JP2023535701A5 - - Google Patents
Info
- Publication number
- JP2023535701A5 JP2023535701A5 JP2023504063A JP2023504063A JP2023535701A5 JP 2023535701 A5 JP2023535701 A5 JP 2023535701A5 JP 2023504063 A JP2023504063 A JP 2023504063A JP 2023504063 A JP2023504063 A JP 2023504063A JP 2023535701 A5 JP2023535701 A5 JP 2023535701A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- optionally substituted
- compound according
- compounds
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025266591A JP2026053472A (ja) | 2020-07-20 | 2025-12-19 | 抗ウイルス剤としての官能化ペプチド |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063054048P | 2020-07-20 | 2020-07-20 | |
| US63/054,048 | 2020-07-20 | ||
| PCT/US2021/042193 WO2022020242A1 (en) | 2020-07-20 | 2021-07-19 | Functionalized peptides as antiviral agents |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025266591A Division JP2026053472A (ja) | 2020-07-20 | 2025-12-19 | 抗ウイルス剤としての官能化ペプチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023535701A JP2023535701A (ja) | 2023-08-21 |
| JP2023535701A5 true JP2023535701A5 (https=) | 2024-07-17 |
| JP7795521B2 JP7795521B2 (ja) | 2026-01-07 |
Family
ID=79729492
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023504063A Active JP7795521B2 (ja) | 2020-07-20 | 2021-07-19 | 抗ウイルス剤としての官能化ペプチド |
| JP2025266591A Pending JP2026053472A (ja) | 2020-07-20 | 2025-12-19 | 抗ウイルス剤としての官能化ペプチド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025266591A Pending JP2026053472A (ja) | 2020-07-20 | 2025-12-19 | 抗ウイルス剤としての官能化ペプチド |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US20220033383A1 (https=) |
| EP (2) | EP4635972A3 (https=) |
| JP (2) | JP7795521B2 (https=) |
| KR (1) | KR20230069090A (https=) |
| CN (1) | CN116348477A (https=) |
| AU (1) | AU2021313130A1 (https=) |
| BR (1) | BR112022026899A2 (https=) |
| CA (1) | CA3173964A1 (https=) |
| CL (1) | CL2023000167A1 (https=) |
| CO (1) | CO2023000199A2 (https=) |
| DE (3) | DE202021004113U1 (https=) |
| ES (2) | ES2936277B2 (https=) |
| GB (2) | GB2607514B (https=) |
| HR (1) | HRP20251116T1 (https=) |
| HU (1) | HUE21846991T1 (https=) |
| IL (1) | IL300027A (https=) |
| MX (1) | MX2023000798A (https=) |
| PL (1) | PL4051265T3 (https=) |
| RS (1) | RS67201B1 (https=) |
| SM (1) | SMT202500351T1 (https=) |
| WO (1) | WO2022020242A1 (https=) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11124497B1 (en) | 2020-04-17 | 2021-09-21 | Pardes Biosciences, Inc. | Inhibitors of cysteine proteases and methods of use thereof |
| US11174231B1 (en) | 2020-06-09 | 2021-11-16 | Pardes Biosciences, Inc. | Inhibitors of cysteine proteases and methods of use thereof |
| PH12022553378A1 (en) * | 2020-06-10 | 2024-03-25 | Univ Leuven Kath | Anti-viral compounds for treating coronavirus, picornavirus, and norovirus infections |
| JP2023533016A (ja) | 2020-07-11 | 2023-08-01 | ファイザー・インク | 抗ウイルス性ヘテロアリールケトン誘導体 |
| US11351149B2 (en) | 2020-09-03 | 2022-06-07 | Pfizer Inc. | Nitrile-containing antiviral compounds |
| US12540141B2 (en) | 2020-11-23 | 2026-02-03 | Enanta Pharmaceuticals, Inc. | Spiropyrrolidine derived antiviral agents |
| KR20230124583A (ko) | 2020-11-23 | 2023-08-25 | 이난타 파마슈티칼스, 인코포레이티드 | 신규한 스피로피롤리딘 유래 항바이러스제 |
| RS66213B1 (sr) * | 2021-04-16 | 2024-12-31 | Fujian Akeylink Biotechnology Co Ltd | Jedinjenje kratkog peptida prolina modifikovanog prstenom i upotreba istog |
