025022144A1 (en) * | 2023-07-26 | 2025-01-30 | Sorbonne Universite | Chimeric promoter for targeted expression in aii amacrine cells |
| WO2025091025A1 (en) * | 2023-10-26 | 2025-05-01 | The Trustees Of The University Of Pennsylvania | Gene therapy for ocular disorders relating to sirt1 |
| WO2025113432A1 (zh) * | 2023-11-27 | 2025-06-05 | 北京因诺惟康医药科技有限公司 | 一种用于治疗x染色体连锁视网膜劈裂症的基因药物 |
| WO2025231339A1 (en) * | 2024-05-02 | 2025-11-06 | Avista Therapeutics, Inc. | Adeno-associated virus vectors for therapeutic nucleic acid delivery to retinal cells |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003274397A1 (en) | 2002-06-05 | 2003-12-22 | University Of Florida | Production of pseudotyped recombinant aav virions |
| US20120322861A1 (en) | 2007-02-23 | 2012-12-20 | Barry John Byrne | Compositions and Methods for Treating Diseases |
| US9567376B2 (en) * | 2013-02-08 | 2017-02-14 | The Trustees Of The University Of Pennsylvania | Enhanced AAV-mediated gene transfer for retinal therapies |
| WO2014127196A1 (en) * | 2013-02-15 | 2014-08-21 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Aav8 retinoschisin expression vector for treating x-linked retinoschisis |
| HK1220488A1 (zh) * | 2013-03-15 | 2017-05-05 | The Children's Hospital Of Philadelphia | 含有填充者/填充物多核苷酸序列的载体及其使用方法 |
| EP3113787B1 (en) * | 2014-03-04 | 2019-12-04 | University of Florida Research Foundation, Inc. | Improved raav vectors and methods for transduction of photoreceptors and rpe cells |
| EP3800191B1 (en) * | 2014-03-17 | 2025-08-20 | Adverum Biotechnologies, Inc. | Compositions and methods for enhanced gene expression in cone cells |
| PL3628334T3 (pl) * | 2014-03-21 | 2023-12-18 | Genzyme Corporation | Terapia genowa w retinopatii barwnikowej |
| US10533187B2 (en) | 2015-03-18 | 2020-01-14 | University Of Florida Research Foundation, Incorporated | Methods and compositions for restoration of cone function in BCM |
| CA3001594A1 (en) * | 2015-10-14 | 2017-04-20 | Audentes Therapeutics, Inc. | Nucleic acid molecules containing spacers and methods of use thereof |
| WO2017070491A1 (en) * | 2015-10-23 | 2017-04-27 | Applied Genetic Technologies Corporation | Ophthalmic formulations |
| EP3585883A4 (en) | 2017-02-21 | 2021-04-14 | University of Florida Research Foundation, Incorporated | MODIFIED AAV CAPSID PROTEINS AND USES THEREOF |
| US20210228738A1 (en) * | 2017-07-17 | 2021-07-29 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins |
| US20200390907A1 (en) * | 2018-01-22 | 2020-12-17 | The Usa, As Represented By The Secretary, Department Of Health And Human Services | Methods and compositions for treating genetically linked diseases of the eye |
| US12605466B2 (en) * | 2019-03-04 | 2026-04-21 | University Of Florida Research Foundation, Incorporated | Enhanced human opsin promoter for rod specific expression |
| US20220403417A1 (en) * | 2019-11-20 | 2022-12-22 | University Of Massachusetts | Aav-based delivery of thymine kinase 2 |
-
2021
- 2021-07-28 US US18/017,726 patent/US20230265455A1/en active Pending
- 2021-07-28 IL IL299927A patent/IL299927A/en unknown
- 2021-07-28 CN CN202180066643.4A patent/CN116568338A/zh active Pending
- 2021-07-28 WO PCT/US2021/043582 patent/WO2022026632A2/en not_active Ceased
- 2021-07-28 AU AU2021319065A patent/AU2021319065A1/en active Pending
- 2021-07-28 EP EP21769535.2A patent/EP4188450A2/en active Pending
- 2021-07-28 CA CA3190214A patent/CA3190214A1/en active Pending
- 2021-07-28 JP JP2023505687A patent/JP2023535956A/ja active Pending
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