JP2023513004A5 - - Google Patents

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Publication number
JP2023513004A5
JP2023513004A5 JP2022545976A JP2022545976A JP2023513004A5 JP 2023513004 A5 JP2023513004 A5 JP 2023513004A5 JP 2022545976 A JP2022545976 A JP 2022545976A JP 2022545976 A JP2022545976 A JP 2022545976A JP 2023513004 A5 JP2023513004 A5 JP 2023513004A5
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JP
Japan
Application number
JP2022545976A
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Japanese (ja)
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JPWO2021155137A5 (https=
JP2023513004A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/015695 external-priority patent/WO2021155137A1/en
Publication of JP2023513004A publication Critical patent/JP2023513004A/ja
Publication of JP2023513004A5 publication Critical patent/JP2023513004A5/ja
Publication of JPWO2021155137A5 publication Critical patent/JPWO2021155137A5/ja
Pending legal-status Critical Current

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JP2022545976A 2020-01-29 2021-01-29 眼科遺伝子療法のための改変されたアデノ随伴ウイルスカプシドタンパク質およびその使用方法 Pending JP2023513004A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062967416P 2020-01-29 2020-01-29
US62/967,416 2020-01-29
PCT/US2021/015695 WO2021155137A1 (en) 2020-01-29 2021-01-29 Modified adeno-associated viral capsid proteins for ocular gene therapy and methods of use thereof

Publications (3)

Publication Number Publication Date
JP2023513004A JP2023513004A (ja) 2023-03-30
JP2023513004A5 true JP2023513004A5 (https=) 2024-02-02
JPWO2021155137A5 JPWO2021155137A5 (https=) 2024-02-02

Family

ID=74673421

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022545976A Pending JP2023513004A (ja) 2020-01-29 2021-01-29 眼科遺伝子療法のための改変されたアデノ随伴ウイルスカプシドタンパク質およびその使用方法

Country Status (15)

Country Link
US (1) US20210261625A1 (https=)
EP (1) EP4097121A1 (https=)
JP (1) JP2023513004A (https=)
KR (1) KR20220133941A (https=)
CN (1) CN115989234A (https=)
AR (1) AR121228A1 (https=)
AU (1) AU2021213786A1 (https=)
BR (1) BR112022014852A2 (https=)
CA (1) CA3165019A1 (https=)
CO (1) CO2022010227A2 (https=)
IL (1) IL294868A (https=)
MX (1) MX2022009252A (https=)
PH (1) PH12022551878A1 (https=)
TW (1) TW202142552A (https=)
WO (1) WO2021155137A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2024004217A (es) 2021-10-08 2024-06-26 Dyno Therapeutics Inc Variantes de cápside y métodos de uso de estas.
EP4551253A1 (en) 2022-07-08 2025-05-14 Ospedale San Raffaele S.r.l. Transgene cassettes
EP4303226A1 (en) 2022-07-08 2024-01-10 Ospedale San Raffaele S.r.l. Transgene cassettes and epigenetic silencers for the treatment of disorders
KR102901502B1 (ko) 2024-06-27 2025-12-18 이엔셀 주식회사 안구 세포 또는 조직을 표적하는 펩타이드 및 이를 포함하는 바이러스 캡시드 단백질 및 바이러스 벡터

Family Cites Families (18)

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AU722624B2 (en) 1996-09-06 2000-08-10 Trustees Of The University Of Pennsylvania, The An inducible method for production of recombinant adeno-associated viruses utilizing T7 polymerase
US6225291B1 (en) 1997-04-21 2001-05-01 University Of Florida Rod opsin mRNA-specific ribozyme compositions and methods for the treatment of retinal diseases
US6995006B2 (en) 1997-09-05 2006-02-07 Targeted Genetics Corporation Methods for generating high titer helper-free preparations of released recombinant AAV vectors
US6566118B1 (en) 1997-09-05 2003-05-20 Targeted Genetics Corporation Methods for generating high titer helper-free preparations of released recombinant AAV vectors
US6723551B2 (en) 2001-11-09 2004-04-20 The United States Of America As Represented By The Department Of Health And Human Services Production of adeno-associated virus in insect cells
DE602004030327D1 (de) 2003-05-21 2011-01-13 Genzyme Corp Verfahren zur herstellung von präparationen rekombinanter aav-virionen, die weitgehend frei von leeren capsiden sind
DK2191001T3 (en) 2007-04-09 2016-09-19 Univ Florida RAAV VECTOR COMPOSITIONS WITH TYROSIN MODIFIED CAPSIDE PROTEINS AND PROCEDURES FOR USE THEREOF
US20100081707A1 (en) 2008-02-21 2010-04-01 Ali Robin R Devices and methods for delivering polynucleotides into retinal cells of the macula and fovea
HUE028341T2 (en) 2009-06-16 2016-12-28 Genzyme Corp Improved methods for purification of recombinant aav vectors
EP2826860B1 (en) 2010-04-23 2018-08-22 University of Massachusetts CNS targeting AAV vectors and methods of use thereof
WO2012109570A1 (en) * 2011-02-10 2012-08-16 The University Of North Carolina At Chapel Hill Viral vectors with modified transduction profiles and methods of making and using the same
GB201403684D0 (en) * 2014-03-03 2014-04-16 King S College London Vector
FI3628334T3 (fi) * 2014-03-21 2023-09-15 Genzyme Corp Geenihoito verkkokalvon pigmenttirappeuma
IL248102B (en) * 2014-05-02 2022-07-01 Genzyme Corp aav vectors for gene therapy of the central nervous system and retina
AU2015335923B2 (en) * 2014-10-21 2021-04-29 University Of Massachusetts Recombinant AAV variants and uses thereof
NZ791267A (en) 2016-08-15 2025-11-28 Genzyme Corp Methods for detecting AAV
US20190262373A1 (en) * 2016-08-16 2019-08-29 The University Of North Carolina At Chapel Hill Methods and compositions for targeted gene transfer
US12338267B2 (en) * 2018-05-15 2025-06-24 President And Fellows Of Harvard College Viral vectors exhibiting improved gene delivery properties

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