| WO2022235605A1 (en) | 2021-05-04 | 2022-11-10 | Enanta Pharmaceuticals, Inc. | Novel macrocyclic antiviral agents |
| US12398147B2 (en) | 2021-05-11 | 2025-08-26 | Enanta Pharmaceuticals, Inc. | Macrocyclic spiropyrrolidine derived antiviral agents |
| WO2022251615A1 (en) | 2021-05-28 | 2022-12-01 | Arun K Ghosh | Compounds for the treatment of sars |
| US20230033285A1 (en) * | 2021-06-16 | 2023-02-02 | The Scripps Research Institute | Protease Inhibitors for Treatment of Coronavirus Infections |
| AU2022306289A1 (en) | 2021-07-09 | 2024-01-18 | Aligos Therapeutics, Inc. | Anti-viral compounds |
| US12479854B2 (en) | 2021-07-29 | 2025-11-25 | Enanta Pharmaceuticals, Inc. | Spiropyrrolidine derived antiviral agents |
| WO2023043816A1 (en) | 2021-09-17 | 2023-03-23 | Aligos Therapeutics, Inc. | Anti-viral compounds for treating coronavirus, picornavirus, and norovirus infections |
| US11912714B2 (en) | 2021-11-12 | 2024-02-27 | Enanta Pharmaceuticals, Inc. | Spiropyrrolidine derived antiviral agents |
| US11858945B2 (en) | 2021-11-12 | 2024-01-02 | Enanta Pharmaceuticals, Inc. | Alkyne-containing antiviral agents |
| US11919910B2 (en) | 2021-11-12 | 2024-03-05 | Enanta Pharmaceuticals, Inc. | Spiropyrrolidine derived antiviral agents |
| WO2023088418A1 (en) * | 2021-11-20 | 2023-05-25 | Fochon Biosciences, Ltd. | Compounds as sars-cov-2 inhibitors |
| WO2023107419A1 (en) | 2021-12-08 | 2023-06-15 | Enanta Pharmaceuticals, Inc. | Saturated spirocyclics as antiviral agents |
| US12145941B2 (en) | 2021-12-08 | 2024-11-19 | Enanta Pharmaceuticals, Inc. | Heterocyclic antiviral agents |
| WO2023116811A1 (zh) * | 2021-12-22 | 2023-06-29 | 福建广生中霖生物科技有限公司 | 含β-胺基酮的短肽化合物及其应用 |
| TW202334123A (zh) * | 2021-12-31 | 2023-09-01 | 大陸商蘇州愛科百發生物醫藥技術有限公司 | 用於預防和治療冠狀病毒感染的化合物及其偶聯物和方法 |
| WO2023137007A1 (en) | 2022-01-11 | 2023-07-20 | Enanta Pharmaceuticals, Inc. | Processes for the preparation of 4,6,7-trifluoro-1h-indole-2-carboxylic acid |
| CN118451090A (zh) * | 2022-01-13 | 2024-08-06 | 海南先声药业有限公司 | 一种酰胺类抗病毒化合物 |
| US11760722B2 (en) | 2022-01-18 | 2023-09-19 | Ascletis Bioscience Co., Ltd. | Inhibitors of cysteine proteases and methods of use thereof |
| CN114230504B (zh) * | 2022-02-24 | 2022-06-03 | 南京桦冠生物技术有限公司 | 一种吡咯烷酮中间体的合成方法 |
| CN116768967A (zh) * | 2022-03-07 | 2023-09-19 | 广州谷森制药有限公司 | 氘代内酰胺类化合物及其制备方法、组合物和用途 |
| CN117143082A (zh) * | 2022-03-07 | 2023-12-01 | 广州国家实验室 | 用作3c样蛋白酶抑制剂的氮杂双环[3.1.0]己烷衍生物 |
| CN114957383B (zh) * | 2022-04-01 | 2024-12-31 | 中国科学院上海药物研究所 | 一种拟肽类化合物及其制备方法、药物组合物和用途 |
| WO2023196307A1 (en) | 2022-04-05 | 2023-10-12 | Enanta Pharmaceuticals, Inc. | Novel spiropyrrolidine derived antiviral agents |
| CN117164582A (zh) * | 2022-05-31 | 2023-12-05 | 周龙兴 | 一种蛋白酶抑制剂及其药物组合物和用途 |
| CN117362213A (zh) * | 2022-06-30 | 2024-01-09 | 武汉瑞晟药业有限公司 | 一种吡咯烷酮中间体的制备方法 |
| WO2024059087A1 (en) * | 2022-09-13 | 2024-03-21 | Takeda Pharmaceutical Company Limited | 3-(1h-indole-2-carbonyl)-6,6-dimethyl-n-((s)-1-oxo-3-((s)-2-oxopyrrolidin-3-yl)p ropan-2-yl)-3-azabicyclo[3.1.0]hexane-2-carboxamide derivatives as mpro inhibitors for the treatment of coronavirus infections |
| WO2024107778A1 (en) * | 2022-11-15 | 2024-05-23 | Takeda Pharmaceutical Company Limited | Novel protease inhibitors for treatment of coronavirus infections |
