JP2022523050A5 - - Google Patents

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Publication number
JP2022523050A5
JP2022523050A5 JP2021543230A JP2021543230A JP2022523050A5 JP 2022523050 A5 JP2022523050 A5 JP 2022523050A5 JP 2021543230 A JP2021543230 A JP 2021543230A JP 2021543230 A JP2021543230 A JP 2021543230A JP 2022523050 A5 JP2022523050 A5 JP 2022523050A5
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JP
Japan
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JP2021543230A
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Japanese (ja)
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JP7624727B2 (ja
JP2022523050A (ja
JPWO2020154535A5 (https=
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Publication of JPWO2020154535A5 publication Critical patent/JPWO2020154535A5/ja
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JP2021543230A 2019-01-23 2020-01-23 合理的設計により増強された新規なaavウイルスによる網膜における高効率の形質導入および側方への広がり Active JP7624727B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962795695P 2019-01-23 2019-01-23
US62/795,695 2019-01-23
PCT/US2020/014838 WO2020154535A1 (en) 2019-01-23 2020-01-23 Highly efficient transduction and lateral spread in the retina by a novel aav virus enhanced by rational design

Publications (4)

Publication Number Publication Date
JP2022523050A JP2022523050A (ja) 2022-04-21
JP2022523050A5 true JP2022523050A5 (https=) 2023-02-06
JPWO2020154535A5 JPWO2020154535A5 (https=) 2023-02-06
JP7624727B2 JP7624727B2 (ja) 2025-01-31

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ID=71737005

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021543230A Active JP7624727B2 (ja) 2019-01-23 2020-01-23 合理的設計により増強された新規なaavウイルスによる網膜における高効率の形質導入および側方への広がり

Country Status (7)

Country Link
US (1) US20220133909A1 (https=)
EP (1) EP3914229A4 (https=)
JP (1) JP7624727B2 (https=)
CN (1) CN113347962B (https=)
AU (1) AU2020212026B2 (https=)
CA (1) CA3125294A1 (https=)
WO (1) WO2020154535A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024223696A1 (en) * 2023-04-24 2024-10-31 Universiteit Gent Compounds to treat inherited retinal disease
CN121046460A (zh) * 2024-05-31 2025-12-02 上海朗昇生物科技有限公司 用于治疗Prom1相关视网膜疾病的新型治疗药物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2287495A1 (en) * 1997-04-21 1998-10-29 University Of Florida Materials and methods for treatment of retinal diseases
AU2003274397A1 (en) 2002-06-05 2003-12-22 University Of Florida Production of pseudotyped recombinant aav virions
WO2006110689A2 (en) * 2005-04-07 2006-10-19 The Trustees Of The University Of Pennsylvania Method of increasing the function of an aav vector
US20120322861A1 (en) 2007-02-23 2012-12-20 Barry John Byrne Compositions and Methods for Treating Diseases
HRP20190144T1 (hr) * 2010-04-23 2019-03-22 University Of Florida Research Foundation, Inc. Pripravci raav-gvanilat ciklaze i postupci za liječenje leberove urođene amauroze-1 (lca1)
ES2768763T3 (es) * 2014-03-04 2020-06-23 Univ Florida Vectores rAAV mejorados y métodos para la transducción de fotorreceptores y células EPR
IL248102B (en) * 2014-05-02 2022-07-01 Genzyme Corp aav vectors for gene therapy of the central nervous system and retina
WO2016149664A1 (en) 2015-03-18 2016-09-22 University Of Florida Research Foundation, Inc. Methods and compositions for restoration of cone function in bcm
JP6805174B2 (ja) * 2015-05-12 2020-12-23 アメリカ合衆国 神経成長因子シグナルペプチド及び副甲状腺ホルモンを含むaav分離株及び融合タンパク質
US20170348387A1 (en) * 2016-02-29 2017-12-07 The Trustees Of The University Of Pennsylvania Aav-mediated gene therapy for nphp5 lca-ciliopathy
PE20190401A1 (es) * 2016-07-26 2019-03-13 Biomarin Pharm Inc Novedosas proteinas de la capside del virus adenoasociado
AU2018224044B2 (en) 2017-02-21 2024-01-25 The Uab Research Foundation Modified AAV capsid proteins and uses thereof

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