JP2023534189A5 - - Google Patents

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Publication number
JP2023534189A5
JP2023534189A5 JP2023501424A JP2023501424A JP2023534189A5 JP 2023534189 A5 JP2023534189 A5 JP 2023534189A5 JP 2023501424 A JP2023501424 A JP 2023501424A JP 2023501424 A JP2023501424 A JP 2023501424A JP 2023534189 A5 JP2023534189 A5 JP 2023534189A5
Authority
JP
Japan
Prior art keywords
alkyl
aryl
group
aliphatic
cycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023501424A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023534189A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/041184 external-priority patent/WO2022011318A1/en
Publication of JP2023534189A publication Critical patent/JP2023534189A/ja
Publication of JP2023534189A5 publication Critical patent/JP2023534189A5/ja
Pending legal-status Critical Current

Links

JP2023501424A 2020-07-10 2021-07-09 Gabaaアルファ5アゴニストおよびsv2a阻害剤の組合せ物ならびに認知障害の処置において使用する方法 Pending JP2023534189A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063050730P 2020-07-10 2020-07-10
US63/050,730 2020-07-10
PCT/US2021/041184 WO2022011318A1 (en) 2020-07-10 2021-07-09 Combinations of gabaa alpha 5 agonists and sv2a inhibitors and methods of using in the treatment of cognitive impairment

Publications (2)

Publication Number Publication Date
JP2023534189A JP2023534189A (ja) 2023-08-08
JP2023534189A5 true JP2023534189A5 (https=) 2024-07-17

Family

ID=79552105

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023501424A Pending JP2023534189A (ja) 2020-07-10 2021-07-09 Gabaaアルファ5アゴニストおよびsv2a阻害剤の組合せ物ならびに認知障害の処置において使用する方法

Country Status (10)

Country Link
US (2) US20230270753A1 (https=)
EP (1) EP4178582A4 (https=)
JP (1) JP2023534189A (https=)
CN (1) CN116075302A (https=)
AU (1) AU2021304356A1 (https=)
BR (1) BR112023000423A2 (https=)
CA (1) CA3189302A1 (https=)
IL (1) IL299754A (https=)
MX (1) MX2023000405A (https=)
WO (1) WO2022011318A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7737721B2 (ja) * 2019-12-19 2025-09-11 エージンバイオ, インコーポレイテッド 認知障害を処置するためのベンゾジアゼピン誘導体、組成物および方法
EP4504176A1 (en) * 2022-04-01 2025-02-12 Agenebio, Inc. Methods for preventing or slowing the progression of cognitive decline or impairment in subjects displaying normal cognitive performance
CN120584115A (zh) 2022-08-19 2025-09-02 艾吉因生物股份有限公司 苯并氮杂䓬衍生物、组合物和用于治疗认知损害的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2865504T3 (es) * 2008-10-16 2021-10-15 Univ Johns Hopkins Procedimientos y composiciones para la mejora de la función cognitiva
AU2011215870B2 (en) * 2010-02-09 2016-01-28 The Johns Hopkins University Methods and compositions for improving cognitive function
US20140206667A1 (en) * 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
WO2014153180A1 (en) * 2013-03-14 2014-09-25 Michela Gallagher Methods and compositions for improving cognitive function
NZ760341A (en) * 2013-12-20 2021-12-24 Agenebio Inc Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment
US20180170941A1 (en) * 2016-12-19 2018-06-21 Agenebio, Inc. Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment
CN112601749B (zh) * 2018-06-19 2024-03-26 艾吉因生物股份有限公司 用于治疗认知损害的苯并二氮杂环庚三烯衍生物,组合物和方法

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