| KR20250109233A (ko) * | 2022-11-22 | 2025-07-16 | 머크 샤프 앤드 돔 엘엘씨 | 코로나바이러스 감염을 치료 또는 예방하기 위한 프로테아제 억제제로서의 2-아미노-n-(4-아미노-3,4-디옥소-1-(2-옥소피롤리딘-3-일)부탄-2-일)벤즈아미드 유도체 |
| EP4501942A1 (en) | 2023-08-02 | 2025-02-05 | Consejo Superior De Investigaciones Científicas (CSIC) | Peptidomimetics with antiviral activity |
| WO2025125695A2 (en) | 2024-12-17 | 2025-06-19 | Medchemica Consultancy Ltd | Chemical compoundsid50000167790940 p. doc 2025-05-07 filing no.:19 |
Family Cites Families (66)
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| US5508269A (en) | 1994-10-19 | 1996-04-16 | Pathogenesis Corporation | Aminoglycoside formulation for aerosolization |
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| US5767068A (en) | 1997-02-13 | 1998-06-16 | Pathogenesis Corporation | Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections |
| DK1385870T3 (da) * | 2000-07-21 | 2010-07-05 | Schering Corp | Peptider som inhibitorer af NS3-serinprotease fra hepatitis C-virus |
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| ATE382686T1 (de) | 2003-05-13 | 2008-01-15 | Univ Luebeck | Kristallstruktur von der humanen coronavirus 229e hauptproteinase und deren verwendung zur entwicklung von sars-inhibitoren |
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-
2021
- 2021-07-19 US US17/379,409 patent/US20220033383A1/en not_active Abandoned
- 2021-07-19 PL PL21846991.4T patent/PL4051265T3/pl unknown
- 2021-07-19 HU HUE21846991A patent/HUE21846991T1/hu unknown
- 2021-07-19 ES ES202290062A patent/ES2936277B2/es active Active
- 2021-07-19 ES ES21846991T patent/ES2922973T3/es active Active
- 2021-07-19 KR KR1020237005438A patent/KR20230069090A/ko active Pending
- 2021-07-19 DE DE202021004113.3U patent/DE202021004113U1/de active Active
- 2021-07-19 IL IL300027A patent/IL300027A/en unknown
- 2021-07-19 WO PCT/US2021/042193 patent/WO2022020242A1/en not_active Ceased
- 2021-07-19 EP EP25185114.3A patent/EP4635972A3/en active Pending
- 2021-07-19 RS RS20250906A patent/RS67201B1/sr unknown
- 2021-07-19 BR BR112022026899A patent/BR112022026899A2/pt not_active Application Discontinuation
- 2021-07-19 EP EP21846991.4A patent/EP4051265B1/en active Active
- 2021-07-19 CN CN202180059223.3A patent/CN116348477A/zh active Pending
- 2021-07-19 GB GB2211934.1A patent/GB2607514B/en active Active
- 2021-07-19 HR HRP20251116TT patent/HRP20251116T1/hr unknown
- 2021-07-19 DE DE112021000413.1T patent/DE112021000413B4/de active Active
- 2021-07-19 JP JP2023504063A patent/JP7795521B2/ja active Active
- 2021-07-19 DE DE21846991.4T patent/DE21846991T1/de active Pending
- 2021-07-19 SM SM20250351T patent/SMT202500351T1/it unknown
- 2021-07-19 MX MX2023000798A patent/MX2023000798A/es unknown
- 2021-07-19 GB GB2306834.9A patent/GB2619610B/en active Active
- 2021-07-19 CA CA3173964A patent/CA3173964A1/en active Pending
- 2021-07-19 AU AU2021313130A patent/AU2021313130A1/en active Pending
- 2021-10-21 US US17/506,981 patent/US20220041652A1/en not_active Abandoned
- 2021-11-09 US US17/522,176 patent/US11358953B2/en active Active
-
2023
- 2023-01-11 CO CONC2023/0000199A patent/CO2023000199A2/es unknown
- 2023-01-18 CL CL2023000167A patent/CL2023000167A1/es unknown
-
2025
- 2025-12-19 JP JP2025266591A patent/JP2026053472A/ja active Pending
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