JP2022523050A5 - - Google Patents
Info
- Publication number
- JP2022523050A5 JP2022523050A5 JP2021543230A JP2021543230A JP2022523050A5 JP 2022523050 A5 JP2022523050 A5 JP 2022523050A5 JP 2021543230 A JP2021543230 A JP 2021543230A JP 2021543230 A JP2021543230 A JP 2021543230A JP 2022523050 A5 JP2022523050 A5 JP 2022523050A5
- Authority
- JP
- Japan
- Prior art keywords
- acid sequence
- nucleic acid
- raav
- mammal
- therapeutic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962795695P | 2019-01-23 | 2019-01-23 | |
| US62/795,695 | 2019-01-23 | ||
| PCT/US2020/014838 WO2020154535A1 (en) | 2019-01-23 | 2020-01-23 | Highly efficient transduction and lateral spread in the retina by a novel aav virus enhanced by rational design |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022523050A JP2022523050A (ja) | 2022-04-21 |
| JP2022523050A5 true JP2022523050A5 (https=) | 2023-02-06 |
| JP7624727B2 JP7624727B2 (ja) | 2025-01-31 |
Family
ID=71737005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021543230A Active JP7624727B2 (ja) | 2019-01-23 | 2020-01-23 | 合理的設計により増強された新規なａａｖウイルスによる網膜における高効率の形質導入および側方への広がり |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220133909A1 (https=) |
| EP (1) | EP3914229A4 (https=) |
| JP (1) | JP7624727B2 (https=) |
| CN (1) | CN113347962B (https=) |
| AU (1) | AU2020212026B2 (https=) |
| CA (1) | CA3125294A1 (https=) |
| WO (1) | WO2020154535A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024223696A1 (en) * | 2023-04-24 | 2024-10-31 | Universiteit Gent | Compounds to treat inherited retinal disease |
| CN121046460A (zh) * | 2024-05-31 | 2025-12-02 | 上海朗昇生物科技有限公司 | 用于治疗Prom1相关视网膜疾病的新型治疗药物 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0977880A2 (en) * | 1997-04-21 | 2000-02-09 | University Of Florida | Materials and methods for treatment of retinal diseases |
| AU2003274397A1 (en) | 2002-06-05 | 2003-12-22 | University Of Florida | Production of pseudotyped recombinant aav virions |
| ES2525067T3 (es) * | 2005-04-07 | 2014-12-17 | The Trustees Of The University Of Pennsylvania | Método de incremento de la función de un vector de AAV |
| US20120322861A1 (en) | 2007-02-23 | 2012-12-20 | Barry John Byrne | Compositions and Methods for Treating Diseases |
| SG10201800541SA (en) | 2010-04-23 | 2018-03-28 | Univ Florida | Raav-guanylate cyclase compositions and methods for treating leber's congenital amaurosis-1 (lca1) |
| EP3113787B1 (en) * | 2014-03-04 | 2019-12-04 | University of Florida Research Foundation, Inc. | Improved raav vectors and methods for transduction of photoreceptors and rpe cells |
| LT3137497T (lt) * | 2014-05-02 | 2021-07-26 | Genzyme Corporation | Aav vektoriai, skirti tinklainės ir cns genų terapijai |
| US10533187B2 (en) | 2015-03-18 | 2020-01-14 | University Of Florida Research Foundation, Incorporated | Methods and compositions for restoration of cone function in BCM |
| JP6805174B2 (ja) | 2015-05-12 | 2020-12-23 | アメリカ合衆国 | 神経成長因子シグナルペプチド及び副甲状腺ホルモンを含むａａｖ分離株及び融合タンパク質 |
| US20170348387A1 (en) | 2016-02-29 | 2017-12-07 | The Trustees Of The University Of Pennsylvania | Aav-mediated gene therapy for nphp5 lca-ciliopathy |
| IL305149A (en) * | 2016-07-26 | 2023-10-01 | Biomarin Pharm Inc | Novel adeno-associated virus capsid proteins |
| EP3585883A4 (en) | 2017-02-21 | 2021-04-14 | University of Florida Research Foundation, Incorporated | MODIFIED AAV CAPSID PROTEINS AND USES THEREOF |
-
2020
- 2020-01-23 EP EP20744697.2A patent/EP3914229A4/en active Pending
- 2020-01-23 US US17/425,292 patent/US20220133909A1/en active Pending
- 2020-01-23 WO PCT/US2020/014838 patent/WO2020154535A1/en not_active Ceased
- 2020-01-23 CA CA3125294A patent/CA3125294A1/en active Pending
- 2020-01-23 CN CN202080010452.1A patent/CN113347962B/zh active Active
- 2020-01-23 JP JP2021543230A patent/JP7624727B2/ja active Active
- 2020-01-23 AU AU2020212026A patent/AU2020212026B2/en active Active
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