JP2022512736A5 - - Google Patents

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Publication number
JP2022512736A5
JP2022512736A5 JP2021521145A JP2021521145A JP2022512736A5 JP 2022512736 A5 JP2022512736 A5 JP 2022512736A5 JP 2021521145 A JP2021521145 A JP 2021521145A JP 2021521145 A JP2021521145 A JP 2021521145A JP 2022512736 A5 JP2022512736 A5 JP 2022512736A5
Authority
JP
Japan
Application number
JP2021521145A
Other languages
Japanese (ja)
Other versions
JPWO2020079165A5 (https=
JP2022512736A (ja
JP7603199B2 (ja
Filing date
Publication date
Priority claimed from GBGB1816998.7A external-priority patent/GB201816998D0/en
Priority claimed from GBGB1909695.7A external-priority patent/GB201909695D0/en
Application filed filed Critical
Priority claimed from PCT/EP2019/078250 external-priority patent/WO2020079165A1/en
Publication of JP2022512736A publication Critical patent/JP2022512736A/ja
Publication of JPWO2020079165A5 publication Critical patent/JPWO2020079165A5/ja
Publication of JP2022512736A5 publication Critical patent/JP2022512736A5/ja
Priority to JP2024107578A priority Critical patent/JP2024150488A/ja
Application granted granted Critical
Publication of JP7603199B2 publication Critical patent/JP7603199B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021521145A 2018-10-18 2019-10-17 重水素を含有する化合物 Active JP7603199B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024107578A JP2024150488A (ja) 2018-10-18 2024-07-03 重水素を含有する化合物

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1816998.7 2018-10-18
GBGB1816998.7A GB201816998D0 (en) 2018-10-18 2018-10-18 Compounds
GB1909695.7 2019-07-05
GBGB1909695.7A GB201909695D0 (en) 2019-07-05 2019-07-05 Compounds
PCT/EP2019/078250 WO2020079165A1 (en) 2018-10-18 2019-10-17 Compounds containing deuterium

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024107578A Division JP2024150488A (ja) 2018-10-18 2024-07-03 重水素を含有する化合物

Publications (4)

Publication Number Publication Date
JP2022512736A JP2022512736A (ja) 2022-02-07
JPWO2020079165A5 JPWO2020079165A5 (https=) 2022-10-18
JP2022512736A5 true JP2022512736A5 (https=) 2022-10-18
JP7603199B2 JP7603199B2 (ja) 2024-12-20

Family

ID=68290247

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021521145A Active JP7603199B2 (ja) 2018-10-18 2019-10-17 重水素を含有する化合物
JP2024107578A Pending JP2024150488A (ja) 2018-10-18 2024-07-03 重水素を含有する化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024107578A Pending JP2024150488A (ja) 2018-10-18 2024-07-03 重水素を含有する化合物

Country Status (19)

Country Link
US (2) US12152087B2 (https=)
EP (1) EP3866931B1 (https=)
JP (2) JP7603199B2 (https=)
KR (1) KR102848971B1 (https=)
CN (1) CN112930214B (https=)
AU (1) AU2019362389B2 (https=)
BR (1) BR112021007060A2 (https=)
CA (1) CA3116198A1 (https=)
DK (1) DK3866931T3 (https=)
ES (1) ES2942468T3 (https=)
FI (1) FI3866931T3 (https=)
HU (1) HUE061801T2 (https=)
IL (1) IL282231B2 (https=)
MA (1) MA53904A (https=)
MX (1) MX2021004474A (https=)
PL (1) PL3866931T3 (https=)
SG (1) SG11202103726RA (https=)
WO (1) WO2020079165A1 (https=)
ZA (1) ZA202102492B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201905477D0 (en) * 2019-04-17 2019-05-29 Oncopeptides Ab Novel formulations
EP4347615B1 (en) * 2021-06-01 2025-05-21 Synthon B.V. Process for making melflufen or a salt thereof
GB202109895D0 (en) 2021-07-08 2021-08-25 Oncopeptides Ab Novel treatments
GB202109894D0 (en) 2021-07-08 2021-08-25 Oncopeptides Ab Novel treatments
WO2023281007A1 (en) 2021-07-08 2023-01-12 Oncopeptides Ab Melflufen for use in the treatment of multiple myeloma
GB202109896D0 (en) 2021-07-08 2021-08-25 Oncopeptides Ab Novel treatments
GB202204171D0 (en) 2022-03-24 2022-05-11 Oncopeptides Ab Novel formulations
WO2026057823A1 (en) * 2024-09-13 2026-03-19 Oncopeptides Ab Bis-chloroethylamino derivatives for treating leukemia

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0002202D0 (sv) 2000-06-13 2000-06-13 Karolinska Innovations Ab New peptides
WO2010044981A2 (en) 2008-09-18 2010-04-22 Auspex Pharmaceutical ,Inc. Benzoquinoline inhibitors of vesicular monoamine transporter 2
CA2801061A1 (en) 2010-06-01 2011-12-08 Auspex Pharmaceuticals, Inc. Benzoquinolone inhibitors of vmat2
CA3024230C (en) * 2011-04-28 2022-10-18 Oncopeptides Ab Lyophilized preparation of cytotoxic dipeptides
CN104684555A (zh) 2012-09-18 2015-06-03 奥斯拜客斯制药有限公司 囊泡单胺转运体2的氘化苯并喹啉抑制剂的制剂药代动力学
WO2014065751A1 (en) * 2012-10-26 2014-05-01 Oncopeptides Ab Lyophilized preparations of melphalan flufenamide
EA202091397A1 (ru) 2013-01-31 2020-09-04 Ауспекс Фармацетикалс, Инк. Бензохинолоновые ингибиторы vmat2
KR20150115807A (ko) * 2013-02-05 2015-10-14 임파 악치엔게젤샤프트 위치-특이적 비대칭 중수소 풍부 카테콜아민 유도체 및 상기 화합물을 포함하는 약제
EA201791466A1 (ru) 2013-12-03 2017-11-30 Оспекс Фармасьютикалз, Инк. Способы получения соединений бензохинолина
CN110229159B (zh) * 2013-12-18 2021-08-24 康塞特医药品有限公司 卢索替尼的氘代衍生物
HRP20221106T1 (hr) 2015-03-06 2022-11-25 Auspex Pharmaceuticals, Inc. Postupci liječenja abnormalnih nevoljnih poremećaja pokreta
GB201507903D0 (en) * 2015-05-08 2015-06-24 Oncopeptides Ab Process for preparation of nitrogen mustard derivatives
GB201521217D0 (en) * 2015-12-01 2016-01-13 Oncopeptides Ab Dosage regimens

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